ParkinsonFranceV1, PubMed, Corpus, bibRecord, 000F35

Addiction in Parkinson's disease: impact of subthalamic nucleus deep brain stimulation.

Identifieur interne : 000F35 ( PubMed/Corpus ); précédent : 000F34; suivant : 000F36

Addiction in Parkinson's disease: impact of subthalamic nucleus deep brain stimulation.

Auteurs : Tatiana Witjas ; Christelle Baunez ; Jean Marc Henry ; Marie Delfini ; Jean Regis ; André Ali Cherif ; Jean Claude Peragut ; Jean Philippe Azulay

Source :

Movement disorders : official journal of the Movement Disorder Society [ 0885-3185 ] ; 2005.

RBID : pubmed:15858803

English descriptors

KwdEn :
- Adult, Behavior, Addictive (complications), Behavior, Addictive (therapy), Clinical Protocols, Deep Brain Stimulation (methods), Humans, Male, Middle Aged, Parkinson Disease (complications), Parkinson Disease (therapy), Subthalamic Nucleus (radiation effects).
MESH :
- complications : Behavior, Addictive, Parkinson Disease.
- methods : Deep Brain Stimulation.
- radiation effects : Subthalamic Nucleus.
- therapy : Behavior, Addictive, Parkinson Disease.
- Adult, Clinical Protocols, Humans, Male, Middle Aged.

Abstract

In Parkinson's disease, dopamine dysregulation syndrome (DDS) is characterized by severe dopamine addiction and behavioral disorders such as manic psychosis, hypersexuality, pathological gambling, and mood swings. Here, we describe the case of 2 young parkinsonian patients suffering from disabling motor fluctuations and dyskinesia associated with severe DDS. In addition to alleviating the motor disability in both patients, subthalamic nucleus (STN) deep brain stimulation greatly reduced the behavioral disorders as well as completely abolished the addiction to dopaminergic treatment. Dopaminergic addiction in patients with Parkinson's disease, therefore, does not constitute an obstacle to high-frequency STN stimulation, and this treatment may even cure the addiction.

DOI: 10.1002/mds.20501
PubMed: 15858803

Links to Exploration step

pubmed:15858803

Le document en format XML

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<author><name sortKey="Witjas, Tatiana" sort="Witjas, Tatiana" uniqKey="Witjas T" first="Tatiana" last="Witjas">Tatiana Witjas</name>
<affiliation><nlm:affiliation>Department of Neurology, University Hospital Timone, Marseille, France. twitjas@yahoo.com</nlm:affiliation>
</affiliation>
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<author><name sortKey="Baunez, Christelle" sort="Baunez, Christelle" uniqKey="Baunez C" first="Christelle" last="Baunez">Christelle Baunez</name>
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<author><name sortKey="Henry, Jean Marc" sort="Henry, Jean Marc" uniqKey="Henry J" first="Jean Marc" last="Henry">Jean Marc Henry</name>
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<author><name sortKey="Delfini, Marie" sort="Delfini, Marie" uniqKey="Delfini M" first="Marie" last="Delfini">Marie Delfini</name>
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<author><name sortKey="Regis, Jean" sort="Regis, Jean" uniqKey="Regis J" first="Jean" last="Regis">Jean Regis</name>
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<author><name sortKey="Cherif, Andre Ali" sort="Cherif, Andre Ali" uniqKey="Cherif A" first="André Ali" last="Cherif">André Ali Cherif</name>
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<author><name sortKey="Peragut, Jean Claude" sort="Peragut, Jean Claude" uniqKey="Peragut J" first="Jean Claude" last="Peragut">Jean Claude Peragut</name>
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<author><name sortKey="Azulay, Jean Philippe" sort="Azulay, Jean Philippe" uniqKey="Azulay J" first="Jean Philippe" last="Azulay">Jean Philippe Azulay</name>
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<author><name sortKey="Delfini, Marie" sort="Delfini, Marie" uniqKey="Delfini M" first="Marie" last="Delfini">Marie Delfini</name>
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<term>Deep Brain Stimulation (methods)</term>
<term>Humans</term>
<term>Male</term>
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<term>Parkinson Disease (complications)</term>
<term>Parkinson Disease (therapy)</term>
<term>Subthalamic Nucleus (radiation effects)</term>
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<term>Parkinson Disease</term>
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<keywords scheme="MESH" xml:lang="en"><term>Adult</term>
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<front><div type="abstract" xml:lang="en">In Parkinson's disease, dopamine dysregulation syndrome (DDS) is characterized by severe dopamine addiction and behavioral disorders such as manic psychosis, hypersexuality, pathological gambling, and mood swings. Here, we describe the case of 2 young parkinsonian patients suffering from disabling motor fluctuations and dyskinesia associated with severe DDS. In addition to alleviating the motor disability in both patients, subthalamic nucleus (STN) deep brain stimulation greatly reduced the behavioral disorders as well as completely abolished the addiction to dopaminergic treatment. Dopaminergic addiction in patients with Parkinson's disease, therefore, does not constitute an obstacle to high-frequency STN stimulation, and this treatment may even cure the addiction.</div>
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<Title>Movement disorders : official journal of the Movement Disorder Society</Title>
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<ArticleTitle>Addiction in Parkinson's disease: impact of subthalamic nucleus deep brain stimulation.</ArticleTitle>
<Pagination><MedlinePgn>1052-5</MedlinePgn>
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<Abstract><AbstractText>In Parkinson's disease, dopamine dysregulation syndrome (DDS) is characterized by severe dopamine addiction and behavioral disorders such as manic psychosis, hypersexuality, pathological gambling, and mood swings. Here, we describe the case of 2 young parkinsonian patients suffering from disabling motor fluctuations and dyskinesia associated with severe DDS. In addition to alleviating the motor disability in both patients, subthalamic nucleus (STN) deep brain stimulation greatly reduced the behavioral disorders as well as completely abolished the addiction to dopaminergic treatment. Dopaminergic addiction in patients with Parkinson's disease, therefore, does not constitute an obstacle to high-frequency STN stimulation, and this treatment may even cure the addiction.</AbstractText>
<CopyrightInformation>Copyright 2005 Movement Disorder Society</CopyrightInformation>
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<QualifierName UI="Q000150" MajorTopicYN="N">complications</QualifierName>
<QualifierName UI="Q000628" MajorTopicYN="Y">therapy</QualifierName>
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<MeshHeading><DescriptorName UI="D020531" MajorTopicYN="N">Subthalamic Nucleus</DescriptorName>
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La maladie de Parkinson en France (serveur d'exploration)

Addiction in Parkinson's disease: impact of subthalamic nucleus deep brain stimulation.

Addiction in Parkinson's disease: impact of subthalamic nucleus deep brain stimulation.

Source :

English descriptors

Abstract

Links to Exploration step

Le document en format XML

Pour manipuler ce document sous Unix (Dilib)

Pour mettre un lien sur cette page dans le réseau Wicri

Pour générer des pages wiki