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Pilocarpine-induced shift of an accommodating intraocular lens : AT-45 Crystalens

Identifieur interne : 000E60 ( PascalFrancis/Corpus ); précédent : 000E59; suivant : 000E61

Pilocarpine-induced shift of an accommodating intraocular lens : AT-45 Crystalens

Auteurs : Christina Koeppl ; Oliver Findl ; Rupert Menapace ; Katharina Kriechbaum ; Matthias Wirtitsch ; Wolf Buehl ; Stefan Sacu ; Wolfgang Drexler

Source :

RBID : Pascal:05-0399236

Descripteurs français

English descriptors

Abstract

Purpose: To measure the shift of an accommodating plate-haptic intraocular lens (IOL) along the visual axis induced by ciliary muscle contraction after application of pilocarpine. Setting: Department of Ophthalmology, Medical University of Vienna, Vienna, Austria. Methods: Fifty-four eyes of 28 patients with age-related cataract comprised this prospective study. Each patient received an AT-45 silicone accommodating IOL (Crystalens, Eyeonics Corp.) after standardized cataract surgery. In a subgroup of 24 eyes, capsular bag fibrosis was reduced by extensive polishing of the anterior capsule with a slit cannula. Assessment included measurements of anterior chamber depth, assessed with partial coherence interferometry, before and after application of pilocarpine 2% and evaluation of near visual acuity 1 month and 3 months postoperatively. Results: A slight backward shift of the IOL of 151 μm in the nonpolished group (P<.001) and 122 μm in the polished group (P<.005) could be detected after application of pilocarpine. Polishing the capsule did not influence IOL shift. The median near visual acuity with distance correction 1 month and 3 months postoperatively was J5 and J4, respectively, in the nonpolished group and J6 at both times in the polished group. Conclusions: Pilocarpine induced a counterproductive active backward shift of the AT-45 IOL. Polishing of the capsular bag had no impact on accommodative ability. The reading performance of patients with the AT-45 IOL patients at 1 and 3 months was not significantly different from that of with a standard IOL under similar testing methods.

Notice en format standard (ISO 2709)

Pour connaître la documentation sur le format Inist Standard.

pA  
A01 01  1    @0 0886-3350
A02 01      @0 JCSUEV
A03   1    @0 J. cataract refractive surg.
A05       @2 31
A06       @2 7
A08 01  1  ENG  @1 Pilocarpine-induced shift of an accommodating intraocular lens : AT-45 Crystalens
A11 01  1    @1 KOEPPL (Christina)
A11 02  1    @1 FINDL (Oliver)
A11 03  1    @1 MENAPACE (Rupert)
A11 04  1    @1 KRIECHBAUM (Katharina)
A11 05  1    @1 WIRTITSCH (Matthias)
A11 06  1    @1 BUEHL (Wolf)
A11 07  1    @1 SACU (Stefan)
A11 08  1    @1 DREXLER (Wolfgang)
A14 01      @1 Department of Ophthalmology, Medical University of Vienna @2 Vienna @3 AUT @Z 1 aut. @Z 2 aut. @Z 3 aut. @Z 4 aut. @Z 5 aut. @Z 6 aut. @Z 7 aut.
A14 02      @1 Department of Medical Physics, University of Vienna @2 Viena @3 AUT @Z 8 aut.
A20       @1 1290-1297
A21       @1 2005
A23 01      @0 ENG
A43 01      @1 INIST @2 20937 @5 354000131572020040
A44       @0 0000 @1 © 2005 INIST-CNRS. All rights reserved.
A45       @0 38 ref.
A47 01  1    @0 05-0399236
A60       @1 P
A61       @0 A
A64 01  1    @0 Journal of cataract and refractive surgery
A66 01      @0 USA
C01 01    ENG  @0 Purpose: To measure the shift of an accommodating plate-haptic intraocular lens (IOL) along the visual axis induced by ciliary muscle contraction after application of pilocarpine. Setting: Department of Ophthalmology, Medical University of Vienna, Vienna, Austria. Methods: Fifty-four eyes of 28 patients with age-related cataract comprised this prospective study. Each patient received an AT-45 silicone accommodating IOL (Crystalens, Eyeonics Corp.) after standardized cataract surgery. In a subgroup of 24 eyes, capsular bag fibrosis was reduced by extensive polishing of the anterior capsule with a slit cannula. Assessment included measurements of anterior chamber depth, assessed with partial coherence interferometry, before and after application of pilocarpine 2% and evaluation of near visual acuity 1 month and 3 months postoperatively. Results: A slight backward shift of the IOL of 151 μm in the nonpolished group (P<.001) and 122 μm in the polished group (P<.005) could be detected after application of pilocarpine. Polishing the capsule did not influence IOL shift. The median near visual acuity with distance correction 1 month and 3 months postoperatively was J5 and J4, respectively, in the nonpolished group and J6 at both times in the polished group. Conclusions: Pilocarpine induced a counterproductive active backward shift of the AT-45 IOL. Polishing of the capsular bag had no impact on accommodative ability. The reading performance of patients with the AT-45 IOL patients at 1 and 3 months was not significantly different from that of with a standard IOL under similar testing methods.
C02 01  X    @0 002B25B
C03 01  X  FRE  @0 Pilocarpine @2 NK @2 FR @5 02
C03 01  X  ENG  @0 Pilocarpine @2 NK @2 FR @5 02
C03 01  X  SPA  @0 Pilocarpina @2 NK @2 FR @5 02
C03 02  X  FRE  @0 Lentille intraoculaire @5 03
C03 02  X  ENG  @0 Intraocular lens @5 03
C03 02  X  SPA  @0 Lente intraocular @5 03
C03 03  X  FRE  @0 Chirurgie @5 05
C03 03  X  ENG  @0 Surgery @5 05
C03 03  X  SPA  @0 Cirugía @5 05
C03 04  X  FRE  @0 Ophtalmologie @5 06
C03 04  X  ENG  @0 Ophthalmology @5 06
C03 04  X  SPA  @0 Oftalmología @5 06
C03 05  X  FRE  @0 Antiglaucomateux @5 25
C03 05  X  ENG  @0 Antiglaucomatous agent @5 25
C03 05  X  SPA  @0 Antiglaucomatoso @5 25
C03 06  X  FRE  @0 Traitement @5 26
C03 06  X  ENG  @0 Treatment @5 26
C03 06  X  SPA  @0 Tratamiento @5 26
C07 01  X  FRE  @0 Agoniste @5 37
C07 01  X  ENG  @0 Agonist @5 37
C07 01  X  SPA  @0 Agonista @5 37
C07 02  X  FRE  @0 Furane dérivé @5 38
C07 02  X  ENG  @0 Furan derivatives @5 38
C07 02  X  SPA  @0 Furano derivado @5 38
C07 03  X  FRE  @0 Parasympathomimétique @5 39
C07 03  X  ENG  @0 Parasympathomimetic @5 39
C07 03  X  SPA  @0 Parasimpatomimético @5 39
C07 04  X  FRE  @0 Récepteur muscarinique @5 40
C07 04  X  ENG  @0 Muscarinic receptor @5 40
C07 04  X  SPA  @0 Receptor muscarínico @5 40
N21       @1 276
N44 01      @1 OTO
N82       @1 OTO

Format Inist (serveur)

NO : PASCAL 05-0399236 INIST
ET : Pilocarpine-induced shift of an accommodating intraocular lens : AT-45 Crystalens
AU : KOEPPL (Christina); FINDL (Oliver); MENAPACE (Rupert); KRIECHBAUM (Katharina); WIRTITSCH (Matthias); BUEHL (Wolf); SACU (Stefan); DREXLER (Wolfgang)
AF : Department of Ophthalmology, Medical University of Vienna/Vienna/Autriche (1 aut., 2 aut., 3 aut., 4 aut., 5 aut., 6 aut., 7 aut.); Department of Medical Physics, University of Vienna/Viena/Autriche (8 aut.)
DT : Publication en série; Niveau analytique
SO : Journal of cataract and refractive surgery; ISSN 0886-3350; Coden JCSUEV; Etats-Unis; Da. 2005; Vol. 31; No. 7; Pp. 1290-1297; Bibl. 38 ref.
LA : Anglais
EA : Purpose: To measure the shift of an accommodating plate-haptic intraocular lens (IOL) along the visual axis induced by ciliary muscle contraction after application of pilocarpine. Setting: Department of Ophthalmology, Medical University of Vienna, Vienna, Austria. Methods: Fifty-four eyes of 28 patients with age-related cataract comprised this prospective study. Each patient received an AT-45 silicone accommodating IOL (Crystalens, Eyeonics Corp.) after standardized cataract surgery. In a subgroup of 24 eyes, capsular bag fibrosis was reduced by extensive polishing of the anterior capsule with a slit cannula. Assessment included measurements of anterior chamber depth, assessed with partial coherence interferometry, before and after application of pilocarpine 2% and evaluation of near visual acuity 1 month and 3 months postoperatively. Results: A slight backward shift of the IOL of 151 μm in the nonpolished group (P<.001) and 122 μm in the polished group (P<.005) could be detected after application of pilocarpine. Polishing the capsule did not influence IOL shift. The median near visual acuity with distance correction 1 month and 3 months postoperatively was J5 and J4, respectively, in the nonpolished group and J6 at both times in the polished group. Conclusions: Pilocarpine induced a counterproductive active backward shift of the AT-45 IOL. Polishing of the capsular bag had no impact on accommodative ability. The reading performance of patients with the AT-45 IOL patients at 1 and 3 months was not significantly different from that of with a standard IOL under similar testing methods.
CC : 002B25B
FD : Pilocarpine; Lentille intraoculaire; Chirurgie; Ophtalmologie; Antiglaucomateux; Traitement
FG : Agoniste; Furane dérivé; Parasympathomimétique; Récepteur muscarinique
ED : Pilocarpine; Intraocular lens; Surgery; Ophthalmology; Antiglaucomatous agent; Treatment
EG : Agonist; Furan derivatives; Parasympathomimetic; Muscarinic receptor
SD : Pilocarpina; Lente intraocular; Cirugía; Oftalmología; Antiglaucomatoso; Tratamiento
LO : INIST-20937.354000131572020040
ID : 05-0399236

Links to Exploration step

Pascal:05-0399236

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<div type="abstract" xml:lang="en">Purpose: To measure the shift of an accommodating plate-haptic intraocular lens (IOL) along the visual axis induced by ciliary muscle contraction after application of pilocarpine. Setting: Department of Ophthalmology, Medical University of Vienna, Vienna, Austria. Methods: Fifty-four eyes of 28 patients with age-related cataract comprised this prospective study. Each patient received an AT-45 silicone accommodating IOL (Crystalens, Eyeonics Corp.) after standardized cataract surgery. In a subgroup of 24 eyes, capsular bag fibrosis was reduced by extensive polishing of the anterior capsule with a slit cannula. Assessment included measurements of anterior chamber depth, assessed with partial coherence interferometry, before and after application of pilocarpine 2% and evaluation of near visual acuity 1 month and 3 months postoperatively. Results: A slight backward shift of the IOL of 151 μm in the nonpolished group (P<.001) and 122 μm in the polished group (P<.005) could be detected after application of pilocarpine. Polishing the capsule did not influence IOL shift. The median near visual acuity with distance correction 1 month and 3 months postoperatively was J5 and J4, respectively, in the nonpolished group and J6 at both times in the polished group. Conclusions: Pilocarpine induced a counterproductive active backward shift of the AT-45 IOL. Polishing of the capsular bag had no impact on accommodative ability. The reading performance of patients with the AT-45 IOL patients at 1 and 3 months was not significantly different from that of with a standard IOL under similar testing methods.</div>
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<sZ>1 aut.</sZ>
<sZ>2 aut.</sZ>
<sZ>3 aut.</sZ>
<sZ>4 aut.</sZ>
<sZ>5 aut.</sZ>
<sZ>6 aut.</sZ>
<sZ>7 aut.</sZ>
</fA14>
<fA14 i1="02">
<s1>Department of Medical Physics, University of Vienna</s1>
<s2>Viena</s2>
<s3>AUT</s3>
<sZ>8 aut.</sZ>
</fA14>
<fA20>
<s1>1290-1297</s1>
</fA20>
<fA21>
<s1>2005</s1>
</fA21>
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<s0>ENG</s0>
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<s1>INIST</s1>
<s2>20937</s2>
<s5>354000131572020040</s5>
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<s0>0000</s0>
<s1>© 2005 INIST-CNRS. All rights reserved.</s1>
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<s0>38 ref.</s0>
</fA45>
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<s0>05-0399236</s0>
</fA47>
<fA60>
<s1>P</s1>
</fA60>
<fA61>
<s0>A</s0>
</fA61>
<fA64 i1="01" i2="1">
<s0>Journal of cataract and refractive surgery</s0>
</fA64>
<fA66 i1="01">
<s0>USA</s0>
</fA66>
<fC01 i1="01" l="ENG">
<s0>Purpose: To measure the shift of an accommodating plate-haptic intraocular lens (IOL) along the visual axis induced by ciliary muscle contraction after application of pilocarpine. Setting: Department of Ophthalmology, Medical University of Vienna, Vienna, Austria. Methods: Fifty-four eyes of 28 patients with age-related cataract comprised this prospective study. Each patient received an AT-45 silicone accommodating IOL (Crystalens, Eyeonics Corp.) after standardized cataract surgery. In a subgroup of 24 eyes, capsular bag fibrosis was reduced by extensive polishing of the anterior capsule with a slit cannula. Assessment included measurements of anterior chamber depth, assessed with partial coherence interferometry, before and after application of pilocarpine 2% and evaluation of near visual acuity 1 month and 3 months postoperatively. Results: A slight backward shift of the IOL of 151 μm in the nonpolished group (P<.001) and 122 μm in the polished group (P<.005) could be detected after application of pilocarpine. Polishing the capsule did not influence IOL shift. The median near visual acuity with distance correction 1 month and 3 months postoperatively was J5 and J4, respectively, in the nonpolished group and J6 at both times in the polished group. Conclusions: Pilocarpine induced a counterproductive active backward shift of the AT-45 IOL. Polishing of the capsular bag had no impact on accommodative ability. The reading performance of patients with the AT-45 IOL patients at 1 and 3 months was not significantly different from that of with a standard IOL under similar testing methods.</s0>
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<s0>002B25B</s0>
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<s0>Pilocarpine</s0>
<s2>NK</s2>
<s2>FR</s2>
<s5>02</s5>
</fC03>
<fC03 i1="01" i2="X" l="ENG">
<s0>Pilocarpine</s0>
<s2>NK</s2>
<s2>FR</s2>
<s5>02</s5>
</fC03>
<fC03 i1="01" i2="X" l="SPA">
<s0>Pilocarpina</s0>
<s2>NK</s2>
<s2>FR</s2>
<s5>02</s5>
</fC03>
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<s0>Lentille intraoculaire</s0>
<s5>03</s5>
</fC03>
<fC03 i1="02" i2="X" l="ENG">
<s0>Intraocular lens</s0>
<s5>03</s5>
</fC03>
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<s0>Lente intraocular</s0>
<s5>03</s5>
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<s0>Chirurgie</s0>
<s5>05</s5>
</fC03>
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<s0>Surgery</s0>
<s5>05</s5>
</fC03>
<fC03 i1="03" i2="X" l="SPA">
<s0>Cirugía</s0>
<s5>05</s5>
</fC03>
<fC03 i1="04" i2="X" l="FRE">
<s0>Ophtalmologie</s0>
<s5>06</s5>
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<s5>06</s5>
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<s5>06</s5>
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<s5>25</s5>
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<s5>25</s5>
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<s0>Traitement</s0>
<s5>26</s5>
</fC03>
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<s0>Treatment</s0>
<s5>26</s5>
</fC03>
<fC03 i1="06" i2="X" l="SPA">
<s0>Tratamiento</s0>
<s5>26</s5>
</fC03>
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<s5>37</s5>
</fC07>
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<s5>37</s5>
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<s5>37</s5>
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<s5>38</s5>
</fC07>
<fC07 i1="02" i2="X" l="ENG">
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<s5>38</s5>
</fC07>
<fC07 i1="02" i2="X" l="SPA">
<s0>Furano derivado</s0>
<s5>38</s5>
</fC07>
<fC07 i1="03" i2="X" l="FRE">
<s0>Parasympathomimétique</s0>
<s5>39</s5>
</fC07>
<fC07 i1="03" i2="X" l="ENG">
<s0>Parasympathomimetic</s0>
<s5>39</s5>
</fC07>
<fC07 i1="03" i2="X" l="SPA">
<s0>Parasimpatomimético</s0>
<s5>39</s5>
</fC07>
<fC07 i1="04" i2="X" l="FRE">
<s0>Récepteur muscarinique</s0>
<s5>40</s5>
</fC07>
<fC07 i1="04" i2="X" l="ENG">
<s0>Muscarinic receptor</s0>
<s5>40</s5>
</fC07>
<fC07 i1="04" i2="X" l="SPA">
<s0>Receptor muscarínico</s0>
<s5>40</s5>
</fC07>
<fN21>
<s1>276</s1>
</fN21>
<fN44 i1="01">
<s1>OTO</s1>
</fN44>
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<s1>OTO</s1>
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<server>
<NO>PASCAL 05-0399236 INIST</NO>
<ET>Pilocarpine-induced shift of an accommodating intraocular lens : AT-45 Crystalens</ET>
<AU>KOEPPL (Christina); FINDL (Oliver); MENAPACE (Rupert); KRIECHBAUM (Katharina); WIRTITSCH (Matthias); BUEHL (Wolf); SACU (Stefan); DREXLER (Wolfgang)</AU>
<AF>Department of Ophthalmology, Medical University of Vienna/Vienna/Autriche (1 aut., 2 aut., 3 aut., 4 aut., 5 aut., 6 aut., 7 aut.); Department of Medical Physics, University of Vienna/Viena/Autriche (8 aut.)</AF>
<DT>Publication en série; Niveau analytique</DT>
<SO>Journal of cataract and refractive surgery; ISSN 0886-3350; Coden JCSUEV; Etats-Unis; Da. 2005; Vol. 31; No. 7; Pp. 1290-1297; Bibl. 38 ref.</SO>
<LA>Anglais</LA>
<EA>Purpose: To measure the shift of an accommodating plate-haptic intraocular lens (IOL) along the visual axis induced by ciliary muscle contraction after application of pilocarpine. Setting: Department of Ophthalmology, Medical University of Vienna, Vienna, Austria. Methods: Fifty-four eyes of 28 patients with age-related cataract comprised this prospective study. Each patient received an AT-45 silicone accommodating IOL (Crystalens, Eyeonics Corp.) after standardized cataract surgery. In a subgroup of 24 eyes, capsular bag fibrosis was reduced by extensive polishing of the anterior capsule with a slit cannula. Assessment included measurements of anterior chamber depth, assessed with partial coherence interferometry, before and after application of pilocarpine 2% and evaluation of near visual acuity 1 month and 3 months postoperatively. Results: A slight backward shift of the IOL of 151 μm in the nonpolished group (P<.001) and 122 μm in the polished group (P<.005) could be detected after application of pilocarpine. Polishing the capsule did not influence IOL shift. The median near visual acuity with distance correction 1 month and 3 months postoperatively was J5 and J4, respectively, in the nonpolished group and J6 at both times in the polished group. Conclusions: Pilocarpine induced a counterproductive active backward shift of the AT-45 IOL. Polishing of the capsular bag had no impact on accommodative ability. The reading performance of patients with the AT-45 IOL patients at 1 and 3 months was not significantly different from that of with a standard IOL under similar testing methods.</EA>
<CC>002B25B</CC>
<FD>Pilocarpine; Lentille intraoculaire; Chirurgie; Ophtalmologie; Antiglaucomateux; Traitement</FD>
<FG>Agoniste; Furane dérivé; Parasympathomimétique; Récepteur muscarinique</FG>
<ED>Pilocarpine; Intraocular lens; Surgery; Ophthalmology; Antiglaucomatous agent; Treatment</ED>
<EG>Agonist; Furan derivatives; Parasympathomimetic; Muscarinic receptor</EG>
<SD>Pilocarpina; Lente intraocular; Cirugía; Oftalmología; Antiglaucomatoso; Tratamiento</SD>
<LO>INIST-20937.354000131572020040</LO>
<ID>05-0399236</ID>
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