Psychosocial and Immunological Factors in Neurasthenia
Identifieur interne : 001C59 ( Main/Exploration ); précédent : 001C58; suivant : 001C60Psychosocial and Immunological Factors in Neurasthenia
Auteurs : YUPING CAO [République populaire de Chine, États-Unis] ; YALIN ZHANG ; Doris F. Chang ; GUOQIANG WANG ; XIANGHUI ZHANGSource :
- Psychosomatics : (Washington, DC) [ 0033-3182 ] ; 2009.
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- Pascal (Inist)
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- topic : Homme.
English descriptors
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Abstract
Background: Neurasthenia is a disorder whose pathogenesis is still unknown. Objective: The authors sought to examine the relationships between neurasthenia and possible psychosocial and immunological correlates. Method: A sample of 30 Chinese neurasthenic patients was compared with a matched sample of 30 control subjects for 1) the level of serum Epstein-Barr virus (EBV) gamma G immunoglobulin (IgG) and gamma M immunoglobulin (IgM); 2) scores on the Eysenck Personality Questionnaire (EPQ); 3) the Symptom Checklist-90; and 4) the Life Event Scale (LES); 27 of the 30 neurasthenia patients were treated with medication and psychotherapy for a 4-month period, with measures taken pre- and posttreatment. Results: As compared with the control group, neurasthenic patients exhibited higher EPQ scores for neuroticism, higher levels of introversion, and a higher number of negative life events. Within the neurasthenia sample, scores for neuroticism and the SCL-90 Global Severity Index were significantly lower at follow-up than at baseline. Conclusion: As compared with control subjects, neurasthenia patients were characterized by greater neuroticism and introversion, and they reported a higher rate of negative life events. Moreover, the positive rate of EBV in neurasthenic patients was higher, which may be associated with higher EBV activation under states of stress.
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Chang</name></author><author><name sortKey="Guoqiang Wang" sort="Guoqiang Wang" uniqKey="Guoqiang Wang" last="Guoqiang Wang">GUOQIANG WANG</name></author><author><name sortKey="Xianghui Zhang" sort="Xianghui Zhang" uniqKey="Xianghui Zhang" last="Xianghui Zhang">XIANGHUI ZHANG</name></author></titleStmt><publicationStmt><idno type="wicri:source">INIST</idno><idno type="inist">09-0192534</idno><date when="2009">2009</date><idno type="stanalyst">PASCAL 09-0192534 INIST</idno><idno type="RBID">Pascal:09-0192534</idno><idno type="wicri:Area/PascalFrancis/Corpus">000141</idno><idno type="stanalyst">FRANCIS 09-0192534 INIST</idno><idno type="wicri:Area/PascalFrancis/Corpus">000155</idno><idno type="wicri:Area/PascalFrancis/Curation">000138</idno><idno type="wicri:Area/PascalFrancis/Checkpoint">000082</idno><idno type="wicri:explorRef" wicri:stream="PascalFrancis" wicri:step="Checkpoint">000082</idno><idno type="wicri:doubleKey">0033-3182:2009:Yuping Cao:psychosocial:and:immunological</idno><idno type="wicri:Area/Main/Merge">001C61</idno><idno type="wicri:Area/Main/Curation">001C59</idno><idno type="wicri:Area/Main/Exploration">001C59</idno></publicationStmt><sourceDesc><biblStruct><analytic><title xml:lang="en" level="a">Psychosocial and Immunological Factors in Neurasthenia</title><author><name sortKey="Yuping Cao" sort="Yuping Cao" uniqKey="Yuping Cao" last="Yuping Cao">YUPING CAO</name><affiliation wicri:level="1"><inist:fA14 i1="01"><s1>Mental Health Institute, Second Xiangya Hospital, Central South University</s1><s2>Changsha, Hunan</s2><s3>CHN</s3></inist:fA14><country>République populaire de Chine</country><wicri:noRegion>Changsha, Hunan</wicri:noRegion></affiliation><affiliation wicri:level="2"><inist:fA14 i1="02"><s1>Dept. of Psychology, New School for Social Research</s1><s2>New York, NY</s2><s3>USA</s3></inist:fA14><country>États-Unis</country><placeName><region type="state">État de New York</region></placeName></affiliation></author><author><name sortKey="Yalin Zhang" sort="Yalin Zhang" uniqKey="Yalin Zhang" last="Yalin Zhang">YALIN ZHANG</name></author><author><name sortKey="Chang, Doris F" sort="Chang, Doris F" uniqKey="Chang D" first="Doris F." last="Chang">Doris F. Chang</name></author><author><name sortKey="Guoqiang Wang" sort="Guoqiang Wang" uniqKey="Guoqiang Wang" last="Guoqiang Wang">GUOQIANG WANG</name></author><author><name sortKey="Xianghui Zhang" sort="Xianghui Zhang" uniqKey="Xianghui Zhang" last="Xianghui Zhang">XIANGHUI ZHANG</name></author></analytic><series><title level="j" type="main">Psychosomatics : (Washington, DC)</title><title level="j" type="abbreviated">Psychosomatics : (Wash. DC)</title><idno type="ISSN">0033-3182</idno><imprint><date when="2009">2009</date></imprint></series></biblStruct></sourceDesc><seriesStmt><title level="j" type="main">Psychosomatics : (Washington, DC)</title><title level="j" type="abbreviated">Psychosomatics : (Wash. DC)</title><idno type="ISSN">0033-3182</idno></seriesStmt></fileDesc><profileDesc><textClass><keywords scheme="KwdEn" xml:lang="en"><term>China</term><term>Epstein Barr virus</term><term>Extraversion introversion</term><term>Human</term><term>Life events</term><term>Neurasthenia</term><term>Neuroticism</term><term>Psychosocial factor</term><term>Social environment</term><term>Stress</term></keywords><keywords scheme="Pascal" xml:lang="fr"><term>Facteur psychosocial</term><term>Neurasthénie</term><term>Névrotisme</term><term>Extraversion introversion</term><term>Evénement existentiel</term><term>Virus Epstein Barr</term><term>Stress</term><term>Environnement social</term><term>Chine</term><term>Homme</term></keywords><keywords scheme="Wicri" type="topic" xml:lang="fr"><term>Homme</term></keywords></textClass></profileDesc></teiHeader><front><div type="abstract" xml:lang="en">Background: Neurasthenia is a disorder whose pathogenesis is still unknown. Objective: The authors sought to examine the relationships between neurasthenia and possible psychosocial and immunological correlates. Method: A sample of 30 Chinese neurasthenic patients was compared with a matched sample of 30 control subjects for 1) the level of serum Epstein-Barr virus (EBV) gamma G immunoglobulin (IgG) and gamma M immunoglobulin (IgM); 2) scores on the Eysenck Personality Questionnaire (EPQ); 3) the Symptom Checklist-90; and 4) the Life Event Scale (LES); 27 of the 30 neurasthenia patients were treated with medication and psychotherapy for a 4-month period, with measures taken pre- and posttreatment. Results: As compared with the control group, neurasthenic patients exhibited higher EPQ scores for neuroticism, higher levels of introversion, and a higher number of negative life events. Within the neurasthenia sample, scores for neuroticism and the SCL-90 Global Severity Index were significantly lower at follow-up than at baseline. Conclusion: As compared with control subjects, neurasthenia patients were characterized by greater neuroticism and introversion, and they reported a higher rate of negative life events. Moreover, the positive rate of EBV in neurasthenic patients was higher, which may be associated with higher EBV activation under states of stress.</div></front></TEI><affiliations><list><country><li>République populaire de Chine</li><li>États-Unis</li></country><region><li>État de New York</li></region></list><tree><noCountry><name sortKey="Chang, Doris F" sort="Chang, Doris F" uniqKey="Chang D" first="Doris F." last="Chang">Doris F. Chang</name><name sortKey="Guoqiang Wang" sort="Guoqiang Wang" uniqKey="Guoqiang Wang" last="Guoqiang Wang">GUOQIANG WANG</name><name sortKey="Xianghui Zhang" sort="Xianghui Zhang" uniqKey="Xianghui Zhang" last="Xianghui Zhang">XIANGHUI ZHANG</name><name sortKey="Yalin Zhang" sort="Yalin Zhang" uniqKey="Yalin Zhang" last="Yalin Zhang">YALIN ZHANG</name></noCountry><country name="République populaire de Chine"><noRegion><name sortKey="Yuping Cao" sort="Yuping Cao" uniqKey="Yuping Cao" last="Yuping Cao">YUPING CAO</name></noRegion></country><country name="États-Unis"><region name="État de New York"><name sortKey="Yuping Cao" sort="Yuping Cao" uniqKey="Yuping Cao" last="Yuping Cao">YUPING CAO</name></region></country></tree></affiliations></record>Pour manipuler ce document sous Unix (Dilib)
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