Le SIDA en Afrique subsaharienne (serveur d'exploration)

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Cerebellar toxoplasmosis in HIV/AIDS: a case report.

Identifieur interne : 000C94 ( Ncbi/Curation ); précédent : 000C93; suivant : 000C95

Cerebellar toxoplasmosis in HIV/AIDS: a case report.

Auteurs : E U Emeka [Nigeria] ; A O Ogunrin ; A. Olubunmi

Source :

RBID : pubmed:20544640

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English descriptors

Abstract

Toxoplasma encephalitis is a common presentation of Toxoplasma gondii infection of the central nervous system in the late stage of human immunodeficiency viral (HIV) infection. The definitive diagnosis requires demonstration of toxoplasma in brain tissue. However, neuroradiologic demonstration (using Computed Tomography or Magnetic Resonance Imaging) of ring-enhanced multiple or single focal intracranial lesions in the presence of immunosuppression and prompt response to presumptive therapy are diagnostic in the absence of histological facilities. The rarity of toxoplasma lesions in the cerebellum prompts a high index of clinical suspicion and early institution of presumptive therapy in poor resource sub-Saharan countries like Nigeria.

PubMed: 20544640

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Le document en format XML

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<nlm:affiliation>Dermatology Unit, Department of Medicine, University of Benin Teaching Hospital, Benin City, Nigeria.</nlm:affiliation>
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<term>AIDS-Related Opportunistic Infections (complications)</term>
<term>AIDS-Related Opportunistic Infections (diagnosis)</term>
<term>AIDS-Related Opportunistic Infections (drug therapy)</term>
<term>Adult</term>
<term>Anti-Bacterial Agents (therapeutic use)</term>
<term>Central Nervous System Diseases (complications)</term>
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<term>Adulte</term>
<term>Antibactériens (usage thérapeutique)</term>
<term>Complexe vitaminique B (usage thérapeutique)</term>
<term>Humains</term>
<term>Infections opportunistes liées au SIDA ()</term>
<term>Infections opportunistes liées au SIDA (diagnostic)</term>
<term>Infections opportunistes liées au SIDA (traitement médicamenteux)</term>
<term>Infections à VIH ()</term>
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<term>Pyridoxine (usage thérapeutique)</term>
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<div type="abstract" xml:lang="en">Toxoplasma encephalitis is a common presentation of Toxoplasma gondii infection of the central nervous system in the late stage of human immunodeficiency viral (HIV) infection. The definitive diagnosis requires demonstration of toxoplasma in brain tissue. However, neuroradiologic demonstration (using Computed Tomography or Magnetic Resonance Imaging) of ring-enhanced multiple or single focal intracranial lesions in the presence of immunosuppression and prompt response to presumptive therapy are diagnostic in the absence of histological facilities. The rarity of toxoplasma lesions in the cerebellum prompts a high index of clinical suspicion and early institution of presumptive therapy in poor resource sub-Saharan countries like Nigeria.</div>
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