MovDisordV3, Main, Merge, bibRecord, 007605

Early detection of probable idiopathic Parkinson's disease : II. A prospective application of a diagnostic test battery

Identifieur interne : 007605 ( Main/Merge ); précédent : 007604; suivant : 007606

Early detection of probable idiopathic Parkinson's disease : II. A prospective application of a diagnostic test battery

Auteurs : E. B. Jr Montgomery [États-Unis] ; K. Lyons [États-Unis] ; W. C. Koller [États-Unis]

Source :

Movement disorders [ 0885-3185 ] ; 2000.

RBID : Pascal:00-0271640

Descripteurs français

Pascal (Inist)
- Parkinson maladie, Olfaction, Mouvement, Humeur, Evaluation performance, Dépistage, Précoce, Homme.
Wicri :
- topic : Homme.

English descriptors

KwdEn :
- Early, Human, Medical screening, Mood, Motion, Olfaction, Parkinson disease, Performance evaluation.

Abstract

We developed a battery of tests, incorporating motor function, olfaction, and mood, that distinguishes between early mild, probable idiopathic Parkinson's disease (iPD), and normal control subjects. Here, we determined the PD Battery's ability to prospectively identify which patients with symptoms and signs suggestive of, but not yet diagnostic of, iPD who would subsequently be diagnosed as having iPD. Of 212 enrolled patients, 194 have been followed for at least 1 year. Among these 194, 59 were diagnosed with iPD, 40 as neurologically normal, and the remaining 106 with other neurologic conditions such as essential tremor. The test battery was 92% specific and 68% sensitive for iPD. The area under the Receiver Operating Characteristics curve was 0.88 for predicting which participants would subsequently be diagnosed as having iPD or as being neurologically normal.

Links toward previous steps (curation, corpus...)

to stream PascalFrancis, to step Corpus: 002B97
to stream PascalFrancis, to step Curation: 000124
to stream PascalFrancis, to step Checkpoint: 002C13

Links to Exploration step

Pascal:00-0271640

Le document en format XML

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<author><name sortKey="Montgomery, E B Jr" sort="Montgomery, E B Jr" uniqKey="Montgomery E" first="E. B. Jr" last="Montgomery">E. B. Jr Montgomery</name>
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<author><name sortKey="Lyons, K" sort="Lyons, K" uniqKey="Lyons K" first="K." last="Lyons">K. Lyons</name>
<affiliation wicri:level="2"><inist:fA14 i1="02"><s1>National Parkinson Foundation, University of Miami Medical Center</s1>
<s2>Miami, Florida</s2>
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<country>États-Unis</country>
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<author><name sortKey="Koller, W C" sort="Koller, W C" uniqKey="Koller W" first="W. C." last="Koller">W. C. Koller</name>
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<sourceDesc><biblStruct><analytic><title xml:lang="en" level="a">Early detection of probable idiopathic Parkinson's disease : II. A prospective application of a diagnostic test battery</title>
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<author><name sortKey="Lyons, K" sort="Lyons, K" uniqKey="Lyons K" first="K." last="Lyons">K. Lyons</name>
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<series><title level="j" type="main">Movement disorders</title>
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<profileDesc><textClass><keywords scheme="KwdEn" xml:lang="en"><term>Early</term>
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<term>Mood</term>
<term>Motion</term>
<term>Olfaction</term>
<term>Parkinson disease</term>
<term>Performance evaluation</term>
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<keywords scheme="Pascal" xml:lang="fr"><term>Parkinson maladie</term>
<term>Olfaction</term>
<term>Mouvement</term>
<term>Humeur</term>
<term>Evaluation performance</term>
<term>Dépistage</term>
<term>Précoce</term>
<term>Homme</term>
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<front><div type="abstract" xml:lang="en">We developed a battery of tests, incorporating motor function, olfaction, and mood, that distinguishes between early mild, probable idiopathic Parkinson's disease (iPD), and normal control subjects. Here, we determined the PD Battery's ability to prospectively identify which patients with symptoms and signs suggestive of, but not yet diagnostic of, iPD who would subsequently be diagnosed as having iPD. Of 212 enrolled patients, 194 have been followed for at least 1 year. Among these 194, 59 were diagnosed with iPD, 40 as neurologically normal, and the remaining 106 with other neurologic conditions such as essential tremor. The test battery was 92% specific and 68% sensitive for iPD. The area under the Receiver Operating Characteristics curve was 0.88 for predicting which participants would subsequently be diagnosed as having iPD or as being neurologically normal.</div>
</front>
</TEI>
<affiliations><list><country><li>États-Unis</li>
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<tree><country name="États-Unis"><region name="Ohio"><name sortKey="Montgomery, E B Jr" sort="Montgomery, E B Jr" uniqKey="Montgomery E" first="E. B. Jr" last="Montgomery">E. B. Jr Montgomery</name>
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<name sortKey="Koller, W C" sort="Koller, W C" uniqKey="Koller W" first="W. C." last="Koller">W. C. Koller</name>
<name sortKey="Lyons, K" sort="Lyons, K" uniqKey="Lyons K" first="K." last="Lyons">K. Lyons</name>
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	Movement Disorders (revue)
	Attention, ce site est en cours de développement ! Attention, site généré par des moyens informatiques à partir de corpus bruts. Les informations ne sont donc pas validées.

Movement Disorders (revue)

Early detection of probable idiopathic Parkinson's disease : II. A prospective application of a diagnostic test battery

Early detection of probable idiopathic Parkinson's disease : II. A prospective application of a diagnostic test battery

Source :

Descripteurs français

English descriptors

Abstract

Links toward previous steps (curation, corpus...)

Links to Exploration step

Le document en format XML

Pour manipuler ce document sous Unix (Dilib)

Pour mettre un lien sur cette page dans le réseau Wicri