SrasV1, Main, Exploration, bibRecord, 004C83

Amotosalen photochemical inactivation of severe acute respiratory syndrome coronavirus in human platelet concentrates

Identifieur interne : 004C83 ( Main/Exploration ); précédent : 004C82; suivant : 004C84

Amotosalen photochemical inactivation of severe acute respiratory syndrome coronavirus in human platelet concentrates

Auteurs : D. Pinna ; A. Sampson-Johannes [États-Unis] ; M. Clementi [Italie] ; G. Poli [Italie] ; S. Rossini ; L. Lin [États-Unis] ; E. Vicenzi [Italie]

Source :

Transfusion Medicine [ 0958-7578 ] ; 2005-08.

RBID : ISTEX:0FCDF6C1FA00ECBBB72C2524AB46E4F864EBA09D

Descripteurs français

KwdFr :
- Conservation de sang (), Furocoumarines (pharmacologie), Humains, Inactivation virale (), Inactivation virale (effets des radiations), Photolyse (), Photosensibilisants (pharmacologie), Plaquettes (virologie), Stérilisation (), Thrombocytaphérèse (), Transfusion de plaquettes (), Virus du SRAS (), Virus du SRAS (effets des radiations).
MESH :
- effets des radiations : Inactivation virale, Virus du SRAS.
- pharmacologie : Furocoumarines, Photosensibilisants.
- virologie : Plaquettes.
- Conservation de sang, Humains, Inactivation virale, Photolyse, Stérilisation, Thrombocytaphérèse, Transfusion de plaquettes, Virus du SRAS.

English descriptors

KwdEn :
- Blood Platelets (virology), Blood Preservation (methods), Furocoumarins (pharmacology), Humans, Photolysis (drug effects), Photosensitizing Agents (pharmacology), Platelet Transfusion (methods), Plateletpheresis (methods), SARS Virus (drug effects), SARS Virus (radiation effects), Sterilization (methods), Virus Inactivation (drug effects), Virus Inactivation (radiation effects).
MESH :
- chemical , pharmacology : Furocoumarins, Photosensitizing Agents.
- drug effects : Photolysis, SARS Virus, Virus Inactivation.
- methods : Blood Preservation, Platelet Transfusion, Plateletpheresis, Sterilization.
- radiation effects : SARS Virus, Virus Inactivation.
- virology : Blood Platelets.
Teeft :
- Amotosalen, Amotosalen container, Apheresis platelet, Assay, Baxter healthcare, Blackwell publishing, Blood components, Blood donors, Blood safety, Blood supply, Broad spectrum, Chan, Clinical microbiology, Coronavirus, England journal, Genome, Guan, Hsr1, Hsr1 strain, Humans, Illumination container, Illumination device, Inactivation, Infectious diseases, Infectivity, Intercept blood system, Lancet, Novel coronavirus, Pathogen, Pathogen inactivation, Photochemical treatment, Plaque, Plaque assay, Platelet, Platelet transfusions, Respiratory syndrome, Respiratory syndrome coronavirus, Sars, Sars coronavirus, Sars virus inactivation, Syndrome, Transfusion, Transfusion medicine, Urbani, Urbani strain, Vicenzi, Viral, Viral infectivity, Viral stock, Window period, Wong.

Abstract

summary. A novel human coronavirus causing severe acute respiratory syndrome (SARS) emerged in epidemic form in early 2003 in China and spread worldwide in a few months. Every newly emerging human pathogen is of concern for the safety of the blood supply during and after an epidemic crisis. For this purpose, we have evaluated the inactivation of SARS‐coronavirus (CoV) in platelet concentrates using an approved pathogen inactivation device, the INTERCEPT Blood System. Apheresis platelet concentrates (APCs) were inoculated with approximately 106 pfu mL−1 of either Urbani or HSR1 isolates of SARS‐CoV. The inoculated units were mixed with 150 µm amotosalen and illuminated with 3 J cm−2 UV‐A light. The viral titres were determined by plaque formation in Vero E6 cells. Mixing SARS‐CoV with APC in the absence of any treatment decreased viral infectivity by approximately 0·5–1 log10. Following photochemical treatment, SARS‐CoV was consistently inactivated to the limit of detection in seven independent APC units. No infectious virus was detected after treatment when up to one‐third of the APC unit was assayed, demonstrating a mean log10‐reduction of >6·2. Potent inactivation of SARS‐CoV therefore extends the capability of the INTERCEPT Blood System in inactivating a broad spectrum of human pathogens including recently emerging respiratory viruses.

Url:

DOI: 10.1111/j.0958-7578.2005.00588.x

Affiliations:

Le document en format XML

<record><TEI wicri:istexFullTextTei="biblStruct"><teiHeader><fileDesc><titleStmt><title xml:lang="en">Amotosalen photochemical inactivation of severe acute respiratory syndrome coronavirus in human platelet concentrates</title>
<author><name sortKey="Pinna, D" sort="Pinna, D" uniqKey="Pinna D" first="D." last="Pinna">D. Pinna</name>
</author>
<author><name sortKey="Sampson Ohannes, A" sort="Sampson Ohannes, A" uniqKey="Sampson Ohannes A" first="A." last="Sampson-Johannes">A. Sampson-Johannes</name>
</author>
<author><name sortKey="Clementi, M" sort="Clementi, M" uniqKey="Clementi M" first="M." last="Clementi">M. Clementi</name>
</author>
<author><name sortKey="Poli, G" sort="Poli, G" uniqKey="Poli G" first="G." last="Poli">G. Poli</name>
</author>
<author><name sortKey="Rossini, S" sort="Rossini, S" uniqKey="Rossini S" first="S." last="Rossini">S. Rossini</name>
</author>
<author><name sortKey="Lin, L" sort="Lin, L" uniqKey="Lin L" first="L." last="Lin">L. Lin</name>
</author>
<author><name sortKey="Vicenzi, E" sort="Vicenzi, E" uniqKey="Vicenzi E" first="E." last="Vicenzi">E. Vicenzi</name>
</author>
</titleStmt>
<publicationStmt><idno type="wicri:source">ISTEX</idno>
<idno type="RBID">ISTEX:0FCDF6C1FA00ECBBB72C2524AB46E4F864EBA09D</idno>
<date when="2005" year="2005">2005</date>
<idno type="doi">10.1111/j.0958-7578.2005.00588.x</idno>
<idno type="url">https://api.istex.fr/ark:/67375/WNG-MSP512NR-K/fulltext.pdf</idno>
<idno type="wicri:Area/Istex/Corpus">000160</idno>
<idno type="wicri:explorRef" wicri:stream="Istex" wicri:step="Corpus" wicri:corpus="ISTEX">000160</idno>
<idno type="wicri:Area/Istex/Curation">000160</idno>
<idno type="wicri:Area/Istex/Checkpoint">001B44</idno>
<idno type="wicri:explorRef" wicri:stream="Istex" wicri:step="Checkpoint">001B44</idno>
<idno type="wicri:doubleKey">0958-7578:2005:Pinna D:amotosalen:photochemical:inactivation</idno>
<idno type="wicri:source">PubMed</idno>
<idno type="RBID">pubmed:16101804</idno>
<idno type="wicri:Area/PubMed/Corpus">002588</idno>
<idno type="wicri:explorRef" wicri:stream="PubMed" wicri:step="Corpus" wicri:corpus="PubMed">002588</idno>
<idno type="wicri:Area/PubMed/Curation">002588</idno>
<idno type="wicri:explorRef" wicri:stream="PubMed" wicri:step="Curation">002588</idno>
<idno type="wicri:Area/PubMed/Checkpoint">002839</idno>
<idno type="wicri:explorRef" wicri:stream="Checkpoint" wicri:step="PubMed">002839</idno>
<idno type="wicri:Area/Ncbi/Merge">001112</idno>
<idno type="wicri:Area/Ncbi/Curation">001112</idno>
<idno type="wicri:Area/Ncbi/Checkpoint">001112</idno>
<idno type="wicri:doubleKey">0958-7578:2005:Pinna D:amotosalen:photochemical:inactivation</idno>
<idno type="wicri:source">PMC</idno>
<idno type="url">http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7169868</idno>
<idno type="RBID">PMC:7169868</idno>
<idno type="wicri:Area/Pmc/Corpus">001506</idno>
<idno type="wicri:explorRef" wicri:stream="Pmc" wicri:step="Corpus" wicri:corpus="PMC">001506</idno>
<idno type="wicri:Area/Pmc/Curation">001506</idno>
<idno type="wicri:explorRef" wicri:stream="Pmc" wicri:step="Curation">001506</idno>
<idno type="wicri:Area/Pmc/Checkpoint">001396</idno>
<idno type="wicri:explorRef" wicri:stream="Pmc" wicri:step="Checkpoint">001396</idno>
<idno type="wicri:Area/Ncbi/Merge">003C94</idno>
<idno type="wicri:Area/Ncbi/Curation">003C94</idno>
<idno type="wicri:Area/Ncbi/Checkpoint">003C94</idno>
<idno type="wicri:doubleKey">0958-7578:2005:Pinna D:amotosalen:photochemical:inactivation</idno>
<idno type="wicri:Area/Main/Merge">005011</idno>
<idno type="wicri:Area/Main/Curation">004C83</idno>
<idno type="wicri:Area/Main/Exploration">004C83</idno>
</publicationStmt>
<sourceDesc><biblStruct><analytic><title level="a" type="main">Amotosalen photochemical inactivation of severe acute respiratory syndrome coronavirus in human platelet concentrates</title>
<author><name sortKey="Pinna, D" sort="Pinna, D" uniqKey="Pinna D" first="D." last="Pinna">D. Pinna</name>
<affiliation><wicri:noCountry code="subField"></wicri:noCountry>
</affiliation>
</author>
<author><name sortKey="Sampson Ohannes, A" sort="Sampson Ohannes, A" uniqKey="Sampson Ohannes A" first="A." last="Sampson-Johannes">A. Sampson-Johannes</name>
<affiliation wicri:level="2"><country xml:lang="fr">États-Unis</country>
<wicri:regionArea>Cerus Corporation, Concord, CA</wicri:regionArea>
<placeName><region type="state">Californie</region>
</placeName>
</affiliation>
</author>
<author><name sortKey="Clementi, M" sort="Clementi, M" uniqKey="Clementi M" first="M." last="Clementi">M. Clementi</name>
<affiliation></affiliation>
<affiliation wicri:level="1"><country xml:lang="fr">Italie</country>
<wicri:regionArea>‘Vita Salute’ San Raffaele University, School of Medicine, Milano</wicri:regionArea>
<wicri:noRegion>Milano</wicri:noRegion>
</affiliation>
</author>
<author><name sortKey="Poli, G" sort="Poli, G" uniqKey="Poli G" first="G." last="Poli">G. Poli</name>
<affiliation></affiliation>
<affiliation wicri:level="1"><country xml:lang="fr">Italie</country>
<wicri:regionArea>‘Vita Salute’ San Raffaele University, School of Medicine, Milano</wicri:regionArea>
<wicri:noRegion>Milano</wicri:noRegion>
</affiliation>
</author>
<author><name sortKey="Rossini, S" sort="Rossini, S" uniqKey="Rossini S" first="S." last="Rossini">S. Rossini</name>
<affiliation><wicri:noCountry code="subField"></wicri:noCountry>
</affiliation>
</author>
<author><name sortKey="Lin, L" sort="Lin, L" uniqKey="Lin L" first="L." last="Lin">L. Lin</name>
<affiliation wicri:level="2"><country xml:lang="fr">États-Unis</country>
<wicri:regionArea>Cerus Corporation, Concord, CA</wicri:regionArea>
<placeName><region type="state">Californie</region>
</placeName>
</affiliation>
</author>
<author><name sortKey="Vicenzi, E" sort="Vicenzi, E" uniqKey="Vicenzi E" first="E." last="Vicenzi">E. Vicenzi</name>
<affiliation></affiliation>
<affiliation wicri:level="1"><country wicri:rule="url">Italie</country>
</affiliation>
</author>
</analytic>
<monogr></monogr>
<series><title level="j" type="main">Transfusion Medicine</title>
<title level="j" type="alt">TRANSFUSION MEDICINE</title>
<idno type="ISSN">0958-7578</idno>
<idno type="eISSN">1365-3148</idno>
<imprint><biblScope unit="vol">15</biblScope>
<biblScope unit="issue">4</biblScope>
<biblScope unit="page" from="269">269</biblScope>
<biblScope unit="page" to="276">276</biblScope>
<biblScope unit="page-count">8</biblScope>
<publisher>Blackwell Science Ltd</publisher>
<pubPlace>Oxford, UK; Malden, USA</pubPlace>
<date type="published" when="2005-08">2005-08</date>
</imprint>
<idno type="ISSN">0958-7578</idno>
</series>
</biblStruct>
</sourceDesc>
<seriesStmt><idno type="ISSN">0958-7578</idno>
</seriesStmt>
</fileDesc>
<profileDesc><textClass><keywords scheme="KwdEn" xml:lang="en"><term>Blood Platelets (virology)</term>
<term>Blood Preservation (methods)</term>
<term>Furocoumarins (pharmacology)</term>
<term>Humans</term>
<term>Photolysis (drug effects)</term>
<term>Photosensitizing Agents (pharmacology)</term>
<term>Platelet Transfusion (methods)</term>
<term>Plateletpheresis (methods)</term>
<term>SARS Virus (drug effects)</term>
<term>SARS Virus (radiation effects)</term>
<term>Sterilization (methods)</term>
<term>Virus Inactivation (drug effects)</term>
<term>Virus Inactivation (radiation effects)</term>
</keywords>
<keywords scheme="KwdFr" xml:lang="fr"><term>Conservation de sang ()</term>
<term>Furocoumarines (pharmacologie)</term>
<term>Humains</term>
<term>Inactivation virale ()</term>
<term>Inactivation virale (effets des radiations)</term>
<term>Photolyse ()</term>
<term>Photosensibilisants (pharmacologie)</term>
<term>Plaquettes (virologie)</term>
<term>Stérilisation ()</term>
<term>Thrombocytaphérèse ()</term>
<term>Transfusion de plaquettes ()</term>
<term>Virus du SRAS ()</term>
<term>Virus du SRAS (effets des radiations)</term>
</keywords>
<keywords scheme="MESH" type="chemical" qualifier="pharmacology" xml:lang="en"><term>Furocoumarins</term>
<term>Photosensitizing Agents</term>
</keywords>
<keywords scheme="MESH" qualifier="drug effects" xml:lang="en"><term>Photolysis</term>
<term>SARS Virus</term>
<term>Virus Inactivation</term>
</keywords>
<keywords scheme="MESH" qualifier="effets des radiations" xml:lang="fr"><term>Inactivation virale</term>
<term>Virus du SRAS</term>
</keywords>
<keywords scheme="MESH" qualifier="methods" xml:lang="en"><term>Blood Preservation</term>
<term>Platelet Transfusion</term>
<term>Plateletpheresis</term>
<term>Sterilization</term>
</keywords>
<keywords scheme="MESH" qualifier="pharmacologie" xml:lang="fr"><term>Furocoumarines</term>
<term>Photosensibilisants</term>
</keywords>
<keywords scheme="MESH" qualifier="radiation effects" xml:lang="en"><term>SARS Virus</term>
<term>Virus Inactivation</term>
</keywords>
<keywords scheme="MESH" qualifier="virologie" xml:lang="fr"><term>Plaquettes</term>
</keywords>
<keywords scheme="MESH" qualifier="virology" xml:lang="en"><term>Blood Platelets</term>
</keywords>
<keywords scheme="Teeft" xml:lang="en"><term>Amotosalen</term>
<term>Amotosalen container</term>
<term>Apheresis platelet</term>
<term>Assay</term>
<term>Baxter healthcare</term>
<term>Blackwell publishing</term>
<term>Blood components</term>
<term>Blood donors</term>
<term>Blood safety</term>
<term>Blood supply</term>
<term>Broad spectrum</term>
<term>Chan</term>
<term>Clinical microbiology</term>
<term>Coronavirus</term>
<term>England journal</term>
<term>Genome</term>
<term>Guan</term>
<term>Hsr1</term>
<term>Hsr1 strain</term>
<term>Humans</term>
<term>Illumination container</term>
<term>Illumination device</term>
<term>Inactivation</term>
<term>Infectious diseases</term>
<term>Infectivity</term>
<term>Intercept blood system</term>
<term>Lancet</term>
<term>Novel coronavirus</term>
<term>Pathogen</term>
<term>Pathogen inactivation</term>
<term>Photochemical treatment</term>
<term>Plaque</term>
<term>Plaque assay</term>
<term>Platelet</term>
<term>Platelet transfusions</term>
<term>Respiratory syndrome</term>
<term>Respiratory syndrome coronavirus</term>
<term>Sars</term>
<term>Sars coronavirus</term>
<term>Sars virus inactivation</term>
<term>Syndrome</term>
<term>Transfusion</term>
<term>Transfusion medicine</term>
<term>Urbani</term>
<term>Urbani strain</term>
<term>Vicenzi</term>
<term>Viral</term>
<term>Viral infectivity</term>
<term>Viral stock</term>
<term>Window period</term>
<term>Wong</term>
</keywords>
<keywords scheme="MESH" xml:lang="fr"><term>Conservation de sang</term>
<term>Humains</term>
<term>Inactivation virale</term>
<term>Photolyse</term>
<term>Stérilisation</term>
<term>Thrombocytaphérèse</term>
<term>Transfusion de plaquettes</term>
<term>Virus du SRAS</term>
</keywords>
</textClass>
</profileDesc>
</teiHeader>
<front><div type="abstract" xml:lang="en">summary.  A novel human coronavirus causing severe acute respiratory syndrome (SARS) emerged in epidemic form in early 2003 in China and spread worldwide in a few months. Every newly emerging human pathogen is of concern for the safety of the blood supply during and after an epidemic crisis. For this purpose, we have evaluated the inactivation of SARS‐coronavirus (CoV) in platelet concentrates using an approved pathogen inactivation device, the INTERCEPT Blood System. Apheresis platelet concentrates (APCs) were inoculated with approximately 106 pfu mL−1 of either Urbani or HSR1 isolates of SARS‐CoV. The inoculated units were mixed with 150 µm amotosalen and illuminated with 3 J cm−2 UV‐A light. The viral titres were determined by plaque formation in Vero E6 cells. Mixing SARS‐CoV with APC in the absence of any treatment decreased viral infectivity by approximately 0·5–1 log10. Following photochemical treatment, SARS‐CoV was consistently inactivated to the limit of detection in seven independent APC units. No infectious virus was detected after treatment when up to one‐third of the APC unit was assayed, demonstrating a mean log10‐reduction of >6·2. Potent inactivation of SARS‐CoV therefore extends the capability of the INTERCEPT Blood System in inactivating a broad spectrum of human pathogens including recently emerging respiratory viruses.</div>
</front>
</TEI>
<affiliations><list><country><li>Italie</li>
<li>États-Unis</li>
</country>
<region><li>Californie</li>
</region>
</list>
<tree><noCountry><name sortKey="Pinna, D" sort="Pinna, D" uniqKey="Pinna D" first="D." last="Pinna">D. Pinna</name>
<name sortKey="Rossini, S" sort="Rossini, S" uniqKey="Rossini S" first="S." last="Rossini">S. Rossini</name>
</noCountry>
<country name="États-Unis"><region name="Californie"><name sortKey="Sampson Ohannes, A" sort="Sampson Ohannes, A" uniqKey="Sampson Ohannes A" first="A." last="Sampson-Johannes">A. Sampson-Johannes</name>
</region>
<name sortKey="Lin, L" sort="Lin, L" uniqKey="Lin L" first="L." last="Lin">L. Lin</name>
</country>
<country name="Italie"><noRegion><name sortKey="Clementi, M" sort="Clementi, M" uniqKey="Clementi M" first="M." last="Clementi">M. Clementi</name>
</noRegion>
<name sortKey="Poli, G" sort="Poli, G" uniqKey="Poli G" first="G." last="Poli">G. Poli</name>
<name sortKey="Vicenzi, E" sort="Vicenzi, E" uniqKey="Vicenzi E" first="E." last="Vicenzi">E. Vicenzi</name>
</country>
</tree>
</affiliations>
</record>

Pour manipuler ce document sous Unix (Dilib)

EXPLOR_STEP=$WICRI_ROOT/Sante/explor/SrasV1/Data/Main/Exploration

HfdSelect -h $EXPLOR_STEP/biblio.hfd -nk 004C83 | SxmlIndent | more

HfdSelect -h $EXPLOR_AREA/Data/Main/Exploration/biblio.hfd -nk 004C83 | SxmlIndent | more

Pour mettre un lien sur cette page dans le réseau Wicri

{{Explor lien
   |wiki=    Sante
   |area=    SrasV1
   |flux=    Main
   |étape=   Exploration
   |type=    RBID
   |clé=     ISTEX:0FCDF6C1FA00ECBBB72C2524AB46E4F864EBA09D
   |texte=   Amotosalen photochemical inactivation of severe acute respiratory syndrome coronavirus in human platelet concentrates
}}

This area was generated with Dilib version V0.6.33.
Data generation: Tue Apr 28 14:49:16 2020. Site generation: Sat Mar 27 22:06:49 2021

Serveur d'exploration SRAS

Amotosalen photochemical inactivation of severe acute respiratory syndrome coronavirus in human platelet concentrates

Amotosalen photochemical inactivation of severe acute respiratory syndrome coronavirus in human platelet concentrates

Source :

Descripteurs français

English descriptors

Abstract

Links toward previous steps (curation, corpus...)

Le document en format XML

Pour manipuler ce document sous Unix (Dilib)

Pour mettre un lien sur cette page dans le réseau Wicri

	Serveur d'exploration SRAS
	Attention, ce site est en cours de développement ! Attention, site généré par des moyens informatiques à partir de corpus bruts. Les informations ne sont donc pas validées.