Cardiac 123I‐MIBG scintigraphy in patients with essential tremor
Identifieur interne : 004862 ( Main/Merge ); précédent : 004861; suivant : 004863Cardiac 123I‐MIBG scintigraphy in patients with essential tremor
Auteurs : Phil Hyu Lee [Corée du Sud] ; Ji Won Kim [Corée du Sud] ; Oh Young Bang [Corée du Sud] ; In Soo Joo [Corée du Sud] ; Seok-Nam Yoon [Corée du Sud] ; Kyoon Huh [Corée du Sud]Source :
- Movement Disorders [ 0885-3185 ] ; 2006-08.
English descriptors
- KwdEn :
- 3-Iodobenzylguanidine (diagnostic use), Aged, Aged, 80 and over, Diagnosis, Differential, Essential Tremor (physiopathology), Essential Tremor (radionuclide imaging), Female, Heart (radionuclide imaging), Heart Diseases (epidemiology), Heart Diseases (radionuclide imaging), Humans, Iodine Radioisotopes (diagnostic use), Male, Middle Aged, Parkinson Disease (physiopathology), Parkinson Disease (radionuclide imaging), Parkinson's disease, Radiopharmaceuticals (diagnostic use), cardiac MIBG, essential tremor.
- MESH :
- chemical , diagnostic use : 3-Iodobenzylguanidine, Iodine Radioisotopes, Radiopharmaceuticals.
- epidemiology : Heart Diseases.
- physiopathology : Essential Tremor, Parkinson Disease.
- radionuclide imaging : Essential Tremor, Heart, Heart Diseases, Parkinson Disease.
- Aged, Aged, 80 and over, Diagnosis, Differential, Female, Humans, Male, Middle Aged.
Abstract
In some cases, it is difficult to differentiate essential tremor (ET) from Parkinson's disease (PD), especially in the early stages of the disease. We investigated cardiac sympathetic dysfunction using 123I‐metaiodobenzylguanidine (MIBG) myocardial scintigraphy in 22 patients with ET, in comparison with early PD and tremor‐dominant PD (TDPD). The mean ratio of 123I‐MIBG uptake in the region of interest in the heart to that in the mediastinum (H/M ratio) was significantly greater in patients with ET (1.99 ± 0.21) than in those with either TDPD (1.28 ± 0.11) or early PD (1.28 ± 0.17; each P < 0.001). The H/M ratio in all patients with ET was greater than two standard deviations above the range of the ratio in the patients with early PD or TDPD. © 2006 Movement Disorder Society
Url:
DOI: 10.1002/mds.20908
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<front><div type="abstract" xml:lang="fr">In some cases, it is difficult to differentiate essential tremor (ET) from Parkinson's disease (PD), especially in the early stages of the disease. We investigated cardiac sympathetic dysfunction using 123I‐metaiodobenzylguanidine (MIBG) myocardial scintigraphy in 22 patients with ET, in comparison with early PD and tremor‐dominant PD (TDPD). The mean ratio of 123I‐MIBG uptake in the region of interest in the heart to that in the mediastinum (H/M ratio) was significantly greater in patients with ET (1.99 ± 0.21) than in those with either TDPD (1.28 ± 0.11) or early PD (1.28 ± 0.17; each P < 0.001). The H/M ratio in all patients with ET was greater than two standard deviations above the range of the ratio in the patients with early PD or TDPD. © 2006 Movement Disorder Society</div>
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<front><div type="abstract" xml:lang="fr">In some cases, it is difficult to differentiate essential tremor (ET) from Parkinson's disease (PD), especially in the early stages of the disease. We investigated cardiac sympathetic dysfunction using 123I‐metaiodobenzylguanidine (MIBG) myocardial scintigraphy in 22 patients with ET, in comparison with early PD and tremor‐dominant PD (TDPD). The mean ratio of 123I‐MIBG uptake in the region of interest in the heart to that in the mediastinum (H/M ratio) was significantly greater in patients with ET (1.99 ± 0.21) than in those with either TDPD (1.28 ± 0.11) or early PD (1.28 ± 0.17; each P < 0.001). The H/M ratio in all patients with ET was greater than two standard deviations above the range of the ratio in the patients with early PD or TDPD. © 2006 Movement Disorder Society</div>
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<front><div type="abstract" xml:lang="en">In some cases, it is difficult to differentiate essential tremor (ET) from Parkinson's disease (PD), especially in the early stages of the disease. We investigated cardiac sympathetic dysfunction using (123)I-metaiodobenzylguanidine (MIBG) myocardial scintigraphy in 22 patients with ET, in comparison with early PD and tremor-dominant PD (TDPD). The mean ratio of (123)I-MIBG uptake in the region of interest in the heart to that in the mediastinum (H/M ratio) was significantly greater in patients with ET (1.99 +/- 0.21) than in those with either TDPD (1.28 +/- 0.11) or early PD (1.28 +/- 0.17; each P < 0.001). The H/M ratio in all patients with ET was greater than two standard deviations above the range of the ratio in the patients with early PD or TDPD.</div>
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