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2009 H1N1 Influenza: A Twenty-First Century Pandemic With Roots in the Early Twentieth Century

Identifieur interne : 000D58 ( PascalFrancis/Curation ); précédent : 000D57; suivant : 000D59

2009 H1N1 Influenza: A Twenty-First Century Pandemic With Roots in the Early Twentieth Century

Auteurs : Monica M. Farley [États-Unis]

Source :

RBID : Pascal:10-0457455

Descripteurs français

English descriptors

Abstract

A swine-origin H1N1 triple-reassortant influenza A virus found to be a distant relative of the 1918 "Spanish flu" virus emerged in April 2009 to give rise to the first influenza pandemic of the 21st century. Although disease was generally mild and similar to seasonal influenza, severe manifestations including respiratory failure were noted in some, particularly those with underlying conditions such as asthma, pregnancy and immunosuppression. Children and younger adults accounted for most cases, hospitalizations and deaths. A reverse transcriptase-polymerase chain reaction assay was superior to antigen-based rapid tests for diagnosis. All 2009 H1N1 pandemic influenza strains were susceptible to 1 or more neuraminidase inhibitors. Monovalent, unadjuvanted 2009 H1N1 vaccines were licensed in the United States in September 2009 and initially targeted to younger individuals, pregnant women, caretakers of infants and healthcare providers. The 2009 H1N1 pandemic highlights the need for modernization of influenza vaccines, improved diagnostics and more rigorous evaluation of mitigation strategies.
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A08 01  1  ENG  @1 2009 H1N1 Influenza: A Twenty-First Century Pandemic With Roots in the Early Twentieth Century
A09 01  1  ENG  @1 Symposium: Emerging Pathogens and Knowledge in Infectious Diseases
A11 01  1    @1 FARLEY (Monica M.)
A12 01  1    @1 GREENFIELD (Ronald A.) @9 limin.
A12 02  1    @1 BRONZE (Michael S.) @9 limin.
A14 01      @1 Department of Medicine, Division of Infectious Diseases, Emory University School of Medicine and the Atlanta VA Medical Center @2 Atlanta, Georgia @3 USA @Z 1 aut.
A15 01      @1 Infectious Diseases Section, Department of Medicine, University of Oklahoma Health Sciences Center @2 Oklahoma City, Oklahoma @3 USA @Z 1 aut. @Z 2 aut.
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C01 01    ENG  @0 A swine-origin H1N1 triple-reassortant influenza A virus found to be a distant relative of the 1918 "Spanish flu" virus emerged in April 2009 to give rise to the first influenza pandemic of the 21st century. Although disease was generally mild and similar to seasonal influenza, severe manifestations including respiratory failure were noted in some, particularly those with underlying conditions such as asthma, pregnancy and immunosuppression. Children and younger adults accounted for most cases, hospitalizations and deaths. A reverse transcriptase-polymerase chain reaction assay was superior to antigen-based rapid tests for diagnosis. All 2009 H1N1 pandemic influenza strains were susceptible to 1 or more neuraminidase inhibitors. Monovalent, unadjuvanted 2009 H1N1 vaccines were licensed in the United States in September 2009 and initially targeted to younger individuals, pregnant women, caretakers of infants and healthcare providers. The 2009 H1N1 pandemic highlights the need for modernization of influenza vaccines, improved diagnostics and more rigorous evaluation of mitigation strategies.
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C03 01  X  SPA  @0 2009 @5 02
C03 02  X  FRE  @0 Santé publique @5 03
C03 02  X  ENG  @0 Public health @5 03
C03 02  X  SPA  @0 Salud pública @5 03
C03 03  X  FRE  @0 Grippe A @5 05
C03 03  X  ENG  @0 Influenza A @5 05
C03 03  X  SPA  @0 Gripe A @5 05
C03 04  X  FRE  @0 Monde @2 NG @5 06
C03 04  X  ENG  @0 World @2 NG @5 06
C03 04  X  SPA  @0 Mundo @2 NG @5 06
C03 05  X  FRE  @0 Racine @5 08
C03 05  X  ENG  @0 Root @5 08
C03 05  X  SPA  @0 Raíz @5 08
C03 06  X  FRE  @0 Précoce @5 09
C03 06  X  ENG  @0 Early @5 09
C03 06  X  SPA  @0 Precoz @5 09
C03 07  X  FRE  @0 Porcin @5 11
C03 07  X  ENG  @0 Swine @5 11
C03 07  X  SPA  @0 Porcino @5 11
C03 08  X  FRE  @0 Animal @5 12
C03 08  X  ENG  @0 Animal @5 12
C03 08  X  SPA  @0 Animal @5 12
C03 09  X  FRE  @0 Hémagglutinine @5 17
C03 09  X  ENG  @0 Hemagglutinin @5 17
C03 09  X  SPA  @0 Hemoaglutinina @5 17
C03 10  X  FRE  @0 Médecine @5 18
C03 10  X  ENG  @0 Medicine @5 18
C03 10  X  SPA  @0 Medicina @5 18
C03 11  X  FRE  @0 Pandémie @4 INC @5 86
C03 12  X  FRE  @0 Grippe H1N1 @4 CD @5 96
C03 12  X  ENG  @0 H1N1 influenza @4 CD @5 96
C03 12  X  SPA  @0 Gripe H1N1 @4 CD @5 96
C07 01  X  FRE  @0 Virose
C07 01  X  ENG  @0 Viral disease
C07 01  X  SPA  @0 Virosis
C07 02  X  FRE  @0 Infection
C07 02  X  ENG  @0 Infection
C07 02  X  SPA  @0 Infección
C07 03  X  FRE  @0 Artiodactyla @2 NS
C07 03  X  ENG  @0 Artiodactyla @2 NS
C07 03  X  SPA  @0 Artiodactyla @2 NS
C07 04  X  FRE  @0 Ungulata @2 NS
C07 04  X  ENG  @0 Ungulata @2 NS
C07 04  X  SPA  @0 Ungulata @2 NS
C07 05  X  FRE  @0 Mammalia @2 NS
C07 05  X  ENG  @0 Mammalia @2 NS
C07 05  X  SPA  @0 Mammalia @2 NS
C07 06  X  FRE  @0 Vertebrata @2 NS
C07 06  X  ENG  @0 Vertebrata @2 NS
C07 06  X  SPA  @0 Vertebrata @2 NS
C07 07  X  FRE  @0 Pathologie de l'appareil respiratoire @5 37
C07 07  X  ENG  @0 Respiratory disease @5 37
C07 07  X  SPA  @0 Aparato respiratorio patología @5 37
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Pascal:10-0457455

Le document en format XML

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