Pallidal stimulation reduces treatment‐induced dyskinesias in “minimal‐change” multiple system atrophy
Identifieur interne : 004E92 ( Main/Merge ); précédent : 004E91; suivant : 004E93Pallidal stimulation reduces treatment‐induced dyskinesias in “minimal‐change” multiple system atrophy
Auteurs : Yue Huang [Australie] ; Raymond Garrick [Australie] ; Raymond Cook [Australie] ; Dudley O'Sullivan [Australie] ; John Morris [Australie] ; Glenda M. Halliday [Australie]Source :
- Movement Disorders [ 0885-3185 ] ; 2005-08.
English descriptors
- KwdEn :
- Deep Brain Stimulation (methods), Dyskinesia, Drug-Induced (etiology), Dyskinesia, Drug-Induced (therapy), Female, Functional Laterality, Globus Pallidus (radiation effects), Humans, Immunohistochemistry, Levodopa (adverse effects), Magnetic Resonance Imaging (methods), Middle Aged, Multiple System Atrophy (physiopathology), Multiple System Atrophy (therapy), Nerve Tissue Proteins (metabolism), Neuropsychological Tests, Staining and Labeling, Synucleins, Ubiquitin (metabolism), dyskinesia, globus pallidus stimulation, multiple system atrophy, parkinsonism.
- MESH :
- chemical , adverse effects : Levodopa.
- etiology : Dyskinesia, Drug-Induced.
- chemical , metabolism : Nerve Tissue Proteins, Ubiquitin.
- methods : Deep Brain Stimulation, Magnetic Resonance Imaging.
- physiopathology : Multiple System Atrophy.
- radiation effects : Globus Pallidus.
- therapy : Dyskinesia, Drug-Induced, Multiple System Atrophy.
- Female, Functional Laterality, Humans, Immunohistochemistry, Middle Aged, Neuropsychological Tests, Staining and Labeling, Synucleins.
Abstract
Deep brain stimulation therapy is increasingly gaining acceptance in the management of levodopa‐induced dyskinesia and fluctuations in idiopathic Parkinson's disease. It is generally not recommended for the other forms of parkinsonism such as progressive supranuclear palsy or multiple system atrophy where the response to levodopa is usually poor and disease progression more rapid, making any benefit short‐lived. Here, we present an autopsy‐confirmed case of “minimal‐change” multiple system atrophy in whom pallidal stimulation surgery was effective in abolishing severe levodopa‐induced dyskinesia. © 2005 Movement Disorder Society
Url:
DOI: 10.1002/mds.20497
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<front><div type="abstract" xml:lang="en">Deep brain stimulation therapy is increasingly gaining acceptance in the management of levodopa‐induced dyskinesia and fluctuations in idiopathic Parkinson's disease. It is generally not recommended for the other forms of parkinsonism such as progressive supranuclear palsy or multiple system atrophy where the response to levodopa is usually poor and disease progression more rapid, making any benefit short‐lived. Here, we present an autopsy‐confirmed case of “minimal‐change” multiple system atrophy in whom pallidal stimulation surgery was effective in abolishing severe levodopa‐induced dyskinesia. © 2005 Movement Disorder Society</div>
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<front><div type="abstract" xml:lang="en">Deep brain stimulation therapy is increasingly gaining acceptance in the management of levodopa-induced dyskinesia and fluctuations in idiopathic Parkinson's disease. It is generally not recommended for the other forms of parkinsonism such as progressive supranuclear palsy or multiple system atrophy where the response to levodopa is usually poor and disease progression more rapid, making any benefit short-lived. Here, we present an autopsy-confirmed case of "minimal-change" multiple system atrophy in whom pallidal stimulation surgery was effective in abolishing severe levodopa-induced dyskinesia.</div>
</front>
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