Correlation between cardiac 123I-MIBG and odor identification in patients with Parkinson's disease and multiple system atrophy
Identifieur interne : 001902 ( PascalFrancis/Corpus ); précédent : 001901; suivant : 001903Correlation between cardiac 123I-MIBG and odor identification in patients with Parkinson's disease and multiple system atrophy
Auteurs : PHIL HYU LEE ; SEUNG HYEON YEO ; HYUN JOON KIM ; HYO YOUNG YOUMSource :
- Movement disorders [ 0885-3185 ] ; 2006.
Descripteurs français
- Pascal (Inist)
English descriptors
Abstract
We investigated an association between olfaction and cardiac 123I-metaiodobenzylguanidine (MIBG) uptake in patients with Parkinson's disease (PD) and multiple system atrophy (MSA). There was a significant positive correlation between cardiac MIBG uptake and the Cross-Cultural Smell Identification (CCSI) score in patients with PD (r = 0.56; P = 0.003) independent of the disease duration or clinical rating of motor status. However, patients with MSA did not show a significant correlation between cardiac MIBG uptake and the CCSI score. Our findings suggest that the functional losses of the olfactory and cardiac sympathetic systems are closely coupled in PD.
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Format Inist (serveur)
NO : | PASCAL 07-0021729 INIST |
---|---|
ET : | Correlation between cardiac 123I-MIBG and odor identification in patients with Parkinson's disease and multiple system atrophy |
AU : | PHIL HYU LEE; SEUNG HYEON YEO; HYUN JOON KIM; HYO YOUNG YOUM |
AF : | Department of Neurology, Ajou University College of Medicine/Suwon/Corée, République de (1 aut., 2 aut., 4 aut.); Department of Otolaryngology, Ajou University College of Medicine/Suwon/Corée, République de (3 aut.) |
DT : | Publication en série; Courte communication, note brève; Niveau analytique |
SO : | Movement disorders; ISSN 0885-3185; Etats-Unis; Da. 2006; Vol. 21; No. 11; Pp. 1975-1977; Bibl. 16 ref. |
LA : | Anglais |
EA : | We investigated an association between olfaction and cardiac 123I-metaiodobenzylguanidine (MIBG) uptake in patients with Parkinson's disease (PD) and multiple system atrophy (MSA). There was a significant positive correlation between cardiac MIBG uptake and the Cross-Cultural Smell Identification (CCSI) score in patients with PD (r = 0.56; P = 0.003) independent of the disease duration or clinical rating of motor status. However, patients with MSA did not show a significant correlation between cardiac MIBG uptake and the CCSI score. Our findings suggest that the functional losses of the olfactory and cardiac sympathetic systems are closely coupled in PD. |
CC : | 002B17; 002B17F; 002B17G |
FD : | Système nerveux pathologie; Parkinson maladie; Atrophie multisystématisée; Odeur; Homme |
FG : | Encéphale pathologie; Extrapyramidal syndrome; Maladie dégénérative; Système nerveux central pathologie |
ED : | Nervous system diseases; Parkinson disease; Multiple system atrophy; Odor; Human |
EG : | Cerebral disorder; Extrapyramidal syndrome; Degenerative disease; Central nervous system disease |
SD : | Sistema nervioso patología; Parkinson enfermedad; Atrofia multisistematizada; Olor; Hombre |
LO : | INIST-20953.354000158935070260 |
ID : | 07-0021729 |
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Pascal:07-0021729Le document en format XML
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<front><div type="abstract" xml:lang="en">We investigated an association between olfaction and cardiac <sup>123</sup>
I-metaiodobenzylguanidine (MIBG) uptake in patients with Parkinson's disease (PD) and multiple system atrophy (MSA). There was a significant positive correlation between cardiac MIBG uptake and the Cross-Cultural Smell Identification (CCSI) score in patients with PD (r = 0.56; P = 0.003) independent of the disease duration or clinical rating of motor status. However, patients with MSA did not show a significant correlation between cardiac MIBG uptake and the CCSI score. Our findings suggest that the functional losses of the olfactory and cardiac sympathetic systems are closely coupled in PD.</div>
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<ET>Correlation between cardiac <sup>123</sup>
I-MIBG and odor identification in patients with Parkinson's disease and multiple system atrophy</ET>
<AU>PHIL HYU LEE; SEUNG HYEON YEO; HYUN JOON KIM; HYO YOUNG YOUM</AU>
<AF>Department of Neurology, Ajou University College of Medicine/Suwon/Corée, République de (1 aut., 2 aut., 4 aut.); Department of Otolaryngology, Ajou University College of Medicine/Suwon/Corée, République de (3 aut.)</AF>
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<LA>Anglais</LA>
<EA>We investigated an association between olfaction and cardiac <sup>123</sup>
I-metaiodobenzylguanidine (MIBG) uptake in patients with Parkinson's disease (PD) and multiple system atrophy (MSA). There was a significant positive correlation between cardiac MIBG uptake and the Cross-Cultural Smell Identification (CCSI) score in patients with PD (r = 0.56; P = 0.003) independent of the disease duration or clinical rating of motor status. However, patients with MSA did not show a significant correlation between cardiac MIBG uptake and the CCSI score. Our findings suggest that the functional losses of the olfactory and cardiac sympathetic systems are closely coupled in PD.</EA>
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