PandemieGrippaleV1, PascalFrancis, Corpus, bibRecord, 001410

Influenza A/pandemic 2009/H1N1 in the setting of allogeneic hematopoietic cell transplantation: a potentially catastrophic problem in a vulnerable population

Identifieur interne : 001410 ( PascalFrancis/Corpus ); précédent : 001409; suivant : 001411

Influenza A/pandemic 2009/H1N1 in the setting of allogeneic hematopoietic cell transplantation: a potentially catastrophic problem in a vulnerable population

Auteurs : Mohamed A. Kharfan-Dabaja ; Ana Velez ; Karla Richards ; John N. Greene ; Teresa Field ; Ramon Sandin

Source :

International journal of hematology [ 0925-5710 ] ; 2010.

RBID : Pascal:10-0161171

Descripteurs français

Pascal (Inist)
- Grippe A, Homogreffe, Cellule hématopoïétique, Cellule souche, Homme, Hématologie, Grippe H1N1, Allogreffe de cellules souches hématopoïétiques.

English descriptors

KwdEn :
- Allogeneic hematopoietic stem cell transplantation, H1N1 influenza, Hematology, Hematopoietic cell, Homograft, Human, Influenza A, Stem cell.

Abstract

We describe Influenza A/pandemic 2009/H1N1 in two allogeneic hematopoietic cell transplantation recipients. The main presentation in both cases consisted of flu-like symptoms manifesting as, fever, arthralgias and myalgias. The virus was isolated in one case from a throat swab and in another case following a bronchoalveolar lavage. Both patients received oseltamivir at a dose of 75 mg orally twice day. The dose of oseltamivir was increased to 150 mg twice per day due to the lack of improvement or progression of symptoms. In one case, clinical symptoms resolved without sequelae. In the second case, pulmonary symptomatology continued to deteriorate, despite aggressive polymicrobial treatment, requiring mechanical ventilation and ultimately the patient died from respiratory failure. These cases highlight the potentially serious effect of the ongoing Influenza A/pandemic 2009/ H1N1 pandemic in this very vulnerable population and the urgent need to establish emergency preparedness strategies by oncology and bone marrow transplantation staff to face this serious healthcare challenge.

Notice en format standard (ISO 2709)

Pour connaître la documentation sur le format Inist Standard.

A01	`01`	`1`		`@0 0925-5710`
A03		`1`		`@0 Int. j. hematol.`
A05				`@2 91`
A06				`@2 1`
A08	`01`	`1`	`ENG`	`@1 Influenza A/pandemic 2009/H1N1 in the setting of allogeneic hematopoietic cell transplantation: a potentially catastrophic problem in a vulnerable population`
A11	`01`	`1`		`@1 KHARFAN-DABAJA (Mohamed A.)`
A11	`02`	`1`		`@1 VELEZ (Ana)`
A11	`03`	`1`		`@1 RICHARDS (Karla)`
A11	`04`	`1`		`@1 GREENE (John N.)`
A11	`05`	`1`		`@1 FIELD (Teresa)`
A11	`06`	`1`		`@1 SANDIN (Ramon)`
A14	`01`			`@1 Department of Blood and Marrow Transplantation, H. Lee Moffitt Cancer Center and Research Institute, 12902 Magnolia Drive, FOB-3 @2 Tampa, FL 33612 @3 USA @Z 1 aut. @Z 2 aut. @Z 3 aut. @Z 4 aut. @Z 5 aut. @Z 6 aut.`
A14	`02`			`@1 Department of Oncological Sciences, H. Lee Moffitt Cancer Center and Research Institute/University of South Florida @2 Tampa, FL @3 USA @Z 1 aut. @Z 2 aut. @Z 4 aut. @Z 5 aut. @Z 6 aut.`
A14	`03`			`@1 Division of Infectious Diseases, H. Lee Moffitt Cancer Center and Research Institute/University of South Florida @2 Tampa, FL @3 USA @Z 2 aut. @Z 4 aut.`
A14	`04`			`@1 Department of Hematopathology and Laboratory Medicine, H. Lee Moffitt Cancer Center and Research Institute @2 Tampa, FL @3 USA @Z 6 aut.`
A20				`@1 124-127`
A21				`@1 2010`
A23	`01`			`@0 ENG`
A43	`01`			`@1 INIST @2 19540 @5 354000181634600170`
A44				`@0 0000 @1 © 2010 INIST-CNRS. All rights reserved.`
A45				`@0 18 ref.`
A47	`01`	`1`		`@0 10-0161171`
A60				`@1 P @3 EC`
A61				`@0 A`
A64	`01`	`1`		`@0 International journal of hematology`
A66	`01`			`@0 DEU`
C01	`01`		`ENG`	@0 We describe Influenza A/pandemic 2009/H1N1 in two allogeneic hematopoietic cell transplantation recipients. The main presentation in both cases consisted of flu-like symptoms manifesting as, fever, arthralgias and myalgias. The virus was isolated in one case from a throat swab and in another case following a bronchoalveolar lavage. Both patients received oseltamivir at a dose of 75 mg orally twice day. The dose of oseltamivir was increased to 150 mg twice per day due to the lack of improvement or progression of symptoms. In one case, clinical symptoms resolved without sequelae. In the second case, pulmonary symptomatology continued to deteriorate, despite aggressive polymicrobial treatment, requiring mechanical ventilation and ultimately the patient died from respiratory failure. These cases highlight the potentially serious effect of the ongoing Influenza A/pandemic 2009/ H1N1 pandemic in this very vulnerable population and the urgent need to establish emergency preparedness strategies by oncology and bone marrow transplantation staff to face this serious healthcare challenge.
C02	`01`	`X`		`@0 002B19`
C02	`02`	`X`		`@0 002B05C02C`
C03	`01`	`X`	`FRE`	`@0 Grippe A @5 09`
C03	`01`	`X`	`ENG`	`@0 Influenza A @5 09`
C03	`01`	`X`	`SPA`	`@0 Gripe A @5 09`
C03	`02`	`X`	`FRE`	`@0 Homogreffe @5 10`
C03	`02`	`X`	`ENG`	`@0 Homograft @5 10`
C03	`02`	`X`	`SPA`	`@0 Homoinjerto @5 10`
C03	`03`	`X`	`FRE`	`@0 Cellule hématopoïétique @5 11`
C03	`03`	`X`	`ENG`	`@0 Hematopoietic cell @5 11`
C03	`03`	`X`	`SPA`	`@0 Célula hematopoyética @5 11`
C03	`04`	`X`	`FRE`	`@0 Cellule souche @5 12`
C03	`04`	`X`	`ENG`	`@0 Stem cell @5 12`
C03	`04`	`X`	`SPA`	`@0 Célula primitiva @5 12`
C03	`05`	`X`	`FRE`	`@0 Homme @5 13`
C03	`05`	`X`	`ENG`	`@0 Human @5 13`
C03	`05`	`X`	`SPA`	`@0 Hombre @5 13`
C03	`06`	`X`	`FRE`	`@0 Hématologie @5 14`
C03	`06`	`X`	`ENG`	`@0 Hematology @5 14`
C03	`06`	`X`	`SPA`	`@0 Hematología @5 14`
C03	`07`	`X`	`FRE`	`@0 Grippe H1N1 @4 CD @5 96`
C03	`07`	`X`	`ENG`	`@0 H1N1 influenza @4 CD @5 96`
C03	`08`	`X`	`FRE`	`@0 Allogreffe de cellules souches hématopoïétiques @4 CD @5 97`
C03	`08`	`X`	`ENG`	`@0 Allogeneic hematopoietic stem cell transplantation @4 CD @5 97`
C07	`01`	`X`	`FRE`	`@0 Virose`
C07	`01`	`X`	`ENG`	`@0 Viral disease`
C07	`01`	`X`	`SPA`	`@0 Virosis`
C07	`02`	`X`	`FRE`	`@0 Infection`
C07	`02`	`X`	`ENG`	`@0 Infection`
C07	`02`	`X`	`SPA`	`@0 Infección`
C07	`03`	`X`	`FRE`	`@0 Pathologie de l'appareil respiratoire @5 37`
C07	`03`	`X`	`ENG`	`@0 Respiratory disease @5 37`
C07	`03`	`X`	`SPA`	`@0 Aparato respiratorio patología @5 37`
C07	`04`	`X`	`FRE`	`@0 Greffe @5 39`
C07	`04`	`X`	`ENG`	`@0 Graft @5 39`
C07	`04`	`X`	`SPA`	`@0 Injerto @5 39`
N21				`@1 102`
N44	`01`			`@1 OTO`
N82				`@1 OTO`

Format Inist (serveur)

NO :	PASCAL 10-0161171 INIST
ET :	Influenza A/pandemic 2009/H1N1 in the setting of allogeneic hematopoietic cell transplantation: a potentially catastrophic problem in a vulnerable population
AU :	KHARFAN-DABAJA (Mohamed A.); VELEZ (Ana); RICHARDS (Karla); GREENE (John N.); FIELD (Teresa); SANDIN (Ramon)
AF :	Department of Blood and Marrow Transplantation, H. Lee Moffitt Cancer Center and Research Institute, 12902 Magnolia Drive, FOB-3/Tampa, FL 33612/Etats-Unis (1 aut., 2 aut., 3 aut., 4 aut., 5 aut., 6 aut.); Department of Oncological Sciences, H. Lee Moffitt Cancer Center and Research Institute/University of South Florida/Tampa, FL/Etats-Unis (1 aut., 2 aut., 4 aut., 5 aut., 6 aut.); Division of Infectious Diseases, H. Lee Moffitt Cancer Center and Research Institute/University of South Florida/Tampa, FL/Etats-Unis (2 aut., 4 aut.); Department of Hematopathology and Laboratory Medicine, H. Lee Moffitt Cancer Center and Research Institute/Tampa, FL/Etats-Unis (6 aut.)
DT :	Publication en série; Etude de cas, cas et faits cliniques; Niveau analytique
SO :	International journal of hematology; ISSN 0925-5710; Allemagne; Da. 2010; Vol. 91; No. 1; Pp. 124-127; Bibl. 18 ref.
LA :	Anglais
EA :	We describe Influenza A/pandemic 2009/H1N1 in two allogeneic hematopoietic cell transplantation recipients. The main presentation in both cases consisted of flu-like symptoms manifesting as, fever, arthralgias and myalgias. The virus was isolated in one case from a throat swab and in another case following a bronchoalveolar lavage. Both patients received oseltamivir at a dose of 75 mg orally twice day. The dose of oseltamivir was increased to 150 mg twice per day due to the lack of improvement or progression of symptoms. In one case, clinical symptoms resolved without sequelae. In the second case, pulmonary symptomatology continued to deteriorate, despite aggressive polymicrobial treatment, requiring mechanical ventilation and ultimately the patient died from respiratory failure. These cases highlight the potentially serious effect of the ongoing Influenza A/pandemic 2009/ H1N1 pandemic in this very vulnerable population and the urgent need to establish emergency preparedness strategies by oncology and bone marrow transplantation staff to face this serious healthcare challenge.
CC :	002B19; 002B05C02C
FD :	Grippe A; Homogreffe; Cellule hématopoïétique; Cellule souche; Homme; Hématologie; Grippe H1N1; Allogreffe de cellules souches hématopoïétiques
FG :	Virose; Infection; Pathologie de l'appareil respiratoire; Greffe
ED :	Influenza A; Homograft; Hematopoietic cell; Stem cell; Human; Hematology; H1N1 influenza; Allogeneic hematopoietic stem cell transplantation
EG :	Viral disease; Infection; Respiratory disease; Graft
SD :	Gripe A; Homoinjerto; Célula hematopoyética; Célula primitiva; Hombre; Hematología
LO :	INIST-19540.354000181634600170
ID :	10-0161171

Links to Exploration step

Pascal:10-0161171

Le document en format XML

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<sourceDesc><biblStruct><analytic><title xml:lang="en" level="a">Influenza A/pandemic 2009/H1N1 in the setting of allogeneic hematopoietic cell transplantation: a potentially catastrophic problem in a vulnerable population</title>
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<author><name sortKey="Greene, John N" sort="Greene, John N" uniqKey="Greene J" first="John N." last="Greene">John N. Greene</name>
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<author><name sortKey="Field, Teresa" sort="Field, Teresa" uniqKey="Field T" first="Teresa" last="Field">Teresa Field</name>
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<author><name sortKey="Sandin, Ramon" sort="Sandin, Ramon" uniqKey="Sandin R" first="Ramon" last="Sandin">Ramon Sandin</name>
<affiliation><inist:fA14 i1="01"><s1>Department of Blood and Marrow Transplantation, H. Lee Moffitt Cancer Center and Research Institute, 12902 Magnolia Drive, FOB-3</s1>
<s2>Tampa, FL 33612</s2>
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<sZ>1 aut.</sZ>
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<sZ>4 aut.</sZ>
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<affiliation><inist:fA14 i1="02"><s1>Department of Oncological Sciences, H. Lee Moffitt Cancer Center and Research Institute/University of South Florida</s1>
<s2>Tampa, FL</s2>
<s3>USA</s3>
<sZ>1 aut.</sZ>
<sZ>2 aut.</sZ>
<sZ>4 aut.</sZ>
<sZ>5 aut.</sZ>
<sZ>6 aut.</sZ>
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<affiliation><inist:fA14 i1="04"><s1>Department of Hematopathology and Laboratory Medicine, H. Lee Moffitt Cancer Center and Research Institute</s1>
<s2>Tampa, FL</s2>
<s3>USA</s3>
<sZ>6 aut.</sZ>
</inist:fA14>
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<series><title level="j" type="main">International journal of hematology</title>
<title level="j" type="abbreviated">Int. j. hematol.</title>
<idno type="ISSN">0925-5710</idno>
<imprint><date when="2010">2010</date>
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<seriesStmt><title level="j" type="main">International journal of hematology</title>
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<profileDesc><textClass><keywords scheme="KwdEn" xml:lang="en"><term>Allogeneic hematopoietic stem cell transplantation</term>
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<front><div type="abstract" xml:lang="en">We describe Influenza A/pandemic 2009/H1N1 in two allogeneic hematopoietic cell transplantation recipients. The main presentation in both cases consisted of flu-like symptoms manifesting as, fever, arthralgias and myalgias. The virus was isolated in one case from a throat swab and in another case following a bronchoalveolar lavage. Both patients received oseltamivir at a dose of 75 mg orally twice day. The dose of oseltamivir was increased to 150 mg twice per day due to the lack of improvement or progression of symptoms. In one case, clinical symptoms resolved without sequelae. In the second case, pulmonary symptomatology continued to deteriorate, despite aggressive polymicrobial treatment, requiring mechanical ventilation and ultimately the patient died from respiratory failure. These cases highlight the potentially serious effect of the ongoing Influenza A/pandemic 2009/ H1N1 pandemic in this very vulnerable population and the urgent need to establish emergency preparedness strategies by oncology and bone marrow transplantation staff to face this serious healthcare challenge.</div>
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<sZ>1 aut.</sZ>
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<sZ>5 aut.</sZ>
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<sZ>1 aut.</sZ>
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<ET>Influenza A/pandemic 2009/H1N1 in the setting of allogeneic hematopoietic cell transplantation: a potentially catastrophic problem in a vulnerable population</ET>
<AU>KHARFAN-DABAJA (Mohamed A.); VELEZ (Ana); RICHARDS (Karla); GREENE (John N.); FIELD (Teresa); SANDIN (Ramon)</AU>
<AF>Department of Blood and Marrow Transplantation, H. Lee Moffitt Cancer Center and Research Institute, 12902 Magnolia Drive, FOB-3/Tampa, FL 33612/Etats-Unis (1 aut., 2 aut., 3 aut., 4 aut., 5 aut., 6 aut.); Department of Oncological Sciences, H. Lee Moffitt Cancer Center and Research Institute/University of South Florida/Tampa, FL/Etats-Unis (1 aut., 2 aut., 4 aut., 5 aut., 6 aut.); Division of Infectious Diseases, H. Lee Moffitt Cancer Center and Research Institute/University of South Florida/Tampa, FL/Etats-Unis (2 aut., 4 aut.); Department of Hematopathology and Laboratory Medicine, H. Lee Moffitt Cancer Center and Research Institute/Tampa, FL/Etats-Unis (6 aut.)</AF>
<DT>Publication en série; Etude de cas, cas et faits cliniques; Niveau analytique</DT>
<SO>International journal of hematology; ISSN 0925-5710; Allemagne; Da. 2010; Vol. 91; No. 1; Pp. 124-127; Bibl. 18 ref.</SO>
<LA>Anglais</LA>
<EA>We describe Influenza A/pandemic 2009/H1N1 in two allogeneic hematopoietic cell transplantation recipients. The main presentation in both cases consisted of flu-like symptoms manifesting as, fever, arthralgias and myalgias. The virus was isolated in one case from a throat swab and in another case following a bronchoalveolar lavage. Both patients received oseltamivir at a dose of 75 mg orally twice day. The dose of oseltamivir was increased to 150 mg twice per day due to the lack of improvement or progression of symptoms. In one case, clinical symptoms resolved without sequelae. In the second case, pulmonary symptomatology continued to deteriorate, despite aggressive polymicrobial treatment, requiring mechanical ventilation and ultimately the patient died from respiratory failure. These cases highlight the potentially serious effect of the ongoing Influenza A/pandemic 2009/ H1N1 pandemic in this very vulnerable population and the urgent need to establish emergency preparedness strategies by oncology and bone marrow transplantation staff to face this serious healthcare challenge.</EA>
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Influenza A/pandemic 2009/H1N1 in the setting of allogeneic hematopoietic cell transplantation: a potentially catastrophic problem in a vulnerable population

Influenza A/pandemic 2009/H1N1 in the setting of allogeneic hematopoietic cell transplantation: a potentially catastrophic problem in a vulnerable population

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