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Factors Associated with Psychosis among Patients with Severe Acute Respiratory Syndrome: A Case-Control Study

Identifieur interne : 005A19 ( Main/Merge ); précédent : 005A18; suivant : 005A20

Factors Associated with Psychosis among Patients with Severe Acute Respiratory Syndrome: A Case-Control Study

Auteurs : Dominic T. S. Lee [Hong Kong, États-Unis] ; Y. K. Wing [Hong Kong] ; Henry C. M. Leung [Hong Kong] ; Joseph J. Y. Sung [Hong Kong] ; Y. K. Ng [Hong Kong] ; G. C. Yiu [Hong Kong] ; Ronald Y. L. Chen [Hong Kong] ; Helen F. K. Chiu [Hong Kong]

Source :

RBID : ISTEX:E7E41992DB27E1F0355C80C6068BAD97A75B3920

Abstract

We observed that a number of patients with severe acute respiratory syndrome (SARS) developed affective psychosis during the acute phase of their illness. We reviewed all SARS-related psychiatric consultations in Hong Kong and investigated the risk factors for psychosis among patients with SARS in a matched case-control study. Patients with SARS-related psychosis received higher total doses of steroids and had higher rates of family history of psychiatric illness. The findings of the present study suggest that steroid toxicity, personal vulnerability, and, probably, psychosocial stressors jointly contributed to the development of psychosis in patients with SARS.

Url:
DOI: 10.1086/424016

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ISTEX:E7E41992DB27E1F0355C80C6068BAD97A75B3920

Le document en format XML

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<title xml:lang="en" level="a" type="main">Factors Associated with Psychosis among Patients with Severe Acute Respiratory Syndrome: A Case-Control Study</title>
<author>
<name sortKey="Lee, Dominic T S" sort="Lee, Dominic T S" uniqKey="Lee D" first="Dominic T. S." last="Lee">Dominic T. S. Lee</name>
<affiliation>
<nlm:aff id="aff1">
<institution>Department of Psychiatry, The Chinese University of Hong Kong</institution>
,
<addr-line>Hong Kong</addr-line>
</nlm:aff>
</affiliation>
<affiliation wicri:level="2">
<nlm:aff id="aff4">
<institution>Department of Social Medicine, Harvard Medical School</institution>
,
<addr-line>Boston, Massachusetts</addr-line>
</nlm:aff>
<country xml:lang="fr">États-Unis</country>
<placeName>
<region type="state">Massachusetts</region>
</placeName>
<wicri:cityArea>Boston</wicri:cityArea>
</affiliation>
</author>
<author>
<name sortKey="Wing, Y K" sort="Wing, Y K" uniqKey="Wing Y" first="Y. K." last="Wing">Y. K. Wing</name>
<affiliation>
<nlm:aff id="aff1">
<institution>Department of Psychiatry, The Chinese University of Hong Kong</institution>
,
<addr-line>Hong Kong</addr-line>
</nlm:aff>
</affiliation>
</author>
<author>
<name sortKey="Leung, Henry C M" sort="Leung, Henry C M" uniqKey="Leung H" first="Henry C. M." last="Leung">Henry C. M. Leung</name>
<affiliation>
<nlm:aff id="aff1">
<institution>Department of Psychiatry, The Chinese University of Hong Kong</institution>
,
<addr-line>Hong Kong</addr-line>
</nlm:aff>
</affiliation>
</author>
<author>
<name sortKey="Sung, Joseph J Y" sort="Sung, Joseph J Y" uniqKey="Sung J" first="Joseph J. Y." last="Sung">Joseph J. Y. Sung</name>
<affiliation>
<nlm:aff id="aff2">
<institution>Department of Medicine and Therapeutics, The Chinese University of Hong Kong</institution>
,
<addr-line>Hong Kong</addr-line>
</nlm:aff>
</affiliation>
</author>
<author>
<name sortKey="Ng, Y K" sort="Ng, Y K" uniqKey="Ng Y" first="Y. K." last="Ng">Y. K. Ng</name>
<affiliation>
<nlm:aff id="aff1">
<institution>Department of Psychiatry, The Chinese University of Hong Kong</institution>
,
<addr-line>Hong Kong</addr-line>
</nlm:aff>
</affiliation>
</author>
<author>
<name sortKey="Yiu, G C" sort="Yiu, G C" uniqKey="Yiu G" first="G. C." last="Yiu">G. C. Yiu</name>
<affiliation>
<nlm:aff id="aff1">
<institution>Department of Psychiatry, The Chinese University of Hong Kong</institution>
,
<addr-line>Hong Kong</addr-line>
</nlm:aff>
</affiliation>
</author>
<author>
<name sortKey="Chen, Ronald Y L" sort="Chen, Ronald Y L" uniqKey="Chen R" first="Ronald Y. L." last="Chen">Ronald Y. L. Chen</name>
<affiliation>
<nlm:aff id="aff3">
<institution>Department of Psychiatry, Hong Kong University</institution>
,
<addr-line>Hong Kong</addr-line>
</nlm:aff>
</affiliation>
</author>
<author>
<name sortKey="Chiu, Helen F K" sort="Chiu, Helen F K" uniqKey="Chiu H" first="Helen F. K." last="Chiu">Helen F. K. Chiu</name>
<affiliation>
<nlm:aff id="aff1">
<institution>Department of Psychiatry, The Chinese University of Hong Kong</institution>
,
<addr-line>Hong Kong</addr-line>
</nlm:aff>
</affiliation>
</author>
</analytic>
<series>
<title level="j">Clinical Infectious Diseases: An Official Publication of the Infectious Diseases Society of America</title>
<idno type="ISSN">1058-4838</idno>
<idno type="eISSN">1537-6591</idno>
<imprint>
<date when="2004">2004</date>
</imprint>
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<div type="abstract" xml:lang="en">
<title>Abstract</title>
<p>We observed that a number of patients with severe acute respiratory syndrome (SARS) developed affective psychosis during the acute phase of their illness. We reviewed all SARS-related psychiatric consultations in Hong Kong and investigated the risk factors for psychosis among patients with SARS in a matched case-control study. Patients with SARS-related psychosis received higher total doses of steroids and had higher rates of family history of psychiatric illness. The findings of the present study suggest that steroid toxicity, personal vulnerability, and, probably, psychosocial stressors jointly contributed to the development of psychosis in patients with SARS.</p>
</div>
</front>
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<name sortKey="Cheng, Cc" uniqKey="Cheng C">CC Cheng</name>
</author>
<author>
<name sortKey="Hung, Fn" uniqKey="Hung F">FN Hung</name>
</author>
<author>
<name sortKey="Tang, Sf" uniqKey="Tang S">SF Tang</name>
</author>
</analytic>
</biblStruct>
<biblStruct>
<analytic>
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</author>
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</author>
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<analytic>
<author>
<name sortKey="First, Mb" uniqKey="First M">MB First</name>
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<name sortKey="Spitzer, Rl" uniqKey="Spitzer R">RL Spitzer</name>
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</author>
</analytic>
</biblStruct>
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