Pallidal stimulation reduces treatment-induced dyskinesias in "minimal-change" multiple system atrophy.
Identifieur interne : 003066 ( PubMed/Corpus ); précédent : 003065; suivant : 003067Pallidal stimulation reduces treatment-induced dyskinesias in "minimal-change" multiple system atrophy.
Auteurs : Yue Huang ; Raymond Garrick ; Raymond Cook ; Dudley O'Sullivan ; John Morris ; Glenda M. HallidaySource :
- Movement disorders : official journal of the Movement Disorder Society [ 0885-3185 ] ; 2005.
English descriptors
- KwdEn :
- Deep Brain Stimulation (methods), Dyskinesia, Drug-Induced (etiology), Dyskinesia, Drug-Induced (therapy), Female, Functional Laterality, Globus Pallidus (radiation effects), Humans, Immunohistochemistry, Levodopa (adverse effects), Magnetic Resonance Imaging (methods), Middle Aged, Multiple System Atrophy (physiopathology), Multiple System Atrophy (therapy), Nerve Tissue Proteins (metabolism), Neuropsychological Tests, Staining and Labeling, Synucleins, Ubiquitin (metabolism).
- MESH :
- chemical , adverse effects : Levodopa.
- etiology : Dyskinesia, Drug-Induced.
- chemical , metabolism : Nerve Tissue Proteins, Ubiquitin.
- methods : Deep Brain Stimulation, Magnetic Resonance Imaging.
- physiopathology : Multiple System Atrophy.
- radiation effects : Globus Pallidus.
- therapy : Dyskinesia, Drug-Induced, Multiple System Atrophy.
- Female, Functional Laterality, Humans, Immunohistochemistry, Middle Aged, Neuropsychological Tests, Staining and Labeling, Synucleins.
Abstract
Deep brain stimulation therapy is increasingly gaining acceptance in the management of levodopa-induced dyskinesia and fluctuations in idiopathic Parkinson's disease. It is generally not recommended for the other forms of parkinsonism such as progressive supranuclear palsy or multiple system atrophy where the response to levodopa is usually poor and disease progression more rapid, making any benefit short-lived. Here, we present an autopsy-confirmed case of "minimal-change" multiple system atrophy in whom pallidal stimulation surgery was effective in abolishing severe levodopa-induced dyskinesia.
DOI: 10.1002/mds.20497
PubMed: 15852363
Links to Exploration step
pubmed:15852363Le document en format XML
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<affiliation><nlm:affiliation>Prince of Wales Medical Research Institute and University of New South Wales, Randwick, Australia.</nlm:affiliation>
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<author><name sortKey="Garrick, Raymond" sort="Garrick, Raymond" uniqKey="Garrick R" first="Raymond" last="Garrick">Raymond Garrick</name>
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<author><name sortKey="Cook, Raymond" sort="Cook, Raymond" uniqKey="Cook R" first="Raymond" last="Cook">Raymond Cook</name>
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<author><name sortKey="O Sullivan, Dudley" sort="O Sullivan, Dudley" uniqKey="O Sullivan D" first="Dudley" last="O'Sullivan">Dudley O'Sullivan</name>
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<author><name sortKey="Morris, John" sort="Morris, John" uniqKey="Morris J" first="John" last="Morris">John Morris</name>
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<author><name sortKey="Halliday, Glenda M" sort="Halliday, Glenda M" uniqKey="Halliday G" first="Glenda M" last="Halliday">Glenda M. Halliday</name>
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<term>Immunohistochemistry</term>
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<front><div type="abstract" xml:lang="en">Deep brain stimulation therapy is increasingly gaining acceptance in the management of levodopa-induced dyskinesia and fluctuations in idiopathic Parkinson's disease. It is generally not recommended for the other forms of parkinsonism such as progressive supranuclear palsy or multiple system atrophy where the response to levodopa is usually poor and disease progression more rapid, making any benefit short-lived. Here, we present an autopsy-confirmed case of "minimal-change" multiple system atrophy in whom pallidal stimulation surgery was effective in abolishing severe levodopa-induced dyskinesia.</div>
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<Abstract><AbstractText>Deep brain stimulation therapy is increasingly gaining acceptance in the management of levodopa-induced dyskinesia and fluctuations in idiopathic Parkinson's disease. It is generally not recommended for the other forms of parkinsonism such as progressive supranuclear palsy or multiple system atrophy where the response to levodopa is usually poor and disease progression more rapid, making any benefit short-lived. Here, we present an autopsy-confirmed case of "minimal-change" multiple system atrophy in whom pallidal stimulation surgery was effective in abolishing severe levodopa-induced dyskinesia.</AbstractText>
<CopyrightInformation>Copyright 2005 Movement Disorder Society</CopyrightInformation>
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