Mouse studies of SARS coronavirus-specific immune responses to recombinant replication-defective adenovirus expressing SARS coronavirus N protein.
Identifieur interne : 002A71 ( Main/Curation ); précédent : 002A70; suivant : 002A72Mouse studies of SARS coronavirus-specific immune responses to recombinant replication-defective adenovirus expressing SARS coronavirus N protein.
Auteurs : F W Y. Sin [République populaire de Chine] ; S C S. Cheng ; K T Chan ; L. Meng ; J. Yu ; Y. XieSource :
- Hong Kong medical journal = Xianggang yi xue za zhi [ 1024-2708 ] ; 2009.
Descripteurs français
- KwdFr :
- Adenoviridae (génétique), Animaux, Antigène HLA-A2 (génétique), Femelle, Humains, Production d'anticorps, Protéines nucléocapside (génétique), Protéines nucléocapside (immunologie), Souris, Souris de lignée BALB C, Souris transgéniques, Vaccins antiviraux (immunologie), Vecteurs génétiques, Virus du SRAS (génétique), Virus du SRAS (immunologie).
- MESH :
English descriptors
- KwdEn :
- Adenoviridae (genetics), Animals, Antibody Formation, Female, Genetic Vectors, HLA-A2 Antigen (genetics), Humans, Mice, Mice, Inbred BALB C, Mice, Transgenic, Nucleocapsid Proteins (genetics), Nucleocapsid Proteins (immunology), SARS Virus (genetics), SARS Virus (immunology), Viral Vaccines (immunology).
- MESH :
- chemical , genetics : HLA-A2 Antigen, Nucleocapsid Proteins.
- genetics : Adenoviridae, SARS Virus.
- chemical , immunology : Nucleocapsid Proteins, SARS Virus, Viral Vaccines.
- Animals, Antibody Formation, Female, Genetic Vectors, Humans, Mice, Mice, Inbred BALB C, Mice, Transgenic.
Abstract
1. A recombinant adenovirus encoding SARS coronavirus(SARS-CoV) nucleocapsid protein (rAd-N) was constructed. 2. The ability of the rAd-N to induce anti-SARS-CoV N antibody production and cellular immune responses was evaluated in an HLA-A2.1/Kb transgenic mouse model.
PubMed: 19258632
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pubmed:19258632Le document en format XML
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<term>Protéines nucléocapside (immunologie)</term>
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<front><div type="abstract" xml:lang="en">1. A recombinant adenovirus encoding SARS coronavirus(SARS-CoV) nucleocapsid protein (rAd-N) was constructed. 2. The ability of the rAd-N to induce anti-SARS-CoV N antibody production and cellular immune responses was evaluated in an HLA-A2.1/Kb transgenic mouse model.</div>
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