Movement Disorders (revue)

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Early detection of probable idiopathic Parkinson's disease : II. A prospective application of a diagnostic test battery

Identifieur interne : 002B97 ( PascalFrancis/Corpus ); précédent : 002B96; suivant : 002B98

Early detection of probable idiopathic Parkinson's disease : II. A prospective application of a diagnostic test battery

Auteurs : E. B. Jr Montgomery ; K. Lyons ; W. C. Koller

Source :

RBID : Pascal:00-0271640

Descripteurs français

English descriptors

Abstract

We developed a battery of tests, incorporating motor function, olfaction, and mood, that distinguishes between early mild, probable idiopathic Parkinson's disease (iPD), and normal control subjects. Here, we determined the PD Battery's ability to prospectively identify which patients with symptoms and signs suggestive of, but not yet diagnostic of, iPD who would subsequently be diagnosed as having iPD. Of 212 enrolled patients, 194 have been followed for at least 1 year. Among these 194, 59 were diagnosed with iPD, 40 as neurologically normal, and the remaining 106 with other neurologic conditions such as essential tremor. The test battery was 92% specific and 68% sensitive for iPD. The area under the Receiver Operating Characteristics curve was 0.88 for predicting which participants would subsequently be diagnosed as having iPD or as being neurologically normal.

Notice en format standard (ISO 2709)

Pour connaître la documentation sur le format Inist Standard.

pA  
A01 01  1    @0 0885-3185
A03   1    @0 Mov. disord.
A05       @2 15
A06       @2 3
A08 01  1  ENG  @1 Early detection of probable idiopathic Parkinson's disease : II. A prospective application of a diagnostic test battery
A11 01  1    @1 MONTGOMERY (E. B. JR)
A11 02  1    @1 LYONS (K.)
A11 03  1    @1 KOLLER (W. C.)
A14 01      @1 Departments of Neurology and Department of Neuroscience, Lerner Research Institute, Cleveland Clinic Foundation @2 Cleveland, Ohio @3 USA @Z 1 aut.
A14 02      @1 National Parkinson Foundation, University of Miami Medical Center @2 Miami, Florida @3 USA @Z 2 aut. @Z 3 aut.
A20       @1 474-478
A21       @1 2000
A23 01      @0 ENG
A43 01      @1 INIST @2 20953 @5 354000087348900070
A44       @0 0000 @1 © 2000 INIST-CNRS. All rights reserved.
A45       @0 5 ref.
A47 01  1    @0 00-0271640
A60       @1 P
A61       @0 A
A64 01  1    @0 Movement disorders
A66 01      @0 USA
C01 01    ENG  @0 We developed a battery of tests, incorporating motor function, olfaction, and mood, that distinguishes between early mild, probable idiopathic Parkinson's disease (iPD), and normal control subjects. Here, we determined the PD Battery's ability to prospectively identify which patients with symptoms and signs suggestive of, but not yet diagnostic of, iPD who would subsequently be diagnosed as having iPD. Of 212 enrolled patients, 194 have been followed for at least 1 year. Among these 194, 59 were diagnosed with iPD, 40 as neurologically normal, and the remaining 106 with other neurologic conditions such as essential tremor. The test battery was 92% specific and 68% sensitive for iPD. The area under the Receiver Operating Characteristics curve was 0.88 for predicting which participants would subsequently be diagnosed as having iPD or as being neurologically normal.
C02 01  X    @0 002B17G
C03 01  X  FRE  @0 Parkinson maladie @5 01
C03 01  X  ENG  @0 Parkinson disease @5 01
C03 01  X  SPA  @0 Parkinson enfermedad @5 01
C03 02  X  FRE  @0 Olfaction @5 04
C03 02  X  ENG  @0 Olfaction @5 04
C03 02  X  SPA  @0 Olfación @5 04
C03 03  X  FRE  @0 Mouvement @5 07
C03 03  X  ENG  @0 Motion @5 07
C03 03  X  SPA  @0 Movimiento @5 07
C03 04  X  FRE  @0 Humeur @5 10
C03 04  X  ENG  @0 Mood @5 10
C03 04  X  SPA  @0 Humor @5 10
C03 05  X  FRE  @0 Evaluation performance @5 16
C03 05  X  ENG  @0 Performance evaluation @5 16
C03 05  X  SPA  @0 Evaluación prestación @5 16
C03 06  X  FRE  @0 Dépistage @5 17
C03 06  X  ENG  @0 Medical screening @5 17
C03 06  X  SPA  @0 Descubrimiento @5 17
C03 07  X  FRE  @0 Précoce @5 18
C03 07  X  ENG  @0 Early @5 18
C03 07  X  SPA  @0 Precoz @5 18
C03 08  X  FRE  @0 Homme @5 20
C03 08  X  ENG  @0 Human @5 20
C03 08  X  SPA  @0 Hombre @5 20
C07 01  X  FRE  @0 Système nerveux pathologie @5 37
C07 01  X  ENG  @0 Nervous system diseases @5 37
C07 01  X  SPA  @0 Sistema nervioso patología @5 37
C07 02  X  FRE  @0 Système nerveux central pathologie @5 38
C07 02  X  ENG  @0 Central nervous system disease @5 38
C07 02  X  SPA  @0 Sistema nervosio central patología @5 38
C07 03  X  FRE  @0 Encéphale pathologie @5 39
C07 03  X  ENG  @0 Cerebral disorder @5 39
C07 03  X  SPA  @0 Encéfalo patología @5 39
C07 04  X  FRE  @0 Extrapyramidal syndrome @5 40
C07 04  X  ENG  @0 Extrapyramidal syndrome @5 40
C07 04  X  SPA  @0 Extrapiramidal síndrome @5 40
C07 05  X  FRE  @0 Maladie dégénérative @5 41
C07 05  X  ENG  @0 Degenerative disease @5 41
C07 05  X  SPA  @0 Enfermedad degenerativa @5 41
N21       @1 185

Format Inist (serveur)

NO : PASCAL 00-0271640 INIST
ET : Early detection of probable idiopathic Parkinson's disease : II. A prospective application of a diagnostic test battery
AU : MONTGOMERY (E. B. JR); LYONS (K.); KOLLER (W. C.)
AF : Departments of Neurology and Department of Neuroscience, Lerner Research Institute, Cleveland Clinic Foundation/Cleveland, Ohio/Etats-Unis (1 aut.); National Parkinson Foundation, University of Miami Medical Center/Miami, Florida/Etats-Unis (2 aut., 3 aut.)
DT : Publication en série; Niveau analytique
SO : Movement disorders; ISSN 0885-3185; Etats-Unis; Da. 2000; Vol. 15; No. 3; Pp. 474-478; Bibl. 5 ref.
LA : Anglais
EA : We developed a battery of tests, incorporating motor function, olfaction, and mood, that distinguishes between early mild, probable idiopathic Parkinson's disease (iPD), and normal control subjects. Here, we determined the PD Battery's ability to prospectively identify which patients with symptoms and signs suggestive of, but not yet diagnostic of, iPD who would subsequently be diagnosed as having iPD. Of 212 enrolled patients, 194 have been followed for at least 1 year. Among these 194, 59 were diagnosed with iPD, 40 as neurologically normal, and the remaining 106 with other neurologic conditions such as essential tremor. The test battery was 92% specific and 68% sensitive for iPD. The area under the Receiver Operating Characteristics curve was 0.88 for predicting which participants would subsequently be diagnosed as having iPD or as being neurologically normal.
CC : 002B17G
FD : Parkinson maladie; Olfaction; Mouvement; Humeur; Evaluation performance; Dépistage; Précoce; Homme
FG : Système nerveux pathologie; Système nerveux central pathologie; Encéphale pathologie; Extrapyramidal syndrome; Maladie dégénérative
ED : Parkinson disease; Olfaction; Motion; Mood; Performance evaluation; Medical screening; Early; Human
EG : Nervous system diseases; Central nervous system disease; Cerebral disorder; Extrapyramidal syndrome; Degenerative disease
SD : Parkinson enfermedad; Olfación; Movimiento; Humor; Evaluación prestación; Descubrimiento; Precoz; Hombre
LO : INIST-20953.354000087348900070
ID : 00-0271640

Links to Exploration step

Pascal:00-0271640

Le document en format XML

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<AF>Departments of Neurology and Department of Neuroscience, Lerner Research Institute, Cleveland Clinic Foundation/Cleveland, Ohio/Etats-Unis (1 aut.); National Parkinson Foundation, University of Miami Medical Center/Miami, Florida/Etats-Unis (2 aut., 3 aut.)</AF>
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<SD>Parkinson enfermedad; Olfación; Movimiento; Humor; Evaluación prestación; Descubrimiento; Precoz; Hombre</SD>
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