MovDisordV3, Ncbi, Curation, bibRecord, 002B93

Longitudinal Tracking of Gait and Balance Impairments in Cerebellar Disease

Identifieur interne : 002B93 ( Ncbi/Curation ); précédent : 002B92; suivant : 002B94

Longitudinal Tracking of Gait and Balance Impairments in Cerebellar Disease

Auteurs : Susanne M. Morton [États-Unis] ; Ya-Weng Tseng [États-Unis] ; Kathleen M. Zackowski [États-Unis] ; Jaclyn R. Daline [États-Unis] ; Amy J. Bastian [États-Unis]

Source :

Movement disorders : official journal of the Movement Disorder Society [ 0885-3185 ] ; 2010.

RBID : PMC:2939173

English descriptors

KwdEn :
- Analysis of Variance, Cerebellar Diseases (physiopathology), Cerebellum (injuries), Cerebellum (physiopathology), Gait, Gait Ataxia (physiopathology), Humans, Neurologic Examination, Postural Balance, Severity of Illness Index, Statistics, Nonparametric.
MESH :
- injuries : Cerebellum.
- physiopathology : Cerebellar Diseases, Cerebellum, Gait Ataxia.
- Analysis of Variance, Gait, Humans, Neurologic Examination, Postural Balance, Severity of Illness Index, Statistics, Nonparametric.

Abstract

Cerebellar damage typically results in ataxia and can be caused by stroke, tumor or one of many forms of degenerative disease. Since few pharmacological options are available, most treatments rely heavily on rehabilitation therapy. Little data exist on methods for tracking the progression of ataxia, which is critical for assessing the efficacy of current and newly developing treatments. Here, we tracked the severity of ataxia, with a particular emphasis on gait and balance dysfunction, in a group of individuals with cerebellar damage using the International Cooperative Ataxia Rating Scale (ICARS) and several instrumented laboratory measures of gait and balance impairments over one year. We found that the ICARS was able to distinguish between subjects with static lesions and those with degenerative disorders, was sensitive to increases in ataxia severity occurring over one year, and correlated well with specific instrumented measures of gait in persons with cerebellar degeneration. These results suggest the ICARS is a valuable tool for clinicians and investigators to document and track long-term changes in gait and balance performance in individuals with cerebellar degenerative disorders.

Url:

http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2939173

DOI: 10.1002/mds.23169
PubMed: 20544808
PubMed Central: 2939173

Links toward previous steps (curation, corpus...)

to stream Pmc, to step Corpus: Pour aller vers cette notice dans l'étape Curation :000091
to stream Pmc, to step Curation: Pour aller vers cette notice dans l'étape Curation :000091
to stream Pmc, to step Checkpoint: Pour aller vers cette notice dans l'étape Curation :000332
to stream PubMed, to step Corpus: Pour aller vers cette notice dans l'étape Curation :001809
to stream PubMed, to step Curation: Pour aller vers cette notice dans l'étape Curation :001809
to stream PubMed, to step Checkpoint: Pour aller vers cette notice dans l'étape Curation :001791
to stream Ncbi, to step Merge: Pour aller vers cette notice dans l'étape Curation :002B93

Links to Exploration step

PMC:2939173

Le document en format XML

<record><TEI><teiHeader><fileDesc><titleStmt><title xml:lang="en">Longitudinal Tracking of Gait and Balance Impairments in Cerebellar Disease</title>
<author><name sortKey="Morton, Susanne M" sort="Morton, Susanne M" uniqKey="Morton S" first="Susanne M." last="Morton">Susanne M. Morton</name>
<affiliation wicri:level="2"><nlm:aff id="A1"> Graduate Program in Physical Therapy & Rehabilitation Science, University of Iowa Carver College of Medicine, Iowa City, IA 52242</nlm:aff>
<country xml:lang="fr">États-Unis</country>
<placeName><region type="state">Iowa</region>
</placeName>
<wicri:cityArea> Graduate Program in Physical Therapy & Rehabilitation Science, University of Iowa Carver College of Medicine, Iowa City</wicri:cityArea>
</affiliation>
</author>
<author><name sortKey="Tseng, Ya Weng" sort="Tseng, Ya Weng" uniqKey="Tseng Y" first="Ya-Weng" last="Tseng">Ya-Weng Tseng</name>
<affiliation wicri:level="2"><nlm:aff id="A2"> Department of Physical Therapy, Temple University, Philadelphia, PA 19140</nlm:aff>
<country xml:lang="fr">États-Unis</country>
<placeName><region type="state">Pennsylvanie</region>
</placeName>
<wicri:cityArea> Department of Physical Therapy, Temple University, Philadelphia</wicri:cityArea>
</affiliation>
</author>
<author><name sortKey="Zackowski, Kathleen M" sort="Zackowski, Kathleen M" uniqKey="Zackowski K" first="Kathleen M." last="Zackowski">Kathleen M. Zackowski</name>
<affiliation wicri:level="2"><nlm:aff id="A3"> Kennedy Krieger Institute, Baltimore, MD 21205</nlm:aff>
<country xml:lang="fr">États-Unis</country>
<placeName><region type="state">Maryland</region>
</placeName>
<wicri:cityArea> Kennedy Krieger Institute, Baltimore</wicri:cityArea>
</affiliation>
<affiliation wicri:level="2"><nlm:aff id="A4"> Department of Neurology, Johns Hopkins University School of Medicine, Baltimore, MD 21205</nlm:aff>
<country xml:lang="fr">États-Unis</country>
<placeName><region type="state">Maryland</region>
</placeName>
<wicri:cityArea> Department of Neurology, Johns Hopkins University School of Medicine, Baltimore</wicri:cityArea>
</affiliation>
<affiliation wicri:level="2"><nlm:aff id="A5"> Department of Physical Medicine & Rehabilitation, Johns Hopkins University School of Medicine, Baltimore, MD 21205</nlm:aff>
<country xml:lang="fr">États-Unis</country>
<placeName><region type="state">Maryland</region>
</placeName>
<wicri:cityArea> Department of Physical Medicine & Rehabilitation, Johns Hopkins University School of Medicine, Baltimore</wicri:cityArea>
</affiliation>
</author>
<author><name sortKey="Daline, Jaclyn R" sort="Daline, Jaclyn R" uniqKey="Daline J" first="Jaclyn R." last="Daline">Jaclyn R. Daline</name>
<affiliation wicri:level="2"><nlm:aff id="A6"> Program in Physical Therapy, Washington University School of Medicine, St. Louis, MO 63108</nlm:aff>
<country xml:lang="fr">États-Unis</country>
<placeName><region type="state">Missouri (État)</region>
</placeName>
<wicri:cityArea> Program in Physical Therapy, Washington University School of Medicine, St. Louis</wicri:cityArea>
</affiliation>
</author>
<author><name sortKey="Bastian, Amy J" sort="Bastian, Amy J" uniqKey="Bastian A" first="Amy J." last="Bastian">Amy J. Bastian</name>
<affiliation wicri:level="2"><nlm:aff id="A3"> Kennedy Krieger Institute, Baltimore, MD 21205</nlm:aff>
<country xml:lang="fr">États-Unis</country>
<placeName><region type="state">Maryland</region>
</placeName>
<wicri:cityArea> Kennedy Krieger Institute, Baltimore</wicri:cityArea>
</affiliation>
<affiliation wicri:level="2"><nlm:aff id="A4"> Department of Neurology, Johns Hopkins University School of Medicine, Baltimore, MD 21205</nlm:aff>
<country xml:lang="fr">États-Unis</country>
<placeName><region type="state">Maryland</region>
</placeName>
<wicri:cityArea> Department of Neurology, Johns Hopkins University School of Medicine, Baltimore</wicri:cityArea>
</affiliation>
<affiliation wicri:level="2"><nlm:aff id="A5"> Department of Physical Medicine & Rehabilitation, Johns Hopkins University School of Medicine, Baltimore, MD 21205</nlm:aff>
<country xml:lang="fr">États-Unis</country>
<placeName><region type="state">Maryland</region>
</placeName>
<wicri:cityArea> Department of Physical Medicine & Rehabilitation, Johns Hopkins University School of Medicine, Baltimore</wicri:cityArea>
</affiliation>
</author>
</titleStmt>
<publicationStmt><idno type="wicri:source">PMC</idno>
<idno type="pmid">20544808</idno>
<idno type="pmc">2939173</idno>
<idno type="url">http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2939173</idno>
<idno type="RBID">PMC:2939173</idno>
<idno type="doi">10.1002/mds.23169</idno>
<date when="2010">2010</date>
<idno type="wicri:Area/Pmc/Corpus">000091</idno>
<idno type="wicri:Area/Pmc/Curation">000091</idno>
<idno type="wicri:Area/Pmc/Checkpoint">000332</idno>
<idno type="wicri:source">PubMed</idno>
<idno type="wicri:Area/PubMed/Corpus">001809</idno>
<idno type="wicri:Area/PubMed/Curation">001809</idno>
<idno type="wicri:Area/PubMed/Checkpoint">001791</idno>
<idno type="wicri:Area/Ncbi/Merge">002B93</idno>
<idno type="wicri:Area/Ncbi/Curation">002B93</idno>
</publicationStmt>
<sourceDesc><biblStruct><analytic><title xml:lang="en" level="a" type="main">Longitudinal Tracking of Gait and Balance Impairments in Cerebellar Disease</title>
<author><name sortKey="Morton, Susanne M" sort="Morton, Susanne M" uniqKey="Morton S" first="Susanne M." last="Morton">Susanne M. Morton</name>
<affiliation wicri:level="2"><nlm:aff id="A1"> Graduate Program in Physical Therapy & Rehabilitation Science, University of Iowa Carver College of Medicine, Iowa City, IA 52242</nlm:aff>
<country xml:lang="fr">États-Unis</country>
<placeName><region type="state">Iowa</region>
</placeName>
<wicri:cityArea> Graduate Program in Physical Therapy & Rehabilitation Science, University of Iowa Carver College of Medicine, Iowa City</wicri:cityArea>
</affiliation>
</author>
<author><name sortKey="Tseng, Ya Weng" sort="Tseng, Ya Weng" uniqKey="Tseng Y" first="Ya-Weng" last="Tseng">Ya-Weng Tseng</name>
<affiliation wicri:level="2"><nlm:aff id="A2"> Department of Physical Therapy, Temple University, Philadelphia, PA 19140</nlm:aff>
<country xml:lang="fr">États-Unis</country>
<placeName><region type="state">Pennsylvanie</region>
</placeName>
<wicri:cityArea> Department of Physical Therapy, Temple University, Philadelphia</wicri:cityArea>
</affiliation>
</author>
<author><name sortKey="Zackowski, Kathleen M" sort="Zackowski, Kathleen M" uniqKey="Zackowski K" first="Kathleen M." last="Zackowski">Kathleen M. Zackowski</name>
<affiliation wicri:level="2"><nlm:aff id="A3"> Kennedy Krieger Institute, Baltimore, MD 21205</nlm:aff>
<country xml:lang="fr">États-Unis</country>
<placeName><region type="state">Maryland</region>
</placeName>
<wicri:cityArea> Kennedy Krieger Institute, Baltimore</wicri:cityArea>
</affiliation>
<affiliation wicri:level="2"><nlm:aff id="A4"> Department of Neurology, Johns Hopkins University School of Medicine, Baltimore, MD 21205</nlm:aff>
<country xml:lang="fr">États-Unis</country>
<placeName><region type="state">Maryland</region>
</placeName>
<wicri:cityArea> Department of Neurology, Johns Hopkins University School of Medicine, Baltimore</wicri:cityArea>
</affiliation>
<affiliation wicri:level="2"><nlm:aff id="A5"> Department of Physical Medicine & Rehabilitation, Johns Hopkins University School of Medicine, Baltimore, MD 21205</nlm:aff>
<country xml:lang="fr">États-Unis</country>
<placeName><region type="state">Maryland</region>
</placeName>
<wicri:cityArea> Department of Physical Medicine & Rehabilitation, Johns Hopkins University School of Medicine, Baltimore</wicri:cityArea>
</affiliation>
</author>
<author><name sortKey="Daline, Jaclyn R" sort="Daline, Jaclyn R" uniqKey="Daline J" first="Jaclyn R." last="Daline">Jaclyn R. Daline</name>
<affiliation wicri:level="2"><nlm:aff id="A6"> Program in Physical Therapy, Washington University School of Medicine, St. Louis, MO 63108</nlm:aff>
<country xml:lang="fr">États-Unis</country>
<placeName><region type="state">Missouri (État)</region>
</placeName>
<wicri:cityArea> Program in Physical Therapy, Washington University School of Medicine, St. Louis</wicri:cityArea>
</affiliation>
</author>
<author><name sortKey="Bastian, Amy J" sort="Bastian, Amy J" uniqKey="Bastian A" first="Amy J." last="Bastian">Amy J. Bastian</name>
<affiliation wicri:level="2"><nlm:aff id="A3"> Kennedy Krieger Institute, Baltimore, MD 21205</nlm:aff>
<country xml:lang="fr">États-Unis</country>
<placeName><region type="state">Maryland</region>
</placeName>
<wicri:cityArea> Kennedy Krieger Institute, Baltimore</wicri:cityArea>
</affiliation>
<affiliation wicri:level="2"><nlm:aff id="A4"> Department of Neurology, Johns Hopkins University School of Medicine, Baltimore, MD 21205</nlm:aff>
<country xml:lang="fr">États-Unis</country>
<placeName><region type="state">Maryland</region>
</placeName>
<wicri:cityArea> Department of Neurology, Johns Hopkins University School of Medicine, Baltimore</wicri:cityArea>
</affiliation>
<affiliation wicri:level="2"><nlm:aff id="A5"> Department of Physical Medicine & Rehabilitation, Johns Hopkins University School of Medicine, Baltimore, MD 21205</nlm:aff>
<country xml:lang="fr">États-Unis</country>
<placeName><region type="state">Maryland</region>
</placeName>
<wicri:cityArea> Department of Physical Medicine & Rehabilitation, Johns Hopkins University School of Medicine, Baltimore</wicri:cityArea>
</affiliation>
</author>
</analytic>
<series><title level="j">Movement disorders : official journal of the Movement Disorder Society</title>
<idno type="ISSN">0885-3185</idno>
<idno type="eISSN">1531-8257</idno>
<imprint><date when="2010">2010</date>
</imprint>
</series>
</biblStruct>
</sourceDesc>
</fileDesc>
<profileDesc><textClass><keywords scheme="KwdEn" xml:lang="en"><term>Analysis of Variance</term>
<term>Cerebellar Diseases (physiopathology)</term>
<term>Cerebellum (injuries)</term>
<term>Cerebellum (physiopathology)</term>
<term>Gait</term>
<term>Gait Ataxia (physiopathology)</term>
<term>Humans</term>
<term>Neurologic Examination</term>
<term>Postural Balance</term>
<term>Severity of Illness Index</term>
<term>Statistics, Nonparametric</term>
</keywords>
<keywords scheme="MESH" qualifier="injuries" xml:lang="en"><term>Cerebellum</term>
</keywords>
<keywords scheme="MESH" qualifier="physiopathology" xml:lang="en"><term>Cerebellar Diseases</term>
<term>Cerebellum</term>
<term>Gait Ataxia</term>
</keywords>
<keywords scheme="MESH" xml:lang="en"><term>Analysis of Variance</term>
<term>Gait</term>
<term>Humans</term>
<term>Neurologic Examination</term>
<term>Postural Balance</term>
<term>Severity of Illness Index</term>
<term>Statistics, Nonparametric</term>
</keywords>
</textClass>
</profileDesc>
</teiHeader>
<front><div type="abstract" xml:lang="en"><p id="P1">Cerebellar damage typically results in ataxia and can be caused by stroke, tumor or one of many forms of degenerative disease. Since few pharmacological options are available, most treatments rely heavily on rehabilitation therapy. Little data exist on methods for tracking the progression of ataxia, which is critical for assessing the efficacy of current and newly developing treatments. Here, we tracked the severity of ataxia, with a particular emphasis on gait and balance dysfunction, in a group of individuals with cerebellar damage using the International Cooperative Ataxia Rating Scale (ICARS) and several instrumented laboratory measures of gait and balance impairments over one year. We found that the ICARS was able to distinguish between subjects with static lesions and those with degenerative disorders, was sensitive to increases in ataxia severity occurring over one year, and correlated well with specific instrumented measures of gait in persons with cerebellar degeneration. These results suggest the ICARS is a valuable tool for clinicians and investigators to document and track long-term changes in gait and balance performance in individuals with cerebellar degenerative disorders.</p>
</div>
</front>
</TEI>
</record>

Pour manipuler ce document sous Unix (Dilib)

EXPLOR_STEP=$WICRI_ROOT/Wicri/Santé/explor/MovDisordV3/Data/Ncbi/Curation

HfdSelect -h $EXPLOR_STEP/biblio.hfd -nk 002B93 | SxmlIndent | more

HfdSelect -h $EXPLOR_AREA/Data/Ncbi/Curation/biblio.hfd -nk 002B93 | SxmlIndent | more

Pour mettre un lien sur cette page dans le réseau Wicri

{{Explor lien
   |wiki=    Wicri/Santé
   |area=    MovDisordV3
   |flux=    Ncbi
   |étape=   Curation
   |type=    RBID
   |clé=     PMC:2939173
   |texte=   Longitudinal Tracking of Gait and Balance Impairments in Cerebellar Disease
}}

Pour générer des pages wiki

HfdIndexSelect -h $EXPLOR_AREA/Data/Ncbi/Curation/RBID.i   -Sk "pubmed:20544808" \
       | HfdSelect -Kh $EXPLOR_AREA/Data/Ncbi/Curation/biblio.hfd   \
       | NlmPubMed2Wicri -a MovDisordV3

This area was generated with Dilib version V0.6.23.
Data generation: Sun Jul 3 12:29:32 2016. Site generation: Wed Feb 14 10:52:30 2024

	Movement Disorders (revue)
	Attention, ce site est en cours de développement ! Attention, site généré par des moyens informatiques à partir de corpus bruts. Les informations ne sont donc pas validées.

Movement Disorders (revue)

Longitudinal Tracking of Gait and Balance Impairments in Cerebellar Disease

Longitudinal Tracking of Gait and Balance Impairments in Cerebellar Disease

Source :

English descriptors

Abstract

Links toward previous steps (curation, corpus...)

Links to Exploration step

Le document en format XML

Pour manipuler ce document sous Unix (Dilib)

Pour mettre un lien sur cette page dans le réseau Wicri

Pour générer des pages wiki