Correlation between cardiac 123I-MIBG and odor identification in patients with Parkinson's disease and multiple system atrophy
Identifieur interne : 004C57 ( Main/Merge ); précédent : 004C56; suivant : 004C58Correlation between cardiac 123I-MIBG and odor identification in patients with Parkinson's disease and multiple system atrophy
Auteurs : PHIL HYU LEE [Corée du Sud] ; SEUNG HYEON YEO [Corée du Sud] ; HYUN JOON KIM [Corée du Sud] ; HYO YOUNG YOUM [Corée du Sud]Source :
- Movement disorders [ 0885-3185 ] ; 2006.
Descripteurs français
- Pascal (Inist)
- Wicri :
- topic : Homme.
English descriptors
Abstract
We investigated an association between olfaction and cardiac 123I-metaiodobenzylguanidine (MIBG) uptake in patients with Parkinson's disease (PD) and multiple system atrophy (MSA). There was a significant positive correlation between cardiac MIBG uptake and the Cross-Cultural Smell Identification (CCSI) score in patients with PD (r = 0.56; P = 0.003) independent of the disease duration or clinical rating of motor status. However, patients with MSA did not show a significant correlation between cardiac MIBG uptake and the CCSI score. Our findings suggest that the functional losses of the olfactory and cardiac sympathetic systems are closely coupled in PD.
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Pascal:07-0021729Le document en format XML
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I-MIBG and odor identification in patients with Parkinson's disease and multiple system atrophy</title>
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I-MIBG and odor identification in patients with Parkinson's disease and multiple system atrophy</title>
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<profileDesc><textClass><keywords scheme="KwdEn" xml:lang="en"><term>Human</term>
<term>Multiple system atrophy</term>
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<term>Parkinson disease</term>
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<keywords scheme="Pascal" xml:lang="fr"><term>Système nerveux pathologie</term>
<term>Parkinson maladie</term>
<term>Atrophie multisystématisée</term>
<term>Odeur</term>
<term>Homme</term>
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<front><div type="abstract" xml:lang="en">We investigated an association between olfaction and cardiac <sup>123</sup>
I-metaiodobenzylguanidine (MIBG) uptake in patients with Parkinson's disease (PD) and multiple system atrophy (MSA). There was a significant positive correlation between cardiac MIBG uptake and the Cross-Cultural Smell Identification (CCSI) score in patients with PD (r = 0.56; P = 0.003) independent of the disease duration or clinical rating of motor status. However, patients with MSA did not show a significant correlation between cardiac MIBG uptake and the CCSI score. Our findings suggest that the functional losses of the olfactory and cardiac sympathetic systems are closely coupled in PD.</div>
</front>
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<name sortKey="Hyun Joon Kim" sort="Hyun Joon Kim" uniqKey="Hyun Joon Kim" last="Hyun Joon Kim">HYUN JOON KIM</name>
<name sortKey="Seung Hyeon Yeo" sort="Seung Hyeon Yeo" uniqKey="Seung Hyeon Yeo" last="Seung Hyeon Yeo">SEUNG HYEON YEO</name>
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