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Pilocarpine-induced shift of an accommodating intraocular lens : AT-45 Crystalens

Identifieur interne : 000B03 ( PascalFrancis/Checkpoint ); précédent : 000B02; suivant : 000B04

Pilocarpine-induced shift of an accommodating intraocular lens : AT-45 Crystalens

Auteurs : Christina Koeppl [Autriche] ; Oliver Findl [Autriche] ; Rupert Menapace [Autriche] ; Katharina Kriechbaum [Autriche] ; Matthias Wirtitsch [Autriche] ; Wolf Buehl [Autriche] ; Stefan Sacu [Autriche] ; Wolfgang Drexler [Autriche]

Source :

RBID : Pascal:05-0399236

Descripteurs français

English descriptors

Abstract

Purpose: To measure the shift of an accommodating plate-haptic intraocular lens (IOL) along the visual axis induced by ciliary muscle contraction after application of pilocarpine. Setting: Department of Ophthalmology, Medical University of Vienna, Vienna, Austria. Methods: Fifty-four eyes of 28 patients with age-related cataract comprised this prospective study. Each patient received an AT-45 silicone accommodating IOL (Crystalens, Eyeonics Corp.) after standardized cataract surgery. In a subgroup of 24 eyes, capsular bag fibrosis was reduced by extensive polishing of the anterior capsule with a slit cannula. Assessment included measurements of anterior chamber depth, assessed with partial coherence interferometry, before and after application of pilocarpine 2% and evaluation of near visual acuity 1 month and 3 months postoperatively. Results: A slight backward shift of the IOL of 151 μm in the nonpolished group (P<.001) and 122 μm in the polished group (P<.005) could be detected after application of pilocarpine. Polishing the capsule did not influence IOL shift. The median near visual acuity with distance correction 1 month and 3 months postoperatively was J5 and J4, respectively, in the nonpolished group and J6 at both times in the polished group. Conclusions: Pilocarpine induced a counterproductive active backward shift of the AT-45 IOL. Polishing of the capsular bag had no impact on accommodative ability. The reading performance of patients with the AT-45 IOL patients at 1 and 3 months was not significantly different from that of with a standard IOL under similar testing methods.


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Pascal:05-0399236

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<div type="abstract" xml:lang="en">Purpose: To measure the shift of an accommodating plate-haptic intraocular lens (IOL) along the visual axis induced by ciliary muscle contraction after application of pilocarpine. Setting: Department of Ophthalmology, Medical University of Vienna, Vienna, Austria. Methods: Fifty-four eyes of 28 patients with age-related cataract comprised this prospective study. Each patient received an AT-45 silicone accommodating IOL (Crystalens, Eyeonics Corp.) after standardized cataract surgery. In a subgroup of 24 eyes, capsular bag fibrosis was reduced by extensive polishing of the anterior capsule with a slit cannula. Assessment included measurements of anterior chamber depth, assessed with partial coherence interferometry, before and after application of pilocarpine 2% and evaluation of near visual acuity 1 month and 3 months postoperatively. Results: A slight backward shift of the IOL of 151 μm in the nonpolished group (P<.001) and 122 μm in the polished group (P<.005) could be detected after application of pilocarpine. Polishing the capsule did not influence IOL shift. The median near visual acuity with distance correction 1 month and 3 months postoperatively was J5 and J4, respectively, in the nonpolished group and J6 at both times in the polished group. Conclusions: Pilocarpine induced a counterproductive active backward shift of the AT-45 IOL. Polishing of the capsular bag had no impact on accommodative ability. The reading performance of patients with the AT-45 IOL patients at 1 and 3 months was not significantly different from that of with a standard IOL under similar testing methods.</div>
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<s5>03</s5>
</fC03>
<fC03 i1="02" i2="X" l="SPA">
<s0>Lente intraocular</s0>
<s5>03</s5>
</fC03>
<fC03 i1="03" i2="X" l="FRE">
<s0>Chirurgie</s0>
<s5>05</s5>
</fC03>
<fC03 i1="03" i2="X" l="ENG">
<s0>Surgery</s0>
<s5>05</s5>
</fC03>
<fC03 i1="03" i2="X" l="SPA">
<s0>Cirugía</s0>
<s5>05</s5>
</fC03>
<fC03 i1="04" i2="X" l="FRE">
<s0>Ophtalmologie</s0>
<s5>06</s5>
</fC03>
<fC03 i1="04" i2="X" l="ENG">
<s0>Ophthalmology</s0>
<s5>06</s5>
</fC03>
<fC03 i1="04" i2="X" l="SPA">
<s0>Oftalmología</s0>
<s5>06</s5>
</fC03>
<fC03 i1="05" i2="X" l="FRE">
<s0>Antiglaucomateux</s0>
<s5>25</s5>
</fC03>
<fC03 i1="05" i2="X" l="ENG">
<s0>Antiglaucomatous agent</s0>
<s5>25</s5>
</fC03>
<fC03 i1="05" i2="X" l="SPA">
<s0>Antiglaucomatoso</s0>
<s5>25</s5>
</fC03>
<fC03 i1="06" i2="X" l="FRE">
<s0>Traitement</s0>
<s5>26</s5>
</fC03>
<fC03 i1="06" i2="X" l="ENG">
<s0>Treatment</s0>
<s5>26</s5>
</fC03>
<fC03 i1="06" i2="X" l="SPA">
<s0>Tratamiento</s0>
<s5>26</s5>
</fC03>
<fC07 i1="01" i2="X" l="FRE">
<s0>Agoniste</s0>
<s5>37</s5>
</fC07>
<fC07 i1="01" i2="X" l="ENG">
<s0>Agonist</s0>
<s5>37</s5>
</fC07>
<fC07 i1="01" i2="X" l="SPA">
<s0>Agonista</s0>
<s5>37</s5>
</fC07>
<fC07 i1="02" i2="X" l="FRE">
<s0>Furane dérivé</s0>
<s5>38</s5>
</fC07>
<fC07 i1="02" i2="X" l="ENG">
<s0>Furan derivatives</s0>
<s5>38</s5>
</fC07>
<fC07 i1="02" i2="X" l="SPA">
<s0>Furano derivado</s0>
<s5>38</s5>
</fC07>
<fC07 i1="03" i2="X" l="FRE">
<s0>Parasympathomimétique</s0>
<s5>39</s5>
</fC07>
<fC07 i1="03" i2="X" l="ENG">
<s0>Parasympathomimetic</s0>
<s5>39</s5>
</fC07>
<fC07 i1="03" i2="X" l="SPA">
<s0>Parasimpatomimético</s0>
<s5>39</s5>
</fC07>
<fC07 i1="04" i2="X" l="FRE">
<s0>Récepteur muscarinique</s0>
<s5>40</s5>
</fC07>
<fC07 i1="04" i2="X" l="ENG">
<s0>Muscarinic receptor</s0>
<s5>40</s5>
</fC07>
<fC07 i1="04" i2="X" l="SPA">
<s0>Receptor muscarínico</s0>
<s5>40</s5>
</fC07>
<fN21>
<s1>276</s1>
</fN21>
<fN44 i1="01">
<s1>OTO</s1>
</fN44>
<fN82>
<s1>OTO</s1>
</fN82>
</pA>
</standard>
</inist>
<affiliations>
<list>
<country>
<li>Autriche</li>
</country>
<region>
<li>Vienne (Autriche)</li>
</region>
<settlement>
<li>Vienne (Autriche)</li>
</settlement>
</list>
<tree>
<country name="Autriche">
<region name="Vienne (Autriche)">
<name sortKey="Koeppl, Christina" sort="Koeppl, Christina" uniqKey="Koeppl C" first="Christina" last="Koeppl">Christina Koeppl</name>
</region>
<name sortKey="Buehl, Wolf" sort="Buehl, Wolf" uniqKey="Buehl W" first="Wolf" last="Buehl">Wolf Buehl</name>
<name sortKey="Drexler, Wolfgang" sort="Drexler, Wolfgang" uniqKey="Drexler W" first="Wolfgang" last="Drexler">Wolfgang Drexler</name>
<name sortKey="Findl, Oliver" sort="Findl, Oliver" uniqKey="Findl O" first="Oliver" last="Findl">Oliver Findl</name>
<name sortKey="Kriechbaum, Katharina" sort="Kriechbaum, Katharina" uniqKey="Kriechbaum K" first="Katharina" last="Kriechbaum">Katharina Kriechbaum</name>
<name sortKey="Menapace, Rupert" sort="Menapace, Rupert" uniqKey="Menapace R" first="Rupert" last="Menapace">Rupert Menapace</name>
<name sortKey="Sacu, Stefan" sort="Sacu, Stefan" uniqKey="Sacu S" first="Stefan" last="Sacu">Stefan Sacu</name>
<name sortKey="Wirtitsch, Matthias" sort="Wirtitsch, Matthias" uniqKey="Wirtitsch M" first="Matthias" last="Wirtitsch">Matthias Wirtitsch</name>
</country>
</tree>
</affiliations>
</record>

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