PANDEMIC INFLUENZA A (H1N1) 2009 PRESENTING AS A MILD DISEASE IN CHILDREN IN A CROATIAN CLINICAL CENTRE
Identifieur interne : 000901 ( Pmc/Curation ); précédent : 000900; suivant : 000902PANDEMIC INFLUENZA A (H1N1) 2009 PRESENTING AS A MILD DISEASE IN CHILDREN IN A CROATIAN CLINICAL CENTRE
Auteurs : Svjetlana Grgi ; Elvira Eljuska-Tošev ; Jadranka Nikoli ; Filipa Markoti ; Mladenka Vukojevi ; Helien Bebek-Ivankovi ; Ilija KuzmanSource :
- Acta Clinica Croatica [ 0353-9466 ] ; 2019.
Abstract
Pandemic influenza A virus (H1N1) 2009 causes a disease that is epidemiologically and clinically not significantly different from seasonal influenza, but there are differences. The aim of the study was to display and compare epidemiological and clinical characteristics of pandemic influenza in children. At Dr. Fran Mihaljević University Hospital for Infectious Diseases in Zagreb, in the first two seasons, the incidence of pandemic influenza virus A (H1N1) in particular was exhaustively analyzed only in patients with laboratory-confirmed pandemic influenza A virus (H1N1) 2009. In hospitalized children with documented influenza pandemic, moderate form of the disease predominated, which ultimately meant shorter hospital stay and fewer complications. Otitis media was the rarest complication in children in both seasons. In conclusion, children younger than 5 years, especially boys, were vulnerable groups for pandemic influenza, presenting as a mild disease with low mortality and few complications. Most of the affected children with influenza did not have important risk factors such as asthma and obesity, highlighted by other authors as significant risk factors.
Url:
DOI: 10.20471/acc.2019.58.03.04
PubMed: 31969753
PubMed Central: 6971810
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<record><TEI><teiHeader><fileDesc><titleStmt><title xml:lang="en">PANDEMIC INFLUENZA A (H1N1) 2009 PRESENTING AS A MILD DISEASE IN CHILDREN IN A CROATIAN CLINICAL CENTRE</title><author><name sortKey="Grgi, Svjetlana" sort="Grgi, Svjetlana" uniqKey="Grgi S" first="Svjetlana" last="Grgi">Svjetlana Grgi</name></author><author><name sortKey=" Eljuska Tosev, Elvira" sort=" Eljuska Tosev, Elvira" uniqKey=" Eljuska Tosev E" first="Elvira" last=" Eljuska-Tošev">Elvira Eljuska-Tošev</name></author><author><name sortKey="Nikoli, Jadranka" sort="Nikoli, Jadranka" uniqKey="Nikoli J" first="Jadranka" last="Nikoli">Jadranka Nikoli</name></author><author><name sortKey="Markoti, Filipa" sort="Markoti, Filipa" uniqKey="Markoti F" first="Filipa" last="Markoti">Filipa Markoti</name></author><author><name sortKey="Vukojevi, Mladenka" sort="Vukojevi, Mladenka" uniqKey="Vukojevi M" first="Mladenka" last="Vukojevi">Mladenka Vukojevi</name></author><author><name sortKey="Bebek Ivankovi, Helien" sort="Bebek Ivankovi, Helien" uniqKey="Bebek Ivankovi H" first="Helien" last="Bebek-Ivankovi">Helien Bebek-Ivankovi</name></author><author><name sortKey="Kuzman, Ilija" sort="Kuzman, Ilija" uniqKey="Kuzman I" first="Ilija" last="Kuzman">Ilija Kuzman</name></author></titleStmt><publicationStmt><idno type="wicri:source">PMC</idno><idno type="pmid">31969753</idno><idno type="pmc">6971810</idno><idno type="url">http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6971810</idno><idno type="RBID">PMC:6971810</idno><idno type="doi">10.20471/acc.2019.58.03.04</idno><date when="2019">2019</date><idno type="wicri:Area/Pmc/Corpus">000901</idno><idno type="wicri:explorRef" wicri:stream="Pmc" wicri:step="Corpus" wicri:corpus="PMC">000901</idno><idno type="wicri:Area/Pmc/Curation">000901</idno><idno type="wicri:explorRef" wicri:stream="Pmc" wicri:step="Curation">000901</idno></publicationStmt><sourceDesc><biblStruct><analytic><title xml:lang="en" level="a" type="main">PANDEMIC INFLUENZA A (H1N1) 2009 PRESENTING AS A MILD DISEASE IN CHILDREN IN A CROATIAN CLINICAL CENTRE</title><author><name sortKey="Grgi, Svjetlana" sort="Grgi, Svjetlana" uniqKey="Grgi S" first="Svjetlana" last="Grgi">Svjetlana Grgi</name></author><author><name sortKey=" Eljuska Tosev, Elvira" sort=" Eljuska Tosev, Elvira" uniqKey=" Eljuska Tosev E" first="Elvira" last=" Eljuska-Tošev">Elvira Eljuska-Tošev</name></author><author><name sortKey="Nikoli, Jadranka" sort="Nikoli, Jadranka" uniqKey="Nikoli J" first="Jadranka" last="Nikoli">Jadranka Nikoli</name></author><author><name sortKey="Markoti, Filipa" sort="Markoti, Filipa" uniqKey="Markoti F" first="Filipa" last="Markoti">Filipa Markoti</name></author><author><name sortKey="Vukojevi, Mladenka" sort="Vukojevi, Mladenka" uniqKey="Vukojevi M" first="Mladenka" last="Vukojevi">Mladenka Vukojevi</name></author><author><name sortKey="Bebek Ivankovi, Helien" sort="Bebek Ivankovi, Helien" uniqKey="Bebek Ivankovi H" first="Helien" last="Bebek-Ivankovi">Helien Bebek-Ivankovi</name></author><author><name sortKey="Kuzman, Ilija" sort="Kuzman, Ilija" uniqKey="Kuzman I" first="Ilija" last="Kuzman">Ilija Kuzman</name></author></analytic><series><title level="j">Acta Clinica Croatica</title><idno type="ISSN">0353-9466</idno><idno type="eISSN">1333-9451</idno><imprint><date when="2019">2019</date></imprint></series></biblStruct></sourceDesc></fileDesc><profileDesc><textClass></textClass></profileDesc></teiHeader><front><div type="abstract" xml:lang="en"><title>SUMMARY</title><p>Pandemic influenza A virus (H1N1) 2009 causes a disease that is epidemiologically and clinically not significantly different from seasonal influenza, but there are differences. The aim of the study was to display and compare epidemiological and clinical characteristics of pandemic influenza in children. At Dr. Fran Mihaljević University Hospital for Infectious Diseases in Zagreb, in the first two seasons, the incidence of pandemic influenza virus A (H1N1) in particular was exhaustively analyzed only in patients with laboratory-confirmed pandemic influenza A virus (H1N1) 2009. In hospitalized children with documented influenza pandemic, moderate form of the disease predominated, which ultimately meant shorter hospital stay and fewer complications. Otitis media was the rarest complication in children in both seasons. In conclusion, children younger than 5 years, especially boys, were vulnerable groups for pandemic influenza, presenting as a mild disease with low mortality and few complications. Most of the affected children with influenza did not have important risk factors such as asthma and obesity, highlighted by other authors as significant risk factors.</p></div></front><back><div1 type="bibliography"><listBibl><biblStruct></biblStruct><biblStruct><analytic><author><name sortKey="Dolin, R" uniqKey="Dolin R">R Dolin</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Nicholson, Kg" uniqKey="Nicholson K">KG Nicholson</name></author></analytic></biblStruct><biblStruct></biblStruct><biblStruct><analytic><author><name sortKey="Peiris, Js" uniqKey="Peiris J">JS Peiris</name></author><author><name sortKey="Poon, Ll" uniqKey="Poon L">LL Poon</name></author><author><name sortKey="Guan, Y" uniqKey="Guan Y">Y Guan</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Mclean, E" uniqKey="Mclean E">E McLean</name></author><author><name sortKey="Pebody, Rg" uniqKey="Pebody R">RG Pebody</name></author><author><name 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G">G Tešović</name></author><author><name sortKey="Stemberger, L" uniqKey="Stemberger L">L Stemberger</name></author></analytic></biblStruct></listBibl></div1></back></TEI><pmc article-type="research-article"><pmc-dir>properties open_access</pmc-dir>
<front><journal-meta><journal-id journal-id-type="nlm-ta">Acta Clin Croat</journal-id><journal-id journal-id-type="iso-abbrev">Acta Clin Croat</journal-id><journal-id journal-id-type="publisher-id">ACC</journal-id><journal-title-group><journal-title>Acta Clinica Croatica</journal-title></journal-title-group><issn pub-type="ppub">0353-9466</issn><issn pub-type="epub">1333-9451</issn><publisher><publisher-name>Sestre Milosrdnice University Hospital and Institute of Clinical Medical Research, Vinogradska cesta c. 29 Zagreb</publisher-name></publisher></journal-meta><article-meta><article-id pub-id-type="pmid">31969753</article-id><article-id pub-id-type="pmc">6971810</article-id><article-id pub-id-type="publisher-id">acc-58-421</article-id><article-id pub-id-type="doi">10.20471/acc.2019.58.03.04</article-id><article-categories><subj-group subj-group-type="heading"><subject>Original Scientific Papers</subject></subj-group></article-categories><title-group><article-title>PANDEMIC INFLUENZA A (H1N1) 2009 PRESENTING AS A MILD DISEASE IN CHILDREN IN A CROATIAN CLINICAL CENTRE</article-title></title-group><contrib-group><contrib contrib-type="author" corresp="yes"><name><surname>Grgić</surname><given-names>Svjetlana</given-names></name><xref ref-type="aff" rid="aff1"><sup>1</sup></xref><xref ref-type="aff" rid="aff2"><sup>2</sup></xref></contrib><contrib contrib-type="author"><name><surname>Čeljuska-Tošev</surname><given-names>Elvira</given-names></name><xref ref-type="aff" rid="aff3"><sup>3</sup></xref></contrib><contrib contrib-type="author"><name><surname>Nikolić</surname><given-names>Jadranka</given-names></name><xref ref-type="aff" rid="aff1"><sup>1</sup></xref><xref ref-type="aff" rid="aff2"><sup>2</sup></xref></contrib><contrib contrib-type="author"><name><surname>Markotić</surname><given-names>Filipa</given-names></name><xref ref-type="aff" rid="aff2"><sup>2</sup></xref></contrib><contrib contrib-type="author"><name><surname>Vukojević</surname><given-names>Mladenka</given-names></name><xref ref-type="aff" rid="aff2"><sup>2</sup></xref></contrib><contrib contrib-type="author"><name><surname>Bebek-Ivanković</surname><given-names>Helien</given-names></name><xref ref-type="aff" rid="aff2"><sup>2</sup></xref></contrib><contrib contrib-type="author"><name><surname>Kuzman</surname><given-names>Ilija</given-names></name><xref ref-type="aff" rid="aff2"><sup>2</sup></xref><xref ref-type="aff" rid="aff3"><sup>3</sup></xref></contrib><aff><target id="aff1" target-type="aff"><sup>1</sup></target>Department of Infectious Diseases, Mostar University Hospital, Mostar, Bosnia and Herzegovina;<target id="aff2" target-type="aff"><sup>2</sup></target>School of Medicine, University of Mostar, Mostar, Bosnia and Herzegovina;<target id="aff3" target-type="aff"><sup>3</sup></target>School of Medicine, University of Zagreb,<institution>Dr. Fran Mihaljević University Hospital for Infectious Diseases</institution>,<addr-line>Zagreb</addr-line>,<country>Croatia</country></aff></contrib-group><author-notes><corresp id="cor1">Correspondence to: <italic>Svjetlana Grgić, MD, PhD</italic>, Department of Infectious Diseases, Mostar University Hospital, Kralja Tvrtka bb, 88000 Mostar, Bosnia and Herzegovina, E-mail: <email xlink:href="svjetlanag@gmail.com">svjetlanag@gmail.com</email></corresp></author-notes><pub-date pub-type="epub-ppub"><month>9</month><year>2019</year></pub-date><pmc-comment>Fake ppub date generated by PMC from publisher
pub-date/@pub-type='epub-ppub' </pmc-comment>
<pub-date pub-type="ppub"><month>9</month><year>2019</year></pub-date><volume>58</volume><issue>3</issue><fpage>421</fpage><lpage>429</lpage><history><date date-type="received"><day>15</day><month>3</month><year>2018</year></date><date date-type="accepted"><day>28</day><month>8</month><year>2018</year></date></history><permissions><copyright-year>2019</copyright-year><copyright-holder>Sestre Milosrdnice University Hospital</copyright-holder><license xlink:href="http://creativecommons.org/licenses/by-nc-nd/4.0/" specific-use="CC BY-NC-ND 4.0"><license-p>This is an open-access article distributed under the terms of the Creative Commons Attribution Non-Commercial No Derivatives (CC BY-NC-ND) 4.0 License.</license-p></license></permissions><abstract><title>SUMMARY</title><p>Pandemic influenza A virus (H1N1) 2009 causes a disease that is epidemiologically and clinically not significantly different from seasonal influenza, but there are differences. The aim of the study was to display and compare epidemiological and clinical characteristics of pandemic influenza in children. At Dr. Fran Mihaljević University Hospital for Infectious Diseases in Zagreb, in the first two seasons, the incidence of pandemic influenza virus A (H1N1) in particular was exhaustively analyzed only in patients with laboratory-confirmed pandemic influenza A virus (H1N1) 2009. In hospitalized children with documented influenza pandemic, moderate form of the disease predominated, which ultimately meant shorter hospital stay and fewer complications. Otitis media was the rarest complication in children in both seasons. In conclusion, children younger than 5 years, especially boys, were vulnerable groups for pandemic influenza, presenting as a mild disease with low mortality and few complications. Most of the affected children with influenza did not have important risk factors such as asthma and obesity, highlighted by other authors as significant risk factors.</p></abstract><kwd-group kwd-group-type="author"><title>Key words: </title><kwd>Influenza A virus</kwd><kwd>H1N1 subtype</kwd><kwd>Croatia</kwd><kwd>Risk factors</kwd><kwd>Child</kwd></kwd-group></article-meta></front></pmc></record>Pour manipuler ce document sous Unix (Dilib)
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