ParkinsonFranceV1, Main, Exploration, bibRecordById, pubmed:3434209

Motor neuron disease, parkinsonism and dementia

Identifieur interne : 005380 ( Main/Exploration ); précédent : 005379; suivant : 005381

Motor neuron disease, parkinsonism and dementia

Auteurs : M. B. Delisle [France] ; P. Gorce [France] ; E. Hirsch [France] ; J. J. Hauw [France] ; A. Rascol [France] ; H. Bouissou [France]

Source :

Acta Neuropathologica [ 0001-6322 ] ; 1987-01-01.

RBID : ISTEX:0E5F6C4B89C2B11462E419D6D051BC897918787E

Descripteurs français

Pascal (Inist)
- Anatomopathologie, Association, Démence, Homme, Inclusion cellulaire, Neurone moteur maladie, Parkinson maladie, Structure neurofibrillaire, Système nerveux pathologie.
Wicri :
- topic : Association, Homme.

English descriptors

KwdEn :
- Association, Brain (pathology), Brain (ultrastructure), Cell inclusion, Cytoplasmic Granules (ultrastructure), Dementia, Dementia (complications), Dementia (pathology), Human, Humans, Male, Microscopy, Electron, Middle Aged, Motor Neurons, Motor neuron disease, Nervous system diseases, Neurofibrillary tangle, Neuromuscular Diseases (complications), Neuromuscular Diseases (pathology), Parkinson Disease (complications), Parkinson Disease (pathology), Parkinson disease, Pathology, Spinal Cord (pathology), Spinal Cord (ultrastructure).
MESH :
- complications : Dementia, Neuromuscular Diseases, Parkinson Disease.
- pathology : Brain, Dementia, Neuromuscular Diseases, Parkinson Disease, Spinal Cord.
- ultrastructure : Brain, Cytoplasmic Granules, Spinal Cord.
- Humans, Male, Microscopy, Electron, Middle Aged, Motor Neurons.

Abstract

Summary: The clinicopathological finding in a 49-year-old man who presented multisystemic neurological degenerative disease are reported. The patient presented, at the age of 36, distal upper limb amyotrophy and 8 years later pyramidal signs with fasciculations. In his last year of life, he suffered extrapyramidal hypertonus and mental deterioration. Neuropathological examination showed anterior spinal root and cerebral atrophy. Myelin pallor was mild and predominated on posterior cords. Anterior horn neuronal loss was noted in the spinal cord as well as Alzheimer-type changes in the brain. Inclusion bodies consistent with Lewy bodies were diffusely apparent. The peculiar clinical progression in this case and the extension of neuropathological lesions with inclusion bodies mainly in the substantia nigra and cerebral cortex are an interesting subject of discussion.

Url:

https://api.istex.fr/document/0E5F6C4B89C2B11462E419D6D051BC897918787E/fulltext/pdf

DOI: 10.1007/BF00686799

Affiliations:

Le document en format XML

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<front><div type="abstract" xml:lang="en">Summary: The clinicopathological finding in a 49-year-old man who presented multisystemic neurological degenerative disease are reported. The patient presented, at the age of 36, distal upper limb amyotrophy and 8 years later pyramidal signs with fasciculations. In his last year of life, he suffered extrapyramidal hypertonus and mental deterioration. Neuropathological examination showed anterior spinal root and cerebral atrophy. Myelin pallor was mild and predominated on posterior cords. Anterior horn neuronal loss was noted in the spinal cord as well as Alzheimer-type changes in the brain. Inclusion bodies consistent with Lewy bodies were diffusely apparent. The peculiar clinical progression in this case and the extension of neuropathological lesions with inclusion bodies mainly in the substantia nigra and cerebral cortex are an interesting subject of discussion.</div>
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La maladie de Parkinson en France (serveur d'exploration)

Motor neuron disease, parkinsonism and dementia

Motor neuron disease, parkinsonism and dementia

Source :

Descripteurs français

English descriptors

Abstract

Links toward previous steps (curation, corpus...)

Le document en format XML

Pour manipuler ce document sous Unix (Dilib)

Pour mettre un lien sur cette page dans le réseau Wicri

	La maladie de Parkinson en France (serveur d'exploration)
	Attention, ce site est en cours de développement ! Attention, site généré par des moyens informatiques à partir de corpus bruts. Les informations ne sont donc pas validées.