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[Receptor-binding ability of fragments 260-600 and 397-796 of SARS-associated coronavirus spike protein].

Identifieur interne : 004749 ( Main/Merge ); précédent : 004748; suivant : 004750

[Receptor-binding ability of fragments 260-600 and 397-796 of SARS-associated coronavirus spike protein].

Auteurs : Hai-Yan Wei [République populaire de Chine] ; Jian-Wei Wang ; Yang-Jing Ou ; Yan-Bin Wang ; Jian-Guo Qu ; Wei-Ming Zhao ; Tao Hong

Source :

RBID : pubmed:16415994

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English descriptors

Abstract

To investigate the interaction between the host cell and the truncated S fragments to identify the receptor-binding domain of the spike (S) protein of SARS-associated coronavirus (SARS-CoV).

PubMed: 16415994

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pubmed:16415994

Le document en format XML

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<title xml:lang="en">[Receptor-binding ability of fragments 260-600 and 397-796 of SARS-associated coronavirus spike protein].</title>
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<name sortKey="Wei, Hai Yan" sort="Wei, Hai Yan" uniqKey="Wei H" first="Hai-Yan" last="Wei">Hai-Yan Wei</name>
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<nlm:affiliation>Institute for Viral Disease Control and Prevention, Chinese Center for Disease Control and Prevention, Beijing 100052, China.</nlm:affiliation>
<country xml:lang="fr">République populaire de Chine</country>
<wicri:regionArea>Institute for Viral Disease Control and Prevention, Chinese Center for Disease Control and Prevention, Beijing 100052</wicri:regionArea>
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<settlement type="city">Pékin</settlement>
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<name sortKey="Wang, Jian Wei" sort="Wang, Jian Wei" uniqKey="Wang J" first="Jian-Wei" last="Wang">Jian-Wei Wang</name>
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<name sortKey="Ou, Yang Jing" sort="Ou, Yang Jing" uniqKey="Ou Y" first="Yang-Jing" last="Ou">Yang-Jing Ou</name>
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<name sortKey="Wang, Yan Bin" sort="Wang, Yan Bin" uniqKey="Wang Y" first="Yan-Bin" last="Wang">Yan-Bin Wang</name>
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<name sortKey="Qu, Jian Guo" sort="Qu, Jian Guo" uniqKey="Qu J" first="Jian-Guo" last="Qu">Jian-Guo Qu</name>
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<name sortKey="Zhao, Wei Ming" sort="Zhao, Wei Ming" uniqKey="Zhao W" first="Wei-Ming" last="Zhao">Wei-Ming Zhao</name>
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<name sortKey="Hong, Tao" sort="Hong, Tao" uniqKey="Hong T" first="Tao" last="Hong">Tao Hong</name>
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<nlm:affiliation>Institute for Viral Disease Control and Prevention, Chinese Center for Disease Control and Prevention, Beijing 100052, China.</nlm:affiliation>
<country xml:lang="fr">République populaire de Chine</country>
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<name sortKey="Wang, Jian Wei" sort="Wang, Jian Wei" uniqKey="Wang J" first="Jian-Wei" last="Wang">Jian-Wei Wang</name>
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<name sortKey="Ou, Yang Jing" sort="Ou, Yang Jing" uniqKey="Ou Y" first="Yang-Jing" last="Ou">Yang-Jing Ou</name>
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<name sortKey="Wang, Yan Bin" sort="Wang, Yan Bin" uniqKey="Wang Y" first="Yan-Bin" last="Wang">Yan-Bin Wang</name>
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<name sortKey="Qu, Jian Guo" sort="Qu, Jian Guo" uniqKey="Qu J" first="Jian-Guo" last="Qu">Jian-Guo Qu</name>
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<name sortKey="Zhao, Wei Ming" sort="Zhao, Wei Ming" uniqKey="Zhao W" first="Wei-Ming" last="Zhao">Wei-Ming Zhao</name>
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<name sortKey="Hong, Tao" sort="Hong, Tao" uniqKey="Hong T" first="Tao" last="Hong">Tao Hong</name>
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<title level="j">Zhonghua shi yan he lin chuang bing du xue za zhi = Zhonghua shiyan he linchuang bingduxue zazhi = Chinese journal of experimental and clinical virology</title>
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<term>Animals</term>
<term>Binding, Competitive</term>
<term>Blotting, Western</term>
<term>Chlorocebus aethiops</term>
<term>Escherichia coli (genetics)</term>
<term>Escherichia coli (metabolism)</term>
<term>Membrane Glycoproteins (chemistry)</term>
<term>Membrane Glycoproteins (genetics)</term>
<term>Membrane Glycoproteins (metabolism)</term>
<term>Mice</term>
<term>NIH 3T3 Cells</term>
<term>Peptide Fragments (chemistry)</term>
<term>Peptide Fragments (genetics)</term>
<term>Peptide Fragments (metabolism)</term>
<term>Protein Binding</term>
<term>Receptors, Cell Surface (metabolism)</term>
<term>Recombinant Proteins (isolation & purification)</term>
<term>Recombinant Proteins (metabolism)</term>
<term>SARS Virus (genetics)</term>
<term>SARS Virus (metabolism)</term>
<term>Spike Glycoprotein, Coronavirus</term>
<term>Vero Cells</term>
<term>Viral Envelope Proteins (chemistry)</term>
<term>Viral Envelope Proteins (genetics)</term>
<term>Viral Envelope Proteins (metabolism)</term>
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<term>Animaux</term>
<term>Cellules NIH 3T3</term>
<term>Cellules Vero</term>
<term>Escherichia coli (génétique)</term>
<term>Escherichia coli (métabolisme)</term>
<term>Fixation compétitive</term>
<term>Fragments peptidiques ()</term>
<term>Fragments peptidiques (génétique)</term>
<term>Fragments peptidiques (métabolisme)</term>
<term>Glycoprotéine de spicule des coronavirus</term>
<term>Glycoprotéines membranaires ()</term>
<term>Glycoprotéines membranaires (génétique)</term>
<term>Glycoprotéines membranaires (métabolisme)</term>
<term>Liaison aux protéines</term>
<term>Protéines de l'enveloppe virale ()</term>
<term>Protéines de l'enveloppe virale (génétique)</term>
<term>Protéines de l'enveloppe virale (métabolisme)</term>
<term>Protéines recombinantes (isolement et purification)</term>
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<term>Technique de Western</term>
<term>Virus du SRAS (génétique)</term>
<term>Virus du SRAS (métabolisme)</term>
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<term>Membrane Glycoproteins</term>
<term>Peptide Fragments</term>
<term>Viral Envelope Proteins</term>
</keywords>
<keywords scheme="MESH" qualifier="genetics" xml:lang="en">
<term>Escherichia coli</term>
<term>Membrane Glycoproteins</term>
<term>Peptide Fragments</term>
<term>SARS Virus</term>
<term>Viral Envelope Proteins</term>
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<keywords scheme="MESH" qualifier="génétique" xml:lang="fr">
<term>Escherichia coli</term>
<term>Fragments peptidiques</term>
<term>Glycoprotéines membranaires</term>
<term>Protéines de l'enveloppe virale</term>
<term>Virus du SRAS</term>
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<term>Protéines recombinantes</term>
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<keywords scheme="MESH" qualifier="metabolism" xml:lang="en">
<term>Escherichia coli</term>
<term>Membrane Glycoproteins</term>
<term>Peptide Fragments</term>
<term>Receptors, Cell Surface</term>
<term>Recombinant Proteins</term>
<term>SARS Virus</term>
<term>Viral Envelope Proteins</term>
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<term>Escherichia coli</term>
<term>Fragments peptidiques</term>
<term>Glycoprotéines membranaires</term>
<term>Protéines de l'enveloppe virale</term>
<term>Protéines recombinantes</term>
<term>Récepteurs de surface cellulaire</term>
<term>Virus du SRAS</term>
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<keywords scheme="MESH" xml:lang="en">
<term>Animals</term>
<term>Binding, Competitive</term>
<term>Blotting, Western</term>
<term>Chlorocebus aethiops</term>
<term>Mice</term>
<term>NIH 3T3 Cells</term>
<term>Protein Binding</term>
<term>Spike Glycoprotein, Coronavirus</term>
<term>Vero Cells</term>
</keywords>
<keywords scheme="MESH" xml:lang="fr">
<term>Animaux</term>
<term>Cellules NIH 3T3</term>
<term>Cellules Vero</term>
<term>Fixation compétitive</term>
<term>Fragments peptidiques</term>
<term>Glycoprotéine de spicule des coronavirus</term>
<term>Glycoprotéines membranaires</term>
<term>Liaison aux protéines</term>
<term>Protéines de l'enveloppe virale</term>
<term>Souris</term>
<term>Technique de Western</term>
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<front>
<div type="abstract" xml:lang="en">To investigate the interaction between the host cell and the truncated S fragments to identify the receptor-binding domain of the spike (S) protein of SARS-associated coronavirus (SARS-CoV).</div>
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