Factors Associated with Psychosis among Patients with Severe Acute Respiratory Syndrome: A Case-Control Study
Identifieur interne : 000B20 ( Ncbi/Checkpoint ); précédent : 000B19; suivant : 000B21Factors Associated with Psychosis among Patients with Severe Acute Respiratory Syndrome: A Case-Control Study
Auteurs : Dominic T. S. Lee [États-Unis] ; Y. K. Wing ; Henry C. M. Leung ; Joseph J. Y. Sung ; Y. K. Ng ; G. C. Yiu ; Ronald Y. L. Chen ; Helen F. K. ChiuSource :
- Clinical Infectious Diseases: An Official Publication of the Infectious Diseases Society of America [ 1058-4838 ] ; 2004.
Abstract
We observed that a number of patients with severe acute respiratory syndrome (SARS) developed affective psychosis during the acute phase of their illness. We reviewed all SARS-related psychiatric consultations in Hong Kong and investigated the risk factors for psychosis among patients with SARS in a matched case-control study. Patients with SARS-related psychosis received higher total doses of steroids and had higher rates of family history of psychiatric illness. The findings of the present study suggest that steroid toxicity, personal vulnerability, and, probably, psychosocial stressors jointly contributed to the development of psychosis in patients with SARS.
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DOI: 10.1086/424016
PubMed: 15486852
PubMed Central: 7107870
Affiliations:
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<front><div type="abstract" xml:lang="en"><title>Abstract</title>
<p>We observed that a number of patients with severe acute respiratory syndrome (SARS) developed affective psychosis during the acute phase of their illness. We reviewed all SARS-related psychiatric consultations in Hong Kong and investigated the risk factors for psychosis among patients with SARS in a matched case-control study. Patients with SARS-related psychosis received higher total doses of steroids and had higher rates of family history of psychiatric illness. The findings of the present study suggest that steroid toxicity, personal vulnerability, and, probably, psychosocial stressors jointly contributed to the development of psychosis in patients with SARS.</p>
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