Mouse studies of SARS coronavirus-specific immune responses to recombinant replication-defective adenovirus expressing SARS coronavirus N protein.
Identifieur interne : 001830 ( PubMed/Corpus ); précédent : 001829; suivant : 001831Mouse studies of SARS coronavirus-specific immune responses to recombinant replication-defective adenovirus expressing SARS coronavirus N protein.
Auteurs : F W Y. Sin ; S C S. Cheng ; K T Chan ; L. Meng ; J. Yu ; Y. XieSource :
- Hong Kong medical journal = Xianggang yi xue za zhi [ 1024-2708 ] ; 2009.
English descriptors
- KwdEn :
- Adenoviridae (genetics), Animals, Antibody Formation, Female, Genetic Vectors, HLA-A2 Antigen (genetics), Humans, Mice, Mice, Inbred BALB C, Mice, Transgenic, Nucleocapsid Proteins (genetics), Nucleocapsid Proteins (immunology), SARS Virus (genetics), SARS Virus (immunology), Viral Vaccines (immunology).
- MESH :
- chemical , genetics : HLA-A2 Antigen, Nucleocapsid Proteins.
- genetics : Adenoviridae, SARS Virus.
- chemical , immunology : Nucleocapsid Proteins, SARS Virus, Viral Vaccines.
- Animals, Antibody Formation, Female, Genetic Vectors, Humans, Mice, Mice, Inbred BALB C, Mice, Transgenic.
Abstract
1. A recombinant adenovirus encoding SARS coronavirus(SARS-CoV) nucleocapsid protein (rAd-N) was constructed. 2. The ability of the rAd-N to induce anti-SARS-CoV N antibody production and cellular immune responses was evaluated in an HLA-A2.1/Kb transgenic mouse model.
PubMed: 19258632
Links to Exploration step
pubmed:19258632Le document en format XML
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<author><name sortKey="Sin, F W Y" sort="Sin, F W Y" uniqKey="Sin F" first="F W Y" last="Sin">F W Y. Sin</name>
<affiliation><nlm:affiliation>Department of Biology, The Hong Kong University of Science and Technology, Clear Water Bay, Kowloon, Hong Kong SAR, China.</nlm:affiliation>
</affiliation>
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<author><name sortKey="Cheng, S C S" sort="Cheng, S C S" uniqKey="Cheng S" first="S C S" last="Cheng">S C S. Cheng</name>
</author>
<author><name sortKey="Chan, K T" sort="Chan, K T" uniqKey="Chan K" first="K T" last="Chan">K T Chan</name>
</author>
<author><name sortKey="Meng, L" sort="Meng, L" uniqKey="Meng L" first="L" last="Meng">L. Meng</name>
</author>
<author><name sortKey="Yu, J" sort="Yu, J" uniqKey="Yu J" first="J" last="Yu">J. Yu</name>
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<author><name sortKey="Xie, Y" sort="Xie, Y" uniqKey="Xie Y" first="Y" last="Xie">Y. Xie</name>
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<sourceDesc><biblStruct><analytic><title xml:lang="en">Mouse studies of SARS coronavirus-specific immune responses to recombinant replication-defective adenovirus expressing SARS coronavirus N protein.</title>
<author><name sortKey="Sin, F W Y" sort="Sin, F W Y" uniqKey="Sin F" first="F W Y" last="Sin">F W Y. Sin</name>
<affiliation><nlm:affiliation>Department of Biology, The Hong Kong University of Science and Technology, Clear Water Bay, Kowloon, Hong Kong SAR, China.</nlm:affiliation>
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<author><name sortKey="Cheng, S C S" sort="Cheng, S C S" uniqKey="Cheng S" first="S C S" last="Cheng">S C S. Cheng</name>
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<author><name sortKey="Chan, K T" sort="Chan, K T" uniqKey="Chan K" first="K T" last="Chan">K T Chan</name>
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<author><name sortKey="Meng, L" sort="Meng, L" uniqKey="Meng L" first="L" last="Meng">L. Meng</name>
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<author><name sortKey="Yu, J" sort="Yu, J" uniqKey="Yu J" first="J" last="Yu">J. Yu</name>
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<author><name sortKey="Xie, Y" sort="Xie, Y" uniqKey="Xie Y" first="Y" last="Xie">Y. Xie</name>
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<series><title level="j">Hong Kong medical journal = Xianggang yi xue za zhi</title>
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<profileDesc><textClass><keywords scheme="KwdEn" xml:lang="en"><term>Adenoviridae (genetics)</term>
<term>Animals</term>
<term>Antibody Formation</term>
<term>Female</term>
<term>Genetic Vectors</term>
<term>HLA-A2 Antigen (genetics)</term>
<term>Humans</term>
<term>Mice</term>
<term>Mice, Inbred BALB C</term>
<term>Mice, Transgenic</term>
<term>Nucleocapsid Proteins (genetics)</term>
<term>Nucleocapsid Proteins (immunology)</term>
<term>SARS Virus (genetics)</term>
<term>SARS Virus (immunology)</term>
<term>Viral Vaccines (immunology)</term>
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<keywords scheme="MESH" type="chemical" qualifier="genetics" xml:lang="en"><term>HLA-A2 Antigen</term>
<term>Nucleocapsid Proteins</term>
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<keywords scheme="MESH" qualifier="genetics" xml:lang="en"><term>Adenoviridae</term>
<term>SARS Virus</term>
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<keywords scheme="MESH" type="chemical" qualifier="immunology" xml:lang="en"><term>Nucleocapsid Proteins</term>
<term>SARS Virus</term>
<term>Viral Vaccines</term>
</keywords>
<keywords scheme="MESH" xml:lang="en"><term>Animals</term>
<term>Antibody Formation</term>
<term>Female</term>
<term>Genetic Vectors</term>
<term>Humans</term>
<term>Mice</term>
<term>Mice, Inbred BALB C</term>
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<front><div type="abstract" xml:lang="en">1. A recombinant adenovirus encoding SARS coronavirus(SARS-CoV) nucleocapsid protein (rAd-N) was constructed. 2. The ability of the rAd-N to induce anti-SARS-CoV N antibody production and cellular immune responses was evaluated in an HLA-A2.1/Kb transgenic mouse model.</div>
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<DateRevised><Year>2016</Year>
<Month>10</Month>
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<JournalIssue CitedMedium="Internet"><Volume>15 Suppl 2</Volume>
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<Title>Hong Kong medical journal = Xianggang yi xue za zhi</Title>
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<ArticleTitle>Mouse studies of SARS coronavirus-specific immune responses to recombinant replication-defective adenovirus expressing SARS coronavirus N protein.</ArticleTitle>
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<Abstract><AbstractText>1. A recombinant adenovirus encoding SARS coronavirus(SARS-CoV) nucleocapsid protein (rAd-N) was constructed. 2. The ability of the rAd-N to induce anti-SARS-CoV N antibody production and cellular immune responses was evaluated in an HLA-A2.1/Kb transgenic mouse model.</AbstractText>
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<MeshHeadingList><MeshHeading><DescriptorName UI="D000256" MajorTopicYN="N">Adenoviridae</DescriptorName>
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<MeshHeading><DescriptorName UI="D005822" MajorTopicYN="N">Genetic Vectors</DescriptorName>
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