Serveur d'exploration SRAS

Attention, ce site est en cours de développement !
Attention, site généré par des moyens informatiques à partir de corpus bruts.
Les informations ne sont donc pas validées.

Mouse studies of SARS coronavirus-specific immune responses to recombinant replication-defective adenovirus expressing SARS coronavirus N protein.

Identifieur interne : 001835 ( PubMed/Checkpoint ); précédent : 001834; suivant : 001836

Mouse studies of SARS coronavirus-specific immune responses to recombinant replication-defective adenovirus expressing SARS coronavirus N protein.

Auteurs : F W Y. Sin [République populaire de Chine] ; S C S. Cheng ; K T Chan ; L. Meng ; J. Yu ; Y. Xie

Source :

RBID : pubmed:19258632

Descripteurs français

English descriptors

Abstract

1. A recombinant adenovirus encoding SARS coronavirus(SARS-CoV) nucleocapsid protein (rAd-N) was constructed. 2. The ability of the rAd-N to induce anti-SARS-CoV N antibody production and cellular immune responses was evaluated in an HLA-A2.1/Kb transgenic mouse model.

PubMed: 19258632


Affiliations:


Links toward previous steps (curation, corpus...)


Links to Exploration step

pubmed:19258632

Le document en format XML

<record>
<TEI>
<teiHeader>
<fileDesc>
<titleStmt>
<title xml:lang="en">Mouse studies of SARS coronavirus-specific immune responses to recombinant replication-defective adenovirus expressing SARS coronavirus N protein.</title>
<author>
<name sortKey="Sin, F W Y" sort="Sin, F W Y" uniqKey="Sin F" first="F W Y" last="Sin">F W Y. Sin</name>
<affiliation wicri:level="1">
<nlm:affiliation>Department of Biology, The Hong Kong University of Science and Technology, Clear Water Bay, Kowloon, Hong Kong SAR, China.</nlm:affiliation>
<country xml:lang="fr">République populaire de Chine</country>
<wicri:regionArea>Department of Biology, The Hong Kong University of Science and Technology, Clear Water Bay, Kowloon, Hong Kong SAR</wicri:regionArea>
<wicri:noRegion>Hong Kong SAR</wicri:noRegion>
</affiliation>
</author>
<author>
<name sortKey="Cheng, S C S" sort="Cheng, S C S" uniqKey="Cheng S" first="S C S" last="Cheng">S C S. Cheng</name>
</author>
<author>
<name sortKey="Chan, K T" sort="Chan, K T" uniqKey="Chan K" first="K T" last="Chan">K T Chan</name>
</author>
<author>
<name sortKey="Meng, L" sort="Meng, L" uniqKey="Meng L" first="L" last="Meng">L. Meng</name>
</author>
<author>
<name sortKey="Yu, J" sort="Yu, J" uniqKey="Yu J" first="J" last="Yu">J. Yu</name>
</author>
<author>
<name sortKey="Xie, Y" sort="Xie, Y" uniqKey="Xie Y" first="Y" last="Xie">Y. Xie</name>
</author>
</titleStmt>
<publicationStmt>
<idno type="wicri:source">PubMed</idno>
<date when="2009">2009</date>
<idno type="RBID">pubmed:19258632</idno>
<idno type="pmid">19258632</idno>
<idno type="wicri:Area/PubMed/Corpus">001830</idno>
<idno type="wicri:explorRef" wicri:stream="PubMed" wicri:step="Corpus" wicri:corpus="PubMed">001830</idno>
<idno type="wicri:Area/PubMed/Curation">001830</idno>
<idno type="wicri:explorRef" wicri:stream="PubMed" wicri:step="Curation">001830</idno>
<idno type="wicri:Area/PubMed/Checkpoint">001835</idno>
<idno type="wicri:explorRef" wicri:stream="Checkpoint" wicri:step="PubMed">001835</idno>
</publicationStmt>
<sourceDesc>
<biblStruct>
<analytic>
<title xml:lang="en">Mouse studies of SARS coronavirus-specific immune responses to recombinant replication-defective adenovirus expressing SARS coronavirus N protein.</title>
<author>
<name sortKey="Sin, F W Y" sort="Sin, F W Y" uniqKey="Sin F" first="F W Y" last="Sin">F W Y. Sin</name>
<affiliation wicri:level="1">
<nlm:affiliation>Department of Biology, The Hong Kong University of Science and Technology, Clear Water Bay, Kowloon, Hong Kong SAR, China.</nlm:affiliation>
<country xml:lang="fr">République populaire de Chine</country>
<wicri:regionArea>Department of Biology, The Hong Kong University of Science and Technology, Clear Water Bay, Kowloon, Hong Kong SAR</wicri:regionArea>
<wicri:noRegion>Hong Kong SAR</wicri:noRegion>
</affiliation>
</author>
<author>
<name sortKey="Cheng, S C S" sort="Cheng, S C S" uniqKey="Cheng S" first="S C S" last="Cheng">S C S. Cheng</name>
</author>
<author>
<name sortKey="Chan, K T" sort="Chan, K T" uniqKey="Chan K" first="K T" last="Chan">K T Chan</name>
</author>
<author>
<name sortKey="Meng, L" sort="Meng, L" uniqKey="Meng L" first="L" last="Meng">L. Meng</name>
</author>
<author>
<name sortKey="Yu, J" sort="Yu, J" uniqKey="Yu J" first="J" last="Yu">J. Yu</name>
</author>
<author>
<name sortKey="Xie, Y" sort="Xie, Y" uniqKey="Xie Y" first="Y" last="Xie">Y. Xie</name>
</author>
</analytic>
<series>
<title level="j">Hong Kong medical journal = Xianggang yi xue za zhi</title>
<idno type="ISSN">1024-2708</idno>
<imprint>
<date when="2009" type="published">2009</date>
</imprint>
</series>
</biblStruct>
</sourceDesc>
</fileDesc>
<profileDesc>
<textClass>
<keywords scheme="KwdEn" xml:lang="en">
<term>Adenoviridae (genetics)</term>
<term>Animals</term>
<term>Antibody Formation</term>
<term>Female</term>
<term>Genetic Vectors</term>
<term>HLA-A2 Antigen (genetics)</term>
<term>Humans</term>
<term>Mice</term>
<term>Mice, Inbred BALB C</term>
<term>Mice, Transgenic</term>
<term>Nucleocapsid Proteins (genetics)</term>
<term>Nucleocapsid Proteins (immunology)</term>
<term>SARS Virus (genetics)</term>
<term>SARS Virus (immunology)</term>
<term>Viral Vaccines (immunology)</term>
</keywords>
<keywords scheme="KwdFr" xml:lang="fr">
<term>Adenoviridae (génétique)</term>
<term>Animaux</term>
<term>Antigène HLA-A2 (génétique)</term>
<term>Femelle</term>
<term>Humains</term>
<term>Production d'anticorps</term>
<term>Protéines nucléocapside (génétique)</term>
<term>Protéines nucléocapside (immunologie)</term>
<term>Souris</term>
<term>Souris de lignée BALB C</term>
<term>Souris transgéniques</term>
<term>Vaccins antiviraux (immunologie)</term>
<term>Vecteurs génétiques</term>
<term>Virus du SRAS (génétique)</term>
<term>Virus du SRAS (immunologie)</term>
</keywords>
<keywords scheme="MESH" type="chemical" qualifier="genetics" xml:lang="en">
<term>HLA-A2 Antigen</term>
<term>Nucleocapsid Proteins</term>
</keywords>
<keywords scheme="MESH" qualifier="genetics" xml:lang="en">
<term>Adenoviridae</term>
<term>SARS Virus</term>
</keywords>
<keywords scheme="MESH" qualifier="génétique" xml:lang="fr">
<term>Adenoviridae</term>
<term>Antigène HLA-A2</term>
<term>Protéines nucléocapside</term>
<term>Virus du SRAS</term>
</keywords>
<keywords scheme="MESH" qualifier="immunologie" xml:lang="fr">
<term>Protéines nucléocapside</term>
<term>Vaccins antiviraux</term>
<term>Virus du SRAS</term>
</keywords>
<keywords scheme="MESH" type="chemical" qualifier="immunology" xml:lang="en">
<term>Nucleocapsid Proteins</term>
<term>SARS Virus</term>
<term>Viral Vaccines</term>
</keywords>
<keywords scheme="MESH" xml:lang="en">
<term>Animals</term>
<term>Antibody Formation</term>
<term>Female</term>
<term>Genetic Vectors</term>
<term>Humans</term>
<term>Mice</term>
<term>Mice, Inbred BALB C</term>
<term>Mice, Transgenic</term>
</keywords>
<keywords scheme="MESH" xml:lang="fr">
<term>Animaux</term>
<term>Femelle</term>
<term>Humains</term>
<term>Production d'anticorps</term>
<term>Souris</term>
<term>Souris de lignée BALB C</term>
<term>Souris transgéniques</term>
<term>Vecteurs génétiques</term>
</keywords>
</textClass>
</profileDesc>
</teiHeader>
<front>
<div type="abstract" xml:lang="en">1. A recombinant adenovirus encoding SARS coronavirus(SARS-CoV) nucleocapsid protein (rAd-N) was constructed. 2. The ability of the rAd-N to induce anti-SARS-CoV N antibody production and cellular immune responses was evaluated in an HLA-A2.1/Kb transgenic mouse model.</div>
</front>
</TEI>
<pubmed>
<MedlineCitation Status="MEDLINE" Owner="NLM">
<PMID Version="1">19258632</PMID>
<DateCompleted>
<Year>2009</Year>
<Month>12</Month>
<Day>21</Day>
</DateCompleted>
<DateRevised>
<Year>2016</Year>
<Month>10</Month>
<Day>20</Day>
</DateRevised>
<Article PubModel="Print">
<Journal>
<ISSN IssnType="Print">1024-2708</ISSN>
<JournalIssue CitedMedium="Internet">
<Volume>15 Suppl 2</Volume>
<PubDate>
<Year>2009</Year>
<Month>Feb</Month>
</PubDate>
</JournalIssue>
<Title>Hong Kong medical journal = Xianggang yi xue za zhi</Title>
<ISOAbbreviation>Hong Kong Med J</ISOAbbreviation>
</Journal>
<ArticleTitle>Mouse studies of SARS coronavirus-specific immune responses to recombinant replication-defective adenovirus expressing SARS coronavirus N protein.</ArticleTitle>
<Pagination>
<MedlinePgn>33-6</MedlinePgn>
</Pagination>
<Abstract>
<AbstractText>1. A recombinant adenovirus encoding SARS coronavirus(SARS-CoV) nucleocapsid protein (rAd-N) was constructed. 2. The ability of the rAd-N to induce anti-SARS-CoV N antibody production and cellular immune responses was evaluated in an HLA-A2.1/Kb transgenic mouse model.</AbstractText>
</Abstract>
<AuthorList CompleteYN="Y">
<Author ValidYN="Y">
<LastName>Sin</LastName>
<ForeName>F W Y</ForeName>
<Initials>FW</Initials>
<AffiliationInfo>
<Affiliation>Department of Biology, The Hong Kong University of Science and Technology, Clear Water Bay, Kowloon, Hong Kong SAR, China.</Affiliation>
</AffiliationInfo>
</Author>
<Author ValidYN="Y">
<LastName>Cheng</LastName>
<ForeName>S C S</ForeName>
<Initials>SC</Initials>
</Author>
<Author ValidYN="Y">
<LastName>Chan</LastName>
<ForeName>K T</ForeName>
<Initials>KT</Initials>
</Author>
<Author ValidYN="Y">
<LastName>Meng</LastName>
<ForeName>L</ForeName>
<Initials>L</Initials>
</Author>
<Author ValidYN="Y">
<LastName>Yu</LastName>
<ForeName>J</ForeName>
<Initials>J</Initials>
</Author>
<Author ValidYN="Y">
<LastName>Xie</LastName>
<ForeName>Y</ForeName>
<Initials>Y</Initials>
</Author>
</AuthorList>
<Language>eng</Language>
<PublicationTypeList>
<PublicationType UI="D016428">Journal Article</PublicationType>
<PublicationType UI="D013485">Research Support, Non-U.S. Gov't</PublicationType>
</PublicationTypeList>
</Article>
<MedlineJournalInfo>
<Country>China</Country>
<MedlineTA>Hong Kong Med J</MedlineTA>
<NlmUniqueID>9512509</NlmUniqueID>
<ISSNLinking>1024-2708</ISSNLinking>
</MedlineJournalInfo>
<ChemicalList>
<Chemical>
<RegistryNumber>0</RegistryNumber>
<NameOfSubstance UI="D015789">HLA-A2 Antigen</NameOfSubstance>
</Chemical>
<Chemical>
<RegistryNumber>0</RegistryNumber>
<NameOfSubstance UI="D019590">Nucleocapsid Proteins</NameOfSubstance>
</Chemical>
<Chemical>
<RegistryNumber>0</RegistryNumber>
<NameOfSubstance UI="D014765">Viral Vaccines</NameOfSubstance>
</Chemical>
<Chemical>
<RegistryNumber>0</RegistryNumber>
<NameOfSubstance UI="C099602">nucleocapsid protein, Coronavirus</NameOfSubstance>
</Chemical>
</ChemicalList>
<CitationSubset>IM</CitationSubset>
<MeshHeadingList>
<MeshHeading>
<DescriptorName UI="D000256" MajorTopicYN="N">Adenoviridae</DescriptorName>
<QualifierName UI="Q000235" MajorTopicYN="N">genetics</QualifierName>
</MeshHeading>
<MeshHeading>
<DescriptorName UI="D000818" MajorTopicYN="N">Animals</DescriptorName>
</MeshHeading>
<MeshHeading>
<DescriptorName UI="D000917" MajorTopicYN="N">Antibody Formation</DescriptorName>
</MeshHeading>
<MeshHeading>
<DescriptorName UI="D005260" MajorTopicYN="N">Female</DescriptorName>
</MeshHeading>
<MeshHeading>
<DescriptorName UI="D005822" MajorTopicYN="N">Genetic Vectors</DescriptorName>
</MeshHeading>
<MeshHeading>
<DescriptorName UI="D015789" MajorTopicYN="N">HLA-A2 Antigen</DescriptorName>
<QualifierName UI="Q000235" MajorTopicYN="Y">genetics</QualifierName>
</MeshHeading>
<MeshHeading>
<DescriptorName UI="D006801" MajorTopicYN="N">Humans</DescriptorName>
</MeshHeading>
<MeshHeading>
<DescriptorName UI="D051379" MajorTopicYN="N">Mice</DescriptorName>
</MeshHeading>
<MeshHeading>
<DescriptorName UI="D008807" MajorTopicYN="N">Mice, Inbred BALB C</DescriptorName>
</MeshHeading>
<MeshHeading>
<DescriptorName UI="D008822" MajorTopicYN="N">Mice, Transgenic</DescriptorName>
</MeshHeading>
<MeshHeading>
<DescriptorName UI="D019590" MajorTopicYN="N">Nucleocapsid Proteins</DescriptorName>
<QualifierName UI="Q000235" MajorTopicYN="N">genetics</QualifierName>
<QualifierName UI="Q000276" MajorTopicYN="Y">immunology</QualifierName>
</MeshHeading>
<MeshHeading>
<DescriptorName UI="D045473" MajorTopicYN="N">SARS Virus</DescriptorName>
<QualifierName UI="Q000235" MajorTopicYN="N">genetics</QualifierName>
<QualifierName UI="Q000276" MajorTopicYN="Y">immunology</QualifierName>
</MeshHeading>
<MeshHeading>
<DescriptorName UI="D014765" MajorTopicYN="N">Viral Vaccines</DescriptorName>
<QualifierName UI="Q000276" MajorTopicYN="Y">immunology</QualifierName>
</MeshHeading>
</MeshHeadingList>
</MedlineCitation>
<PubmedData>
<History>
<PubMedPubDate PubStatus="entrez">
<Year>2009</Year>
<Month>3</Month>
<Day>5</Day>
<Hour>9</Hour>
<Minute>0</Minute>
</PubMedPubDate>
<PubMedPubDate PubStatus="pubmed">
<Year>2009</Year>
<Month>9</Month>
<Day>23</Day>
<Hour>6</Hour>
<Minute>0</Minute>
</PubMedPubDate>
<PubMedPubDate PubStatus="medline">
<Year>2009</Year>
<Month>12</Month>
<Day>22</Day>
<Hour>6</Hour>
<Minute>0</Minute>
</PubMedPubDate>
</History>
<PublicationStatus>ppublish</PublicationStatus>
<ArticleIdList>
<ArticleId IdType="pubmed">19258632</ArticleId>
</ArticleIdList>
</PubmedData>
</pubmed>
<affiliations>
<list>
<country>
<li>République populaire de Chine</li>
</country>
</list>
<tree>
<noCountry>
<name sortKey="Chan, K T" sort="Chan, K T" uniqKey="Chan K" first="K T" last="Chan">K T Chan</name>
<name sortKey="Cheng, S C S" sort="Cheng, S C S" uniqKey="Cheng S" first="S C S" last="Cheng">S C S. Cheng</name>
<name sortKey="Meng, L" sort="Meng, L" uniqKey="Meng L" first="L" last="Meng">L. Meng</name>
<name sortKey="Xie, Y" sort="Xie, Y" uniqKey="Xie Y" first="Y" last="Xie">Y. Xie</name>
<name sortKey="Yu, J" sort="Yu, J" uniqKey="Yu J" first="J" last="Yu">J. Yu</name>
</noCountry>
<country name="République populaire de Chine">
<noRegion>
<name sortKey="Sin, F W Y" sort="Sin, F W Y" uniqKey="Sin F" first="F W Y" last="Sin">F W Y. Sin</name>
</noRegion>
</country>
</tree>
</affiliations>
</record>

Pour manipuler ce document sous Unix (Dilib)

EXPLOR_STEP=$WICRI_ROOT/Sante/explor/SrasV1/Data/PubMed/Checkpoint
HfdSelect -h $EXPLOR_STEP/biblio.hfd -nk 001835 | SxmlIndent | more

Ou

HfdSelect -h $EXPLOR_AREA/Data/PubMed/Checkpoint/biblio.hfd -nk 001835 | SxmlIndent | more

Pour mettre un lien sur cette page dans le réseau Wicri

{{Explor lien
   |wiki=    Sante
   |area=    SrasV1
   |flux=    PubMed
   |étape=   Checkpoint
   |type=    RBID
   |clé=     pubmed:19258632
   |texte=   Mouse studies of SARS coronavirus-specific immune responses to recombinant replication-defective adenovirus expressing SARS coronavirus N protein.
}}

Pour générer des pages wiki

HfdIndexSelect -h $EXPLOR_AREA/Data/PubMed/Checkpoint/RBID.i   -Sk "pubmed:19258632" \
       | HfdSelect -Kh $EXPLOR_AREA/Data/PubMed/Checkpoint/biblio.hfd   \
       | NlmPubMed2Wicri -a SrasV1 

Wicri

This area was generated with Dilib version V0.6.33.
Data generation: Tue Apr 28 14:49:16 2020. Site generation: Sat Mar 27 22:06:49 2021