[Study on T cell subsets and their activated molecules from the convalescent SARS patients during two follow-up surveys].
Identifieur interne : 000865 ( Ncbi/Merge ); précédent : 000864; suivant : 000866[Study on T cell subsets and their activated molecules from the convalescent SARS patients during two follow-up surveys].
Auteurs : Cui Cai [République populaire de Chine] ; Xing Zeng ; Ai-Hua Ou ; Yu Huang ; Xian ZhangSource :
- Xi bao yu fen zi mian yi xue za zhi = Chinese journal of cellular and molecular immunology [ 1007-8738 ] ; 2004.
Descripteurs français
- KwdFr :
- MESH :
English descriptors
- KwdEn :
- MESH :
- chemical , metabolism : CD3 Complex, CD4 Antigens, CD8 Antigens.
- immunology : Severe Acute Respiratory Syndrome, T-Lymphocyte Subsets.
- CD4-CD8 Ratio, Convalescence, Flow Cytometry, Follow-Up Studies, Humans, Lymphocyte Count.
Abstract
To explore the changes of peripheral blood T cell subsets and their activated molecules in convalescent SARS patients.
PubMed: 15193228
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pubmed:15193228Le document en format XML
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<author><name sortKey="Cai, Cui" sort="Cai, Cui" uniqKey="Cai C" first="Cui" last="Cai">Cui Cai</name>
<affiliation wicri:level="1"><nlm:affiliation>The Central Laboratory, Guangdong Provincial Hospital of TCM, Guangzhou 510120, China. X-Zeng@21cn.com</nlm:affiliation>
<country xml:lang="fr">République populaire de Chine</country>
<wicri:regionArea>The Central Laboratory, Guangdong Provincial Hospital of TCM, Guangzhou 510120</wicri:regionArea>
<placeName><settlement type="city">Jiangmen</settlement>
<region type="province">Guangdong</region>
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<author><name sortKey="Zeng, Xing" sort="Zeng, Xing" uniqKey="Zeng X" first="Xing" last="Zeng">Xing Zeng</name>
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<author><name sortKey="Ou, Ai Hua" sort="Ou, Ai Hua" uniqKey="Ou A" first="Ai-Hua" last="Ou">Ai-Hua Ou</name>
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<author><name sortKey="Huang, Yu" sort="Huang, Yu" uniqKey="Huang Y" first="Yu" last="Huang">Yu Huang</name>
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<author><name sortKey="Zhang, Xian" sort="Zhang, Xian" uniqKey="Zhang X" first="Xian" last="Zhang">Xian Zhang</name>
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<affiliation wicri:level="1"><nlm:affiliation>The Central Laboratory, Guangdong Provincial Hospital of TCM, Guangzhou 510120, China. X-Zeng@21cn.com</nlm:affiliation>
<country xml:lang="fr">République populaire de Chine</country>
<wicri:regionArea>The Central Laboratory, Guangdong Provincial Hospital of TCM, Guangzhou 510120</wicri:regionArea>
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<author><name sortKey="Zeng, Xing" sort="Zeng, Xing" uniqKey="Zeng X" first="Xing" last="Zeng">Xing Zeng</name>
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<author><name sortKey="Ou, Ai Hua" sort="Ou, Ai Hua" uniqKey="Ou A" first="Ai-Hua" last="Ou">Ai-Hua Ou</name>
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<author><name sortKey="Huang, Yu" sort="Huang, Yu" uniqKey="Huang Y" first="Yu" last="Huang">Yu Huang</name>
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<author><name sortKey="Zhang, Xian" sort="Zhang, Xian" uniqKey="Zhang X" first="Xian" last="Zhang">Xian Zhang</name>
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<series><title level="j">Xi bao yu fen zi mian yi xue za zhi = Chinese journal of cellular and molecular immunology</title>
<idno type="ISSN">1007-8738</idno>
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<profileDesc><textClass><keywords scheme="KwdEn" xml:lang="en"><term>CD3 Complex (metabolism)</term>
<term>CD4 Antigens (metabolism)</term>
<term>CD4-CD8 Ratio</term>
<term>CD8 Antigens (metabolism)</term>
<term>Convalescence</term>
<term>Flow Cytometry</term>
<term>Follow-Up Studies</term>
<term>Humans</term>
<term>Lymphocyte Count</term>
<term>Severe Acute Respiratory Syndrome (immunology)</term>
<term>T-Lymphocyte Subsets (immunology)</term>
</keywords>
<keywords scheme="KwdFr" xml:lang="fr"><term>Convalescence</term>
<term>Cytométrie en flux</term>
<term>Humains</term>
<term>Numération des lymphocytes</term>
<term>Rapport CD4-CD8</term>
<term>Sous-populations de lymphocytes T (immunologie)</term>
<term>Syndrome respiratoire aigu sévère (immunologie)</term>
<term>Études de suivi</term>
</keywords>
<keywords scheme="MESH" type="chemical" qualifier="metabolism" xml:lang="en"><term>CD3 Complex</term>
<term>CD4 Antigens</term>
<term>CD8 Antigens</term>
</keywords>
<keywords scheme="MESH" qualifier="immunologie" xml:lang="fr"><term>Sous-populations de lymphocytes T</term>
<term>Syndrome respiratoire aigu sévère</term>
</keywords>
<keywords scheme="MESH" qualifier="immunology" xml:lang="en"><term>Severe Acute Respiratory Syndrome</term>
<term>T-Lymphocyte Subsets</term>
</keywords>
<keywords scheme="MESH" xml:lang="en"><term>CD4-CD8 Ratio</term>
<term>Convalescence</term>
<term>Flow Cytometry</term>
<term>Follow-Up Studies</term>
<term>Humans</term>
<term>Lymphocyte Count</term>
</keywords>
<keywords scheme="MESH" xml:lang="fr"><term>Convalescence</term>
<term>Cytométrie en flux</term>
<term>Humains</term>
<term>Numération des lymphocytes</term>
<term>Rapport CD4-CD8</term>
<term>Études de suivi</term>
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<front><div type="abstract" xml:lang="en">To explore the changes of peripheral blood T cell subsets and their activated molecules in convalescent SARS patients.</div>
</front>
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<pubmed><MedlineCitation Status="MEDLINE" Owner="NLM"><PMID Version="1">15193228</PMID>
<DateCompleted><Year>2004</Year>
<Month>12</Month>
<Day>14</Day>
</DateCompleted>
<DateRevised><Year>2017</Year>
<Month>11</Month>
<Day>16</Day>
</DateRevised>
<Article PubModel="Print"><Journal><ISSN IssnType="Print">1007-8738</ISSN>
<JournalIssue CitedMedium="Print"><Volume>20</Volume>
<Issue>3</Issue>
<PubDate><Year>2004</Year>
<Month>May</Month>
</PubDate>
</JournalIssue>
<Title>Xi bao yu fen zi mian yi xue za zhi = Chinese journal of cellular and molecular immunology</Title>
<ISOAbbreviation>Xi Bao Yu Fen Zi Mian Yi Xue Za Zhi</ISOAbbreviation>
</Journal>
<ArticleTitle>[Study on T cell subsets and their activated molecules from the convalescent SARS patients during two follow-up surveys].</ArticleTitle>
<Pagination><MedlinePgn>322-4</MedlinePgn>
</Pagination>
<Abstract><AbstractText Label="AIM" NlmCategory="OBJECTIVE">To explore the changes of peripheral blood T cell subsets and their activated molecules in convalescent SARS patients.</AbstractText>
<AbstractText Label="METHODS" NlmCategory="METHODS">In two follow-up surveys of the SARS patients discharged from our hospital, the changes of CD3(+), CD4(+), CD8(+), CD8(+) CD28(+), CD8(+) CD28(-), CD3(+) CD25(+), CD3(+) CD69(+), CD3(+) HLA-DR(+)T cells and the ratio of CD4(+)/CD8(+) T cells in peripheral blood of SARS patients treated unitedly with Chinese and Western medicines were detected by flow cytometry.</AbstractText>
<AbstractText Label="RESULTS" NlmCategory="RESULTS">In two follow-up surveys, the percentages of CD3(+), CD4(+), CD8(+) CD28(+) T cells and the ratio of CD4(+)/CD8(+) T cells were remarkably lower than those of normal values(P<0.05), while the percentage of CD8(+) CD28 (-) T cells was higher(P<0.01). As for the percentages of CD3(+), CD8(+), CD4(+)/CD8(+), CD3(+) CD25(+), CD3(+) CD69(+) and CD3(+) HLA-DR(+) T cells, there was marked difference between 1st and 2nd follow-up results, but for other molecules there was no notable difference.</AbstractText>
<AbstractText Label="CONCLUSION" NlmCategory="CONCLUSIONS">The convalescent SARS patients' immune function gradually recovers, and the effect of SARS virus on activation of T cells gradually disappears.</AbstractText>
</Abstract>
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<AffiliationInfo><Affiliation>The Central Laboratory, Guangdong Provincial Hospital of TCM, Guangzhou 510120, China. X-Zeng@21cn.com</Affiliation>
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<MeshHeading><DescriptorName UI="D005434" MajorTopicYN="N">Flow Cytometry</DescriptorName>
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<MeshHeading><DescriptorName UI="D005500" MajorTopicYN="N">Follow-Up Studies</DescriptorName>
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<MeshHeading><DescriptorName UI="D006801" MajorTopicYN="N">Humans</DescriptorName>
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<MeshHeading><DescriptorName UI="D018655" MajorTopicYN="N">Lymphocyte Count</DescriptorName>
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