La maladie de Parkinson en France (serveur d'exploration)

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Effect of bilateral stimulation of the subthalamic nucleus on parkinsonian dysarthria.

Identifieur interne : 000329 ( Ncbi/Curation ); précédent : 000328; suivant : 000330

Effect of bilateral stimulation of the subthalamic nucleus on parkinsonian dysarthria.

Auteurs : Michèle Gentil [France] ; Serge Pinto ; Pierre Pollak ; Alim-Louis Benabid

Source :

RBID : pubmed:12735936

English descriptors

Abstract

Never was the effect of bilateral stimulation of the subthalamic nucleus (STN) evaluated quantitatively on all the components of speech production, that is articulation, respiration and phonation, at the same time. It is the purpose of this study which uses force measurements of the articulatory organs and acoustic analysis in 16 parkinsonian patients. With STN stimulation, reaction and movement time of the articulatory organs decreased and their maximal strength, as well as their precision increased. We also noted a large beneficial effect on voice with a significant improvement in respiratory and phonatory functions.

PubMed: 12735936

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pubmed:12735936

Le document en format XML

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<nlm:affiliation>Inserm, Unit 318, CHU, Service Neurologie, BP 217 38043, Grenoble cedex 9, France. mj.gentile@wanadoo.fr</nlm:affiliation>
<country xml:lang="fr">France</country>
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<region type="region" nuts="2">Auvergne-Rhône-Alpes</region>
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<name sortKey="Pollak, Pierre" sort="Pollak, Pierre" uniqKey="Pollak P" first="Pierre" last="Pollak">Pierre Pollak</name>
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<term>Adolescent</term>
<term>Dysarthria (diagnosis)</term>
<term>Dysarthria (etiology)</term>
<term>Dysarthria (therapy)</term>
<term>Electric Stimulation (instrumentation)</term>
<term>Electrodes, Implanted</term>
<term>Female</term>
<term>Functional Laterality (physiology)</term>
<term>Humans</term>
<term>Magnetic Resonance Imaging</term>
<term>Male</term>
<term>Middle Aged</term>
<term>Parkinson Disease (complications)</term>
<term>Severity of Illness Index</term>
<term>Sound Spectrography</term>
<term>Speech Acoustics</term>
<term>Speech Production Measurement</term>
<term>Subthalamic Nucleus (anatomy & histology)</term>
<term>Subthalamic Nucleus (physiology)</term>
<term>Voice Quality</term>
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<term>Subthalamic Nucleus</term>
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<term>Parkinson Disease</term>
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<keywords scheme="MESH" qualifier="diagnosis" xml:lang="en">
<term>Dysarthria</term>
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<term>Dysarthria</term>
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<term>Electric Stimulation</term>
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<term>Middle Aged</term>
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