Psychosocial and Immunological Factors in Neurasthenia
Identifieur interne : 000082 ( PascalFrancis/Checkpoint ); précédent : 000081; suivant : 000083Psychosocial and Immunological Factors in Neurasthenia
Auteurs : YUPING CAO [République populaire de Chine, États-Unis] ; YALIN ZHANG ; Doris F. Chang ; GUOQIANG WANG ; XIANGHUI ZHANGSource :
- Psychosomatics : (Washington, DC) [ 0033-3182 ] ; 2009.
Descripteurs français
- Pascal (Inist)
- Wicri :
- topic : Homme.
English descriptors
- KwdEn :
Abstract
Background: Neurasthenia is a disorder whose pathogenesis is still unknown. Objective: The authors sought to examine the relationships between neurasthenia and possible psychosocial and immunological correlates. Method: A sample of 30 Chinese neurasthenic patients was compared with a matched sample of 30 control subjects for 1) the level of serum Epstein-Barr virus (EBV) gamma G immunoglobulin (IgG) and gamma M immunoglobulin (IgM); 2) scores on the Eysenck Personality Questionnaire (EPQ); 3) the Symptom Checklist-90; and 4) the Life Event Scale (LES); 27 of the 30 neurasthenia patients were treated with medication and psychotherapy for a 4-month period, with measures taken pre- and posttreatment. Results: As compared with the control group, neurasthenic patients exhibited higher EPQ scores for neuroticism, higher levels of introversion, and a higher number of negative life events. Within the neurasthenia sample, scores for neuroticism and the SCL-90 Global Severity Index were significantly lower at follow-up than at baseline. Conclusion: As compared with control subjects, neurasthenia patients were characterized by greater neuroticism and introversion, and they reported a higher rate of negative life events. Moreover, the positive rate of EBV in neurasthenic patients was higher, which may be associated with higher EBV activation under states of stress.
Affiliations:
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<affiliation wicri:level="2"><inist:fA14 i1="02"><s1>Dept. of Psychology, New School for Social Research</s1>
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<author><name sortKey="Yalin Zhang" sort="Yalin Zhang" uniqKey="Yalin Zhang" last="Yalin Zhang">YALIN ZHANG</name>
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<author><name sortKey="Chang, Doris F" sort="Chang, Doris F" uniqKey="Chang D" first="Doris F." last="Chang">Doris F. Chang</name>
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<profileDesc><textClass><keywords scheme="KwdEn" xml:lang="en"><term>China</term>
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<term>Neurasthenia</term>
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<keywords scheme="Pascal" xml:lang="fr"><term>Facteur psychosocial</term>
<term>Neurasthénie</term>
<term>Névrotisme</term>
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<term>Evénement existentiel</term>
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<front><div type="abstract" xml:lang="en">Background: Neurasthenia is a disorder whose pathogenesis is still unknown. Objective: The authors sought to examine the relationships between neurasthenia and possible psychosocial and immunological correlates. Method: A sample of 30 Chinese neurasthenic patients was compared with a matched sample of 30 control subjects for 1) the level of serum Epstein-Barr virus (EBV) gamma G immunoglobulin (IgG) and gamma M immunoglobulin (IgM); 2) scores on the Eysenck Personality Questionnaire (EPQ); 3) the Symptom Checklist-90; and 4) the Life Event Scale (LES); 27 of the 30 neurasthenia patients were treated with medication and psychotherapy for a 4-month period, with measures taken pre- and posttreatment. Results: As compared with the control group, neurasthenic patients exhibited higher EPQ scores for neuroticism, higher levels of introversion, and a higher number of negative life events. Within the neurasthenia sample, scores for neuroticism and the SCL-90 Global Severity Index were significantly lower at follow-up than at baseline. Conclusion: As compared with control subjects, neurasthenia patients were characterized by greater neuroticism and introversion, and they reported a higher rate of negative life events. Moreover, the positive rate of EBV in neurasthenic patients was higher, which may be associated with higher EBV activation under states of stress.</div>
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