A throat lozenge containing amyl meta cresol and dichlorobenzyl alcohol has a direct virucidal effect on respiratory syncytial virus, influenza A and SARS-CoV
Identifieur interne : 000716 ( PascalFrancis/Checkpoint ); précédent : 000715; suivant : 000717A throat lozenge containing amyl meta cresol and dichlorobenzyl alcohol has a direct virucidal effect on respiratory syncytial virus, influenza A and SARS-CoV
Auteurs : John S. Oxford [Royaume-Uni] ; Robert Lambkin [Royaume-Uni] ; Iain Gibb [Royaume-Uni] ; Shobana Balasingam [Royaume-Uni] ; Charlotte Chan [Royaume-Uni] ; Andrew Catchpole [Royaume-Uni]Source :
- Antiviral chemistry & chemotherapy [ 0956-3202 ] ; 2005.
Descripteurs français
- Pascal (Inist)
- Wicri :
- topic : Alcool.
English descriptors
- KwdEn :
Abstract
A potent virucidal mixture containing amyl metacresol and dichlorobenzyl alcohol at low pH inactivated enveloped respiratory viruses influenza A, respiratory synctial virus (RSV) and severe acute respiratory syndrome coronavirus (SARS-CoV) but not viruses with icosahedral symmetry, such as adenoviruses or rhinoviruses. A titre of approximately 3.5 log10 TCID50 was reduced to below the level of detection within two minutes. Electron microscopy of purified influenza A virus showed extensive clumping and morphological changes in spike configuration after contact with the virucidal mixture, but no overt destruction of the viral membrane. We conclude that, formulated as a lozenge, the mixture could have significant effects in reducing the infectivity of certain infectious viruses in the throat and presumably in cough droplets, thus reducing, theoretically, opportunities for person-to-person transmission.
Affiliations:
Links toward previous steps (curation, corpus...)
Links to Exploration step
Pascal:05-0281109Le document en format XML
<record><TEI><teiHeader><fileDesc><titleStmt><title xml:lang="en" level="a">A throat lozenge containing amyl meta cresol and dichlorobenzyl alcohol has a direct virucidal effect on respiratory syncytial virus, influenza A and SARS-CoV</title>
<author><name sortKey="Oxford, John S" sort="Oxford, John S" uniqKey="Oxford J" first="John S." last="Oxford">John S. Oxford</name>
<affiliation wicri:level="3"><inist:fA14 i1="01"><s1>Retroscreen Virology Ltd, Institute of Cell & Molecular Sciences, Barts & the Royal London, Queen Mary's School of Medicine and Dentistry</s1>
<s2>London</s2>
<s3>GBR</s3>
<sZ>1 aut.</sZ>
<sZ>2 aut.</sZ>
<sZ>4 aut.</sZ>
<sZ>5 aut.</sZ>
<sZ>6 aut.</sZ>
</inist:fA14>
<country>Royaume-Uni</country>
<placeName><settlement type="city">Londres</settlement>
<region type="country">Angleterre</region>
<region type="région" nuts="1">Grand Londres</region>
</placeName>
</affiliation>
</author>
<author><name sortKey="Lambkin, Robert" sort="Lambkin, Robert" uniqKey="Lambkin R" first="Robert" last="Lambkin">Robert Lambkin</name>
<affiliation wicri:level="3"><inist:fA14 i1="01"><s1>Retroscreen Virology Ltd, Institute of Cell & Molecular Sciences, Barts & the Royal London, Queen Mary's School of Medicine and Dentistry</s1>
<s2>London</s2>
<s3>GBR</s3>
<sZ>1 aut.</sZ>
<sZ>2 aut.</sZ>
<sZ>4 aut.</sZ>
<sZ>5 aut.</sZ>
<sZ>6 aut.</sZ>
</inist:fA14>
<country>Royaume-Uni</country>
<placeName><settlement type="city">Londres</settlement>
<region type="country">Angleterre</region>
<region type="région" nuts="1">Grand Londres</region>
</placeName>
</affiliation>
</author>
<author><name sortKey="Gibb, Iain" sort="Gibb, Iain" uniqKey="Gibb I" first="Iain" last="Gibb">Iain Gibb</name>
<affiliation wicri:level="1"><inist:fA14 i1="02"><s1>Boots Healthcare International Ltd, Product Development (Healthcare)</s1>
<s2>Nottingham</s2>
<s3>GBR</s3>
<sZ>3 aut.</sZ>
</inist:fA14>
<country>Royaume-Uni</country>
<wicri:noRegion>Nottingham</wicri:noRegion>
</affiliation>
</author>
<author><name sortKey="Balasingam, Shobana" sort="Balasingam, Shobana" uniqKey="Balasingam S" first="Shobana" last="Balasingam">Shobana Balasingam</name>
<affiliation wicri:level="3"><inist:fA14 i1="01"><s1>Retroscreen Virology Ltd, Institute of Cell & Molecular Sciences, Barts & the Royal London, Queen Mary's School of Medicine and Dentistry</s1>
<s2>London</s2>
<s3>GBR</s3>
<sZ>1 aut.</sZ>
<sZ>2 aut.</sZ>
<sZ>4 aut.</sZ>
<sZ>5 aut.</sZ>
<sZ>6 aut.</sZ>
</inist:fA14>
<country>Royaume-Uni</country>
<placeName><settlement type="city">Londres</settlement>
<region type="country">Angleterre</region>
<region type="région" nuts="1">Grand Londres</region>
</placeName>
</affiliation>
</author>
<author><name sortKey="Chan, Charlotte" sort="Chan, Charlotte" uniqKey="Chan C" first="Charlotte" last="Chan">Charlotte Chan</name>
<affiliation wicri:level="3"><inist:fA14 i1="01"><s1>Retroscreen Virology Ltd, Institute of Cell & Molecular Sciences, Barts & the Royal London, Queen Mary's School of Medicine and Dentistry</s1>
<s2>London</s2>
<s3>GBR</s3>
<sZ>1 aut.</sZ>
<sZ>2 aut.</sZ>
<sZ>4 aut.</sZ>
<sZ>5 aut.</sZ>
<sZ>6 aut.</sZ>
</inist:fA14>
<country>Royaume-Uni</country>
<placeName><settlement type="city">Londres</settlement>
<region type="country">Angleterre</region>
<region type="région" nuts="1">Grand Londres</region>
</placeName>
</affiliation>
</author>
<author><name sortKey="Catchpole, Andrew" sort="Catchpole, Andrew" uniqKey="Catchpole A" first="Andrew" last="Catchpole">Andrew Catchpole</name>
<affiliation wicri:level="3"><inist:fA14 i1="01"><s1>Retroscreen Virology Ltd, Institute of Cell & Molecular Sciences, Barts & the Royal London, Queen Mary's School of Medicine and Dentistry</s1>
<s2>London</s2>
<s3>GBR</s3>
<sZ>1 aut.</sZ>
<sZ>2 aut.</sZ>
<sZ>4 aut.</sZ>
<sZ>5 aut.</sZ>
<sZ>6 aut.</sZ>
</inist:fA14>
<country>Royaume-Uni</country>
<placeName><settlement type="city">Londres</settlement>
<region type="country">Angleterre</region>
<region type="région" nuts="1">Grand Londres</region>
</placeName>
</affiliation>
</author>
</titleStmt>
<publicationStmt><idno type="wicri:source">INIST</idno>
<idno type="inist">05-0281109</idno>
<date when="2005">2005</date>
<idno type="stanalyst">PASCAL 05-0281109 INIST</idno>
<idno type="RBID">Pascal:05-0281109</idno>
<idno type="wicri:Area/PascalFrancis/Corpus">000657</idno>
<idno type="wicri:Area/PascalFrancis/Curation">000333</idno>
<idno type="wicri:Area/PascalFrancis/Checkpoint">000716</idno>
<idno type="wicri:explorRef" wicri:stream="PascalFrancis" wicri:step="Checkpoint">000716</idno>
</publicationStmt>
<sourceDesc><biblStruct><analytic><title xml:lang="en" level="a">A throat lozenge containing amyl meta cresol and dichlorobenzyl alcohol has a direct virucidal effect on respiratory syncytial virus, influenza A and SARS-CoV</title>
<author><name sortKey="Oxford, John S" sort="Oxford, John S" uniqKey="Oxford J" first="John S." last="Oxford">John S. Oxford</name>
<affiliation wicri:level="3"><inist:fA14 i1="01"><s1>Retroscreen Virology Ltd, Institute of Cell & Molecular Sciences, Barts & the Royal London, Queen Mary's School of Medicine and Dentistry</s1>
<s2>London</s2>
<s3>GBR</s3>
<sZ>1 aut.</sZ>
<sZ>2 aut.</sZ>
<sZ>4 aut.</sZ>
<sZ>5 aut.</sZ>
<sZ>6 aut.</sZ>
</inist:fA14>
<country>Royaume-Uni</country>
<placeName><settlement type="city">Londres</settlement>
<region type="country">Angleterre</region>
<region type="région" nuts="1">Grand Londres</region>
</placeName>
</affiliation>
</author>
<author><name sortKey="Lambkin, Robert" sort="Lambkin, Robert" uniqKey="Lambkin R" first="Robert" last="Lambkin">Robert Lambkin</name>
<affiliation wicri:level="3"><inist:fA14 i1="01"><s1>Retroscreen Virology Ltd, Institute of Cell & Molecular Sciences, Barts & the Royal London, Queen Mary's School of Medicine and Dentistry</s1>
<s2>London</s2>
<s3>GBR</s3>
<sZ>1 aut.</sZ>
<sZ>2 aut.</sZ>
<sZ>4 aut.</sZ>
<sZ>5 aut.</sZ>
<sZ>6 aut.</sZ>
</inist:fA14>
<country>Royaume-Uni</country>
<placeName><settlement type="city">Londres</settlement>
<region type="country">Angleterre</region>
<region type="région" nuts="1">Grand Londres</region>
</placeName>
</affiliation>
</author>
<author><name sortKey="Gibb, Iain" sort="Gibb, Iain" uniqKey="Gibb I" first="Iain" last="Gibb">Iain Gibb</name>
<affiliation wicri:level="1"><inist:fA14 i1="02"><s1>Boots Healthcare International Ltd, Product Development (Healthcare)</s1>
<s2>Nottingham</s2>
<s3>GBR</s3>
<sZ>3 aut.</sZ>
</inist:fA14>
<country>Royaume-Uni</country>
<wicri:noRegion>Nottingham</wicri:noRegion>
</affiliation>
</author>
<author><name sortKey="Balasingam, Shobana" sort="Balasingam, Shobana" uniqKey="Balasingam S" first="Shobana" last="Balasingam">Shobana Balasingam</name>
<affiliation wicri:level="3"><inist:fA14 i1="01"><s1>Retroscreen Virology Ltd, Institute of Cell & Molecular Sciences, Barts & the Royal London, Queen Mary's School of Medicine and Dentistry</s1>
<s2>London</s2>
<s3>GBR</s3>
<sZ>1 aut.</sZ>
<sZ>2 aut.</sZ>
<sZ>4 aut.</sZ>
<sZ>5 aut.</sZ>
<sZ>6 aut.</sZ>
</inist:fA14>
<country>Royaume-Uni</country>
<placeName><settlement type="city">Londres</settlement>
<region type="country">Angleterre</region>
<region type="région" nuts="1">Grand Londres</region>
</placeName>
</affiliation>
</author>
<author><name sortKey="Chan, Charlotte" sort="Chan, Charlotte" uniqKey="Chan C" first="Charlotte" last="Chan">Charlotte Chan</name>
<affiliation wicri:level="3"><inist:fA14 i1="01"><s1>Retroscreen Virology Ltd, Institute of Cell & Molecular Sciences, Barts & the Royal London, Queen Mary's School of Medicine and Dentistry</s1>
<s2>London</s2>
<s3>GBR</s3>
<sZ>1 aut.</sZ>
<sZ>2 aut.</sZ>
<sZ>4 aut.</sZ>
<sZ>5 aut.</sZ>
<sZ>6 aut.</sZ>
</inist:fA14>
<country>Royaume-Uni</country>
<placeName><settlement type="city">Londres</settlement>
<region type="country">Angleterre</region>
<region type="région" nuts="1">Grand Londres</region>
</placeName>
</affiliation>
</author>
<author><name sortKey="Catchpole, Andrew" sort="Catchpole, Andrew" uniqKey="Catchpole A" first="Andrew" last="Catchpole">Andrew Catchpole</name>
<affiliation wicri:level="3"><inist:fA14 i1="01"><s1>Retroscreen Virology Ltd, Institute of Cell & Molecular Sciences, Barts & the Royal London, Queen Mary's School of Medicine and Dentistry</s1>
<s2>London</s2>
<s3>GBR</s3>
<sZ>1 aut.</sZ>
<sZ>2 aut.</sZ>
<sZ>4 aut.</sZ>
<sZ>5 aut.</sZ>
<sZ>6 aut.</sZ>
</inist:fA14>
<country>Royaume-Uni</country>
<placeName><settlement type="city">Londres</settlement>
<region type="country">Angleterre</region>
<region type="région" nuts="1">Grand Londres</region>
</placeName>
</affiliation>
</author>
</analytic>
<series><title level="j" type="main">Antiviral chemistry & chemotherapy</title>
<title level="j" type="abbreviated">Antivir. chem. chemother.</title>
<idno type="ISSN">0956-3202</idno>
<imprint><date when="2005">2005</date>
</imprint>
</series>
</biblStruct>
</sourceDesc>
<seriesStmt><title level="j" type="main">Antiviral chemistry & chemotherapy</title>
<title level="j" type="abbreviated">Antivir. chem. chemother.</title>
<idno type="ISSN">0956-3202</idno>
</seriesStmt>
</fileDesc>
<profileDesc><textClass><keywords scheme="KwdEn" xml:lang="en"><term>Alcohol</term>
<term>Amylmetacresol</term>
<term>Antiviral</term>
<term>Dosage form</term>
<term>Human respiratory syncytial virus</term>
<term>Influenza A</term>
<term>Influenza A virus</term>
<term>Oropharynx</term>
<term>Respiratory tract</term>
<term>Rhinovirus</term>
<term>Severe acute respiratory syndrome</term>
</keywords>
<keywords scheme="Pascal" xml:lang="fr"><term>Oropharynx</term>
<term>Alcool</term>
<term>Antiviral</term>
<term>Virus respiratoire syncytial humain</term>
<term>Voie respiratoire</term>
<term>Virus grippal A</term>
<term>Syndrome respiratoire aigu sévère</term>
<term>Grippe A</term>
<term>Rhinovirus</term>
<term>Forme pharmaceutique</term>
<term>Amylmétacrésol</term>
<term>Dichlorobenzyl Alcool</term>
</keywords>
<keywords scheme="Wicri" type="topic" xml:lang="fr"><term>Alcool</term>
</keywords>
</textClass>
</profileDesc>
</teiHeader>
<front><div type="abstract" xml:lang="en">A potent virucidal mixture containing amyl metacresol and dichlorobenzyl alcohol at low pH inactivated enveloped respiratory viruses influenza A, respiratory synctial virus (RSV) and severe acute respiratory syndrome coronavirus (SARS-CoV) but not viruses with icosahedral symmetry, such as adenoviruses or rhinoviruses. A titre of approximately 3.5 log<sub>10</sub>
TCID<sub>50</sub>
was reduced to below the level of detection within two minutes. Electron microscopy of purified influenza A virus showed extensive clumping and morphological changes in spike configuration after contact with the virucidal mixture, but no overt destruction of the viral membrane. We conclude that, formulated as a lozenge, the mixture could have significant effects in reducing the infectivity of certain infectious viruses in the throat and presumably in cough droplets, thus reducing, theoretically, opportunities for person-to-person transmission.</div>
</front>
</TEI>
<inist><standard h6="B"><pA><fA01 i1="01" i2="1"><s0>0956-3202</s0>
</fA01>
<fA03 i2="1"><s0>Antivir. chem. chemother.</s0>
</fA03>
<fA05><s2>16</s2>
</fA05>
<fA06><s2>2</s2>
</fA06>
<fA08 i1="01" i2="1" l="ENG"><s1>A throat lozenge containing amyl meta cresol and dichlorobenzyl alcohol has a direct virucidal effect on respiratory syncytial virus, influenza A and SARS-CoV</s1>
</fA08>
<fA11 i1="01" i2="1"><s1>OXFORD (John S.)</s1>
</fA11>
<fA11 i1="02" i2="1"><s1>LAMBKIN (Robert)</s1>
</fA11>
<fA11 i1="03" i2="1"><s1>GIBB (Iain)</s1>
</fA11>
<fA11 i1="04" i2="1"><s1>BALASINGAM (Shobana)</s1>
</fA11>
<fA11 i1="05" i2="1"><s1>CHAN (Charlotte)</s1>
</fA11>
<fA11 i1="06" i2="1"><s1>CATCHPOLE (Andrew)</s1>
</fA11>
<fA14 i1="01"><s1>Retroscreen Virology Ltd, Institute of Cell & Molecular Sciences, Barts & the Royal London, Queen Mary's School of Medicine and Dentistry</s1>
<s2>London</s2>
<s3>GBR</s3>
<sZ>1 aut.</sZ>
<sZ>2 aut.</sZ>
<sZ>4 aut.</sZ>
<sZ>5 aut.</sZ>
<sZ>6 aut.</sZ>
</fA14>
<fA14 i1="02"><s1>Boots Healthcare International Ltd, Product Development (Healthcare)</s1>
<s2>Nottingham</s2>
<s3>GBR</s3>
<sZ>3 aut.</sZ>
</fA14>
<fA20><s1>129-134</s1>
</fA20>
<fA21><s1>2005</s1>
</fA21>
<fA23 i1="01"><s0>ENG</s0>
</fA23>
<fA43 i1="01"><s1>INIST</s1>
<s2>22101</s2>
<s5>354000125989760050</s5>
</fA43>
<fA44><s0>0000</s0>
<s1>© 2005 INIST-CNRS. All rights reserved.</s1>
</fA44>
<fA45><s0>24 ref.</s0>
</fA45>
<fA47 i1="01" i2="1"><s0>05-0281109</s0>
</fA47>
<fA60><s1>P</s1>
</fA60>
<fA61><s0>A</s0>
</fA61>
<fA64 i1="01" i2="1"><s0>Antiviral chemistry & chemotherapy</s0>
</fA64>
<fA66 i1="01"><s0>GBR</s0>
</fA66>
<fC01 i1="01" l="ENG"><s0>A potent virucidal mixture containing amyl metacresol and dichlorobenzyl alcohol at low pH inactivated enveloped respiratory viruses influenza A, respiratory synctial virus (RSV) and severe acute respiratory syndrome coronavirus (SARS-CoV) but not viruses with icosahedral symmetry, such as adenoviruses or rhinoviruses. A titre of approximately 3.5 log<sub>10</sub>
TCID<sub>50</sub>
was reduced to below the level of detection within two minutes. Electron microscopy of purified influenza A virus showed extensive clumping and morphological changes in spike configuration after contact with the virucidal mixture, but no overt destruction of the viral membrane. We conclude that, formulated as a lozenge, the mixture could have significant effects in reducing the infectivity of certain infectious viruses in the throat and presumably in cough droplets, thus reducing, theoretically, opportunities for person-to-person transmission.</s0>
</fC01>
<fC02 i1="01" i2="X"><s0>002B02S05</s0>
</fC02>
<fC03 i1="01" i2="X" l="FRE"><s0>Oropharynx</s0>
<s5>01</s5>
</fC03>
<fC03 i1="01" i2="X" l="ENG"><s0>Oropharynx</s0>
<s5>01</s5>
</fC03>
<fC03 i1="01" i2="X" l="SPA"><s0>Orofaringe</s0>
<s5>01</s5>
</fC03>
<fC03 i1="02" i2="X" l="FRE"><s0>Alcool</s0>
<s5>02</s5>
</fC03>
<fC03 i1="02" i2="X" l="ENG"><s0>Alcohol</s0>
<s5>02</s5>
</fC03>
<fC03 i1="02" i2="X" l="SPA"><s0>Alcohol</s0>
<s5>02</s5>
</fC03>
<fC03 i1="03" i2="X" l="FRE"><s0>Antiviral</s0>
<s5>03</s5>
</fC03>
<fC03 i1="03" i2="X" l="ENG"><s0>Antiviral</s0>
<s5>03</s5>
</fC03>
<fC03 i1="03" i2="X" l="SPA"><s0>Antiviral</s0>
<s5>03</s5>
</fC03>
<fC03 i1="04" i2="X" l="FRE"><s0>Virus respiratoire syncytial humain</s0>
<s2>NW</s2>
<s5>04</s5>
</fC03>
<fC03 i1="04" i2="X" l="ENG"><s0>Human respiratory syncytial virus</s0>
<s2>NW</s2>
<s5>04</s5>
</fC03>
<fC03 i1="04" i2="X" l="SPA"><s0>Human respiratory syncytial virus</s0>
<s2>NW</s2>
<s5>04</s5>
</fC03>
<fC03 i1="05" i2="X" l="FRE"><s0>Voie respiratoire</s0>
<s5>05</s5>
</fC03>
<fC03 i1="05" i2="X" l="ENG"><s0>Respiratory tract</s0>
<s5>05</s5>
</fC03>
<fC03 i1="05" i2="X" l="SPA"><s0>Vía respiratoria</s0>
<s5>05</s5>
</fC03>
<fC03 i1="06" i2="X" l="FRE"><s0>Virus grippal A</s0>
<s2>NW</s2>
<s5>06</s5>
</fC03>
<fC03 i1="06" i2="X" l="ENG"><s0>Influenza A virus</s0>
<s2>NW</s2>
<s5>06</s5>
</fC03>
<fC03 i1="06" i2="X" l="SPA"><s0>Influenza A virus</s0>
<s2>NW</s2>
<s5>06</s5>
</fC03>
<fC03 i1="07" i2="X" l="FRE"><s0>Syndrome respiratoire aigu sévère</s0>
<s2>NM</s2>
<s5>08</s5>
</fC03>
<fC03 i1="07" i2="X" l="ENG"><s0>Severe acute respiratory syndrome</s0>
<s2>NM</s2>
<s5>08</s5>
</fC03>
<fC03 i1="07" i2="X" l="SPA"><s0>Síndrome respiratorio agudo severo</s0>
<s2>NM</s2>
<s5>08</s5>
</fC03>
<fC03 i1="08" i2="X" l="FRE"><s0>Grippe A</s0>
<s5>09</s5>
</fC03>
<fC03 i1="08" i2="X" l="ENG"><s0>Influenza A</s0>
<s5>09</s5>
</fC03>
<fC03 i1="08" i2="X" l="SPA"><s0>Gripe A</s0>
<s5>09</s5>
</fC03>
<fC03 i1="09" i2="X" l="FRE"><s0>Rhinovirus</s0>
<s2>NW</s2>
<s5>10</s5>
</fC03>
<fC03 i1="09" i2="X" l="ENG"><s0>Rhinovirus</s0>
<s2>NW</s2>
<s5>10</s5>
</fC03>
<fC03 i1="09" i2="X" l="SPA"><s0>Rhinovirus</s0>
<s2>NW</s2>
<s5>10</s5>
</fC03>
<fC03 i1="10" i2="X" l="FRE"><s0>Forme pharmaceutique</s0>
<s5>11</s5>
</fC03>
<fC03 i1="10" i2="X" l="ENG"><s0>Dosage form</s0>
<s5>11</s5>
</fC03>
<fC03 i1="10" i2="X" l="SPA"><s0>Forma farmacéutica</s0>
<s5>11</s5>
</fC03>
<fC03 i1="11" i2="X" l="FRE"><s0>Amylmétacrésol</s0>
<s2>NK</s2>
<s2>FR</s2>
<s5>12</s5>
</fC03>
<fC03 i1="11" i2="X" l="ENG"><s0>Amylmetacresol</s0>
<s2>NK</s2>
<s2>FR</s2>
<s5>12</s5>
</fC03>
<fC03 i1="11" i2="X" l="SPA"><s0>Amilmetacresol</s0>
<s2>NK</s2>
<s2>FR</s2>
<s5>12</s5>
</fC03>
<fC03 i1="12" i2="X" l="FRE"><s0>Dichlorobenzyl Alcool</s0>
<s4>INC</s4>
<s5>86</s5>
</fC03>
<fC07 i1="01" i2="X" l="FRE"><s0>Pneumovirus</s0>
<s2>NW</s2>
</fC07>
<fC07 i1="01" i2="X" l="ENG"><s0>Pneumovirus</s0>
<s2>NW</s2>
</fC07>
<fC07 i1="01" i2="X" l="SPA"><s0>Pneumovirus</s0>
<s2>NW</s2>
</fC07>
<fC07 i1="02" i2="X" l="FRE"><s0>Pneumovirinae</s0>
<s2>NW</s2>
</fC07>
<fC07 i1="02" i2="X" l="ENG"><s0>Pneumovirinae</s0>
<s2>NW</s2>
</fC07>
<fC07 i1="02" i2="X" l="SPA"><s0>Pneumovirinae</s0>
<s2>NW</s2>
</fC07>
<fC07 i1="03" i2="X" l="FRE"><s0>Paramyxoviridae</s0>
<s2>NW</s2>
</fC07>
<fC07 i1="03" i2="X" l="ENG"><s0>Paramyxoviridae</s0>
<s2>NW</s2>
</fC07>
<fC07 i1="03" i2="X" l="SPA"><s0>Paramyxoviridae</s0>
<s2>NW</s2>
</fC07>
<fC07 i1="04" i2="X" l="FRE"><s0>Mononegavirales</s0>
<s2>NW</s2>
</fC07>
<fC07 i1="04" i2="X" l="ENG"><s0>Mononegavirales</s0>
<s2>NW</s2>
</fC07>
<fC07 i1="04" i2="X" l="SPA"><s0>Mononegavirales</s0>
<s2>NW</s2>
</fC07>
<fC07 i1="05" i2="X" l="FRE"><s0>Virus</s0>
<s2>NW</s2>
</fC07>
<fC07 i1="05" i2="X" l="ENG"><s0>Virus</s0>
<s2>NW</s2>
</fC07>
<fC07 i1="05" i2="X" l="SPA"><s0>Virus</s0>
<s2>NW</s2>
</fC07>
<fC07 i1="06" i2="X" l="FRE"><s0>Influenzavirus A</s0>
<s2>NW</s2>
</fC07>
<fC07 i1="06" i2="X" l="ENG"><s0>Influenzavirus A</s0>
<s2>NW</s2>
</fC07>
<fC07 i1="06" i2="X" l="SPA"><s0>Influenzavirus A</s0>
<s2>NW</s2>
</fC07>
<fC07 i1="07" i2="X" l="FRE"><s0>Orthomyxoviridae</s0>
<s2>NW</s2>
</fC07>
<fC07 i1="07" i2="X" l="ENG"><s0>Orthomyxoviridae</s0>
<s2>NW</s2>
</fC07>
<fC07 i1="07" i2="X" l="SPA"><s0>Orthomyxoviridae</s0>
<s2>NW</s2>
</fC07>
<fC07 i1="08" i2="X" l="FRE"><s0>Virose</s0>
</fC07>
<fC07 i1="08" i2="X" l="ENG"><s0>Viral disease</s0>
</fC07>
<fC07 i1="08" i2="X" l="SPA"><s0>Virosis</s0>
</fC07>
<fC07 i1="09" i2="X" l="FRE"><s0>Infection</s0>
</fC07>
<fC07 i1="09" i2="X" l="ENG"><s0>Infection</s0>
</fC07>
<fC07 i1="09" i2="X" l="SPA"><s0>Infección</s0>
</fC07>
<fC07 i1="10" i2="X" l="FRE"><s0>Picornaviridae</s0>
<s2>NW</s2>
</fC07>
<fC07 i1="10" i2="X" l="ENG"><s0>Picornaviridae</s0>
<s2>NW</s2>
</fC07>
<fC07 i1="10" i2="X" l="SPA"><s0>Picornaviridae</s0>
<s2>NW</s2>
</fC07>
<fC07 i1="11" i2="X" l="FRE"><s0>Appareil respiratoire pathologie</s0>
<s5>37</s5>
</fC07>
<fC07 i1="11" i2="X" l="ENG"><s0>Respiratory disease</s0>
<s5>37</s5>
</fC07>
<fC07 i1="11" i2="X" l="SPA"><s0>Aparato respiratorio patología</s0>
<s5>37</s5>
</fC07>
<fC07 i1="12" i2="X" l="FRE"><s0>Poumon pathologie</s0>
<s5>38</s5>
</fC07>
<fC07 i1="12" i2="X" l="ENG"><s0>Lung disease</s0>
<s5>38</s5>
</fC07>
<fC07 i1="12" i2="X" l="SPA"><s0>Pulmón patología</s0>
<s5>38</s5>
</fC07>
<fN21><s1>192</s1>
</fN21>
</pA>
</standard>
</inist>
<affiliations><list><country><li>Royaume-Uni</li>
</country>
<region><li>Angleterre</li>
<li>Grand Londres</li>
</region>
<settlement><li>Londres</li>
</settlement>
</list>
<tree><country name="Royaume-Uni"><region name="Angleterre"><name sortKey="Oxford, John S" sort="Oxford, John S" uniqKey="Oxford J" first="John S." last="Oxford">John S. Oxford</name>
</region>
<name sortKey="Balasingam, Shobana" sort="Balasingam, Shobana" uniqKey="Balasingam S" first="Shobana" last="Balasingam">Shobana Balasingam</name>
<name sortKey="Catchpole, Andrew" sort="Catchpole, Andrew" uniqKey="Catchpole A" first="Andrew" last="Catchpole">Andrew Catchpole</name>
<name sortKey="Chan, Charlotte" sort="Chan, Charlotte" uniqKey="Chan C" first="Charlotte" last="Chan">Charlotte Chan</name>
<name sortKey="Gibb, Iain" sort="Gibb, Iain" uniqKey="Gibb I" first="Iain" last="Gibb">Iain Gibb</name>
<name sortKey="Lambkin, Robert" sort="Lambkin, Robert" uniqKey="Lambkin R" first="Robert" last="Lambkin">Robert Lambkin</name>
</country>
</tree>
</affiliations>
</record>
Pour manipuler ce document sous Unix (Dilib)
EXPLOR_STEP=$WICRI_ROOT/Sante/explor/SrasV1/Data/PascalFrancis/Checkpoint
HfdSelect -h $EXPLOR_STEP/biblio.hfd -nk 000716 | SxmlIndent | more
Ou
HfdSelect -h $EXPLOR_AREA/Data/PascalFrancis/Checkpoint/biblio.hfd -nk 000716 | SxmlIndent | more
Pour mettre un lien sur cette page dans le réseau Wicri
{{Explor lien |wiki= Sante |area= SrasV1 |flux= PascalFrancis |étape= Checkpoint |type= RBID |clé= Pascal:05-0281109 |texte= A throat lozenge containing amyl meta cresol and dichlorobenzyl alcohol has a direct virucidal effect on respiratory syncytial virus, influenza A and SARS-CoV }}
![]() | This area was generated with Dilib version V0.6.33. | ![]() |