Addiction in Parkinson's disease : Impact of subthalamic nucleus deep brain stimulation
Identifieur interne : 002D96 ( Main/Curation ); précédent : 002D95; suivant : 002D97Addiction in Parkinson's disease : Impact of subthalamic nucleus deep brain stimulation
Auteurs : Tatiana Witjas [France] ; Christelle Baunez [France] ; Jean Marc Henry [France] ; Marie Delfini [France] ; Jean Regis [France] ; André Ali Cherif [France] ; Jean Claude Peragut [France] ; Jean Philippe Azulay [France]Source :
- Movement disorders [ 0885-3185 ] ; 2005.
Descripteurs français
- Pascal (Inist)
English descriptors
- KwdEn :
- Addiction, Adult, Behavior, Addictive (complications), Behavior, Addictive (therapy), Clinical Protocols, Deep Brain Stimulation (methods), Deep brain stimulation, Dopamine, Drug of abuse, Dyskinesia, Humans, Male, Middle Aged, Nervous system diseases, Parkinson Disease (complications), Parkinson Disease (therapy), Parkinson disease, Subthalamic Nucleus (radiation effects), Subthalamic nucleus.
- MESH :
- complications : Behavior, Addictive, Parkinson Disease.
- methods : Deep Brain Stimulation.
- radiation effects : Subthalamic Nucleus.
- therapy : Behavior, Addictive, Parkinson Disease.
- Adult, Clinical Protocols, Humans, Male, Middle Aged.
Abstract
In Parkinson's disease, dopamine dysregulation syndrome (DDS) is characterized by severe dopamine addiction and behavioral disorders such as manic psychosis, hypersexuality, pathological gambling, and mood swings. Here, we describe the case of 2 young parkinsonian patients suffering from disabling motor fluctuations and dyskinesia associated with severe DDS. In addition to alleviating the motor disability in both patients, subthalamic nucleus (STN) deep brain stimulation greatly reduced the behavioral disorders as well as completely abolished the addiction to dopaminergic treatment. Dopaminergic addiction in patients with Parkinson's disease, therefore, does not constitute an obstacle to high-frequency STN stimulation, and this treatment may even cure the addiction.
Url:
Links toward previous steps (curation, corpus...)
- to stream PascalFrancis, to step Corpus: Pour aller vers cette notice dans l'étape Curation :000C42
- to stream PascalFrancis, to step Curation: Pour aller vers cette notice dans l'étape Curation :000792
- to stream PascalFrancis, to step Checkpoint: Pour aller vers cette notice dans l'étape Curation :000B56
- to stream Main, to step Merge: Pour aller vers cette notice dans l'étape Curation :003179
- to stream Hal, to step Corpus: Pour aller vers cette notice dans l'étape Curation :000053
- to stream Hal, to step Curation: Pour aller vers cette notice dans l'étape Curation :000053
- to stream Hal, to step Checkpoint: Pour aller vers cette notice dans l'étape Curation :000B22
- to stream Main, to step Merge: Pour aller vers cette notice dans l'étape Curation :003200
- to stream PubMed, to step Corpus: Pour aller vers cette notice dans l'étape Curation :000F35
- to stream PubMed, to step Curation: Pour aller vers cette notice dans l'étape Curation :000E95
- to stream PubMed, to step Checkpoint: Pour aller vers cette notice dans l'étape Curation :000E95
- to stream Ncbi, to step Merge: Pour aller vers cette notice dans l'étape Curation :000515
- to stream Ncbi, to step Curation: Pour aller vers cette notice dans l'étape Curation :000515
- to stream Ncbi, to step Checkpoint: Pour aller vers cette notice dans l'étape Curation :000515
- to stream Main, to step Merge: Pour aller vers cette notice dans l'étape Curation :002F59
Links to Exploration step
Pascal:05-0444034Le document en format XML
<record><TEI><teiHeader><fileDesc><titleStmt><title xml:lang="en" level="a">Addiction in Parkinson's disease : Impact of subthalamic nucleus deep brain stimulation</title><author><name sortKey="Witjas, Tatiana" sort="Witjas, Tatiana" uniqKey="Witjas T" first="Tatiana" last="Witjas">Tatiana Witjas</name><affiliation wicri:level="3"><inist:fA14 i1="01"><s1>Department of Neurology, University Hospital Timone</s1><s2>Marseille</s2><s3>FRA</s3><sZ>1 aut.</sZ><sZ>4 aut.</sZ><sZ>6 aut.</sZ><sZ>8 aut.</sZ></inist:fA14><country>France</country><placeName><region type="region">Provence-Alpes-Côte d'Azur</region><region type="old region">Provence-Alpes-Côte d'Azur</region><settlement type="city">Marseille</settlement></placeName></affiliation></author><author><name sortKey="Baunez, Christelle" sort="Baunez, Christelle" uniqKey="Baunez C" first="Christelle" last="Baunez">Christelle Baunez</name><affiliation wicri:level="3"><inist:fA14 i1="02"><s1>Laboratory of Neurobiology of Cognition, CNRS</s1><s2>Marseille</s2><s3>FRA</s3><sZ>2 aut.</sZ></inist:fA14><country>France</country><placeName><region type="region">Provence-Alpes-Côte d'Azur</region><region type="old region">Provence-Alpes-Côte d'Azur</region><settlement type="city">Marseille</settlement></placeName></affiliation></author><author><name sortKey="Henry, Jean Marc" sort="Henry, Jean Marc" uniqKey="Henry J" first="Jean Marc" last="Henry">Jean Marc Henry</name><affiliation wicri:level="3"><inist:fA14 i1="03"><s1>Department of Psychiatry, University Hospital Timone</s1><s2>Marseille</s2><s3>FRA</s3><sZ>3 aut.</sZ></inist:fA14><country>France</country><placeName><region type="region">Provence-Alpes-Côte d'Azur</region><region type="old region">Provence-Alpes-Côte d'Azur</region><settlement type="city">Marseille</settlement></placeName></affiliation></author><author><name sortKey="Delfini, Marie" sort="Delfini, Marie" uniqKey="Delfini M" first="Marie" last="Delfini">Marie Delfini</name><affiliation wicri:level="3"><inist:fA14 i1="01"><s1>Department of Neurology, University Hospital Timone</s1><s2>Marseille</s2><s3>FRA</s3><sZ>1 aut.</sZ><sZ>4 aut.</sZ><sZ>6 aut.</sZ><sZ>8 aut.</sZ></inist:fA14><country>France</country><placeName><region type="region">Provence-Alpes-Côte d'Azur</region><region type="old region">Provence-Alpes-Côte d'Azur</region><settlement type="city">Marseille</settlement></placeName></affiliation></author><author><name sortKey="Regis, Jean" sort="Regis, Jean" uniqKey="Regis J" first="Jean" last="Regis">Jean Regis</name><affiliation wicri:level="3"><inist:fA14 i1="04"><s1>Department of Functional and Stereotactic Neurosurgery, University Hospital Timone</s1><s2>Marseille</s2><s3>FRA</s3><sZ>5 aut.</sZ><sZ>7 aut.</sZ></inist:fA14><country>France</country><placeName><region type="region">Provence-Alpes-Côte d'Azur</region><region type="old region">Provence-Alpes-Côte d'Azur</region><settlement type="city">Marseille</settlement></placeName></affiliation></author><author><name sortKey="Cherif, Andre Ali" sort="Cherif, Andre Ali" uniqKey="Cherif A" first="André Ali" last="Cherif">André Ali Cherif</name><affiliation wicri:level="3"><inist:fA14 i1="01"><s1>Department of Neurology, University Hospital Timone</s1><s2>Marseille</s2><s3>FRA</s3><sZ>1 aut.</sZ><sZ>4 aut.</sZ><sZ>6 aut.</sZ><sZ>8 aut.</sZ></inist:fA14><country>France</country><placeName><region type="region">Provence-Alpes-Côte d'Azur</region><region type="old region">Provence-Alpes-Côte d'Azur</region><settlement type="city">Marseille</settlement></placeName></affiliation></author><author><name sortKey="Peragut, Jean Claude" sort="Peragut, Jean Claude" uniqKey="Peragut J" first="Jean Claude" last="Peragut">Jean Claude Peragut</name><affiliation wicri:level="3"><inist:fA14 i1="04"><s1>Department of Functional and Stereotactic Neurosurgery, University Hospital Timone</s1><s2>Marseille</s2><s3>FRA</s3><sZ>5 aut.</sZ><sZ>7 aut.</sZ></inist:fA14><country>France</country><placeName><region type="region">Provence-Alpes-Côte d'Azur</region><region type="old region">Provence-Alpes-Côte d'Azur</region><settlement type="city">Marseille</settlement></placeName></affiliation></author><author><name sortKey="Azulay, Jean Philippe" sort="Azulay, Jean Philippe" uniqKey="Azulay J" first="Jean Philippe" last="Azulay">Jean Philippe Azulay</name><affiliation wicri:level="3"><inist:fA14 i1="01"><s1>Department of Neurology, University Hospital Timone</s1><s2>Marseille</s2><s3>FRA</s3><sZ>1 aut.</sZ><sZ>4 aut.</sZ><sZ>6 aut.</sZ><sZ>8 aut.</sZ></inist:fA14><country>France</country><placeName><region type="region">Provence-Alpes-Côte d'Azur</region><region type="old region">Provence-Alpes-Côte d'Azur</region><settlement type="city">Marseille</settlement></placeName></affiliation></author></titleStmt><publicationStmt><idno type="wicri:source">INIST</idno><idno type="inist">05-0444034</idno><date when="2005">2005</date><idno type="stanalyst">PASCAL 05-0444034 INIST</idno><idno type="RBID">Pascal:05-0444034</idno><idno type="wicri:Area/PascalFrancis/Corpus">000C42</idno><idno type="wicri:Area/PascalFrancis/Curation">000792</idno><idno type="wicri:Area/PascalFrancis/Checkpoint">000B56</idno><idno type="wicri:explorRef" wicri:stream="PascalFrancis" wicri:step="Checkpoint">000B56</idno><idno type="wicri:doubleKey">0885-3185:2005:Witjas T:addiction:in:parkinson</idno><idno type="wicri:Area/Main/Merge">003179</idno><idno type="wicri:source">HAL</idno><idno type="RBID">Hal:hal-00093889</idno><idno type="url">https://hal.archives-ouvertes.fr/hal-00093889</idno><idno type="wicri:Area/Hal/Corpus">000053</idno><idno type="wicri:Area/Hal/Curation">000053</idno><idno type="wicri:Area/Hal/Checkpoint">000B22</idno><idno type="wicri:explorRef" wicri:stream="Hal" wicri:step="Checkpoint">000B22</idno><idno type="wicri:doubleKey">0885-3185:2005:Witjas T:addiction:in:parkinson</idno><idno type="wicri:Area/Main/Merge">003200</idno><idno type="wicri:source">PubMed</idno><idno type="RBID">pubmed:15858803</idno><idno type="wicri:Area/PubMed/Corpus">000F35</idno><idno type="wicri:explorRef" wicri:stream="PubMed" wicri:step="Corpus" wicri:corpus="PubMed">000F35</idno><idno type="wicri:Area/PubMed/Curation">000E95</idno><idno type="wicri:explorRef" wicri:stream="PubMed" wicri:step="Curation">000E95</idno><idno type="wicri:Area/PubMed/Checkpoint">000E95</idno><idno type="wicri:explorRef" wicri:stream="Checkpoint" wicri:step="PubMed">000E95</idno><idno type="wicri:Area/Ncbi/Merge">000515</idno><idno type="wicri:Area/Ncbi/Curation">000515</idno><idno type="wicri:Area/Ncbi/Checkpoint">000515</idno><idno type="wicri:doubleKey">0885-3185:2005:Witjas T:addiction:in:parkinson</idno><idno type="wicri:Area/Main/Merge">002F59</idno><idno type="wicri:Area/Main/Curation">002D96</idno></publicationStmt><sourceDesc><biblStruct><analytic><title xml:lang="en" level="a">Addiction in Parkinson's disease : Impact of subthalamic nucleus deep brain stimulation</title><author><name sortKey="Witjas, Tatiana" sort="Witjas, Tatiana" uniqKey="Witjas T" first="Tatiana" last="Witjas">Tatiana Witjas</name><affiliation wicri:level="3"><inist:fA14 i1="01"><s1>Department of Neurology, University Hospital Timone</s1><s2>Marseille</s2><s3>FRA</s3><sZ>1 aut.</sZ><sZ>4 aut.</sZ><sZ>6 aut.</sZ><sZ>8 aut.</sZ></inist:fA14><country>France</country><placeName><region type="region">Provence-Alpes-Côte d'Azur</region><region type="old region">Provence-Alpes-Côte d'Azur</region><settlement type="city">Marseille</settlement></placeName></affiliation></author><author><name sortKey="Baunez, Christelle" sort="Baunez, Christelle" uniqKey="Baunez C" first="Christelle" last="Baunez">Christelle Baunez</name><affiliation wicri:level="3"><inist:fA14 i1="02"><s1>Laboratory of Neurobiology of Cognition, CNRS</s1><s2>Marseille</s2><s3>FRA</s3><sZ>2 aut.</sZ></inist:fA14><country>France</country><placeName><region type="region">Provence-Alpes-Côte d'Azur</region><region type="old region">Provence-Alpes-Côte d'Azur</region><settlement type="city">Marseille</settlement></placeName></affiliation></author><author><name sortKey="Henry, Jean Marc" sort="Henry, Jean Marc" uniqKey="Henry J" first="Jean Marc" last="Henry">Jean Marc Henry</name><affiliation wicri:level="3"><inist:fA14 i1="03"><s1>Department of Psychiatry, University Hospital Timone</s1><s2>Marseille</s2><s3>FRA</s3><sZ>3 aut.</sZ></inist:fA14><country>France</country><placeName><region type="region">Provence-Alpes-Côte d'Azur</region><region type="old region">Provence-Alpes-Côte d'Azur</region><settlement type="city">Marseille</settlement></placeName></affiliation></author><author><name sortKey="Delfini, Marie" sort="Delfini, Marie" uniqKey="Delfini M" first="Marie" last="Delfini">Marie Delfini</name><affiliation wicri:level="3"><inist:fA14 i1="01"><s1>Department of Neurology, University Hospital Timone</s1><s2>Marseille</s2><s3>FRA</s3><sZ>1 aut.</sZ><sZ>4 aut.</sZ><sZ>6 aut.</sZ><sZ>8 aut.</sZ></inist:fA14><country>France</country><placeName><region type="region">Provence-Alpes-Côte d'Azur</region><region type="old region">Provence-Alpes-Côte d'Azur</region><settlement type="city">Marseille</settlement></placeName></affiliation></author><author><name sortKey="Regis, Jean" sort="Regis, Jean" uniqKey="Regis J" first="Jean" last="Regis">Jean Regis</name><affiliation wicri:level="3"><inist:fA14 i1="04"><s1>Department of Functional and Stereotactic Neurosurgery, University Hospital Timone</s1><s2>Marseille</s2><s3>FRA</s3><sZ>5 aut.</sZ><sZ>7 aut.</sZ></inist:fA14><country>France</country><placeName><region type="region">Provence-Alpes-Côte d'Azur</region><region type="old region">Provence-Alpes-Côte d'Azur</region><settlement type="city">Marseille</settlement></placeName></affiliation></author><author><name sortKey="Cherif, Andre Ali" sort="Cherif, Andre Ali" uniqKey="Cherif A" first="André Ali" last="Cherif">André Ali Cherif</name><affiliation wicri:level="3"><inist:fA14 i1="01"><s1>Department of Neurology, University Hospital Timone</s1><s2>Marseille</s2><s3>FRA</s3><sZ>1 aut.</sZ><sZ>4 aut.</sZ><sZ>6 aut.</sZ><sZ>8 aut.</sZ></inist:fA14><country>France</country><placeName><region type="region">Provence-Alpes-Côte d'Azur</region><region type="old region">Provence-Alpes-Côte d'Azur</region><settlement type="city">Marseille</settlement></placeName></affiliation></author><author><name sortKey="Peragut, Jean Claude" sort="Peragut, Jean Claude" uniqKey="Peragut J" first="Jean Claude" last="Peragut">Jean Claude Peragut</name><affiliation wicri:level="3"><inist:fA14 i1="04"><s1>Department of Functional and Stereotactic Neurosurgery, University Hospital Timone</s1><s2>Marseille</s2><s3>FRA</s3><sZ>5 aut.</sZ><sZ>7 aut.</sZ></inist:fA14><country>France</country><placeName><region type="region">Provence-Alpes-Côte d'Azur</region><region type="old region">Provence-Alpes-Côte d'Azur</region><settlement type="city">Marseille</settlement></placeName></affiliation></author><author><name sortKey="Azulay, Jean Philippe" sort="Azulay, Jean Philippe" uniqKey="Azulay J" first="Jean Philippe" last="Azulay">Jean Philippe Azulay</name><affiliation wicri:level="3"><inist:fA14 i1="01"><s1>Department of Neurology, University Hospital Timone</s1><s2>Marseille</s2><s3>FRA</s3><sZ>1 aut.</sZ><sZ>4 aut.</sZ><sZ>6 aut.</sZ><sZ>8 aut.</sZ></inist:fA14><country>France</country><placeName><region type="region">Provence-Alpes-Côte d'Azur</region><region type="old region">Provence-Alpes-Côte d'Azur</region><settlement type="city">Marseille</settlement></placeName></affiliation></author></analytic><series><title level="j" type="main">Movement disorders</title><title level="j" type="abbreviated">Mov. disord.</title><idno type="ISSN">0885-3185</idno><imprint><date when="2005">2005</date></imprint></series></biblStruct></sourceDesc><seriesStmt><title level="j" type="main">Movement disorders</title><title level="j" type="abbreviated">Mov. disord.</title><idno type="ISSN">0885-3185</idno></seriesStmt></fileDesc><profileDesc><textClass><keywords scheme="KwdEn" xml:lang="en"><term>Addiction</term><term>Adult</term><term>Behavior, Addictive (complications)</term><term>Behavior, Addictive (therapy)</term><term>Clinical Protocols</term><term>Deep Brain Stimulation (methods)</term><term>Deep brain stimulation</term><term>Dopamine</term><term>Drug of abuse</term><term>Dyskinesia</term><term>Humans</term><term>Male</term><term>Middle Aged</term><term>Nervous system diseases</term><term>Parkinson Disease (complications)</term><term>Parkinson Disease (therapy)</term><term>Parkinson disease</term><term>Subthalamic Nucleus (radiation effects)</term><term>Subthalamic nucleus</term></keywords><keywords scheme="MESH" qualifier="complications" xml:lang="en"><term>Behavior, Addictive</term><term>Parkinson Disease</term></keywords><keywords scheme="MESH" qualifier="methods" xml:lang="en"><term>Deep Brain Stimulation</term></keywords><keywords scheme="MESH" qualifier="radiation effects" xml:lang="en"><term>Subthalamic Nucleus</term></keywords><keywords scheme="MESH" qualifier="therapy" xml:lang="en"><term>Behavior, Addictive</term><term>Parkinson Disease</term></keywords><keywords scheme="MESH" xml:lang="en"><term>Adult</term><term>Clinical Protocols</term><term>Humans</term><term>Male</term><term>Middle Aged</term></keywords><keywords scheme="Pascal" xml:lang="fr"><term>Système nerveux pathologie</term><term>Addiction</term><term>Parkinson maladie</term><term>Dyskinésie</term><term>Substance toxicomanogène</term><term>Noyau sousthalamique</term><term>Dopamine</term><term>Stimulation cérébrale profonde</term></keywords></textClass></profileDesc></teiHeader><front><div type="abstract" xml:lang="en">In Parkinson's disease, dopamine dysregulation syndrome (DDS) is characterized by severe dopamine addiction and behavioral disorders such as manic psychosis, hypersexuality, pathological gambling, and mood swings. Here, we describe the case of 2 young parkinsonian patients suffering from disabling motor fluctuations and dyskinesia associated with severe DDS. In addition to alleviating the motor disability in both patients, subthalamic nucleus (STN) deep brain stimulation greatly reduced the behavioral disorders as well as completely abolished the addiction to dopaminergic treatment. Dopaminergic addiction in patients with Parkinson's disease, therefore, does not constitute an obstacle to high-frequency STN stimulation, and this treatment may even cure the addiction.</div></front></TEI><double idat="0885-3185:2005:Witjas T:addiction:in:parkinson"><HAL><TEI><teiHeader><fileDesc><titleStmt><title xml:lang="en">Addiction in Parkinson's disease: Impact of subthalamic nucleus deep brain stimulation.</title><author><name sortKey="Witjas, T" sort="Witjas, T" uniqKey="Witjas T" first="T." last="Witjas">T. Witjas</name><affiliation wicri:level="1"><hal:affiliation type="laboratory" xml:id="struct-199398" status="VALID"><idno type="RNSR">201220268H</idno><orgName>Laboratoire de Neurosciences Cognitives</orgName><orgName type="acronym">LNC</orgName><date type="start">2012</date><desc><address><addrLine>Pole 3 C Case C 3 Place Victor Hugo 13331 Marseille Cedex 3</addrLine><country key="FR"></country></address><ref type="url">http://lnc.univ-amu.fr/</ref></desc><listRelation><relation name="UMR7291" active="#struct-441569" type="direct"></relation><relation name="UMR7291" active="#struct-198056" type="direct"></relation><relation name="UMR6155" active="#struct-92823" type="direct"></relation></listRelation><tutelles><tutelle name="UMR7291" active="#struct-441569" type="direct"><org type="institution" xml:id="struct-441569" status="VALID"><idno type="IdRef">02636817X</idno><idno type="ISNI">0000000122597504</idno><orgName>Centre National de la Recherche Scientifique</orgName><orgName type="acronym">CNRS</orgName><date type="start">1939-10-19</date><desc><address><country key="FR"></country></address><ref type="url">http://www.cnrs.fr/</ref></desc></org></tutelle><tutelle name="UMR7291" active="#struct-198056" type="direct"><org type="institution" xml:id="struct-198056" status="VALID"><idno type="IdRef">15863621X</idno><idno type="ISNI">0000 0001 2176 4817</idno><orgName>Aix Marseille Université</orgName><orgName type="acronym">AMU</orgName><date type="start">2012-01-01</date><desc><address><addrLine>Aix-Marseille UniversitéJardins du Pharo58 Boulevard Charles Livon13284 Marseille cedex 7</addrLine><country key="FR"></country></address><ref type="url">http://www.univ-amu.fr/</ref></desc></org></tutelle><tutelle name="UMR6155" active="#struct-92823" type="direct"><org type="institution" xml:id="struct-92823" status="OLD"><idno type="IdRef">026403781</idno><orgName>Université de Provence - Aix-Marseille 1</orgName><date type="end">2011-12-31</date><desc><address><addrLine>3, place Victor Hugo - 13331 Marseille Cedex 03</addrLine><country key="FR"></country></address><ref type="url">http://www.univ-provence.fr/</ref></desc></org></tutelle></tutelles></hal:affiliation><country>France</country><placeName><settlement type="city">Marseille</settlement><region type="region" nuts="2">Provence-Alpes-Côte d'Azur</region></placeName><orgName type="university">Université d'Aix-Marseille</orgName></affiliation></author><author><name sortKey="Baunez, C" sort="Baunez, C" uniqKey="Baunez C" first="C." last="Baunez">C. Baunez</name><affiliation wicri:level="1"><hal:affiliation type="laboratory" xml:id="struct-199398" status="VALID"><idno type="RNSR">201220268H</idno><orgName>Laboratoire de Neurosciences Cognitives</orgName><orgName type="acronym">LNC</orgName><date type="start">2012</date><desc><address><addrLine>Pole 3 C Case C 3 Place Victor Hugo 13331 Marseille Cedex 3</addrLine><country key="FR"></country></address><ref type="url">http://lnc.univ-amu.fr/</ref></desc><listRelation><relation name="UMR7291" active="#struct-441569" type="direct"></relation><relation name="UMR7291" active="#struct-198056" type="direct"></relation><relation name="UMR6155" active="#struct-92823" type="direct"></relation></listRelation><tutelles><tutelle name="UMR7291" active="#struct-441569" type="direct"><org type="institution" xml:id="struct-441569" status="VALID"><idno type="IdRef">02636817X</idno><idno type="ISNI">0000000122597504</idno><orgName>Centre National de la Recherche Scientifique</orgName><orgName type="acronym">CNRS</orgName><date type="start">1939-10-19</date><desc><address><country key="FR"></country></address><ref type="url">http://www.cnrs.fr/</ref></desc></org></tutelle><tutelle name="UMR7291" active="#struct-198056" type="direct"><org type="institution" xml:id="struct-198056" status="VALID"><idno type="IdRef">15863621X</idno><idno type="ISNI">0000 0001 2176 4817</idno><orgName>Aix Marseille Université</orgName><orgName type="acronym">AMU</orgName><date type="start">2012-01-01</date><desc><address><addrLine>Aix-Marseille UniversitéJardins du Pharo58 Boulevard Charles Livon13284 Marseille cedex 7</addrLine><country key="FR"></country></address><ref type="url">http://www.univ-amu.fr/</ref></desc></org></tutelle><tutelle name="UMR6155" active="#struct-92823" type="direct"><org type="institution" xml:id="struct-92823" status="OLD"><idno type="IdRef">026403781</idno><orgName>Université de Provence - Aix-Marseille 1</orgName><date type="end">2011-12-31</date><desc><address><addrLine>3, place Victor Hugo - 13331 Marseille Cedex 03</addrLine><country key="FR"></country></address><ref type="url">http://www.univ-provence.fr/</ref></desc></org></tutelle></tutelles></hal:affiliation><country>France</country><placeName><settlement type="city">Marseille</settlement><region type="region" nuts="2">Provence-Alpes-Côte d'Azur</region></placeName><orgName type="university">Université d'Aix-Marseille</orgName></affiliation></author><author><name sortKey="J M, Henry" sort="J M, Henry" uniqKey="J M H" first="Henry" last="J. M.">Henry J. M.</name><affiliation wicri:level="1"><hal:affiliation type="laboratory" xml:id="struct-199398" status="VALID"><idno type="RNSR">201220268H</idno><orgName>Laboratoire de Neurosciences Cognitives</orgName><orgName type="acronym">LNC</orgName><date type="start">2012</date><desc><address><addrLine>Pole 3 C Case C 3 Place Victor Hugo 13331 Marseille Cedex 3</addrLine><country key="FR"></country></address><ref type="url">http://lnc.univ-amu.fr/</ref></desc><listRelation><relation name="UMR7291" active="#struct-441569" type="direct"></relation><relation name="UMR7291" active="#struct-198056" type="direct"></relation><relation name="UMR6155" active="#struct-92823" type="direct"></relation></listRelation><tutelles><tutelle name="UMR7291" active="#struct-441569" type="direct"><org type="institution" xml:id="struct-441569" status="VALID"><idno type="IdRef">02636817X</idno><idno type="ISNI">0000000122597504</idno><orgName>Centre National de la Recherche Scientifique</orgName><orgName type="acronym">CNRS</orgName><date type="start">1939-10-19</date><desc><address><country key="FR"></country></address><ref type="url">http://www.cnrs.fr/</ref></desc></org></tutelle><tutelle name="UMR7291" active="#struct-198056" type="direct"><org type="institution" xml:id="struct-198056" status="VALID"><idno type="IdRef">15863621X</idno><idno type="ISNI">0000 0001 2176 4817</idno><orgName>Aix Marseille Université</orgName><orgName type="acronym">AMU</orgName><date type="start">2012-01-01</date><desc><address><addrLine>Aix-Marseille UniversitéJardins du Pharo58 Boulevard Charles Livon13284 Marseille cedex 7</addrLine><country key="FR"></country></address><ref type="url">http://www.univ-amu.fr/</ref></desc></org></tutelle><tutelle name="UMR6155" active="#struct-92823" type="direct"><org type="institution" xml:id="struct-92823" status="OLD"><idno type="IdRef">026403781</idno><orgName>Université de Provence - Aix-Marseille 1</orgName><date type="end">2011-12-31</date><desc><address><addrLine>3, place Victor Hugo - 13331 Marseille Cedex 03</addrLine><country key="FR"></country></address><ref type="url">http://www.univ-provence.fr/</ref></desc></org></tutelle></tutelles></hal:affiliation><country>France</country><placeName><settlement type="city">Marseille</settlement><region type="region" nuts="2">Provence-Alpes-Côte d'Azur</region></placeName><orgName type="university">Université d'Aix-Marseille</orgName></affiliation></author><author><name sortKey="Delfini, M" sort="Delfini, M" uniqKey="Delfini M" first="M." last="Delfini">M. Delfini</name><affiliation wicri:level="1"><hal:affiliation type="laboratory" xml:id="struct-199398" status="VALID"><idno type="RNSR">201220268H</idno><orgName>Laboratoire de Neurosciences Cognitives</orgName><orgName type="acronym">LNC</orgName><date type="start">2012</date><desc><address><addrLine>Pole 3 C Case C 3 Place Victor Hugo 13331 Marseille Cedex 3</addrLine><country key="FR"></country></address><ref type="url">http://lnc.univ-amu.fr/</ref></desc><listRelation><relation name="UMR7291" active="#struct-441569" type="direct"></relation><relation name="UMR7291" active="#struct-198056" type="direct"></relation><relation name="UMR6155" active="#struct-92823" type="direct"></relation></listRelation><tutelles><tutelle name="UMR7291" active="#struct-441569" type="direct"><org type="institution" xml:id="struct-441569" status="VALID"><idno type="IdRef">02636817X</idno><idno type="ISNI">0000000122597504</idno><orgName>Centre National de la Recherche Scientifique</orgName><orgName type="acronym">CNRS</orgName><date type="start">1939-10-19</date><desc><address><country key="FR"></country></address><ref type="url">http://www.cnrs.fr/</ref></desc></org></tutelle><tutelle name="UMR7291" active="#struct-198056" type="direct"><org type="institution" xml:id="struct-198056" status="VALID"><idno type="IdRef">15863621X</idno><idno type="ISNI">0000 0001 2176 4817</idno><orgName>Aix Marseille Université</orgName><orgName type="acronym">AMU</orgName><date type="start">2012-01-01</date><desc><address><addrLine>Aix-Marseille UniversitéJardins du Pharo58 Boulevard Charles Livon13284 Marseille cedex 7</addrLine><country key="FR"></country></address><ref type="url">http://www.univ-amu.fr/</ref></desc></org></tutelle><tutelle name="UMR6155" active="#struct-92823" type="direct"><org type="institution" xml:id="struct-92823" status="OLD"><idno type="IdRef">026403781</idno><orgName>Université de Provence - Aix-Marseille 1</orgName><date type="end">2011-12-31</date><desc><address><addrLine>3, place Victor Hugo - 13331 Marseille Cedex 03</addrLine><country key="FR"></country></address><ref type="url">http://www.univ-provence.fr/</ref></desc></org></tutelle></tutelles></hal:affiliation><country>France</country><placeName><settlement type="city">Marseille</settlement><region type="region" nuts="2">Provence-Alpes-Côte d'Azur</region></placeName><orgName type="university">Université d'Aix-Marseille</orgName></affiliation></author><author><name sortKey="Regis, J" sort="Regis, J" uniqKey="Regis J" first="J." last="Regis">J. Regis</name><affiliation wicri:level="1"><hal:affiliation type="laboratory" xml:id="struct-199398" status="VALID"><idno type="RNSR">201220268H</idno><orgName>Laboratoire de Neurosciences Cognitives</orgName><orgName type="acronym">LNC</orgName><date type="start">2012</date><desc><address><addrLine>Pole 3 C Case C 3 Place Victor Hugo 13331 Marseille Cedex 3</addrLine><country key="FR"></country></address><ref type="url">http://lnc.univ-amu.fr/</ref></desc><listRelation><relation name="UMR7291" active="#struct-441569" type="direct"></relation><relation name="UMR7291" active="#struct-198056" type="direct"></relation><relation name="UMR6155" active="#struct-92823" type="direct"></relation></listRelation><tutelles><tutelle name="UMR7291" active="#struct-441569" type="direct"><org type="institution" xml:id="struct-441569" status="VALID"><idno type="IdRef">02636817X</idno><idno type="ISNI">0000000122597504</idno><orgName>Centre National de la Recherche Scientifique</orgName><orgName type="acronym">CNRS</orgName><date type="start">1939-10-19</date><desc><address><country key="FR"></country></address><ref type="url">http://www.cnrs.fr/</ref></desc></org></tutelle><tutelle name="UMR7291" active="#struct-198056" type="direct"><org type="institution" xml:id="struct-198056" status="VALID"><idno type="IdRef">15863621X</idno><idno type="ISNI">0000 0001 2176 4817</idno><orgName>Aix Marseille Université</orgName><orgName type="acronym">AMU</orgName><date type="start">2012-01-01</date><desc><address><addrLine>Aix-Marseille UniversitéJardins du Pharo58 Boulevard Charles Livon13284 Marseille cedex 7</addrLine><country key="FR"></country></address><ref type="url">http://www.univ-amu.fr/</ref></desc></org></tutelle><tutelle name="UMR6155" active="#struct-92823" type="direct"><org type="institution" xml:id="struct-92823" status="OLD"><idno type="IdRef">026403781</idno><orgName>Université de Provence - Aix-Marseille 1</orgName><date type="end">2011-12-31</date><desc><address><addrLine>3, place Victor Hugo - 13331 Marseille Cedex 03</addrLine><country key="FR"></country></address><ref type="url">http://www.univ-provence.fr/</ref></desc></org></tutelle></tutelles></hal:affiliation><country>France</country><placeName><settlement type="city">Marseille</settlement><region type="region" nuts="2">Provence-Alpes-Côte d'Azur</region></placeName><orgName type="university">Université d'Aix-Marseille</orgName></affiliation></author><author><name sortKey="Cherif A, Ali" sort="Cherif A, Ali" uniqKey="Cherif A A" first="Ali" last="Cherif A.">Ali Cherif A.</name><affiliation wicri:level="1"><hal:affiliation type="laboratory" xml:id="struct-199398" status="VALID"><idno type="RNSR">201220268H</idno><orgName>Laboratoire de Neurosciences Cognitives</orgName><orgName type="acronym">LNC</orgName><date type="start">2012</date><desc><address><addrLine>Pole 3 C Case C 3 Place Victor Hugo 13331 Marseille Cedex 3</addrLine><country key="FR"></country></address><ref type="url">http://lnc.univ-amu.fr/</ref></desc><listRelation><relation name="UMR7291" active="#struct-441569" type="direct"></relation><relation name="UMR7291" active="#struct-198056" type="direct"></relation><relation name="UMR6155" active="#struct-92823" type="direct"></relation></listRelation><tutelles><tutelle name="UMR7291" active="#struct-441569" type="direct"><org type="institution" xml:id="struct-441569" status="VALID"><idno type="IdRef">02636817X</idno><idno type="ISNI">0000000122597504</idno><orgName>Centre National de la Recherche Scientifique</orgName><orgName type="acronym">CNRS</orgName><date type="start">1939-10-19</date><desc><address><country key="FR"></country></address><ref type="url">http://www.cnrs.fr/</ref></desc></org></tutelle><tutelle name="UMR7291" active="#struct-198056" type="direct"><org type="institution" xml:id="struct-198056" status="VALID"><idno type="IdRef">15863621X</idno><idno type="ISNI">0000 0001 2176 4817</idno><orgName>Aix Marseille Université</orgName><orgName type="acronym">AMU</orgName><date type="start">2012-01-01</date><desc><address><addrLine>Aix-Marseille UniversitéJardins du Pharo58 Boulevard Charles Livon13284 Marseille cedex 7</addrLine><country key="FR"></country></address><ref type="url">http://www.univ-amu.fr/</ref></desc></org></tutelle><tutelle name="UMR6155" active="#struct-92823" type="direct"><org type="institution" xml:id="struct-92823" status="OLD"><idno type="IdRef">026403781</idno><orgName>Université de Provence - Aix-Marseille 1</orgName><date type="end">2011-12-31</date><desc><address><addrLine>3, place Victor Hugo - 13331 Marseille Cedex 03</addrLine><country key="FR"></country></address><ref type="url">http://www.univ-provence.fr/</ref></desc></org></tutelle></tutelles></hal:affiliation><country>France</country><placeName><settlement type="city">Marseille</settlement><region type="region" nuts="2">Provence-Alpes-Côte d'Azur</region></placeName><orgName type="university">Université d'Aix-Marseille</orgName></affiliation></author><author><name sortKey="J C, Peragut" sort="J C, Peragut" uniqKey="J C P" first="Peragut" last="J. C.">Peragut J. C.</name><affiliation wicri:level="1"><hal:affiliation type="laboratory" xml:id="struct-199398" status="VALID"><idno type="RNSR">201220268H</idno><orgName>Laboratoire de Neurosciences Cognitives</orgName><orgName type="acronym">LNC</orgName><date type="start">2012</date><desc><address><addrLine>Pole 3 C Case C 3 Place Victor Hugo 13331 Marseille Cedex 3</addrLine><country key="FR"></country></address><ref type="url">http://lnc.univ-amu.fr/</ref></desc><listRelation><relation name="UMR7291" active="#struct-441569" type="direct"></relation><relation name="UMR7291" active="#struct-198056" type="direct"></relation><relation name="UMR6155" active="#struct-92823" type="direct"></relation></listRelation><tutelles><tutelle name="UMR7291" active="#struct-441569" type="direct"><org type="institution" xml:id="struct-441569" status="VALID"><idno type="IdRef">02636817X</idno><idno type="ISNI">0000000122597504</idno><orgName>Centre National de la Recherche Scientifique</orgName><orgName type="acronym">CNRS</orgName><date type="start">1939-10-19</date><desc><address><country key="FR"></country></address><ref type="url">http://www.cnrs.fr/</ref></desc></org></tutelle><tutelle name="UMR7291" active="#struct-198056" type="direct"><org type="institution" xml:id="struct-198056" status="VALID"><idno type="IdRef">15863621X</idno><idno type="ISNI">0000 0001 2176 4817</idno><orgName>Aix Marseille Université</orgName><orgName type="acronym">AMU</orgName><date type="start">2012-01-01</date><desc><address><addrLine>Aix-Marseille UniversitéJardins du Pharo58 Boulevard Charles Livon13284 Marseille cedex 7</addrLine><country key="FR"></country></address><ref type="url">http://www.univ-amu.fr/</ref></desc></org></tutelle><tutelle name="UMR6155" active="#struct-92823" type="direct"><org type="institution" xml:id="struct-92823" status="OLD"><idno type="IdRef">026403781</idno><orgName>Université de Provence - Aix-Marseille 1</orgName><date type="end">2011-12-31</date><desc><address><addrLine>3, place Victor Hugo - 13331 Marseille Cedex 03</addrLine><country key="FR"></country></address><ref type="url">http://www.univ-provence.fr/</ref></desc></org></tutelle></tutelles></hal:affiliation><country>France</country><placeName><settlement type="city">Marseille</settlement><region type="region" nuts="2">Provence-Alpes-Côte d'Azur</region></placeName><orgName type="university">Université d'Aix-Marseille</orgName></affiliation></author><author><name sortKey="J P, Azulay" sort="J P, Azulay" uniqKey="J P A" first="Azulay" last="J. P.">Azulay J. P.</name><affiliation wicri:level="1"><hal:affiliation type="laboratory" xml:id="struct-199398" status="VALID"><idno type="RNSR">201220268H</idno><orgName>Laboratoire de Neurosciences Cognitives</orgName><orgName type="acronym">LNC</orgName><date type="start">2012</date><desc><address><addrLine>Pole 3 C Case C 3 Place Victor Hugo 13331 Marseille Cedex 3</addrLine><country key="FR"></country></address><ref type="url">http://lnc.univ-amu.fr/</ref></desc><listRelation><relation name="UMR7291" active="#struct-441569" type="direct"></relation><relation name="UMR7291" active="#struct-198056" type="direct"></relation><relation name="UMR6155" active="#struct-92823" type="direct"></relation></listRelation><tutelles><tutelle name="UMR7291" active="#struct-441569" type="direct"><org type="institution" xml:id="struct-441569" status="VALID"><idno type="IdRef">02636817X</idno><idno type="ISNI">0000000122597504</idno><orgName>Centre National de la Recherche Scientifique</orgName><orgName type="acronym">CNRS</orgName><date type="start">1939-10-19</date><desc><address><country key="FR"></country></address><ref type="url">http://www.cnrs.fr/</ref></desc></org></tutelle><tutelle name="UMR7291" active="#struct-198056" type="direct"><org type="institution" xml:id="struct-198056" status="VALID"><idno type="IdRef">15863621X</idno><idno type="ISNI">0000 0001 2176 4817</idno><orgName>Aix Marseille Université</orgName><orgName type="acronym">AMU</orgName><date type="start">2012-01-01</date><desc><address><addrLine>Aix-Marseille UniversitéJardins du Pharo58 Boulevard Charles Livon13284 Marseille cedex 7</addrLine><country key="FR"></country></address><ref type="url">http://www.univ-amu.fr/</ref></desc></org></tutelle><tutelle name="UMR6155" active="#struct-92823" type="direct"><org type="institution" xml:id="struct-92823" status="OLD"><idno type="IdRef">026403781</idno><orgName>Université de Provence - Aix-Marseille 1</orgName><date type="end">2011-12-31</date><desc><address><addrLine>3, place Victor Hugo - 13331 Marseille Cedex 03</addrLine><country key="FR"></country></address><ref type="url">http://www.univ-provence.fr/</ref></desc></org></tutelle></tutelles></hal:affiliation><country>France</country><placeName><settlement type="city">Marseille</settlement><region type="region" nuts="2">Provence-Alpes-Côte d'Azur</region></placeName><orgName type="university">Université d'Aix-Marseille</orgName></affiliation></author></titleStmt><publicationStmt><idno type="wicri:source">HAL</idno><idno type="RBID">Hal:hal-00093889</idno><idno type="halId">hal-00093889</idno><idno type="halUri">https://hal.archives-ouvertes.fr/hal-00093889</idno><idno type="url">https://hal.archives-ouvertes.fr/hal-00093889</idno><date when="2005">2005</date><idno type="wicri:Area/Hal/Corpus">000053</idno><idno type="wicri:Area/Hal/Curation">000053</idno><idno type="wicri:Area/Hal/Checkpoint">000B22</idno><idno type="wicri:explorRef" wicri:stream="Hal" wicri:step="Checkpoint">000B22</idno><idno type="wicri:doubleKey">0885-3185:2005:Witjas T:addiction:in:parkinson</idno><idno type="wicri:Area/Main/Merge">003200</idno></publicationStmt><sourceDesc><biblStruct><analytic><title xml:lang="en">Addiction in Parkinson's disease: Impact of subthalamic nucleus deep brain stimulation.</title><author><name sortKey="Witjas, T" sort="Witjas, T" uniqKey="Witjas T" first="T." last="Witjas">T. Witjas</name><affiliation wicri:level="1"><hal:affiliation type="laboratory" xml:id="struct-199398" status="VALID"><idno type="RNSR">201220268H</idno><orgName>Laboratoire de Neurosciences Cognitives</orgName><orgName type="acronym">LNC</orgName><date type="start">2012</date><desc><address><addrLine>Pole 3 C Case C 3 Place Victor Hugo 13331 Marseille Cedex 3</addrLine><country key="FR"></country></address><ref type="url">http://lnc.univ-amu.fr/</ref></desc><listRelation><relation name="UMR7291" active="#struct-441569" type="direct"></relation><relation name="UMR7291" active="#struct-198056" type="direct"></relation><relation name="UMR6155" active="#struct-92823" type="direct"></relation></listRelation><tutelles><tutelle name="UMR7291" active="#struct-441569" type="direct"><org type="institution" xml:id="struct-441569" status="VALID"><idno type="IdRef">02636817X</idno><idno type="ISNI">0000000122597504</idno><orgName>Centre National de la Recherche Scientifique</orgName><orgName type="acronym">CNRS</orgName><date type="start">1939-10-19</date><desc><address><country key="FR"></country></address><ref type="url">http://www.cnrs.fr/</ref></desc></org></tutelle><tutelle name="UMR7291" active="#struct-198056" type="direct"><org type="institution" xml:id="struct-198056" status="VALID"><idno type="IdRef">15863621X</idno><idno type="ISNI">0000 0001 2176 4817</idno><orgName>Aix Marseille Université</orgName><orgName type="acronym">AMU</orgName><date type="start">2012-01-01</date><desc><address><addrLine>Aix-Marseille UniversitéJardins du Pharo58 Boulevard Charles Livon13284 Marseille cedex 7</addrLine><country key="FR"></country></address><ref type="url">http://www.univ-amu.fr/</ref></desc></org></tutelle><tutelle name="UMR6155" active="#struct-92823" type="direct"><org type="institution" xml:id="struct-92823" status="OLD"><idno type="IdRef">026403781</idno><orgName>Université de Provence - Aix-Marseille 1</orgName><date type="end">2011-12-31</date><desc><address><addrLine>3, place Victor Hugo - 13331 Marseille Cedex 03</addrLine><country key="FR"></country></address><ref type="url">http://www.univ-provence.fr/</ref></desc></org></tutelle></tutelles></hal:affiliation><country>France</country><placeName><settlement type="city">Marseille</settlement><region type="region" nuts="2">Provence-Alpes-Côte d'Azur</region></placeName><orgName type="university">Université d'Aix-Marseille</orgName></affiliation></author><author><name sortKey="Baunez, C" sort="Baunez, C" uniqKey="Baunez C" first="C." last="Baunez">C. Baunez</name><affiliation wicri:level="1"><hal:affiliation type="laboratory" xml:id="struct-199398" status="VALID"><idno type="RNSR">201220268H</idno><orgName>Laboratoire de Neurosciences Cognitives</orgName><orgName type="acronym">LNC</orgName><date type="start">2012</date><desc><address><addrLine>Pole 3 C Case C 3 Place Victor Hugo 13331 Marseille Cedex 3</addrLine><country key="FR"></country></address><ref type="url">http://lnc.univ-amu.fr/</ref></desc><listRelation><relation name="UMR7291" active="#struct-441569" type="direct"></relation><relation name="UMR7291" active="#struct-198056" type="direct"></relation><relation name="UMR6155" active="#struct-92823" type="direct"></relation></listRelation><tutelles><tutelle name="UMR7291" active="#struct-441569" type="direct"><org type="institution" xml:id="struct-441569" status="VALID"><idno type="IdRef">02636817X</idno><idno type="ISNI">0000000122597504</idno><orgName>Centre National de la Recherche Scientifique</orgName><orgName type="acronym">CNRS</orgName><date type="start">1939-10-19</date><desc><address><country key="FR"></country></address><ref type="url">http://www.cnrs.fr/</ref></desc></org></tutelle><tutelle name="UMR7291" active="#struct-198056" type="direct"><org type="institution" xml:id="struct-198056" status="VALID"><idno type="IdRef">15863621X</idno><idno type="ISNI">0000 0001 2176 4817</idno><orgName>Aix Marseille Université</orgName><orgName type="acronym">AMU</orgName><date type="start">2012-01-01</date><desc><address><addrLine>Aix-Marseille UniversitéJardins du Pharo58 Boulevard Charles Livon13284 Marseille cedex 7</addrLine><country key="FR"></country></address><ref type="url">http://www.univ-amu.fr/</ref></desc></org></tutelle><tutelle name="UMR6155" active="#struct-92823" type="direct"><org type="institution" xml:id="struct-92823" status="OLD"><idno type="IdRef">026403781</idno><orgName>Université de Provence - Aix-Marseille 1</orgName><date type="end">2011-12-31</date><desc><address><addrLine>3, place Victor Hugo - 13331 Marseille Cedex 03</addrLine><country key="FR"></country></address><ref type="url">http://www.univ-provence.fr/</ref></desc></org></tutelle></tutelles></hal:affiliation><country>France</country><placeName><settlement type="city">Marseille</settlement><region type="region" nuts="2">Provence-Alpes-Côte d'Azur</region></placeName><orgName type="university">Université d'Aix-Marseille</orgName></affiliation></author><author><name sortKey="J M, Henry" sort="J M, Henry" uniqKey="J M H" first="Henry" last="J. M.">Henry J. M.</name><affiliation wicri:level="1"><hal:affiliation type="laboratory" xml:id="struct-199398" status="VALID"><idno type="RNSR">201220268H</idno><orgName>Laboratoire de Neurosciences Cognitives</orgName><orgName type="acronym">LNC</orgName><date type="start">2012</date><desc><address><addrLine>Pole 3 C Case C 3 Place Victor Hugo 13331 Marseille Cedex 3</addrLine><country key="FR"></country></address><ref type="url">http://lnc.univ-amu.fr/</ref></desc><listRelation><relation name="UMR7291" active="#struct-441569" type="direct"></relation><relation name="UMR7291" active="#struct-198056" type="direct"></relation><relation name="UMR6155" active="#struct-92823" type="direct"></relation></listRelation><tutelles><tutelle name="UMR7291" active="#struct-441569" type="direct"><org type="institution" xml:id="struct-441569" status="VALID"><idno type="IdRef">02636817X</idno><idno type="ISNI">0000000122597504</idno><orgName>Centre National de la Recherche Scientifique</orgName><orgName type="acronym">CNRS</orgName><date type="start">1939-10-19</date><desc><address><country key="FR"></country></address><ref type="url">http://www.cnrs.fr/</ref></desc></org></tutelle><tutelle name="UMR7291" active="#struct-198056" type="direct"><org type="institution" xml:id="struct-198056" status="VALID"><idno type="IdRef">15863621X</idno><idno type="ISNI">0000 0001 2176 4817</idno><orgName>Aix Marseille Université</orgName><orgName type="acronym">AMU</orgName><date type="start">2012-01-01</date><desc><address><addrLine>Aix-Marseille UniversitéJardins du Pharo58 Boulevard Charles Livon13284 Marseille cedex 7</addrLine><country key="FR"></country></address><ref type="url">http://www.univ-amu.fr/</ref></desc></org></tutelle><tutelle name="UMR6155" active="#struct-92823" type="direct"><org type="institution" xml:id="struct-92823" status="OLD"><idno type="IdRef">026403781</idno><orgName>Université de Provence - Aix-Marseille 1</orgName><date type="end">2011-12-31</date><desc><address><addrLine>3, place Victor Hugo - 13331 Marseille Cedex 03</addrLine><country key="FR"></country></address><ref type="url">http://www.univ-provence.fr/</ref></desc></org></tutelle></tutelles></hal:affiliation><country>France</country><placeName><settlement type="city">Marseille</settlement><region type="region" nuts="2">Provence-Alpes-Côte d'Azur</region></placeName><orgName type="university">Université d'Aix-Marseille</orgName></affiliation></author><author><name sortKey="Delfini, M" sort="Delfini, M" uniqKey="Delfini M" first="M." last="Delfini">M. Delfini</name><affiliation wicri:level="1"><hal:affiliation type="laboratory" xml:id="struct-199398" status="VALID"><idno type="RNSR">201220268H</idno><orgName>Laboratoire de Neurosciences Cognitives</orgName><orgName type="acronym">LNC</orgName><date type="start">2012</date><desc><address><addrLine>Pole 3 C Case C 3 Place Victor Hugo 13331 Marseille Cedex 3</addrLine><country key="FR"></country></address><ref type="url">http://lnc.univ-amu.fr/</ref></desc><listRelation><relation name="UMR7291" active="#struct-441569" type="direct"></relation><relation name="UMR7291" active="#struct-198056" type="direct"></relation><relation name="UMR6155" active="#struct-92823" type="direct"></relation></listRelation><tutelles><tutelle name="UMR7291" active="#struct-441569" type="direct"><org type="institution" xml:id="struct-441569" status="VALID"><idno type="IdRef">02636817X</idno><idno type="ISNI">0000000122597504</idno><orgName>Centre National de la Recherche Scientifique</orgName><orgName type="acronym">CNRS</orgName><date type="start">1939-10-19</date><desc><address><country key="FR"></country></address><ref type="url">http://www.cnrs.fr/</ref></desc></org></tutelle><tutelle name="UMR7291" active="#struct-198056" type="direct"><org type="institution" xml:id="struct-198056" status="VALID"><idno type="IdRef">15863621X</idno><idno type="ISNI">0000 0001 2176 4817</idno><orgName>Aix Marseille Université</orgName><orgName type="acronym">AMU</orgName><date type="start">2012-01-01</date><desc><address><addrLine>Aix-Marseille UniversitéJardins du Pharo58 Boulevard Charles Livon13284 Marseille cedex 7</addrLine><country key="FR"></country></address><ref type="url">http://www.univ-amu.fr/</ref></desc></org></tutelle><tutelle name="UMR6155" active="#struct-92823" type="direct"><org type="institution" xml:id="struct-92823" status="OLD"><idno type="IdRef">026403781</idno><orgName>Université de Provence - Aix-Marseille 1</orgName><date type="end">2011-12-31</date><desc><address><addrLine>3, place Victor Hugo - 13331 Marseille Cedex 03</addrLine><country key="FR"></country></address><ref type="url">http://www.univ-provence.fr/</ref></desc></org></tutelle></tutelles></hal:affiliation><country>France</country><placeName><settlement type="city">Marseille</settlement><region type="region" nuts="2">Provence-Alpes-Côte d'Azur</region></placeName><orgName type="university">Université d'Aix-Marseille</orgName></affiliation></author><author><name sortKey="Regis, J" sort="Regis, J" uniqKey="Regis J" first="J." last="Regis">J. Regis</name><affiliation wicri:level="1"><hal:affiliation type="laboratory" xml:id="struct-199398" status="VALID"><idno type="RNSR">201220268H</idno><orgName>Laboratoire de Neurosciences Cognitives</orgName><orgName type="acronym">LNC</orgName><date type="start">2012</date><desc><address><addrLine>Pole 3 C Case C 3 Place Victor Hugo 13331 Marseille Cedex 3</addrLine><country key="FR"></country></address><ref type="url">http://lnc.univ-amu.fr/</ref></desc><listRelation><relation name="UMR7291" active="#struct-441569" type="direct"></relation><relation name="UMR7291" active="#struct-198056" type="direct"></relation><relation name="UMR6155" active="#struct-92823" type="direct"></relation></listRelation><tutelles><tutelle name="UMR7291" active="#struct-441569" type="direct"><org type="institution" xml:id="struct-441569" status="VALID"><idno type="IdRef">02636817X</idno><idno type="ISNI">0000000122597504</idno><orgName>Centre National de la Recherche Scientifique</orgName><orgName type="acronym">CNRS</orgName><date type="start">1939-10-19</date><desc><address><country key="FR"></country></address><ref type="url">http://www.cnrs.fr/</ref></desc></org></tutelle><tutelle name="UMR7291" active="#struct-198056" type="direct"><org type="institution" xml:id="struct-198056" status="VALID"><idno type="IdRef">15863621X</idno><idno type="ISNI">0000 0001 2176 4817</idno><orgName>Aix Marseille Université</orgName><orgName type="acronym">AMU</orgName><date type="start">2012-01-01</date><desc><address><addrLine>Aix-Marseille UniversitéJardins du Pharo58 Boulevard Charles Livon13284 Marseille cedex 7</addrLine><country key="FR"></country></address><ref type="url">http://www.univ-amu.fr/</ref></desc></org></tutelle><tutelle name="UMR6155" active="#struct-92823" type="direct"><org type="institution" xml:id="struct-92823" status="OLD"><idno type="IdRef">026403781</idno><orgName>Université de Provence - Aix-Marseille 1</orgName><date type="end">2011-12-31</date><desc><address><addrLine>3, place Victor Hugo - 13331 Marseille Cedex 03</addrLine><country key="FR"></country></address><ref type="url">http://www.univ-provence.fr/</ref></desc></org></tutelle></tutelles></hal:affiliation><country>France</country><placeName><settlement type="city">Marseille</settlement><region type="region" nuts="2">Provence-Alpes-Côte d'Azur</region></placeName><orgName type="university">Université d'Aix-Marseille</orgName></affiliation></author><author><name sortKey="Cherif A, Ali" sort="Cherif A, Ali" uniqKey="Cherif A A" first="Ali" last="Cherif A.">Ali Cherif A.</name><affiliation wicri:level="1"><hal:affiliation type="laboratory" xml:id="struct-199398" status="VALID"><idno type="RNSR">201220268H</idno><orgName>Laboratoire de Neurosciences Cognitives</orgName><orgName type="acronym">LNC</orgName><date type="start">2012</date><desc><address><addrLine>Pole 3 C Case C 3 Place Victor Hugo 13331 Marseille Cedex 3</addrLine><country key="FR"></country></address><ref type="url">http://lnc.univ-amu.fr/</ref></desc><listRelation><relation name="UMR7291" active="#struct-441569" type="direct"></relation><relation name="UMR7291" active="#struct-198056" type="direct"></relation><relation name="UMR6155" active="#struct-92823" type="direct"></relation></listRelation><tutelles><tutelle name="UMR7291" active="#struct-441569" type="direct"><org type="institution" xml:id="struct-441569" status="VALID"><idno type="IdRef">02636817X</idno><idno type="ISNI">0000000122597504</idno><orgName>Centre National de la Recherche Scientifique</orgName><orgName type="acronym">CNRS</orgName><date type="start">1939-10-19</date><desc><address><country key="FR"></country></address><ref type="url">http://www.cnrs.fr/</ref></desc></org></tutelle><tutelle name="UMR7291" active="#struct-198056" type="direct"><org type="institution" xml:id="struct-198056" status="VALID"><idno type="IdRef">15863621X</idno><idno type="ISNI">0000 0001 2176 4817</idno><orgName>Aix Marseille Université</orgName><orgName type="acronym">AMU</orgName><date type="start">2012-01-01</date><desc><address><addrLine>Aix-Marseille UniversitéJardins du Pharo58 Boulevard Charles Livon13284 Marseille cedex 7</addrLine><country key="FR"></country></address><ref type="url">http://www.univ-amu.fr/</ref></desc></org></tutelle><tutelle name="UMR6155" active="#struct-92823" type="direct"><org type="institution" xml:id="struct-92823" status="OLD"><idno type="IdRef">026403781</idno><orgName>Université de Provence - Aix-Marseille 1</orgName><date type="end">2011-12-31</date><desc><address><addrLine>3, place Victor Hugo - 13331 Marseille Cedex 03</addrLine><country key="FR"></country></address><ref type="url">http://www.univ-provence.fr/</ref></desc></org></tutelle></tutelles></hal:affiliation><country>France</country><placeName><settlement type="city">Marseille</settlement><region type="region" nuts="2">Provence-Alpes-Côte d'Azur</region></placeName><orgName type="university">Université d'Aix-Marseille</orgName></affiliation></author><author><name sortKey="J C, Peragut" sort="J C, Peragut" uniqKey="J C P" first="Peragut" last="J. C.">Peragut J. C.</name><affiliation wicri:level="1"><hal:affiliation type="laboratory" xml:id="struct-199398" status="VALID"><idno type="RNSR">201220268H</idno><orgName>Laboratoire de Neurosciences Cognitives</orgName><orgName type="acronym">LNC</orgName><date type="start">2012</date><desc><address><addrLine>Pole 3 C Case C 3 Place Victor Hugo 13331 Marseille Cedex 3</addrLine><country key="FR"></country></address><ref type="url">http://lnc.univ-amu.fr/</ref></desc><listRelation><relation name="UMR7291" active="#struct-441569" type="direct"></relation><relation name="UMR7291" active="#struct-198056" type="direct"></relation><relation name="UMR6155" active="#struct-92823" type="direct"></relation></listRelation><tutelles><tutelle name="UMR7291" active="#struct-441569" type="direct"><org type="institution" xml:id="struct-441569" status="VALID"><idno type="IdRef">02636817X</idno><idno type="ISNI">0000000122597504</idno><orgName>Centre National de la Recherche Scientifique</orgName><orgName type="acronym">CNRS</orgName><date type="start">1939-10-19</date><desc><address><country key="FR"></country></address><ref type="url">http://www.cnrs.fr/</ref></desc></org></tutelle><tutelle name="UMR7291" active="#struct-198056" type="direct"><org type="institution" xml:id="struct-198056" status="VALID"><idno type="IdRef">15863621X</idno><idno type="ISNI">0000 0001 2176 4817</idno><orgName>Aix Marseille Université</orgName><orgName type="acronym">AMU</orgName><date type="start">2012-01-01</date><desc><address><addrLine>Aix-Marseille UniversitéJardins du Pharo58 Boulevard Charles Livon13284 Marseille cedex 7</addrLine><country key="FR"></country></address><ref type="url">http://www.univ-amu.fr/</ref></desc></org></tutelle><tutelle name="UMR6155" active="#struct-92823" type="direct"><org type="institution" xml:id="struct-92823" status="OLD"><idno type="IdRef">026403781</idno><orgName>Université de Provence - Aix-Marseille 1</orgName><date type="end">2011-12-31</date><desc><address><addrLine>3, place Victor Hugo - 13331 Marseille Cedex 03</addrLine><country key="FR"></country></address><ref type="url">http://www.univ-provence.fr/</ref></desc></org></tutelle></tutelles></hal:affiliation><country>France</country><placeName><settlement type="city">Marseille</settlement><region type="region" nuts="2">Provence-Alpes-Côte d'Azur</region></placeName><orgName type="university">Université d'Aix-Marseille</orgName></affiliation></author><author><name sortKey="J P, Azulay" sort="J P, Azulay" uniqKey="J P A" first="Azulay" last="J. P.">Azulay J. P.</name><affiliation wicri:level="1"><hal:affiliation type="laboratory" xml:id="struct-199398" status="VALID"><idno type="RNSR">201220268H</idno><orgName>Laboratoire de Neurosciences Cognitives</orgName><orgName type="acronym">LNC</orgName><date type="start">2012</date><desc><address><addrLine>Pole 3 C Case C 3 Place Victor Hugo 13331 Marseille Cedex 3</addrLine><country key="FR"></country></address><ref type="url">http://lnc.univ-amu.fr/</ref></desc><listRelation><relation name="UMR7291" active="#struct-441569" type="direct"></relation><relation name="UMR7291" active="#struct-198056" type="direct"></relation><relation name="UMR6155" active="#struct-92823" type="direct"></relation></listRelation><tutelles><tutelle name="UMR7291" active="#struct-441569" type="direct"><org type="institution" xml:id="struct-441569" status="VALID"><idno type="IdRef">02636817X</idno><idno type="ISNI">0000000122597504</idno><orgName>Centre National de la Recherche Scientifique</orgName><orgName type="acronym">CNRS</orgName><date type="start">1939-10-19</date><desc><address><country key="FR"></country></address><ref type="url">http://www.cnrs.fr/</ref></desc></org></tutelle><tutelle name="UMR7291" active="#struct-198056" type="direct"><org type="institution" xml:id="struct-198056" status="VALID"><idno type="IdRef">15863621X</idno><idno type="ISNI">0000 0001 2176 4817</idno><orgName>Aix Marseille Université</orgName><orgName type="acronym">AMU</orgName><date type="start">2012-01-01</date><desc><address><addrLine>Aix-Marseille UniversitéJardins du Pharo58 Boulevard Charles Livon13284 Marseille cedex 7</addrLine><country key="FR"></country></address><ref type="url">http://www.univ-amu.fr/</ref></desc></org></tutelle><tutelle name="UMR6155" active="#struct-92823" type="direct"><org type="institution" xml:id="struct-92823" status="OLD"><idno type="IdRef">026403781</idno><orgName>Université de Provence - Aix-Marseille 1</orgName><date type="end">2011-12-31</date><desc><address><addrLine>3, place Victor Hugo - 13331 Marseille Cedex 03</addrLine><country key="FR"></country></address><ref type="url">http://www.univ-provence.fr/</ref></desc></org></tutelle></tutelles></hal:affiliation><country>France</country><placeName><settlement type="city">Marseille</settlement><region type="region" nuts="2">Provence-Alpes-Côte d'Azur</region></placeName><orgName type="university">Université d'Aix-Marseille</orgName></affiliation></author></analytic><series><title level="j">Movement Disorders</title><idno type="ISSN">0885-3185</idno><imprint><date type="datePub">2005</date></imprint></series></biblStruct></sourceDesc></fileDesc><profileDesc><textClass></textClass></profileDesc></teiHeader></TEI></HAL><INIST><TEI><teiHeader><fileDesc><titleStmt><title xml:lang="en" level="a">Addiction in Parkinson's disease : Impact of subthalamic nucleus deep brain stimulation</title><author><name sortKey="Witjas, Tatiana" sort="Witjas, Tatiana" uniqKey="Witjas T" first="Tatiana" last="Witjas">Tatiana Witjas</name><affiliation wicri:level="3"><inist:fA14 i1="01"><s1>Department of Neurology, University Hospital Timone</s1><s2>Marseille</s2><s3>FRA</s3><sZ>1 aut.</sZ><sZ>4 aut.</sZ><sZ>6 aut.</sZ><sZ>8 aut.</sZ></inist:fA14><country>France</country><placeName><region type="region">Provence-Alpes-Côte d'Azur</region><region type="old region">Provence-Alpes-Côte d'Azur</region><settlement type="city">Marseille</settlement></placeName></affiliation></author><author><name sortKey="Baunez, Christelle" sort="Baunez, Christelle" uniqKey="Baunez C" first="Christelle" last="Baunez">Christelle Baunez</name><affiliation wicri:level="3"><inist:fA14 i1="02"><s1>Laboratory of Neurobiology of Cognition, CNRS</s1><s2>Marseille</s2><s3>FRA</s3><sZ>2 aut.</sZ></inist:fA14><country>France</country><placeName><region type="region">Provence-Alpes-Côte d'Azur</region><region type="old region">Provence-Alpes-Côte d'Azur</region><settlement type="city">Marseille</settlement></placeName></affiliation></author><author><name sortKey="Henry, Jean Marc" sort="Henry, Jean Marc" uniqKey="Henry J" first="Jean Marc" last="Henry">Jean Marc Henry</name><affiliation wicri:level="3"><inist:fA14 i1="03"><s1>Department of Psychiatry, University Hospital Timone</s1><s2>Marseille</s2><s3>FRA</s3><sZ>3 aut.</sZ></inist:fA14><country>France</country><placeName><region type="region">Provence-Alpes-Côte d'Azur</region><region type="old region">Provence-Alpes-Côte d'Azur</region><settlement type="city">Marseille</settlement></placeName></affiliation></author><author><name sortKey="Delfini, Marie" sort="Delfini, Marie" uniqKey="Delfini M" first="Marie" last="Delfini">Marie Delfini</name><affiliation wicri:level="3"><inist:fA14 i1="01"><s1>Department of Neurology, University Hospital Timone</s1><s2>Marseille</s2><s3>FRA</s3><sZ>1 aut.</sZ><sZ>4 aut.</sZ><sZ>6 aut.</sZ><sZ>8 aut.</sZ></inist:fA14><country>France</country><placeName><region type="region">Provence-Alpes-Côte d'Azur</region><region type="old region">Provence-Alpes-Côte d'Azur</region><settlement type="city">Marseille</settlement></placeName></affiliation></author><author><name sortKey="Regis, Jean" sort="Regis, Jean" uniqKey="Regis J" first="Jean" last="Regis">Jean Regis</name><affiliation wicri:level="3"><inist:fA14 i1="04"><s1>Department of Functional and Stereotactic Neurosurgery, University Hospital Timone</s1><s2>Marseille</s2><s3>FRA</s3><sZ>5 aut.</sZ><sZ>7 aut.</sZ></inist:fA14><country>France</country><placeName><region type="region">Provence-Alpes-Côte d'Azur</region><region type="old region">Provence-Alpes-Côte d'Azur</region><settlement type="city">Marseille</settlement></placeName></affiliation></author><author><name sortKey="Cherif, Andre Ali" sort="Cherif, Andre Ali" uniqKey="Cherif A" first="André Ali" last="Cherif">André Ali Cherif</name><affiliation wicri:level="3"><inist:fA14 i1="01"><s1>Department of Neurology, University Hospital Timone</s1><s2>Marseille</s2><s3>FRA</s3><sZ>1 aut.</sZ><sZ>4 aut.</sZ><sZ>6 aut.</sZ><sZ>8 aut.</sZ></inist:fA14><country>France</country><placeName><region type="region">Provence-Alpes-Côte d'Azur</region><region type="old region">Provence-Alpes-Côte d'Azur</region><settlement type="city">Marseille</settlement></placeName></affiliation></author><author><name sortKey="Peragut, Jean Claude" sort="Peragut, Jean Claude" uniqKey="Peragut J" first="Jean Claude" last="Peragut">Jean Claude Peragut</name><affiliation wicri:level="3"><inist:fA14 i1="04"><s1>Department of Functional and Stereotactic Neurosurgery, University Hospital Timone</s1><s2>Marseille</s2><s3>FRA</s3><sZ>5 aut.</sZ><sZ>7 aut.</sZ></inist:fA14><country>France</country><placeName><region type="region">Provence-Alpes-Côte d'Azur</region><region type="old region">Provence-Alpes-Côte d'Azur</region><settlement type="city">Marseille</settlement></placeName></affiliation></author><author><name sortKey="Azulay, Jean Philippe" sort="Azulay, Jean Philippe" uniqKey="Azulay J" first="Jean Philippe" last="Azulay">Jean Philippe Azulay</name><affiliation wicri:level="3"><inist:fA14 i1="01"><s1>Department of Neurology, University Hospital Timone</s1><s2>Marseille</s2><s3>FRA</s3><sZ>1 aut.</sZ><sZ>4 aut.</sZ><sZ>6 aut.</sZ><sZ>8 aut.</sZ></inist:fA14><country>France</country><placeName><region type="region">Provence-Alpes-Côte d'Azur</region><region type="old region">Provence-Alpes-Côte d'Azur</region><settlement type="city">Marseille</settlement></placeName></affiliation></author></titleStmt><publicationStmt><idno type="wicri:source">INIST</idno><idno type="inist">05-0444034</idno><date when="2005">2005</date><idno type="stanalyst">PASCAL 05-0444034 INIST</idno><idno type="RBID">Pascal:05-0444034</idno><idno type="wicri:Area/PascalFrancis/Corpus">000C42</idno><idno type="wicri:Area/PascalFrancis/Curation">000792</idno><idno type="wicri:Area/PascalFrancis/Checkpoint">000B56</idno><idno type="wicri:explorRef" wicri:stream="PascalFrancis" wicri:step="Checkpoint">000B56</idno><idno type="wicri:doubleKey">0885-3185:2005:Witjas T:addiction:in:parkinson</idno><idno type="wicri:Area/Main/Merge">003179</idno></publicationStmt><sourceDesc><biblStruct><analytic><title xml:lang="en" level="a">Addiction in Parkinson's disease : Impact of subthalamic nucleus deep brain stimulation</title><author><name sortKey="Witjas, Tatiana" sort="Witjas, Tatiana" uniqKey="Witjas T" first="Tatiana" last="Witjas">Tatiana Witjas</name><affiliation wicri:level="3"><inist:fA14 i1="01"><s1>Department of Neurology, University Hospital Timone</s1><s2>Marseille</s2><s3>FRA</s3><sZ>1 aut.</sZ><sZ>4 aut.</sZ><sZ>6 aut.</sZ><sZ>8 aut.</sZ></inist:fA14><country>France</country><placeName><region type="region">Provence-Alpes-Côte d'Azur</region><region type="old region">Provence-Alpes-Côte d'Azur</region><settlement type="city">Marseille</settlement></placeName></affiliation></author><author><name sortKey="Baunez, Christelle" sort="Baunez, Christelle" uniqKey="Baunez C" first="Christelle" last="Baunez">Christelle Baunez</name><affiliation wicri:level="3"><inist:fA14 i1="02"><s1>Laboratory of Neurobiology of Cognition, CNRS</s1><s2>Marseille</s2><s3>FRA</s3><sZ>2 aut.</sZ></inist:fA14><country>France</country><placeName><region type="region">Provence-Alpes-Côte d'Azur</region><region type="old region">Provence-Alpes-Côte d'Azur</region><settlement type="city">Marseille</settlement></placeName></affiliation></author><author><name sortKey="Henry, Jean Marc" sort="Henry, Jean Marc" uniqKey="Henry J" first="Jean Marc" last="Henry">Jean Marc Henry</name><affiliation wicri:level="3"><inist:fA14 i1="03"><s1>Department of Psychiatry, University Hospital Timone</s1><s2>Marseille</s2><s3>FRA</s3><sZ>3 aut.</sZ></inist:fA14><country>France</country><placeName><region type="region">Provence-Alpes-Côte d'Azur</region><region type="old region">Provence-Alpes-Côte d'Azur</region><settlement type="city">Marseille</settlement></placeName></affiliation></author><author><name sortKey="Delfini, Marie" sort="Delfini, Marie" uniqKey="Delfini M" first="Marie" last="Delfini">Marie Delfini</name><affiliation wicri:level="3"><inist:fA14 i1="01"><s1>Department of Neurology, University Hospital Timone</s1><s2>Marseille</s2><s3>FRA</s3><sZ>1 aut.</sZ><sZ>4 aut.</sZ><sZ>6 aut.</sZ><sZ>8 aut.</sZ></inist:fA14><country>France</country><placeName><region type="region">Provence-Alpes-Côte d'Azur</region><region type="old region">Provence-Alpes-Côte d'Azur</region><settlement type="city">Marseille</settlement></placeName></affiliation></author><author><name sortKey="Regis, Jean" sort="Regis, Jean" uniqKey="Regis J" first="Jean" last="Regis">Jean Regis</name><affiliation wicri:level="3"><inist:fA14 i1="04"><s1>Department of Functional and Stereotactic Neurosurgery, University Hospital Timone</s1><s2>Marseille</s2><s3>FRA</s3><sZ>5 aut.</sZ><sZ>7 aut.</sZ></inist:fA14><country>France</country><placeName><region type="region">Provence-Alpes-Côte d'Azur</region><region type="old region">Provence-Alpes-Côte d'Azur</region><settlement type="city">Marseille</settlement></placeName></affiliation></author><author><name sortKey="Cherif, Andre Ali" sort="Cherif, Andre Ali" uniqKey="Cherif A" first="André Ali" last="Cherif">André Ali Cherif</name><affiliation wicri:level="3"><inist:fA14 i1="01"><s1>Department of Neurology, University Hospital Timone</s1><s2>Marseille</s2><s3>FRA</s3><sZ>1 aut.</sZ><sZ>4 aut.</sZ><sZ>6 aut.</sZ><sZ>8 aut.</sZ></inist:fA14><country>France</country><placeName><region type="region">Provence-Alpes-Côte d'Azur</region><region type="old region">Provence-Alpes-Côte d'Azur</region><settlement type="city">Marseille</settlement></placeName></affiliation></author><author><name sortKey="Peragut, Jean Claude" sort="Peragut, Jean Claude" uniqKey="Peragut J" first="Jean Claude" last="Peragut">Jean Claude Peragut</name><affiliation wicri:level="3"><inist:fA14 i1="04"><s1>Department of Functional and Stereotactic Neurosurgery, University Hospital Timone</s1><s2>Marseille</s2><s3>FRA</s3><sZ>5 aut.</sZ><sZ>7 aut.</sZ></inist:fA14><country>France</country><placeName><region type="region">Provence-Alpes-Côte d'Azur</region><region type="old region">Provence-Alpes-Côte d'Azur</region><settlement type="city">Marseille</settlement></placeName></affiliation></author><author><name sortKey="Azulay, Jean Philippe" sort="Azulay, Jean Philippe" uniqKey="Azulay J" first="Jean Philippe" last="Azulay">Jean Philippe Azulay</name><affiliation wicri:level="3"><inist:fA14 i1="01"><s1>Department of Neurology, University Hospital Timone</s1><s2>Marseille</s2><s3>FRA</s3><sZ>1 aut.</sZ><sZ>4 aut.</sZ><sZ>6 aut.</sZ><sZ>8 aut.</sZ></inist:fA14><country>France</country><placeName><region type="region">Provence-Alpes-Côte d'Azur</region><region type="old region">Provence-Alpes-Côte d'Azur</region><settlement type="city">Marseille</settlement></placeName></affiliation></author></analytic><series><title level="j" type="main">Movement disorders</title><title level="j" type="abbreviated">Mov. disord.</title><idno type="ISSN">0885-3185</idno><imprint><date when="2005">2005</date></imprint></series></biblStruct></sourceDesc><seriesStmt><title level="j" type="main">Movement disorders</title><title level="j" type="abbreviated">Mov. disord.</title><idno type="ISSN">0885-3185</idno></seriesStmt></fileDesc><profileDesc><textClass><keywords scheme="KwdEn" xml:lang="en"><term>Addiction</term><term>Deep brain stimulation</term><term>Dopamine</term><term>Drug of abuse</term><term>Dyskinesia</term><term>Nervous system diseases</term><term>Parkinson disease</term><term>Subthalamic nucleus</term></keywords><keywords scheme="Pascal" xml:lang="fr"><term>Système nerveux pathologie</term><term>Addiction</term><term>Parkinson maladie</term><term>Dyskinésie</term><term>Substance toxicomanogène</term><term>Noyau sousthalamique</term><term>Dopamine</term><term>Stimulation cérébrale profonde</term></keywords></textClass></profileDesc></teiHeader><front><div type="abstract" xml:lang="en">In Parkinson's disease, dopamine dysregulation syndrome (DDS) is characterized by severe dopamine addiction and behavioral disorders such as manic psychosis, hypersexuality, pathological gambling, and mood swings. Here, we describe the case of 2 young parkinsonian patients suffering from disabling motor fluctuations and dyskinesia associated with severe DDS. In addition to alleviating the motor disability in both patients, subthalamic nucleus (STN) deep brain stimulation greatly reduced the behavioral disorders as well as completely abolished the addiction to dopaminergic treatment. Dopaminergic addiction in patients with Parkinson's disease, therefore, does not constitute an obstacle to high-frequency STN stimulation, and this treatment may even cure the addiction.</div></front></TEI></INIST><PubMed><TEI><teiHeader><fileDesc><titleStmt><title xml:lang="en">Addiction in Parkinson's disease: impact of subthalamic nucleus deep brain stimulation.</title><author><name sortKey="Witjas, Tatiana" sort="Witjas, Tatiana" uniqKey="Witjas T" first="Tatiana" last="Witjas">Tatiana Witjas</name><affiliation wicri:level="3"><nlm:affiliation>Department of Neurology, University Hospital Timone, Marseille, France. twitjas@yahoo.com</nlm:affiliation><country xml:lang="fr">France</country><wicri:regionArea>Department of Neurology, University Hospital Timone, Marseille</wicri:regionArea><placeName><region type="region">Provence-Alpes-Côte d'Azur</region><region type="old region">Provence-Alpes-Côte d'Azur</region><settlement type="city">Marseille</settlement></placeName></affiliation></author><author><name sortKey="Baunez, Christelle" sort="Baunez, Christelle" uniqKey="Baunez C" first="Christelle" last="Baunez">Christelle Baunez</name></author><author><name sortKey="Henry, Jean Marc" sort="Henry, Jean Marc" uniqKey="Henry J" first="Jean Marc" last="Henry">Jean Marc Henry</name></author><author><name sortKey="Delfini, Marie" sort="Delfini, Marie" uniqKey="Delfini M" first="Marie" last="Delfini">Marie Delfini</name></author><author><name sortKey="Regis, Jean" sort="Regis, Jean" uniqKey="Regis J" first="Jean" last="Regis">Jean Regis</name></author><author><name sortKey="Cherif, Andre Ali" sort="Cherif, Andre Ali" uniqKey="Cherif A" first="André Ali" last="Cherif">André Ali Cherif</name></author><author><name sortKey="Peragut, Jean Claude" sort="Peragut, Jean Claude" uniqKey="Peragut J" first="Jean Claude" last="Peragut">Jean Claude Peragut</name></author><author><name sortKey="Azulay, Jean Philippe" sort="Azulay, Jean Philippe" uniqKey="Azulay J" first="Jean Philippe" last="Azulay">Jean Philippe Azulay</name></author></titleStmt><publicationStmt><idno type="wicri:source">PubMed</idno><date when="2005">2005</date><idno type="RBID">pubmed:15858803</idno><idno type="pmid">15858803</idno><idno type="doi">10.1002/mds.20501</idno><idno type="wicri:Area/PubMed/Corpus">000F35</idno><idno type="wicri:explorRef" wicri:stream="PubMed" wicri:step="Corpus" wicri:corpus="PubMed">000F35</idno><idno type="wicri:Area/PubMed/Curation">000E95</idno><idno type="wicri:explorRef" wicri:stream="PubMed" wicri:step="Curation">000E95</idno><idno type="wicri:Area/PubMed/Checkpoint">000E95</idno><idno type="wicri:explorRef" wicri:stream="Checkpoint" wicri:step="PubMed">000E95</idno><idno type="wicri:Area/Ncbi/Merge">000515</idno><idno type="wicri:Area/Ncbi/Curation">000515</idno><idno type="wicri:Area/Ncbi/Checkpoint">000515</idno><idno type="wicri:doubleKey">0885-3185:2005:Witjas T:addiction:in:parkinson</idno><idno type="wicri:Area/Main/Merge">002F59</idno></publicationStmt><sourceDesc><biblStruct><analytic><title xml:lang="en">Addiction in Parkinson's disease: impact of subthalamic nucleus deep brain stimulation.</title><author><name sortKey="Witjas, Tatiana" sort="Witjas, Tatiana" uniqKey="Witjas T" first="Tatiana" last="Witjas">Tatiana Witjas</name><affiliation wicri:level="3"><nlm:affiliation>Department of Neurology, University Hospital Timone, Marseille, France. twitjas@yahoo.com</nlm:affiliation><country xml:lang="fr">France</country><wicri:regionArea>Department of Neurology, University Hospital Timone, Marseille</wicri:regionArea><placeName><region type="region">Provence-Alpes-Côte d'Azur</region><region type="old region">Provence-Alpes-Côte d'Azur</region><settlement type="city">Marseille</settlement></placeName></affiliation></author><author><name sortKey="Baunez, Christelle" sort="Baunez, Christelle" uniqKey="Baunez C" first="Christelle" last="Baunez">Christelle Baunez</name></author><author><name sortKey="Henry, Jean Marc" sort="Henry, Jean Marc" uniqKey="Henry J" first="Jean Marc" last="Henry">Jean Marc Henry</name></author><author><name sortKey="Delfini, Marie" sort="Delfini, Marie" uniqKey="Delfini M" first="Marie" last="Delfini">Marie Delfini</name></author><author><name sortKey="Regis, Jean" sort="Regis, Jean" uniqKey="Regis J" first="Jean" last="Regis">Jean Regis</name></author><author><name sortKey="Cherif, Andre Ali" sort="Cherif, Andre Ali" uniqKey="Cherif A" first="André Ali" last="Cherif">André Ali Cherif</name></author><author><name sortKey="Peragut, Jean Claude" sort="Peragut, Jean Claude" uniqKey="Peragut J" first="Jean Claude" last="Peragut">Jean Claude Peragut</name></author><author><name sortKey="Azulay, Jean Philippe" sort="Azulay, Jean Philippe" uniqKey="Azulay J" first="Jean Philippe" last="Azulay">Jean Philippe Azulay</name></author></analytic><series><title level="j">Movement disorders : official journal of the Movement Disorder Society</title><idno type="ISSN">0885-3185</idno><imprint><date when="2005" type="published">2005</date></imprint></series></biblStruct></sourceDesc></fileDesc><profileDesc><textClass><keywords scheme="KwdEn" xml:lang="en"><term>Adult</term><term>Behavior, Addictive (complications)</term><term>Behavior, Addictive (therapy)</term><term>Clinical Protocols</term><term>Deep Brain Stimulation (methods)</term><term>Humans</term><term>Male</term><term>Middle Aged</term><term>Parkinson Disease (complications)</term><term>Parkinson Disease (therapy)</term><term>Subthalamic Nucleus (radiation effects)</term></keywords><keywords scheme="MESH" qualifier="complications" xml:lang="en"><term>Behavior, Addictive</term><term>Parkinson Disease</term></keywords><keywords scheme="MESH" qualifier="methods" xml:lang="en"><term>Deep Brain Stimulation</term></keywords><keywords scheme="MESH" qualifier="radiation effects" xml:lang="en"><term>Subthalamic Nucleus</term></keywords><keywords scheme="MESH" qualifier="therapy" xml:lang="en"><term>Behavior, Addictive</term><term>Parkinson Disease</term></keywords><keywords scheme="MESH" xml:lang="en"><term>Adult</term><term>Clinical Protocols</term><term>Humans</term><term>Male</term><term>Middle Aged</term></keywords></textClass></profileDesc></teiHeader><front><div type="abstract" xml:lang="en">In Parkinson's disease, dopamine dysregulation syndrome (DDS) is characterized by severe dopamine addiction and behavioral disorders such as manic psychosis, hypersexuality, pathological gambling, and mood swings. Here, we describe the case of 2 young parkinsonian patients suffering from disabling motor fluctuations and dyskinesia associated with severe DDS. In addition to alleviating the motor disability in both patients, subthalamic nucleus (STN) deep brain stimulation greatly reduced the behavioral disorders as well as completely abolished the addiction to dopaminergic treatment. Dopaminergic addiction in patients with Parkinson's disease, therefore, does not constitute an obstacle to high-frequency STN stimulation, and this treatment may even cure the addiction.</div></front></TEI></PubMed></double></record>Pour manipuler ce document sous Unix (Dilib)
EXPLOR_STEP=$WICRI_ROOT/Wicri/Sante/explor/ParkinsonFranceV1/Data/Main/Curation
HfdSelect -h $EXPLOR_STEP/biblio.hfd -nk 002D96 | SxmlIndent | more
Ou
HfdSelect -h $EXPLOR_AREA/Data/Main/Curation/biblio.hfd -nk 002D96 | SxmlIndent | more
Pour mettre un lien sur cette page dans le réseau Wicri
{{Explor lien
|wiki= Wicri/Sante
|area= ParkinsonFranceV1
|flux= Main
|étape= Curation
|type= RBID
|clé= Pascal:05-0444034
|texte= Addiction in Parkinson's disease : Impact of subthalamic nucleus deep brain stimulation
}}
| This area was generated with Dilib version V0.6.29. |  |