Bradykinesia, Muscle Weakness and Reduced Muscle Power in Parkinson's Disease
Identifieur interne : 000F63 ( PascalFrancis/Checkpoint ); précédent : 000F62; suivant : 000F64Bradykinesia, Muscle Weakness and Reduced Muscle Power in Parkinson's Disease
Auteurs : Natalie E. Allen [Australie] ; Colleen G. Canning [Australie] ; Catherine Sherrington [Australie] ; Victor S. C. Fung [Australie]Source :
- Movement disorders [ 0885-3185 ] ; 2009.
Descripteurs français
- Pascal (Inist)
English descriptors
- KwdEn :
Abstract
Muscle power (force velocity) could clarify the relationship between weakness and bradykinesia in Parkinson's disease (PD). The aims of this study were to determine if patients with PD were weaker and/or less powerful in their leg extensor muscles than a neurologically normal control group and to determine the relative contributions of force and movement velocity/bradykinesia to muscle power in PD. Forty patients with PD and 40 controls were assessed. Strength in Newtons (N) was measured as the heaviest load the participant could lift. Power in Watts (W) was measured by having the participant perform lifts as fast as possible. The PD group were 172 N weaker (95% CI 28-315) and 124 W less powerful at peak power (95% CI 32-216) than controls. However, velocity at maximal power was only reduced compared with controls when lifting light to medium loads. When lifting heavy loads bradykinesia was no longer apparent in the PD group. These results suggest that reduced muscle power in PD at lighter loads arises from weakness and bradykinesia combined, but at heavier loads arises only from weakness. The absence of bradykinesia in the PD group when lifting heavy loads warrants further investigation.
Affiliations:
Links toward previous steps (curation, corpus...)
Links to Exploration step
Pascal:09-0349984Le document en format XML
<record><TEI><teiHeader><fileDesc><titleStmt><title xml:lang="en" level="a">Bradykinesia, Muscle Weakness and Reduced Muscle Power in Parkinson's Disease</title><author><name sortKey="Allen, Natalie E" sort="Allen, Natalie E" uniqKey="Allen N" first="Natalie E." last="Allen">Natalie E. Allen</name><affiliation wicri:level="3"><inist:fA14 i1="01"><s1>Neurological Rehabilitation Research Group, Faculty of Health Sciences, The University of Sydney</s1><s2>Sydney</s2><s3>AUS</s3><sZ>1 aut.</sZ><sZ>2 aut.</sZ></inist:fA14><country>Australie</country><placeName><settlement type="city">Sydney</settlement></placeName></affiliation></author><author><name sortKey="Canning, Colleen G" sort="Canning, Colleen G" uniqKey="Canning C" first="Colleen G." last="Canning">Colleen G. Canning</name><affiliation wicri:level="3"><inist:fA14 i1="01"><s1>Neurological Rehabilitation Research Group, Faculty of Health Sciences, The University of Sydney</s1><s2>Sydney</s2><s3>AUS</s3><sZ>1 aut.</sZ><sZ>2 aut.</sZ></inist:fA14><country>Australie</country><placeName><settlement type="city">Sydney</settlement></placeName></affiliation></author><author><name sortKey="Sherrington, Catherine" sort="Sherrington, Catherine" uniqKey="Sherrington C" first="Catherine" last="Sherrington">Catherine Sherrington</name><affiliation wicri:level="3"><inist:fA14 i1="02"><s1>The George Institute for International Health, The University of Sydney</s1><s2>Sydney</s2><s3>AUS</s3><sZ>3 aut.</sZ></inist:fA14><country>Australie</country><placeName><settlement type="city">Sydney</settlement></placeName></affiliation></author><author><name sortKey="Fung, Victor S C" sort="Fung, Victor S C" uniqKey="Fung V" first="Victor S. C." last="Fung">Victor S. C. Fung</name><affiliation wicri:level="3"><inist:fA14 i1="03"><s1>Movement Disorder Unit, Department of Neurology, Westmead Hospital</s1><s2>Sydney</s2><s3>AUS</s3><sZ>4 aut.</sZ></inist:fA14><country>Australie</country><placeName><settlement type="city">Sydney</settlement></placeName></affiliation></author></titleStmt><publicationStmt><idno type="wicri:source">INIST</idno><idno type="inist">09-0349984</idno><date when="2009">2009</date><idno type="stanalyst">PASCAL 09-0349984 INIST</idno><idno type="RBID">Pascal:09-0349984</idno><idno type="wicri:Area/PascalFrancis/Corpus">000E20</idno><idno type="wicri:Area/PascalFrancis/Curation">001E99</idno><idno type="wicri:Area/PascalFrancis/Checkpoint">000F63</idno></publicationStmt><sourceDesc><biblStruct><analytic><title xml:lang="en" level="a">Bradykinesia, Muscle Weakness and Reduced Muscle Power in Parkinson's Disease</title><author><name sortKey="Allen, Natalie E" sort="Allen, Natalie E" uniqKey="Allen N" first="Natalie E." last="Allen">Natalie E. Allen</name><affiliation wicri:level="3"><inist:fA14 i1="01"><s1>Neurological Rehabilitation Research Group, Faculty of Health Sciences, The University of Sydney</s1><s2>Sydney</s2><s3>AUS</s3><sZ>1 aut.</sZ><sZ>2 aut.</sZ></inist:fA14><country>Australie</country><placeName><settlement type="city">Sydney</settlement></placeName></affiliation></author><author><name sortKey="Canning, Colleen G" sort="Canning, Colleen G" uniqKey="Canning C" first="Colleen G." last="Canning">Colleen G. Canning</name><affiliation wicri:level="3"><inist:fA14 i1="01"><s1>Neurological Rehabilitation Research Group, Faculty of Health Sciences, The University of Sydney</s1><s2>Sydney</s2><s3>AUS</s3><sZ>1 aut.</sZ><sZ>2 aut.</sZ></inist:fA14><country>Australie</country><placeName><settlement type="city">Sydney</settlement></placeName></affiliation></author><author><name sortKey="Sherrington, Catherine" sort="Sherrington, Catherine" uniqKey="Sherrington C" first="Catherine" last="Sherrington">Catherine Sherrington</name><affiliation wicri:level="3"><inist:fA14 i1="02"><s1>The George Institute for International Health, The University of Sydney</s1><s2>Sydney</s2><s3>AUS</s3><sZ>3 aut.</sZ></inist:fA14><country>Australie</country><placeName><settlement type="city">Sydney</settlement></placeName></affiliation></author><author><name sortKey="Fung, Victor S C" sort="Fung, Victor S C" uniqKey="Fung V" first="Victor S. C." last="Fung">Victor S. C. Fung</name><affiliation wicri:level="3"><inist:fA14 i1="03"><s1>Movement Disorder Unit, Department of Neurology, Westmead Hospital</s1><s2>Sydney</s2><s3>AUS</s3><sZ>4 aut.</sZ></inist:fA14><country>Australie</country><placeName><settlement type="city">Sydney</settlement></placeName></affiliation></author></analytic><series><title level="j" type="main">Movement disorders</title><title level="j" type="abbreviated">Mov. disord.</title><idno type="ISSN">0885-3185</idno><imprint><date when="2009">2009</date></imprint></series></biblStruct></sourceDesc><seriesStmt><title level="j" type="main">Movement disorders</title><title level="j" type="abbreviated">Mov. disord.</title><idno type="ISSN">0885-3185</idno></seriesStmt></fileDesc><profileDesc><textClass><keywords scheme="KwdEn" xml:lang="en"><term>Nervous system diseases</term><term>Parkinson disease</term></keywords><keywords scheme="Pascal" xml:lang="fr"><term>Maladie de Parkinson</term><term>Pathologie du système nerveux</term></keywords></textClass></profileDesc></teiHeader><front><div type="abstract" xml:lang="en">Muscle power (force velocity) could clarify the relationship between weakness and bradykinesia in Parkinson's disease (PD). The aims of this study were to determine if patients with PD were weaker and/or less powerful in their leg extensor muscles than a neurologically normal control group and to determine the relative contributions of force and movement velocity/bradykinesia to muscle power in PD. Forty patients with PD and 40 controls were assessed. Strength in Newtons (N) was measured as the heaviest load the participant could lift. Power in Watts (W) was measured by having the participant perform lifts as fast as possible. The PD group were 172 N weaker (95% CI 28-315) and 124 W less powerful at peak power (95% CI 32-216) than controls. However, velocity at maximal power was only reduced compared with controls when lifting light to medium loads. When lifting heavy loads bradykinesia was no longer apparent in the PD group. These results suggest that reduced muscle power in PD at lighter loads arises from weakness and bradykinesia combined, but at heavier loads arises only from weakness. The absence of bradykinesia in the PD group when lifting heavy loads warrants further investigation.</div></front></TEI><inist><standard h6="B"><pA><fA01 i1="01" i2="1"><s0>0885-3185</s0></fA01><fA03 i2="1"><s0>Mov. disord.</s0></fA03><fA05><s2>24</s2></fA05><fA06><s2>9</s2></fA06><fA08 i1="01" i2="1" l="ENG"><s1>Bradykinesia, Muscle Weakness and Reduced Muscle Power in Parkinson's Disease</s1></fA08><fA11 i1="01" i2="1"><s1>ALLEN (Natalie E.)</s1></fA11><fA11 i1="02" i2="1"><s1>CANNING (Colleen G.)</s1></fA11><fA11 i1="03" i2="1"><s1>SHERRINGTON (Catherine)</s1></fA11><fA11 i1="04" i2="1"><s1>FUNG (Victor S. C.)</s1></fA11><fA14 i1="01"><s1>Neurological Rehabilitation Research Group, Faculty of Health Sciences, The University of Sydney</s1><s2>Sydney</s2><s3>AUS</s3><sZ>1 aut.</sZ><sZ>2 aut.</sZ></fA14><fA14 i1="02"><s1>The George Institute for International Health, The University of Sydney</s1><s2>Sydney</s2><s3>AUS</s3><sZ>3 aut.</sZ></fA14><fA14 i1="03"><s1>Movement Disorder Unit, Department of Neurology, Westmead Hospital</s1><s2>Sydney</s2><s3>AUS</s3><sZ>4 aut.</sZ></fA14><fA20><s1>1344-1351</s1></fA20><fA21><s1>2009</s1></fA21><fA23 i1="01"><s0>ENG</s0></fA23><fA43 i1="01"><s1>INIST</s1><s2>20953</s2><s5>354000170902500130</s5></fA43><fA44><s0>0000</s0><s1>© 2009 INIST-CNRS. All rights reserved.</s1></fA44><fA45><s0>32 ref.</s0></fA45><fA47 i1="01" i2="1"><s0>09-0349984</s0></fA47><fA60><s1>P</s1></fA60><fA61><s0>A</s0></fA61><fA64 i1="01" i2="1"><s0>Movement disorders</s0></fA64><fA66 i1="01"><s0>USA</s0></fA66><fC01 i1="01" l="ENG"><s0>Muscle power (force velocity) could clarify the relationship between weakness and bradykinesia in Parkinson's disease (PD). The aims of this study were to determine if patients with PD were weaker and/or less powerful in their leg extensor muscles than a neurologically normal control group and to determine the relative contributions of force and movement velocity/bradykinesia to muscle power in PD. Forty patients with PD and 40 controls were assessed. Strength in Newtons (N) was measured as the heaviest load the participant could lift. Power in Watts (W) was measured by having the participant perform lifts as fast as possible. The PD group were 172 N weaker (95% CI 28-315) and 124 W less powerful at peak power (95% CI 32-216) than controls. However, velocity at maximal power was only reduced compared with controls when lifting light to medium loads. When lifting heavy loads bradykinesia was no longer apparent in the PD group. These results suggest that reduced muscle power in PD at lighter loads arises from weakness and bradykinesia combined, but at heavier loads arises only from weakness. The absence of bradykinesia in the PD group when lifting heavy loads warrants further investigation.</s0></fC01><fC02 i1="01" i2="X"><s0>002B17</s0></fC02><fC02 i1="02" i2="X"><s0>002B17G</s0></fC02><fC03 i1="01" i2="X" l="FRE"><s0>Maladie de Parkinson</s0><s2>NM</s2><s5>01</s5></fC03><fC03 i1="01" i2="X" l="ENG"><s0>Parkinson disease</s0><s2>NM</s2><s5>01</s5></fC03><fC03 i1="01" i2="X" l="SPA"><s0>Parkinson enfermedad</s0><s2>NM</s2><s5>01</s5></fC03><fC03 i1="02" i2="X" l="FRE"><s0>Pathologie du système nerveux</s0><s5>02</s5></fC03><fC03 i1="02" i2="X" l="ENG"><s0>Nervous system diseases</s0><s5>02</s5></fC03><fC03 i1="02" i2="X" l="SPA"><s0>Sistema nervioso patología</s0><s5>02</s5></fC03><fC07 i1="01" i2="X" l="FRE"><s0>Pathologie de l'encéphale</s0><s5>37</s5></fC07><fC07 i1="01" i2="X" l="ENG"><s0>Cerebral disorder</s0><s5>37</s5></fC07><fC07 i1="01" i2="X" l="SPA"><s0>Encéfalo patología</s0><s5>37</s5></fC07><fC07 i1="02" i2="X" l="FRE"><s0>Syndrome extrapyramidal</s0><s5>38</s5></fC07><fC07 i1="02" i2="X" l="ENG"><s0>Extrapyramidal syndrome</s0><s5>38</s5></fC07><fC07 i1="02" i2="X" l="SPA"><s0>Extrapiramidal síndrome</s0><s5>38</s5></fC07><fC07 i1="03" i2="X" l="FRE"><s0>Maladie dégénérative</s0><s5>39</s5></fC07><fC07 i1="03" i2="X" l="ENG"><s0>Degenerative disease</s0><s5>39</s5></fC07><fC07 i1="03" i2="X" l="SPA"><s0>Enfermedad degenerativa</s0><s5>39</s5></fC07><fC07 i1="04" i2="X" l="FRE"><s0>Pathologie du système nerveux central</s0><s5>40</s5></fC07><fC07 i1="04" i2="X" l="ENG"><s0>Central nervous system disease</s0><s5>40</s5></fC07><fC07 i1="04" i2="X" l="SPA"><s0>Sistema nervosio central patología</s0><s5>40</s5></fC07><fN21><s1>257</s1></fN21><fN44 i1="01"><s1>OTO</s1></fN44><fN82><s1>OTO</s1></fN82></pA></standard></inist><affiliations><list><country><li>Australie</li></country><settlement><li>Sydney</li></settlement></list><tree><country name="Australie"><noRegion><name sortKey="Allen, Natalie E" sort="Allen, Natalie E" uniqKey="Allen N" first="Natalie E." last="Allen">Natalie E. Allen</name></noRegion><name sortKey="Canning, Colleen G" sort="Canning, Colleen G" uniqKey="Canning C" first="Colleen G." last="Canning">Colleen G. Canning</name><name sortKey="Fung, Victor S C" sort="Fung, Victor S C" uniqKey="Fung V" first="Victor S. C." last="Fung">Victor S. C. Fung</name><name sortKey="Sherrington, Catherine" sort="Sherrington, Catherine" uniqKey="Sherrington C" first="Catherine" last="Sherrington">Catherine Sherrington</name></country></tree></affiliations></record>Pour manipuler ce document sous Unix (Dilib)
EXPLOR_STEP=$WICRI_ROOT/Wicri/Santé/explor/MovDisordV3/Data/PascalFrancis/Checkpoint
HfdSelect -h $EXPLOR_STEP/biblio.hfd -nk 000F63 | SxmlIndent | more
Ou
HfdSelect -h $EXPLOR_AREA/Data/PascalFrancis/Checkpoint/biblio.hfd -nk 000F63 | SxmlIndent | more
Pour mettre un lien sur cette page dans le réseau Wicri
{{Explor lien
|wiki= Wicri/Santé
|area= MovDisordV3
|flux= PascalFrancis
|étape= Checkpoint
|type= RBID
|clé= Pascal:09-0349984
|texte= Bradykinesia, Muscle Weakness and Reduced Muscle Power in Parkinson's Disease
}}
| This area was generated with Dilib version V0.6.23. |  |