HapticV1, Main, Exploration, bibRecordById, pubmed:16105597

Pilocarpine-induced shift of an accommodating intraocular lens : AT-45 Crystalens

Identifieur interne : 006569 ( Main/Exploration ); précédent : 006568; suivant : 006570

Pilocarpine-induced shift of an accommodating intraocular lens : AT-45 Crystalens

Auteurs : Christina Koeppl [Autriche] ; Oliver Findl [Autriche] ; Rupert Menapace [Autriche] ; Katharina Kriechbaum [Autriche] ; Matthias Wirtitsch [Autriche] ; Wolf Buehl [Autriche] ; Stefan Sacu [Autriche] ; Wolfgang Drexler [Autriche]

Source :

Journal of cataract and refractive surgery [ 0886-3350 ] ; 2005.

RBID : Pascal:05-0399236

Descripteurs français

Pascal (Inist)
- Pilocarpine, Lentille intraoculaire, Chirurgie, Ophtalmologie, Antiglaucomateux, Traitement.
Wicri :
- topic : Chirurgie.

English descriptors

KwdEn :
- Accommodation, Ocular (drug effects), Aged, Aged, 80 and over, Antiglaucomatous agent, Ciliary Body (drug effects), Foreign-Body Migration (etiology), Humans, Intraocular lens, Lens Implantation, Intraocular, Lenses, Intraocular, Middle Aged, Miotics (adverse effects), Muscle Contraction (drug effects), Muscle, Smooth (drug effects), Ophthalmology, Phacoemulsification, Pilocarpine, Pilocarpine (adverse effects), Prospective Studies, Prosthesis Design, Surgery, Treatment.
MESH :
- chemical , adverse effects : Miotics, Pilocarpine.
- drug effects : Accommodation, Ocular, Ciliary Body, Muscle Contraction, Muscle, Smooth.
- etiology : Foreign-Body Migration.
- Aged, Aged, 80 and over, Humans, Lens Implantation, Intraocular, Lenses, Intraocular, Middle Aged, Phacoemulsification, Prospective Studies, Prosthesis Design.

Abstract

Purpose: To measure the shift of an accommodating plate-haptic intraocular lens (IOL) along the visual axis induced by ciliary muscle contraction after application of pilocarpine. Setting: Department of Ophthalmology, Medical University of Vienna, Vienna, Austria. Methods: Fifty-four eyes of 28 patients with age-related cataract comprised this prospective study. Each patient received an AT-45 silicone accommodating IOL (Crystalens, Eyeonics Corp.) after standardized cataract surgery. In a subgroup of 24 eyes, capsular bag fibrosis was reduced by extensive polishing of the anterior capsule with a slit cannula. Assessment included measurements of anterior chamber depth, assessed with partial coherence interferometry, before and after application of pilocarpine 2% and evaluation of near visual acuity 1 month and 3 months postoperatively. Results: A slight backward shift of the IOL of 151 μm in the nonpolished group (P<.001) and 122 μm in the polished group (P<.005) could be detected after application of pilocarpine. Polishing the capsule did not influence IOL shift. The median near visual acuity with distance correction 1 month and 3 months postoperatively was J5 and J4, respectively, in the nonpolished group and J6 at both times in the polished group. Conclusions: Pilocarpine induced a counterproductive active backward shift of the AT-45 IOL. Polishing of the capsular bag had no impact on accommodative ability. The reading performance of patients with the AT-45 IOL patients at 1 and 3 months was not significantly different from that of with a standard IOL under similar testing methods.

Affiliations:

Le document en format XML

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<profileDesc><textClass><keywords scheme="KwdEn" xml:lang="en"><term>Accommodation, Ocular (drug effects)</term>
<term>Aged</term>
<term>Aged, 80 and over</term>
<term>Antiglaucomatous agent</term>
<term>Ciliary Body (drug effects)</term>
<term>Foreign-Body Migration (etiology)</term>
<term>Humans</term>
<term>Intraocular lens</term>
<term>Lens Implantation, Intraocular</term>
<term>Lenses, Intraocular</term>
<term>Middle Aged</term>
<term>Miotics (adverse effects)</term>
<term>Muscle Contraction (drug effects)</term>
<term>Muscle, Smooth (drug effects)</term>
<term>Ophthalmology</term>
<term>Phacoemulsification</term>
<term>Pilocarpine</term>
<term>Pilocarpine (adverse effects)</term>
<term>Prospective Studies</term>
<term>Prosthesis Design</term>
<term>Surgery</term>
<term>Treatment</term>
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<keywords scheme="MESH" type="chemical" qualifier="adverse effects" xml:lang="en"><term>Miotics</term>
<term>Pilocarpine</term>
</keywords>
<keywords scheme="MESH" qualifier="drug effects" xml:lang="en"><term>Accommodation, Ocular</term>
<term>Ciliary Body</term>
<term>Muscle Contraction</term>
<term>Muscle, Smooth</term>
</keywords>
<keywords scheme="MESH" qualifier="etiology" xml:lang="en"><term>Foreign-Body Migration</term>
</keywords>
<keywords scheme="MESH" xml:lang="en"><term>Aged</term>
<term>Aged, 80 and over</term>
<term>Humans</term>
<term>Lens Implantation, Intraocular</term>
<term>Lenses, Intraocular</term>
<term>Middle Aged</term>
<term>Phacoemulsification</term>
<term>Prospective Studies</term>
<term>Prosthesis Design</term>
</keywords>
<keywords scheme="Pascal" xml:lang="fr"><term>Pilocarpine</term>
<term>Lentille intraoculaire</term>
<term>Chirurgie</term>
<term>Ophtalmologie</term>
<term>Antiglaucomateux</term>
<term>Traitement</term>
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<front><div type="abstract" xml:lang="en">Purpose: To measure the shift of an accommodating plate-haptic intraocular lens (IOL) along the visual axis induced by ciliary muscle contraction after application of pilocarpine. Setting: Department of Ophthalmology, Medical University of Vienna, Vienna, Austria. Methods: Fifty-four eyes of 28 patients with age-related cataract comprised this prospective study. Each patient received an AT-45 silicone accommodating IOL (Crystalens, Eyeonics Corp.) after standardized cataract surgery. In a subgroup of 24 eyes, capsular bag fibrosis was reduced by extensive polishing of the anterior capsule with a slit cannula. Assessment included measurements of anterior chamber depth, assessed with partial coherence interferometry, before and after application of pilocarpine 2% and evaluation of near visual acuity 1 month and 3 months postoperatively. Results: A slight backward shift of the IOL of 151 μm in the nonpolished group (P<.001) and 122 μm in the polished group (P<.005) could be detected after application of pilocarpine. Polishing the capsule did not influence IOL shift. The median near visual acuity with distance correction 1 month and 3 months postoperatively was J5 and J4, respectively, in the nonpolished group and J6 at both times in the polished group. Conclusions: Pilocarpine induced a counterproductive active backward shift of the AT-45 IOL. Polishing of the capsular bag had no impact on accommodative ability. The reading performance of patients with the AT-45 IOL patients at 1 and 3 months was not significantly different from that of with a standard IOL under similar testing methods.</div>
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<affiliations><list><country><li>Autriche</li>
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<region><li>Vienne (Autriche)</li>
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<name sortKey="Buehl, Wolf" sort="Buehl, Wolf" uniqKey="Buehl W" first="Wolf" last="Buehl">Wolf Buehl</name>
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<name sortKey="Findl, Oliver" sort="Findl, Oliver" uniqKey="Findl O" first="Oliver" last="Findl">Oliver Findl</name>
<name sortKey="Kriechbaum, Katharina" sort="Kriechbaum, Katharina" uniqKey="Kriechbaum K" first="Katharina" last="Kriechbaum">Katharina Kriechbaum</name>
<name sortKey="Menapace, Rupert" sort="Menapace, Rupert" uniqKey="Menapace R" first="Rupert" last="Menapace">Rupert Menapace</name>
<name sortKey="Sacu, Stefan" sort="Sacu, Stefan" uniqKey="Sacu S" first="Stefan" last="Sacu">Stefan Sacu</name>
<name sortKey="Wirtitsch, Matthias" sort="Wirtitsch, Matthias" uniqKey="Wirtitsch M" first="Matthias" last="Wirtitsch">Matthias Wirtitsch</name>
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Pilocarpine-induced shift of an accommodating intraocular lens : AT-45 Crystalens

Pilocarpine-induced shift of an accommodating intraocular lens : AT-45 Crystalens

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