Association of RANTES with the replication of severe acute respiratory syndrome coronavirus in THP-1 cells.
Identifieur interne : 004919 ( Main/Curation ); précédent : 004918; suivant : 004920Association of RANTES with the replication of severe acute respiratory syndrome coronavirus in THP-1 cells.
Auteurs : D. Li [Allemagne] ; N. Wu ; H. Yao ; A. Bader ; Norbert H. Brockmeyer ; P. AltmeyerSource :
- European journal of medical research [ 0949-2321 ] ; 2005.
Descripteurs français
- KwdFr :
- MESH :
- physiologie : Antiviraux, Chimiokine CCL5, Réplication virale, Virus du SRAS.
- virologie : Macrophages.
- Animaux, Cellules CHO, Cellules Vero, Cricetinae, Humains, Lignée cellulaire tumorale.
English descriptors
- KwdEn :
- MESH :
- chemical , physiology : Antiviral Agents, Chemokine CCL5.
- physiology : SARS Virus, Virus Replication.
- virology : Macrophages.
- Animals, CHO Cells, Cell Line, Tumor, Chlorocebus aethiops, Cricetinae, Humans, Vero Cells.
Abstract
Severe acute respiratory syndrome (SARS) is a novel infectious disease which is characterized by an overaggressive immune response. Chemokines are important inflammatory mediators and regulate disease due to viral infection. In previous study, we found that SARS-CoV has the ability to replicate in mononuclear cells. In present work, we sought to characterize the replication of SARS-CoV at the presence of RANTES in THP-1 cells.
PubMed: 15851378
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pubmed:15851378Le document en format XML
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<front><div type="abstract" xml:lang="en">Severe acute respiratory syndrome (SARS) is a novel infectious disease which is characterized by an overaggressive immune response. Chemokines are important inflammatory mediators and regulate disease due to viral infection. In previous study, we found that SARS-CoV has the ability to replicate in mononuclear cells. In present work, we sought to characterize the replication of SARS-CoV at the presence of RANTES in THP-1 cells.</div>
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