Signal amplification on a DNA-tile-based biosensor with enhanced sensitivity.
Identifieur interne : 003086 ( Main/Merge ); précédent : 003085; suivant : 003087Signal amplification on a DNA-tile-based biosensor with enhanced sensitivity.
Auteurs : Chenxiang Lin [États-Unis] ; Jeanette K. Nangreave ; Zhe Li ; Yan Liu ; Hao YanSource :
- Nanomedicine (London, England) [ 1748-6963 ] ; 2008.
Descripteurs français
- KwdFr :
- MESH :
- analyse : ADN, ADN viral, Adénosine triphosphate.
- génétique : ADN, ADN viral, Virus du SRAS.
- Nanotechnologie, Reproductibilité des résultats, Techniques de biocapteur.
English descriptors
- KwdEn :
- MESH :
- chemical , analysis : Adenosine Triphosphate, DNA, DNA, Viral.
- chemical , genetics : DNA, DNA, Viral.
- genetics : SARS Virus.
- methods : Biosensing Techniques, Nanotechnology.
- Reproducibility of Results.
Abstract
Herein, we report our work to improve the detection sensitivity of a DNA-tile-based and self-assembled biosensing platform. This was achieved using hybridization chain reaction (HCR) as a signal amplifier on a water-soluble self-assembled DNA nanoarray carrying detection probes.
DOI: 10.2217/17435889.3.4.521
PubMed: 18694314
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pubmed:18694314Le document en format XML
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Nangreave</name></author><author><name sortKey="Li, Zhe" sort="Li, Zhe" uniqKey="Li Z" first="Zhe" last="Li">Zhe Li</name></author><author><name sortKey="Liu, Yan" sort="Liu, Yan" uniqKey="Liu Y" first="Yan" last="Liu">Yan Liu</name></author><author><name sortKey="Yan, Hao" sort="Yan, Hao" uniqKey="Yan H" first="Hao" last="Yan">Hao Yan</name></author></titleStmt><publicationStmt><idno type="wicri:source">PubMed</idno><date when="2008">2008</date><idno type="RBID">pubmed:18694314</idno><idno type="pmid">18694314</idno><idno type="doi">10.2217/17435889.3.4.521</idno><idno type="wicri:Area/PubMed/Corpus">001A88</idno><idno type="wicri:explorRef" wicri:stream="PubMed" wicri:step="Corpus" wicri:corpus="PubMed">001A88</idno><idno type="wicri:Area/PubMed/Curation">001A88</idno><idno type="wicri:explorRef" wicri:stream="PubMed" wicri:step="Curation">001A88</idno><idno type="wicri:Area/PubMed/Checkpoint">001A17</idno><idno type="wicri:explorRef" wicri:stream="Checkpoint" wicri:step="PubMed">001A17</idno><idno type="wicri:Area/Ncbi/Merge">001D14</idno><idno type="wicri:Area/Ncbi/Curation">001D14</idno><idno type="wicri:Area/Ncbi/Checkpoint">001D14</idno><idno type="wicri:Area/Main/Merge">003086</idno></publicationStmt><sourceDesc><biblStruct><analytic><title xml:lang="en">Signal amplification on a DNA-tile-based biosensor with enhanced sensitivity.</title><author><name sortKey="Lin, Chenxiang" sort="Lin, Chenxiang" uniqKey="Lin C" first="Chenxiang" last="Lin">Chenxiang Lin</name><affiliation wicri:level="2"><nlm:affiliation>Department of Chemistry and Biochemistry, Biodesign Institute, Arizona State University, Tempe, AZ 85287, USA.</nlm:affiliation><country xml:lang="fr">États-Unis</country><wicri:regionArea>Department of Chemistry and Biochemistry, Biodesign Institute, Arizona State University, Tempe, AZ 85287</wicri:regionArea><placeName><region type="state">Arizona</region></placeName></affiliation></author><author><name sortKey="Nangreave, Jeanette K" sort="Nangreave, Jeanette K" uniqKey="Nangreave J" first="Jeanette K" last="Nangreave">Jeanette K. Nangreave</name></author><author><name sortKey="Li, Zhe" sort="Li, Zhe" uniqKey="Li Z" first="Zhe" last="Li">Zhe Li</name></author><author><name sortKey="Liu, Yan" sort="Liu, Yan" uniqKey="Liu Y" first="Yan" last="Liu">Yan Liu</name></author><author><name sortKey="Yan, Hao" sort="Yan, Hao" uniqKey="Yan H" first="Hao" last="Yan">Hao Yan</name></author></analytic><series><title level="j">Nanomedicine (London, England)</title><idno type="eISSN">1748-6963</idno><imprint><date when="2008" type="published">2008</date></imprint></series></biblStruct></sourceDesc></fileDesc><profileDesc><textClass><keywords scheme="KwdEn" xml:lang="en"><term>Adenosine Triphosphate (analysis)</term><term>Biosensing Techniques (methods)</term><term>DNA (analysis)</term><term>DNA (genetics)</term><term>DNA, Viral (analysis)</term><term>DNA, Viral (genetics)</term><term>Nanotechnology (methods)</term><term>Reproducibility of Results</term><term>SARS Virus (genetics)</term></keywords><keywords scheme="KwdFr" xml:lang="fr"><term>ADN (analyse)</term><term>ADN (génétique)</term><term>ADN viral (analyse)</term><term>ADN viral (génétique)</term><term>Adénosine triphosphate (analyse)</term><term>Nanotechnologie ()</term><term>Reproductibilité des résultats</term><term>Techniques de biocapteur ()</term><term>Virus du SRAS (génétique)</term></keywords><keywords scheme="MESH" type="chemical" qualifier="analysis" xml:lang="en"><term>Adenosine Triphosphate</term><term>DNA</term><term>DNA, Viral</term></keywords><keywords scheme="MESH" type="chemical" qualifier="genetics" xml:lang="en"><term>DNA</term><term>DNA, Viral</term></keywords><keywords scheme="MESH" qualifier="analyse" xml:lang="fr"><term>ADN</term><term>ADN viral</term><term>Adénosine triphosphate</term></keywords><keywords scheme="MESH" qualifier="genetics" xml:lang="en"><term>SARS Virus</term></keywords><keywords scheme="MESH" qualifier="génétique" xml:lang="fr"><term>ADN</term><term>ADN viral</term><term>Virus du SRAS</term></keywords><keywords scheme="MESH" qualifier="methods" xml:lang="en"><term>Biosensing Techniques</term><term>Nanotechnology</term></keywords><keywords scheme="MESH" xml:lang="en"><term>Reproducibility of Results</term></keywords><keywords scheme="MESH" xml:lang="fr"><term>Nanotechnologie</term><term>Reproductibilité des résultats</term><term>Techniques de biocapteur</term></keywords></textClass></profileDesc></teiHeader><front><div type="abstract" xml:lang="en">Herein, we report our work to improve the detection sensitivity of a DNA-tile-based and self-assembled biosensing platform. 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