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Association of RANTES with the replication of severe acute respiratory syndrome coronavirus in THP-1 cells.

Identifieur interne : 004919 ( Main/Curation ); précédent : 004918; suivant : 004920

Association of RANTES with the replication of severe acute respiratory syndrome coronavirus in THP-1 cells.

Auteurs : D. Li [Allemagne] ; N. Wu ; H. Yao ; A. Bader ; Norbert H. Brockmeyer ; P. Altmeyer

Source :

RBID : pubmed:15851378

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English descriptors

Abstract

Severe acute respiratory syndrome (SARS) is a novel infectious disease which is characterized by an overaggressive immune response. Chemokines are important inflammatory mediators and regulate disease due to viral infection. In previous study, we found that SARS-CoV has the ability to replicate in mononuclear cells. In present work, we sought to characterize the replication of SARS-CoV at the presence of RANTES in THP-1 cells.

PubMed: 15851378

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pubmed:15851378

Le document en format XML

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<term>Chemokine CCL5 (physiology)</term>
<term>Chlorocebus aethiops</term>
<term>Cricetinae</term>
<term>Humans</term>
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