Generation of human neutralizing monoclonal antibodies against the 2009 pandemic H1N1 virus from peripheral blood memory B lymphocytes

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Generation of human neutralizing monoclonal antibodies against the 2009 pandemic H1N1 virus from peripheral blood memory B lymphocytes

Auteurs : Hao Wang ; Chi Ma ; Yanlai Lu ; Xu Ji ; Yongsheng Pang ; Fang Hua ; Lianxian Cui ; Denian Ba ; Wei He

Source :

• Cellular and Molecular Immunology [ 1672-7681 ] ; 2013.

RBID : PMC:4003197

Descripteurs français

• KwdFr :
  • Anticorps antiviraux (biosynthèse), Anticorps antiviraux (isolement et purification), Anticorps antiviraux (sang), Anticorps monoclonaux (biosynthèse), Anticorps monoclonaux (isolement et purification), Anticorps monoclonaux (sang), Anticorps neutralisants (biosynthèse), Anticorps neutralisants (isolement et purification), Anticorps neutralisants (sang), Chine (épidémiologie), Grippe humaine (), Grippe humaine (immunologie), Grippe humaine (sang), Grippe humaine (épidémiologie), Herpèsvirus humain de type 4 (génétique), Herpèsvirus humain de type 4 (immunologie), Humains, Lymphocytes B (immunologie), Lymphocytes B (métabolisme), Lymphocytes B (virologie), Mémoire immunologique, Pandémies, Sous-type H1N1 du virus de la grippe A (immunologie), Tests d'inhibition de l'hémagglutination, Tests de criblage à haut débit, Tests de neutralisation, Vaccination, Vaccins antigrippaux (administration et posologie).
• MESH :
  • administration et posologie : Vaccins antigrippaux.
  • biosynthèse : Anticorps antiviraux, Anticorps monoclonaux, Anticorps neutralisants.
  • génétique : Herpèsvirus humain de type 4.
  • immunologie : Grippe humaine, Herpèsvirus humain de type 4, Lymphocytes B, Sous-type H1N1 du virus de la grippe A.
  • isolement et purification : Anticorps antiviraux, Anticorps monoclonaux, Anticorps neutralisants.
  • métabolisme : Lymphocytes B.
  • sang : Anticorps antiviraux, Anticorps monoclonaux, Anticorps neutralisants, Grippe humaine.
  • virologie : Lymphocytes B.
  • épidémiologie : Chine, Grippe humaine.
  • Grippe humaine, Humains, Mémoire immunologique, Pandémies, Tests d'inhibition de l'hémagglutination, Tests de criblage à haut débit, Tests de neutralisation, Vaccination.
• Wicri :
  • geographic : République populaire de Chine.

English descriptors

• KwdEn :
  • Antibodies, Monoclonal (biosynthesis), Antibodies, Monoclonal (blood), Antibodies, Monoclonal (isolation & purification), Antibodies, Neutralizing (biosynthesis), Antibodies, Neutralizing (blood), Antibodies, Neutralizing (isolation & purification), Antibodies, Viral (biosynthesis), Antibodies, Viral (blood), Antibodies, Viral (isolation & purification), B-Lymphocytes (immunology), B-Lymphocytes (metabolism), B-Lymphocytes (virology), China (epidemiology), Hemagglutination Inhibition Tests, Herpesvirus 4, Human (genetics), Herpesvirus 4, Human (immunology), High-Throughput Screening Assays, Humans, Immunologic Memory, Influenza A Virus, H1N1 Subtype (immunology), Influenza Vaccines (administration & dosage), Influenza, Human (blood), Influenza, Human (epidemiology), Influenza, Human (immunology), Influenza, Human (prevention & control), Neutralization Tests, Pandemics, Vaccination.
• MESH :
  • chemical , administration & dosage : Influenza Vaccines.
  • chemical , biosynthesis : Antibodies, Monoclonal, Antibodies, Neutralizing, Antibodies, Viral.
  • chemical , blood : Antibodies, Monoclonal, Antibodies, Neutralizing, Antibodies, Viral.
  • chemical , isolation & purification : Antibodies, Monoclonal, Antibodies, Neutralizing, Antibodies, Viral.
  • geographic , epidemiology : China.
  • blood : Influenza, Human.
  • epidemiology : Influenza, Human.
  • genetics : Herpesvirus 4, Human.
  • immunology : B-Lymphocytes, Herpesvirus 4, Human, Influenza A Virus, H1N1 Subtype, Influenza, Human.
  • metabolism : B-Lymphocytes.
  • prevention & control : Influenza, Human.
  • virology : B-Lymphocytes.
  • Hemagglutination Inhibition Tests, High-Throughput Screening Assays, Humans, Immunologic Memory, Neutralization Tests, Pandemics, Vaccination.

Abstract

Url:

• http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4003197

DOI: 10.1038/cmi.2013.25
PubMed: 23912783
PubMed Central: 4003197

Affiliations:

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