Drug susceptibility of influenza A/H3N2 strains co-circulating during 2009 influenza pandemic: first report from Mumbai.
Identifieur interne : 000B87 ( Main/Exploration ); précédent : 000B86; suivant : 000B88Drug susceptibility of influenza A/H3N2 strains co-circulating during 2009 influenza pandemic: first report from Mumbai.
Auteurs : Devanshi J. Gohil [Inde] ; Sweta T. Kothari [Inde] ; Pramod S. Shinde [Inde] ; Anand S. Chintakrindi [Inde] ; Rhuta Meharunkar [Inde] ; Rajas V. Warke [Inde] ; Meena A. Kanyalkar [Inde] ; Abhay S. Chowdhary [Inde] ; Ranjana A. Deshmukh [Inde]Source :
- Infection, genetics and evolution : journal of molecular epidemiology and evolutionary genetics in infectious diseases [ 1567-7257 ] ; 2015.
Descripteurs français
- KwdFr :
- Amantadine (pharmacologie), Animaux, Antiviraux (pharmacologie), Cellules rénales canines Madin-Darby, Chiens, Grippe humaine (virologie), Humains, Inde, Mutation, Oséltamivir (analogues et dérivés), Oséltamivir (pharmacologie), Pandémies, Partie nasale du pharynx (virologie), Phylogénie, Protéines de la matrice virale (génétique), Résistance virale aux médicaments (), Sialidase (métabolisme), Sous-type H3N2 du virus de la grippe A (), Sous-type H3N2 du virus de la grippe A (génétique).
- MESH :
- analogues et dérivés : Oséltamivir.
- génétique : Protéines de la matrice virale, Sous-type H3N2 du virus de la grippe A.
- métabolisme : Sialidase.
- pharmacologie : Amantadine, Antiviraux, Oséltamivir.
- virologie : Grippe humaine, Partie nasale du pharynx.
- Animaux, Cellules rénales canines Madin-Darby, Chiens, Humains, Inde, Mutation, Pandémies, Phylogénie, Résistance virale aux médicaments, Sous-type H3N2 du virus de la grippe A.
English descriptors
- KwdEn :
- Amantadine (pharmacology), Animals, Antiviral Agents (pharmacology), Dogs, Drug Resistance, Viral (drug effects), Humans, India, Influenza A Virus, H3N2 Subtype (drug effects), Influenza A Virus, H3N2 Subtype (genetics), Influenza, Human (virology), Madin Darby Canine Kidney Cells, Mutation, Nasopharynx (virology), Neuraminidase (metabolism), Oseltamivir (analogs & derivatives), Oseltamivir (pharmacology), Pandemics, Phylogeny, Viral Matrix Proteins (genetics).
- MESH :
- chemical , analogs & derivatives : Oseltamivir.
- chemical , genetics : Viral Matrix Proteins.
- chemical , metabolism : Neuraminidase.
- chemical , pharmacology : Amantadine, Antiviral Agents, Oseltamivir.
- drug effects : Drug Resistance, Viral, Influenza A Virus, H3N2 Subtype.
- genetics : Influenza A Virus, H3N2 Subtype.
- virology : Influenza, Human, Nasopharynx.
- Animals, Dogs, Humans, India, Madin Darby Canine Kidney Cells, Mutation, Pandemics, Phylogeny.
Abstract
From its first instance in 1977, resistance to amantadine, a matrix (M2) inhibitor has been increasing among influenza A/H3N2, thus propelling the use of oseltamivir, a neuraminidase (NA) inhibitor as a next line drug. Information on drug susceptibility to amantadine and neuraminidase inhibitors for influenza A/H3N2 viruses in India is limited with no published data from Mumbai. This study aimed at examining the sensitivity to M2 and NA inhibitors of influenza A/H3N2 strains isolated from 2009 to 2011 in Mumbai.
DOI: 10.1016/j.meegid.2014.11.005
PubMed: 25461259
Affiliations:
Links toward previous steps (curation, corpus...)
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Le document en format XML
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<term>Animals</term>
<term>Antiviral Agents (pharmacology)</term>
<term>Dogs</term>
<term>Drug Resistance, Viral (drug effects)</term>
<term>Humans</term>
<term>India</term>
<term>Influenza A Virus, H3N2 Subtype (drug effects)</term>
<term>Influenza A Virus, H3N2 Subtype (genetics)</term>
<term>Influenza, Human (virology)</term>
<term>Madin Darby Canine Kidney Cells</term>
<term>Mutation</term>
<term>Nasopharynx (virology)</term>
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<term>Oseltamivir (analogs & derivatives)</term>
<term>Oseltamivir (pharmacology)</term>
<term>Pandemics</term>
<term>Phylogeny</term>
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<term>Antiviraux (pharmacologie)</term>
<term>Cellules rénales canines Madin-Darby</term>
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<term>Grippe humaine (virologie)</term>
<term>Humains</term>
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<front><div type="abstract" xml:lang="en">From its first instance in 1977, resistance to amantadine, a matrix (M2) inhibitor has been increasing among influenza A/H3N2, thus propelling the use of oseltamivir, a neuraminidase (NA) inhibitor as a next line drug. Information on drug susceptibility to amantadine and neuraminidase inhibitors for influenza A/H3N2 viruses in India is limited with no published data from Mumbai. This study aimed at examining the sensitivity to M2 and NA inhibitors of influenza A/H3N2 strains isolated from 2009 to 2011 in Mumbai.</div>
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<name sortKey="Chintakrindi, Anand S" sort="Chintakrindi, Anand S" uniqKey="Chintakrindi A" first="Anand S" last="Chintakrindi">Anand S. Chintakrindi</name>
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