Thiazole Compounds as Antiviral Agents: An Update.
Identifieur interne : 000109 ( Main/Exploration ); précédent : 000108; suivant : 000110Thiazole Compounds as Antiviral Agents: An Update.
Auteurs : Inder P. Singh [Inde] ; Shiv Gupta [Inde] ; Sanjay Kumar [Inde]Source :
- Medicinal chemistry (Shariqah (United Arab Emirates)) [ 1875-6638 ] ; 2020.
Descripteurs français
- KwdFr :
- MESH :
English descriptors
- KwdEn :
- MESH :
- chemical , chemistry : Antiviral Agents, Thiazoles.
- chemical , pharmacology : Antiviral Agents, Thiazoles.
- drug effects : Viruses.
- Dose-Response Relationship, Drug, Microbial Sensitivity Tests, Molecular Structure, Structure-Activity Relationship.
Abstract
Thiazole is a good nucleus owing to its various pharmaceutical applications. Thiazole containing compounds (thiazoles) have shown various biological activities like antioxidant, analgesic, antibacterial, anticancer, antiallergic, antihypertensive, antiinflammatory, antimalarial, antifungal and antipsychotic. The scaffold is present in more than 18 FDA approved drugs and also in more than 70 experimental drugs. Only a few reviews are available in the literature despite its great medicinal importance. During the course of time, this scaffold has been studied extensively for its antiviral activities and provided compounds with activity in the nM range. However, no focused review is available on the compilation of antiviral activities shown by this scaffold.
DOI: 10.2174/1573406415666190614101253
PubMed: 31203807
Affiliations:
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Le document en format XML
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<front><div type="abstract" xml:lang="en">Thiazole is a good nucleus owing to its various pharmaceutical applications. Thiazole containing compounds (thiazoles) have shown various biological activities like antioxidant, analgesic, antibacterial, anticancer, antiallergic, antihypertensive, antiinflammatory, antimalarial, antifungal and antipsychotic. The scaffold is present in more than 18 FDA approved drugs and also in more than 70 experimental drugs. Only a few reviews are available in the literature despite its great medicinal importance. During the course of time, this scaffold has been studied extensively for its antiviral activities and provided compounds with activity in the nM range. However, no focused review is available on the compilation of antiviral activities shown by this scaffold.</div>
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