Movement Disorders (revue)

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Correlation between cardiac 123I-MIBG and odor identification in patients with Parkinson's disease and multiple system atrophy

Identifieur interne : 004C57 ( Main/Merge ); précédent : 004C56; suivant : 004C58

Correlation between cardiac 123I-MIBG and odor identification in patients with Parkinson's disease and multiple system atrophy

Auteurs : PHIL HYU LEE [Corée du Sud] ; SEUNG HYEON YEO [Corée du Sud] ; HYUN JOON KIM [Corée du Sud] ; HYO YOUNG YOUM [Corée du Sud]

Source :

RBID : Pascal:07-0021729

Descripteurs français

English descriptors

Abstract

We investigated an association between olfaction and cardiac 123I-metaiodobenzylguanidine (MIBG) uptake in patients with Parkinson's disease (PD) and multiple system atrophy (MSA). There was a significant positive correlation between cardiac MIBG uptake and the Cross-Cultural Smell Identification (CCSI) score in patients with PD (r = 0.56; P = 0.003) independent of the disease duration or clinical rating of motor status. However, patients with MSA did not show a significant correlation between cardiac MIBG uptake and the CCSI score. Our findings suggest that the functional losses of the olfactory and cardiac sympathetic systems are closely coupled in PD.

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Pascal:07-0021729

Le document en format XML

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<sup>123</sup>
I-metaiodobenzylguanidine (MIBG) uptake in patients with Parkinson's disease (PD) and multiple system atrophy (MSA). There was a significant positive correlation between cardiac MIBG uptake and the Cross-Cultural Smell Identification (CCSI) score in patients with PD (r = 0.56; P = 0.003) independent of the disease duration or clinical rating of motor status. However, patients with MSA did not show a significant correlation between cardiac MIBG uptake and the CCSI score. Our findings suggest that the functional losses of the olfactory and cardiac sympathetic systems are closely coupled in PD.</div>
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   |clé=     Pascal:07-0021729
   |texte=   Correlation between cardiac 123I-MIBG and odor identification in patients with Parkinson's disease and multiple system atrophy
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