2009 H1N1 Influenza: A Twenty-First Century Pandemic With Roots in the Early Twentieth Century
Identifieur interne : 003B38 ( Main/Exploration ); précédent : 003B37; suivant : 003B392009 H1N1 Influenza: A Twenty-First Century Pandemic With Roots in the Early Twentieth Century
Auteurs : Monica M. Farley [États-Unis]Source :
- The American journal of the medical sciences [ 0002-9629 ] ; 2010.
Descripteurs français
- KwdFr :
- Flambées de maladies, Grippe humaine (), Grippe humaine (diagnostic), Grippe humaine (virologie), Grippe humaine (épidémiologie), Humains, Sous-type H1N1 du virus de la grippe A (immunologie), Sous-type H1N1 du virus de la grippe A (isolement et purification), Vaccins antigrippaux (administration et posologie).
- MESH :
- administration et posologie : Vaccins antigrippaux.
- diagnostic : Grippe humaine.
- immunologie : Sous-type H1N1 du virus de la grippe A.
- isolement et purification : Sous-type H1N1 du virus de la grippe A.
- virologie : Grippe humaine.
- épidémiologie : Grippe humaine.
- Pascal (Inist)
- Wicri :
- topic : Santé publique, Porcin, Médecine.
English descriptors
- KwdEn :
- 2009, Animal, Disease Outbreaks, Early, H1N1 influenza, Hemagglutinin, Humans, Influenza A, Influenza A Virus, H1N1 Subtype (immunology), Influenza A Virus, H1N1 Subtype (isolation & purification), Influenza Vaccines (administration & dosage), Influenza, Human (diagnosis), Influenza, Human (epidemiology), Influenza, Human (prevention & control), Influenza, Human (virology), Medicine, Public health, Root, Swine, World.
- MESH :
- chemical , administration & dosage : Influenza Vaccines.
- diagnosis : Influenza, Human.
- epidemiology : Influenza, Human.
- immunology : Influenza A Virus, H1N1 Subtype.
- isolation & purification : Influenza A Virus, H1N1 Subtype.
- prevention & control : Influenza, Human.
- virology : Influenza, Human.
- Disease Outbreaks, Humans.
Abstract
A swine-origin H1N1 triple-reassortant influenza A virus found to be a distant relative of the 1918 "Spanish flu" virus emerged in April 2009 to give rise to the first influenza pandemic of the 21st century. Although disease was generally mild and similar to seasonal influenza, severe manifestations including respiratory failure were noted in some, particularly those with underlying conditions such as asthma, pregnancy and immunosuppression. Children and younger adults accounted for most cases, hospitalizations and deaths. A reverse transcriptase-polymerase chain reaction assay was superior to antigen-based rapid tests for diagnosis. All 2009 H1N1 pandemic influenza strains were susceptible to 1 or more neuraminidase inhibitors. Monovalent, unadjuvanted 2009 H1N1 vaccines were licensed in the United States in September 2009 and initially targeted to younger individuals, pregnant women, caretakers of infants and healthcare providers. The 2009 H1N1 pandemic highlights the need for modernization of influenza vaccines, improved diagnostics and more rigorous evaluation of mitigation strategies.
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Affiliations:
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Le document en format XML
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Farley</name><affiliation wicri:level="2"><inist:fA14 i1="01"><s1>Department of Medicine, Division of Infectious Diseases, Emory University School of Medicine and the Atlanta VA Medical Center</s1><s2>Atlanta, Georgia</s2><s3>USA</s3><sZ>1 aut.</sZ></inist:fA14><country>États-Unis</country><placeName><region type="state">Géorgie (États-Unis)</region></placeName></affiliation></author></analytic><series><title level="j" type="main">The American journal of the medical sciences</title><title level="j" type="abbreviated">Am. j. med. sci.</title><idno type="ISSN">0002-9629</idno><imprint><date when="2010">2010</date></imprint></series></biblStruct></sourceDesc><seriesStmt><title level="j" type="main">The American journal of the medical sciences</title><title level="j" type="abbreviated">Am. j. med. sci.</title><idno type="ISSN">0002-9629</idno></seriesStmt></fileDesc><profileDesc><textClass><keywords scheme="KwdEn" xml:lang="en"><term>2009</term><term>Animal</term><term>Disease Outbreaks</term><term>Early</term><term>H1N1 influenza</term><term>Hemagglutinin</term><term>Humans</term><term>Influenza A</term><term>Influenza A Virus, H1N1 Subtype (immunology)</term><term>Influenza A Virus, H1N1 Subtype (isolation & purification)</term><term>Influenza Vaccines (administration & dosage)</term><term>Influenza, Human (diagnosis)</term><term>Influenza, Human (epidemiology)</term><term>Influenza, Human (prevention & control)</term><term>Influenza, Human (virology)</term><term>Medicine</term><term>Public health</term><term>Root</term><term>Swine</term><term>World</term></keywords><keywords scheme="KwdFr" xml:lang="fr"><term>Flambées de maladies</term><term>Grippe humaine ()</term><term>Grippe humaine (diagnostic)</term><term>Grippe humaine (virologie)</term><term>Grippe humaine (épidémiologie)</term><term>Humains</term><term>Sous-type H1N1 du virus de la grippe A (immunologie)</term><term>Sous-type H1N1 du virus de la grippe A (isolement et purification)</term><term>Vaccins antigrippaux (administration et posologie)</term></keywords><keywords scheme="MESH" type="chemical" qualifier="administration & dosage" xml:lang="en"><term>Influenza Vaccines</term></keywords><keywords scheme="MESH" qualifier="administration et posologie" xml:lang="fr"><term>Vaccins antigrippaux</term></keywords><keywords scheme="MESH" qualifier="diagnosis" xml:lang="en"><term>Influenza, Human</term></keywords><keywords scheme="MESH" qualifier="diagnostic" xml:lang="fr"><term>Grippe humaine</term></keywords><keywords scheme="MESH" qualifier="epidemiology" xml:lang="en"><term>Influenza, Human</term></keywords><keywords scheme="MESH" qualifier="immunologie" xml:lang="fr"><term>Sous-type H1N1 du virus de la grippe A</term></keywords><keywords scheme="MESH" qualifier="immunology" xml:lang="en"><term>Influenza A Virus, H1N1 Subtype</term></keywords><keywords scheme="MESH" qualifier="isolation & purification" xml:lang="en"><term>Influenza A Virus, H1N1 Subtype</term></keywords><keywords scheme="MESH" qualifier="isolement et purification" xml:lang="fr"><term>Sous-type H1N1 du virus de la grippe A</term></keywords><keywords scheme="MESH" qualifier="prevention & control" xml:lang="en"><term>Influenza, Human</term></keywords><keywords scheme="MESH" qualifier="virologie" xml:lang="fr"><term>Grippe humaine</term></keywords><keywords scheme="MESH" qualifier="virology" xml:lang="en"><term>Influenza, Human</term></keywords><keywords scheme="MESH" qualifier="épidémiologie" xml:lang="fr"><term>Grippe humaine</term></keywords><keywords scheme="MESH" xml:lang="en"><term>Disease Outbreaks</term><term>Humans</term></keywords><keywords scheme="Pascal" xml:lang="fr"><term>2009</term><term>Flambées de maladies</term><term>Grippe humaine</term><term>Humains</term><term>Santé publique</term><term>Grippe A</term><term>Monde</term><term>Racine</term><term>Précoce</term><term>Porcin</term><term>Animal</term><term>Hémagglutinine</term><term>Médecine</term><term>Pandémie</term><term>Grippe H1N1</term></keywords><keywords scheme="Wicri" type="topic" xml:lang="fr"><term>Santé publique</term><term>Porcin</term><term>Médecine</term></keywords></textClass></profileDesc></teiHeader><front><div type="abstract" xml:lang="en">A swine-origin H1N1 triple-reassortant influenza A virus found to be a distant relative of the 1918 "Spanish flu" virus emerged in April 2009 to give rise to the first influenza pandemic of the 21st century. Although disease was generally mild and similar to seasonal influenza, severe manifestations including respiratory failure were noted in some, particularly those with underlying conditions such as asthma, pregnancy and immunosuppression. Children and younger adults accounted for most cases, hospitalizations and deaths. A reverse transcriptase-polymerase chain reaction assay was superior to antigen-based rapid tests for diagnosis. All 2009 H1N1 pandemic influenza strains were susceptible to 1 or more neuraminidase inhibitors. Monovalent, unadjuvanted 2009 H1N1 vaccines were licensed in the United States in September 2009 and initially targeted to younger individuals, pregnant women, caretakers of infants and healthcare providers. The 2009 H1N1 pandemic highlights the need for modernization of influenza vaccines, improved diagnostics and more rigorous evaluation of mitigation strategies.</div></front></TEI><affiliations><list><country><li>États-Unis</li></country><region><li>Géorgie (États-Unis)</li></region></list><tree><country name="États-Unis"><region name="Géorgie (États-Unis)"><name sortKey="Farley, Monica M" sort="Farley, Monica M" uniqKey="Farley M" first="Monica M." last="Farley">Monica M. Farley</name></region></country></tree></affiliations></record>Pour manipuler ce document sous Unix (Dilib)
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