Serveur d'exploration sur les pandémies grippales

Attention, ce site est en cours de développement !
Attention, site généré par des moyens informatiques à partir de corpus bruts.
Les informations ne sont donc pas validées.

Influenza A/pandemic 2009/H1N1 in the setting of allogeneic hematopoietic cell transplantation: a potentially catastrophic problem in a vulnerable population

Identifieur interne : 003919 ( Main/Exploration ); précédent : 003918; suivant : 003920

Influenza A/pandemic 2009/H1N1 in the setting of allogeneic hematopoietic cell transplantation: a potentially catastrophic problem in a vulnerable population

Auteurs : Mohamed A. Kharfan-Dabaja [États-Unis] ; Ana Velez [États-Unis] ; Karla Richards [États-Unis] ; John N. Greene [États-Unis] ; Teresa Field [États-Unis] ; Ramon Sandin [États-Unis]

Source :

RBID : Pascal:10-0161171

Descripteurs français

English descriptors

Abstract

We describe Influenza A/pandemic 2009/H1N1 in two allogeneic hematopoietic cell transplantation recipients. The main presentation in both cases consisted of flu-like symptoms manifesting as, fever, arthralgias and myalgias. The virus was isolated in one case from a throat swab and in another case following a bronchoalveolar lavage. Both patients received oseltamivir at a dose of 75 mg orally twice day. The dose of oseltamivir was increased to 150 mg twice per day due to the lack of improvement or progression of symptoms. In one case, clinical symptoms resolved without sequelae. In the second case, pulmonary symptomatology continued to deteriorate, despite aggressive polymicrobial treatment, requiring mechanical ventilation and ultimately the patient died from respiratory failure. These cases highlight the potentially serious effect of the ongoing Influenza A/pandemic 2009/ H1N1 pandemic in this very vulnerable population and the urgent need to establish emergency preparedness strategies by oncology and bone marrow transplantation staff to face this serious healthcare challenge.


Affiliations:


Links toward previous steps (curation, corpus...)


Le document en format XML

<record>
<TEI>
<teiHeader>
<fileDesc>
<titleStmt>
<title xml:lang="en" level="a">Influenza A/pandemic 2009/H1N1 in the setting of allogeneic hematopoietic cell transplantation: a potentially catastrophic problem in a vulnerable population</title>
<author>
<name sortKey="Kharfan Dabaja, Mohamed A" sort="Kharfan Dabaja, Mohamed A" uniqKey="Kharfan Dabaja M" first="Mohamed A." last="Kharfan-Dabaja">Mohamed A. Kharfan-Dabaja</name>
<affiliation wicri:level="2">
<inist:fA14 i1="01">
<s1>Department of Blood and Marrow Transplantation, H. Lee Moffitt Cancer Center and Research Institute, 12902 Magnolia Drive, FOB-3</s1>
<s2>Tampa, FL 33612</s2>
<s3>USA</s3>
<sZ>1 aut.</sZ>
<sZ>2 aut.</sZ>
<sZ>3 aut.</sZ>
<sZ>4 aut.</sZ>
<sZ>5 aut.</sZ>
<sZ>6 aut.</sZ>
</inist:fA14>
<country>États-Unis</country>
<placeName>
<region type="state">Floride</region>
</placeName>
</affiliation>
<affiliation wicri:level="4">
<inist:fA14 i1="02">
<s1>Department of Oncological Sciences, H. Lee Moffitt Cancer Center and Research Institute/University of South Florida</s1>
<s2>Tampa, FL</s2>
<s3>USA</s3>
<sZ>1 aut.</sZ>
<sZ>2 aut.</sZ>
<sZ>4 aut.</sZ>
<sZ>5 aut.</sZ>
<sZ>6 aut.</sZ>
</inist:fA14>
<country>États-Unis</country>
<placeName>
<region type="state">Floride</region>
<settlement type="city">Tampa</settlement>
</placeName>
<orgName type="university">Université de Floride du Sud</orgName>
</affiliation>
</author>
<author>
<name sortKey="Velez, Ana" sort="Velez, Ana" uniqKey="Velez A" first="Ana" last="Velez">Ana Velez</name>
<affiliation wicri:level="2">
<inist:fA14 i1="01">
<s1>Department of Blood and Marrow Transplantation, H. Lee Moffitt Cancer Center and Research Institute, 12902 Magnolia Drive, FOB-3</s1>
<s2>Tampa, FL 33612</s2>
<s3>USA</s3>
<sZ>1 aut.</sZ>
<sZ>2 aut.</sZ>
<sZ>3 aut.</sZ>
<sZ>4 aut.</sZ>
<sZ>5 aut.</sZ>
<sZ>6 aut.</sZ>
</inist:fA14>
<country>États-Unis</country>
<placeName>
<region type="state">Floride</region>
</placeName>
</affiliation>
<affiliation wicri:level="4">
<inist:fA14 i1="02">
<s1>Department of Oncological Sciences, H. Lee Moffitt Cancer Center and Research Institute/University of South Florida</s1>
<s2>Tampa, FL</s2>
<s3>USA</s3>
<sZ>1 aut.</sZ>
<sZ>2 aut.</sZ>
<sZ>4 aut.</sZ>
<sZ>5 aut.</sZ>
<sZ>6 aut.</sZ>
</inist:fA14>
<country>États-Unis</country>
<placeName>
<region type="state">Floride</region>
<settlement type="city">Tampa</settlement>
</placeName>
<orgName type="university">Université de Floride du Sud</orgName>
</affiliation>
<affiliation wicri:level="4">
<inist:fA14 i1="03">
<s1>Division of Infectious Diseases, H. Lee Moffitt Cancer Center and Research Institute/University of South Florida</s1>
<s2>Tampa, FL</s2>
<s3>USA</s3>
<sZ>2 aut.</sZ>
<sZ>4 aut.</sZ>
</inist:fA14>
<country>États-Unis</country>
<placeName>
<region type="state">Floride</region>
<settlement type="city">Tampa</settlement>
</placeName>
<orgName type="university">Université de Floride du Sud</orgName>
</affiliation>
</author>
<author>
<name sortKey="Richards, Karla" sort="Richards, Karla" uniqKey="Richards K" first="Karla" last="Richards">Karla Richards</name>
<affiliation wicri:level="2">
<inist:fA14 i1="01">
<s1>Department of Blood and Marrow Transplantation, H. Lee Moffitt Cancer Center and Research Institute, 12902 Magnolia Drive, FOB-3</s1>
<s2>Tampa, FL 33612</s2>
<s3>USA</s3>
<sZ>1 aut.</sZ>
<sZ>2 aut.</sZ>
<sZ>3 aut.</sZ>
<sZ>4 aut.</sZ>
<sZ>5 aut.</sZ>
<sZ>6 aut.</sZ>
</inist:fA14>
<country>États-Unis</country>
<placeName>
<region type="state">Floride</region>
</placeName>
</affiliation>
</author>
<author>
<name sortKey="Greene, John N" sort="Greene, John N" uniqKey="Greene J" first="John N." last="Greene">John N. Greene</name>
<affiliation wicri:level="2">
<inist:fA14 i1="01">
<s1>Department of Blood and Marrow Transplantation, H. Lee Moffitt Cancer Center and Research Institute, 12902 Magnolia Drive, FOB-3</s1>
<s2>Tampa, FL 33612</s2>
<s3>USA</s3>
<sZ>1 aut.</sZ>
<sZ>2 aut.</sZ>
<sZ>3 aut.</sZ>
<sZ>4 aut.</sZ>
<sZ>5 aut.</sZ>
<sZ>6 aut.</sZ>
</inist:fA14>
<country>États-Unis</country>
<placeName>
<region type="state">Floride</region>
</placeName>
</affiliation>
<affiliation wicri:level="4">
<inist:fA14 i1="02">
<s1>Department of Oncological Sciences, H. Lee Moffitt Cancer Center and Research Institute/University of South Florida</s1>
<s2>Tampa, FL</s2>
<s3>USA</s3>
<sZ>1 aut.</sZ>
<sZ>2 aut.</sZ>
<sZ>4 aut.</sZ>
<sZ>5 aut.</sZ>
<sZ>6 aut.</sZ>
</inist:fA14>
<country>États-Unis</country>
<placeName>
<region type="state">Floride</region>
<settlement type="city">Tampa</settlement>
</placeName>
<orgName type="university">Université de Floride du Sud</orgName>
</affiliation>
<affiliation wicri:level="4">
<inist:fA14 i1="03">
<s1>Division of Infectious Diseases, H. Lee Moffitt Cancer Center and Research Institute/University of South Florida</s1>
<s2>Tampa, FL</s2>
<s3>USA</s3>
<sZ>2 aut.</sZ>
<sZ>4 aut.</sZ>
</inist:fA14>
<country>États-Unis</country>
<placeName>
<region type="state">Floride</region>
<settlement type="city">Tampa</settlement>
</placeName>
<orgName type="university">Université de Floride du Sud</orgName>
</affiliation>
</author>
<author>
<name sortKey="Field, Teresa" sort="Field, Teresa" uniqKey="Field T" first="Teresa" last="Field">Teresa Field</name>
<affiliation wicri:level="2">
<inist:fA14 i1="01">
<s1>Department of Blood and Marrow Transplantation, H. Lee Moffitt Cancer Center and Research Institute, 12902 Magnolia Drive, FOB-3</s1>
<s2>Tampa, FL 33612</s2>
<s3>USA</s3>
<sZ>1 aut.</sZ>
<sZ>2 aut.</sZ>
<sZ>3 aut.</sZ>
<sZ>4 aut.</sZ>
<sZ>5 aut.</sZ>
<sZ>6 aut.</sZ>
</inist:fA14>
<country>États-Unis</country>
<placeName>
<region type="state">Floride</region>
</placeName>
</affiliation>
<affiliation wicri:level="4">
<inist:fA14 i1="02">
<s1>Department of Oncological Sciences, H. Lee Moffitt Cancer Center and Research Institute/University of South Florida</s1>
<s2>Tampa, FL</s2>
<s3>USA</s3>
<sZ>1 aut.</sZ>
<sZ>2 aut.</sZ>
<sZ>4 aut.</sZ>
<sZ>5 aut.</sZ>
<sZ>6 aut.</sZ>
</inist:fA14>
<country>États-Unis</country>
<placeName>
<region type="state">Floride</region>
<settlement type="city">Tampa</settlement>
</placeName>
<orgName type="university">Université de Floride du Sud</orgName>
</affiliation>
</author>
<author>
<name sortKey="Sandin, Ramon" sort="Sandin, Ramon" uniqKey="Sandin R" first="Ramon" last="Sandin">Ramon Sandin</name>
<affiliation wicri:level="2">
<inist:fA14 i1="01">
<s1>Department of Blood and Marrow Transplantation, H. Lee Moffitt Cancer Center and Research Institute, 12902 Magnolia Drive, FOB-3</s1>
<s2>Tampa, FL 33612</s2>
<s3>USA</s3>
<sZ>1 aut.</sZ>
<sZ>2 aut.</sZ>
<sZ>3 aut.</sZ>
<sZ>4 aut.</sZ>
<sZ>5 aut.</sZ>
<sZ>6 aut.</sZ>
</inist:fA14>
<country>États-Unis</country>
<placeName>
<region type="state">Floride</region>
</placeName>
</affiliation>
<affiliation wicri:level="4">
<inist:fA14 i1="02">
<s1>Department of Oncological Sciences, H. Lee Moffitt Cancer Center and Research Institute/University of South Florida</s1>
<s2>Tampa, FL</s2>
<s3>USA</s3>
<sZ>1 aut.</sZ>
<sZ>2 aut.</sZ>
<sZ>4 aut.</sZ>
<sZ>5 aut.</sZ>
<sZ>6 aut.</sZ>
</inist:fA14>
<country>États-Unis</country>
<placeName>
<region type="state">Floride</region>
<settlement type="city">Tampa</settlement>
</placeName>
<orgName type="university">Université de Floride du Sud</orgName>
</affiliation>
<affiliation wicri:level="2">
<inist:fA14 i1="04">
<s1>Department of Hematopathology and Laboratory Medicine, H. Lee Moffitt Cancer Center and Research Institute</s1>
<s2>Tampa, FL</s2>
<s3>USA</s3>
<sZ>6 aut.</sZ>
</inist:fA14>
<country>États-Unis</country>
<placeName>
<region type="state">Floride</region>
</placeName>
</affiliation>
</author>
</titleStmt>
<publicationStmt>
<idno type="wicri:source">INIST</idno>
<idno type="inist">10-0161171</idno>
<date when="2010">2010</date>
<idno type="stanalyst">PASCAL 10-0161171 INIST</idno>
<idno type="RBID">Pascal:10-0161171</idno>
<idno type="wicri:Area/PascalFrancis/Corpus">001410</idno>
<idno type="wicri:Area/PascalFrancis/Curation">000A57</idno>
<idno type="wicri:Area/PascalFrancis/Checkpoint">001158</idno>
<idno type="wicri:explorRef" wicri:stream="PascalFrancis" wicri:step="Checkpoint">001158</idno>
<idno type="wicri:doubleKey">0925-5710:2010:Kharfan Dabaja M:influenza:a:pandemic</idno>
<idno type="wicri:Area/Main/Merge">003A90</idno>
<idno type="wicri:Area/Main/Curation">003919</idno>
<idno type="wicri:Area/Main/Exploration">003919</idno>
</publicationStmt>
<sourceDesc>
<biblStruct>
<analytic>
<title xml:lang="en" level="a">Influenza A/pandemic 2009/H1N1 in the setting of allogeneic hematopoietic cell transplantation: a potentially catastrophic problem in a vulnerable population</title>
<author>
<name sortKey="Kharfan Dabaja, Mohamed A" sort="Kharfan Dabaja, Mohamed A" uniqKey="Kharfan Dabaja M" first="Mohamed A." last="Kharfan-Dabaja">Mohamed A. Kharfan-Dabaja</name>
<affiliation wicri:level="2">
<inist:fA14 i1="01">
<s1>Department of Blood and Marrow Transplantation, H. Lee Moffitt Cancer Center and Research Institute, 12902 Magnolia Drive, FOB-3</s1>
<s2>Tampa, FL 33612</s2>
<s3>USA</s3>
<sZ>1 aut.</sZ>
<sZ>2 aut.</sZ>
<sZ>3 aut.</sZ>
<sZ>4 aut.</sZ>
<sZ>5 aut.</sZ>
<sZ>6 aut.</sZ>
</inist:fA14>
<country>États-Unis</country>
<placeName>
<region type="state">Floride</region>
</placeName>
</affiliation>
<affiliation wicri:level="4">
<inist:fA14 i1="02">
<s1>Department of Oncological Sciences, H. Lee Moffitt Cancer Center and Research Institute/University of South Florida</s1>
<s2>Tampa, FL</s2>
<s3>USA</s3>
<sZ>1 aut.</sZ>
<sZ>2 aut.</sZ>
<sZ>4 aut.</sZ>
<sZ>5 aut.</sZ>
<sZ>6 aut.</sZ>
</inist:fA14>
<country>États-Unis</country>
<placeName>
<region type="state">Floride</region>
<settlement type="city">Tampa</settlement>
</placeName>
<orgName type="university">Université de Floride du Sud</orgName>
</affiliation>
</author>
<author>
<name sortKey="Velez, Ana" sort="Velez, Ana" uniqKey="Velez A" first="Ana" last="Velez">Ana Velez</name>
<affiliation wicri:level="2">
<inist:fA14 i1="01">
<s1>Department of Blood and Marrow Transplantation, H. Lee Moffitt Cancer Center and Research Institute, 12902 Magnolia Drive, FOB-3</s1>
<s2>Tampa, FL 33612</s2>
<s3>USA</s3>
<sZ>1 aut.</sZ>
<sZ>2 aut.</sZ>
<sZ>3 aut.</sZ>
<sZ>4 aut.</sZ>
<sZ>5 aut.</sZ>
<sZ>6 aut.</sZ>
</inist:fA14>
<country>États-Unis</country>
<placeName>
<region type="state">Floride</region>
</placeName>
</affiliation>
<affiliation wicri:level="4">
<inist:fA14 i1="02">
<s1>Department of Oncological Sciences, H. Lee Moffitt Cancer Center and Research Institute/University of South Florida</s1>
<s2>Tampa, FL</s2>
<s3>USA</s3>
<sZ>1 aut.</sZ>
<sZ>2 aut.</sZ>
<sZ>4 aut.</sZ>
<sZ>5 aut.</sZ>
<sZ>6 aut.</sZ>
</inist:fA14>
<country>États-Unis</country>
<placeName>
<region type="state">Floride</region>
<settlement type="city">Tampa</settlement>
</placeName>
<orgName type="university">Université de Floride du Sud</orgName>
</affiliation>
<affiliation wicri:level="4">
<inist:fA14 i1="03">
<s1>Division of Infectious Diseases, H. Lee Moffitt Cancer Center and Research Institute/University of South Florida</s1>
<s2>Tampa, FL</s2>
<s3>USA</s3>
<sZ>2 aut.</sZ>
<sZ>4 aut.</sZ>
</inist:fA14>
<country>États-Unis</country>
<placeName>
<region type="state">Floride</region>
<settlement type="city">Tampa</settlement>
</placeName>
<orgName type="university">Université de Floride du Sud</orgName>
</affiliation>
</author>
<author>
<name sortKey="Richards, Karla" sort="Richards, Karla" uniqKey="Richards K" first="Karla" last="Richards">Karla Richards</name>
<affiliation wicri:level="2">
<inist:fA14 i1="01">
<s1>Department of Blood and Marrow Transplantation, H. Lee Moffitt Cancer Center and Research Institute, 12902 Magnolia Drive, FOB-3</s1>
<s2>Tampa, FL 33612</s2>
<s3>USA</s3>
<sZ>1 aut.</sZ>
<sZ>2 aut.</sZ>
<sZ>3 aut.</sZ>
<sZ>4 aut.</sZ>
<sZ>5 aut.</sZ>
<sZ>6 aut.</sZ>
</inist:fA14>
<country>États-Unis</country>
<placeName>
<region type="state">Floride</region>
</placeName>
</affiliation>
</author>
<author>
<name sortKey="Greene, John N" sort="Greene, John N" uniqKey="Greene J" first="John N." last="Greene">John N. Greene</name>
<affiliation wicri:level="2">
<inist:fA14 i1="01">
<s1>Department of Blood and Marrow Transplantation, H. Lee Moffitt Cancer Center and Research Institute, 12902 Magnolia Drive, FOB-3</s1>
<s2>Tampa, FL 33612</s2>
<s3>USA</s3>
<sZ>1 aut.</sZ>
<sZ>2 aut.</sZ>
<sZ>3 aut.</sZ>
<sZ>4 aut.</sZ>
<sZ>5 aut.</sZ>
<sZ>6 aut.</sZ>
</inist:fA14>
<country>États-Unis</country>
<placeName>
<region type="state">Floride</region>
</placeName>
</affiliation>
<affiliation wicri:level="4">
<inist:fA14 i1="02">
<s1>Department of Oncological Sciences, H. Lee Moffitt Cancer Center and Research Institute/University of South Florida</s1>
<s2>Tampa, FL</s2>
<s3>USA</s3>
<sZ>1 aut.</sZ>
<sZ>2 aut.</sZ>
<sZ>4 aut.</sZ>
<sZ>5 aut.</sZ>
<sZ>6 aut.</sZ>
</inist:fA14>
<country>États-Unis</country>
<placeName>
<region type="state">Floride</region>
<settlement type="city">Tampa</settlement>
</placeName>
<orgName type="university">Université de Floride du Sud</orgName>
</affiliation>
<affiliation wicri:level="4">
<inist:fA14 i1="03">
<s1>Division of Infectious Diseases, H. Lee Moffitt Cancer Center and Research Institute/University of South Florida</s1>
<s2>Tampa, FL</s2>
<s3>USA</s3>
<sZ>2 aut.</sZ>
<sZ>4 aut.</sZ>
</inist:fA14>
<country>États-Unis</country>
<placeName>
<region type="state">Floride</region>
<settlement type="city">Tampa</settlement>
</placeName>
<orgName type="university">Université de Floride du Sud</orgName>
</affiliation>
</author>
<author>
<name sortKey="Field, Teresa" sort="Field, Teresa" uniqKey="Field T" first="Teresa" last="Field">Teresa Field</name>
<affiliation wicri:level="2">
<inist:fA14 i1="01">
<s1>Department of Blood and Marrow Transplantation, H. Lee Moffitt Cancer Center and Research Institute, 12902 Magnolia Drive, FOB-3</s1>
<s2>Tampa, FL 33612</s2>
<s3>USA</s3>
<sZ>1 aut.</sZ>
<sZ>2 aut.</sZ>
<sZ>3 aut.</sZ>
<sZ>4 aut.</sZ>
<sZ>5 aut.</sZ>
<sZ>6 aut.</sZ>
</inist:fA14>
<country>États-Unis</country>
<placeName>
<region type="state">Floride</region>
</placeName>
</affiliation>
<affiliation wicri:level="4">
<inist:fA14 i1="02">
<s1>Department of Oncological Sciences, H. Lee Moffitt Cancer Center and Research Institute/University of South Florida</s1>
<s2>Tampa, FL</s2>
<s3>USA</s3>
<sZ>1 aut.</sZ>
<sZ>2 aut.</sZ>
<sZ>4 aut.</sZ>
<sZ>5 aut.</sZ>
<sZ>6 aut.</sZ>
</inist:fA14>
<country>États-Unis</country>
<placeName>
<region type="state">Floride</region>
<settlement type="city">Tampa</settlement>
</placeName>
<orgName type="university">Université de Floride du Sud</orgName>
</affiliation>
</author>
<author>
<name sortKey="Sandin, Ramon" sort="Sandin, Ramon" uniqKey="Sandin R" first="Ramon" last="Sandin">Ramon Sandin</name>
<affiliation wicri:level="2">
<inist:fA14 i1="01">
<s1>Department of Blood and Marrow Transplantation, H. Lee Moffitt Cancer Center and Research Institute, 12902 Magnolia Drive, FOB-3</s1>
<s2>Tampa, FL 33612</s2>
<s3>USA</s3>
<sZ>1 aut.</sZ>
<sZ>2 aut.</sZ>
<sZ>3 aut.</sZ>
<sZ>4 aut.</sZ>
<sZ>5 aut.</sZ>
<sZ>6 aut.</sZ>
</inist:fA14>
<country>États-Unis</country>
<placeName>
<region type="state">Floride</region>
</placeName>
</affiliation>
<affiliation wicri:level="4">
<inist:fA14 i1="02">
<s1>Department of Oncological Sciences, H. Lee Moffitt Cancer Center and Research Institute/University of South Florida</s1>
<s2>Tampa, FL</s2>
<s3>USA</s3>
<sZ>1 aut.</sZ>
<sZ>2 aut.</sZ>
<sZ>4 aut.</sZ>
<sZ>5 aut.</sZ>
<sZ>6 aut.</sZ>
</inist:fA14>
<country>États-Unis</country>
<placeName>
<region type="state">Floride</region>
<settlement type="city">Tampa</settlement>
</placeName>
<orgName type="university">Université de Floride du Sud</orgName>
</affiliation>
<affiliation wicri:level="2">
<inist:fA14 i1="04">
<s1>Department of Hematopathology and Laboratory Medicine, H. Lee Moffitt Cancer Center and Research Institute</s1>
<s2>Tampa, FL</s2>
<s3>USA</s3>
<sZ>6 aut.</sZ>
</inist:fA14>
<country>États-Unis</country>
<placeName>
<region type="state">Floride</region>
</placeName>
</affiliation>
</author>
</analytic>
<series>
<title level="j" type="main">International journal of hematology</title>
<title level="j" type="abbreviated">Int. j. hematol.</title>
<idno type="ISSN">0925-5710</idno>
<imprint>
<date when="2010">2010</date>
</imprint>
</series>
</biblStruct>
</sourceDesc>
<seriesStmt>
<title level="j" type="main">International journal of hematology</title>
<title level="j" type="abbreviated">Int. j. hematol.</title>
<idno type="ISSN">0925-5710</idno>
</seriesStmt>
</fileDesc>
<profileDesc>
<textClass>
<keywords scheme="KwdEn" xml:lang="en">
<term>Allogeneic hematopoietic stem cell transplantation</term>
<term>H1N1 influenza</term>
<term>Hematology</term>
<term>Hematopoietic cell</term>
<term>Homograft</term>
<term>Human</term>
<term>Influenza A</term>
<term>Stem cell</term>
</keywords>
<keywords scheme="Pascal" xml:lang="fr">
<term>Grippe A</term>
<term>Homogreffe</term>
<term>Cellule hématopoïétique</term>
<term>Cellule souche</term>
<term>Homme</term>
<term>Hématologie</term>
<term>Grippe H1N1</term>
<term>Allogreffe de cellules souches hématopoïétiques</term>
</keywords>
<keywords scheme="Wicri" type="topic" xml:lang="fr">
<term>Cellule souche</term>
<term>Homme</term>
</keywords>
</textClass>
</profileDesc>
</teiHeader>
<front>
<div type="abstract" xml:lang="en">We describe Influenza A/pandemic 2009/H1N1 in two allogeneic hematopoietic cell transplantation recipients. The main presentation in both cases consisted of flu-like symptoms manifesting as, fever, arthralgias and myalgias. The virus was isolated in one case from a throat swab and in another case following a bronchoalveolar lavage. Both patients received oseltamivir at a dose of 75 mg orally twice day. The dose of oseltamivir was increased to 150 mg twice per day due to the lack of improvement or progression of symptoms. In one case, clinical symptoms resolved without sequelae. In the second case, pulmonary symptomatology continued to deteriorate, despite aggressive polymicrobial treatment, requiring mechanical ventilation and ultimately the patient died from respiratory failure. These cases highlight the potentially serious effect of the ongoing Influenza A/pandemic 2009/ H1N1 pandemic in this very vulnerable population and the urgent need to establish emergency preparedness strategies by oncology and bone marrow transplantation staff to face this serious healthcare challenge.</div>
</front>
</TEI>
<affiliations>
<list>
<country>
<li>États-Unis</li>
</country>
<region>
<li>Floride</li>
</region>
<settlement>
<li>Tampa</li>
</settlement>
<orgName>
<li>Université de Floride du Sud</li>
</orgName>
</list>
<tree>
<country name="États-Unis">
<region name="Floride">
<name sortKey="Kharfan Dabaja, Mohamed A" sort="Kharfan Dabaja, Mohamed A" uniqKey="Kharfan Dabaja M" first="Mohamed A." last="Kharfan-Dabaja">Mohamed A. Kharfan-Dabaja</name>
</region>
<name sortKey="Field, Teresa" sort="Field, Teresa" uniqKey="Field T" first="Teresa" last="Field">Teresa Field</name>
<name sortKey="Field, Teresa" sort="Field, Teresa" uniqKey="Field T" first="Teresa" last="Field">Teresa Field</name>
<name sortKey="Greene, John N" sort="Greene, John N" uniqKey="Greene J" first="John N." last="Greene">John N. Greene</name>
<name sortKey="Greene, John N" sort="Greene, John N" uniqKey="Greene J" first="John N." last="Greene">John N. Greene</name>
<name sortKey="Greene, John N" sort="Greene, John N" uniqKey="Greene J" first="John N." last="Greene">John N. Greene</name>
<name sortKey="Kharfan Dabaja, Mohamed A" sort="Kharfan Dabaja, Mohamed A" uniqKey="Kharfan Dabaja M" first="Mohamed A." last="Kharfan-Dabaja">Mohamed A. Kharfan-Dabaja</name>
<name sortKey="Richards, Karla" sort="Richards, Karla" uniqKey="Richards K" first="Karla" last="Richards">Karla Richards</name>
<name sortKey="Sandin, Ramon" sort="Sandin, Ramon" uniqKey="Sandin R" first="Ramon" last="Sandin">Ramon Sandin</name>
<name sortKey="Sandin, Ramon" sort="Sandin, Ramon" uniqKey="Sandin R" first="Ramon" last="Sandin">Ramon Sandin</name>
<name sortKey="Sandin, Ramon" sort="Sandin, Ramon" uniqKey="Sandin R" first="Ramon" last="Sandin">Ramon Sandin</name>
<name sortKey="Velez, Ana" sort="Velez, Ana" uniqKey="Velez A" first="Ana" last="Velez">Ana Velez</name>
<name sortKey="Velez, Ana" sort="Velez, Ana" uniqKey="Velez A" first="Ana" last="Velez">Ana Velez</name>
<name sortKey="Velez, Ana" sort="Velez, Ana" uniqKey="Velez A" first="Ana" last="Velez">Ana Velez</name>
</country>
</tree>
</affiliations>
</record>

Pour manipuler ce document sous Unix (Dilib)

EXPLOR_STEP=$WICRI_ROOT/Sante/explor/PandemieGrippaleV1/Data/Main/Exploration
HfdSelect -h $EXPLOR_STEP/biblio.hfd -nk 003919 | SxmlIndent | more

Ou

HfdSelect -h $EXPLOR_AREA/Data/Main/Exploration/biblio.hfd -nk 003919 | SxmlIndent | more

Pour mettre un lien sur cette page dans le réseau Wicri

{{Explor lien
   |wiki=    Sante
   |area=    PandemieGrippaleV1
   |flux=    Main
   |étape=   Exploration
   |type=    RBID
   |clé=     Pascal:10-0161171
   |texte=   Influenza A/pandemic 2009/H1N1 in the setting of allogeneic hematopoietic cell transplantation: a potentially catastrophic problem in a vulnerable population
}}

Wicri

This area was generated with Dilib version V0.6.34.
Data generation: Wed Jun 10 11:04:28 2020. Site generation: Sun Mar 28 09:10:28 2021