La maladie de Parkinson en France (serveur d'exploration)

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Effect of bilateral stimulation of the subthalamic nucleus on parkinsonian dysarthria

Identifieur interne : 003265 ( Main/Curation ); précédent : 003264; suivant : 003266

Effect of bilateral stimulation of the subthalamic nucleus on parkinsonian dysarthria

Auteurs : Michèle Gentil [France] ; Serge Pinto [France] ; Pierre Pollak [France] ; Alim-Louis Benabid [France]

Source :

RBID : Pascal:03-0312009

Descripteurs français

English descriptors

Abstract

Never was the effect of bilateral stimulation of the subthalamic nucleus (STN) evaluated quantitatively on all the components of speech production, that is articulation, respiration and phonation, at the same time. It is the purpose of this study which uses force measurements of the articulatory organs and acoustic analysis in 16 parkinsonian patients. With STN stimulation, reaction and movement time of the articulatory organs decreased and their maximal strength, as well as their precision increased. We also noted a large beneficial effect on voice with a significant improvement in respiratory and phonatory functions.

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Pascal:03-0312009

Le document en format XML

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<orgName type="university">Université Joseph Fourier</orgName>
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<name sortKey="Pollak, Pierre" sort="Pollak, Pierre" uniqKey="Pollak P" first="Pierre" last="Pollak">Pierre Pollak</name>
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<addrLine>CHU Grenoble 38043 Grenoble Cedex 9</addrLine>
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<addrLine>BP 53 - 38041 Grenoble Cedex 9</addrLine>
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<addrLine>101, rue de Tolbiac, 75013 Paris </addrLine>
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<country>France</country>
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<orgName type="university">Université Joseph Fourier</orgName>
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<name sortKey="Benabid, Alim Louis" sort="Benabid, Alim Louis" uniqKey="Benabid A" first="Alim-Louis" last="Benabid">Alim-Louis Benabid</name>
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<orgName>Neurosciences précliniques</orgName>
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<addrLine>CHU Grenoble 38043 Grenoble Cedex 9</addrLine>
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<addrLine>BP 53 - 38041 Grenoble Cedex 9</addrLine>
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<orgName>Institut National de la Santé et de la Recherche Médicale</orgName>
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<addrLine>101, rue de Tolbiac, 75013 Paris </addrLine>
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</address>
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</desc>
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</hal:affiliation>
<country>France</country>
<placeName>
<settlement type="city">Grenoble</settlement>
<region type="region" nuts="2">Auvergne-Rhône-Alpes</region>
<region type="old region" nuts="2">Rhône-Alpes</region>
</placeName>
<orgName type="university">Université Joseph Fourier</orgName>
<orgName type="institution" wicri:auto="newGroup">Université de Grenoble</orgName>
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<idno type="DOI">10.1016/S0093-934X(02)00590-4</idno>
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<title level="j">Brain and Language</title>
<idno type="ISSN">0093-934X</idno>
<imprint>
<date type="datePub">2003</date>
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<keywords scheme="mix" xml:lang="en">
<term>Acoustic analysis</term>
<term>Parkinson's disease</term>
<term>Speech</term>
<term>Subthalamic stimulation</term>
<term>Surgical treatment</term>
<term>Voice</term>
</keywords>
<keywords scheme="Wicri" type="topic" xml:lang="fr">
<term>Discours</term>
</keywords>
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<front>
<div type="abstract" xml:lang="en">Never was the effect of bilateral stimulation of the subthalamic nucleus (STN) evaluated quantitatively on all the components of speech production, that is articulation, respiration and phonation, at the same time. It is the purpose of this study which uses force measurements of the articulatory organs and acoustic analysis in 16 parkinsonian patients. With STN stimulation, reaction and movement time of the articulatory organs decreased and their maximal strength, as well as their precision increased. We also noted a large beneficial effect on voice with a significant improvement in respiratory and phonatory functions.</div>
</front>
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