Cardiac 123I-MIBG scintigraphy in patients with essential tremor.
Identifieur interne : 001665 ( Ncbi/Checkpoint ); précédent : 001664; suivant : 001666Cardiac 123I-MIBG scintigraphy in patients with essential tremor.
Auteurs : Phil Hyu Lee [Corée du Sud] ; Ji Won Kim ; Oh Young Bang ; In Soo Joo ; Seok-Nam Yoon ; Kyoon HuhSource :
- Movement disorders : official journal of the Movement Disorder Society [ 0885-3185 ] ; 2006.
English descriptors
- KwdEn :
- 3-Iodobenzylguanidine (diagnostic use), Aged, Aged, 80 and over, Diagnosis, Differential, Essential Tremor (physiopathology), Essential Tremor (radionuclide imaging), Female, Heart (radionuclide imaging), Heart Diseases (epidemiology), Heart Diseases (radionuclide imaging), Humans, Iodine Radioisotopes (diagnostic use), Male, Middle Aged, Parkinson Disease (physiopathology), Parkinson Disease (radionuclide imaging), Radiopharmaceuticals (diagnostic use).
- MESH :
- chemical , diagnostic use : 3-Iodobenzylguanidine, Iodine Radioisotopes, Radiopharmaceuticals.
- epidemiology : Heart Diseases.
- physiopathology : Essential Tremor, Parkinson Disease.
- radionuclide imaging : Essential Tremor, Heart, Heart Diseases, Parkinson Disease.
- Aged, Aged, 80 and over, Diagnosis, Differential, Female, Humans, Male, Middle Aged.
Abstract
In some cases, it is difficult to differentiate essential tremor (ET) from Parkinson's disease (PD), especially in the early stages of the disease. We investigated cardiac sympathetic dysfunction using (123)I-metaiodobenzylguanidine (MIBG) myocardial scintigraphy in 22 patients with ET, in comparison with early PD and tremor-dominant PD (TDPD). The mean ratio of (123)I-MIBG uptake in the region of interest in the heart to that in the mediastinum (H/M ratio) was significantly greater in patients with ET (1.99 +/- 0.21) than in those with either TDPD (1.28 +/- 0.11) or early PD (1.28 +/- 0.17; each P < 0.001). The H/M ratio in all patients with ET was greater than two standard deviations above the range of the ratio in the patients with early PD or TDPD.
DOI: 10.1002/mds.20908
PubMed: 16671077
Affiliations:
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pubmed:16671077Le document en format XML
<record><TEI><teiHeader><fileDesc><titleStmt><title xml:lang="en">Cardiac 123I-MIBG scintigraphy in patients with essential tremor.</title><author><name sortKey="Lee, Phil Hyu" sort="Lee, Phil Hyu" uniqKey="Lee P" first="Phil Hyu" last="Lee">Phil Hyu Lee</name><affiliation wicri:level="1"><nlm:affiliation>Department of Neurology, Ajou University School of Medicine, Suwon, South Korea. phisland@chol.com</nlm:affiliation><country xml:lang="fr">Corée du Sud</country><wicri:regionArea>Department of Neurology, Ajou University School of Medicine, Suwon</wicri:regionArea><wicri:noRegion>Suwon</wicri:noRegion></affiliation></author><author><name sortKey="Kim, Ji Won" sort="Kim, Ji Won" uniqKey="Kim J" first="Ji Won" last="Kim">Ji Won Kim</name></author><author><name sortKey="Bang, Oh Young" sort="Bang, Oh Young" uniqKey="Bang O" first="Oh Young" last="Bang">Oh Young Bang</name></author><author><name sortKey="Joo, In Soo" sort="Joo, In Soo" uniqKey="Joo I" first="In Soo" last="Joo">In Soo Joo</name></author><author><name sortKey="Yoon, Seok Nam" sort="Yoon, Seok Nam" uniqKey="Yoon S" first="Seok-Nam" last="Yoon">Seok-Nam Yoon</name></author><author><name sortKey="Huh, Kyoon" sort="Huh, Kyoon" uniqKey="Huh K" first="Kyoon" last="Huh">Kyoon Huh</name></author></titleStmt><publicationStmt><idno type="wicri:source">PubMed</idno><date when="2006">2006</date><idno type="doi">10.1002/mds.20908</idno><idno type="RBID">pubmed:16671077</idno><idno type="pmid">16671077</idno><idno type="wicri:Area/PubMed/Corpus">002C69</idno><idno type="wicri:Area/PubMed/Curation">002C69</idno><idno type="wicri:Area/PubMed/Checkpoint">002E36</idno><idno type="wicri:Area/Ncbi/Merge">001665</idno><idno type="wicri:Area/Ncbi/Curation">001665</idno><idno type="wicri:Area/Ncbi/Checkpoint">001665</idno></publicationStmt><sourceDesc><biblStruct><analytic><title xml:lang="en">Cardiac 123I-MIBG scintigraphy in patients with essential tremor.</title><author><name sortKey="Lee, Phil Hyu" sort="Lee, Phil Hyu" uniqKey="Lee P" first="Phil Hyu" last="Lee">Phil Hyu Lee</name><affiliation wicri:level="1"><nlm:affiliation>Department of Neurology, Ajou University School of Medicine, Suwon, South Korea. phisland@chol.com</nlm:affiliation><country xml:lang="fr">Corée du Sud</country><wicri:regionArea>Department of Neurology, Ajou University School of Medicine, Suwon</wicri:regionArea><wicri:noRegion>Suwon</wicri:noRegion></affiliation></author><author><name sortKey="Kim, Ji Won" sort="Kim, Ji Won" uniqKey="Kim J" first="Ji Won" last="Kim">Ji Won Kim</name></author><author><name sortKey="Bang, Oh Young" sort="Bang, Oh Young" uniqKey="Bang O" first="Oh Young" last="Bang">Oh Young Bang</name></author><author><name sortKey="Joo, In Soo" sort="Joo, In Soo" uniqKey="Joo I" first="In Soo" last="Joo">In Soo Joo</name></author><author><name sortKey="Yoon, Seok Nam" sort="Yoon, Seok Nam" uniqKey="Yoon S" first="Seok-Nam" last="Yoon">Seok-Nam Yoon</name></author><author><name sortKey="Huh, Kyoon" sort="Huh, Kyoon" uniqKey="Huh K" first="Kyoon" last="Huh">Kyoon Huh</name></author></analytic><series><title level="j">Movement disorders : official journal of the Movement Disorder Society</title><idno type="ISSN">0885-3185</idno><imprint><date when="2006" type="published">2006</date></imprint></series></biblStruct></sourceDesc></fileDesc><profileDesc><textClass><keywords scheme="KwdEn" xml:lang="en"><term>3-Iodobenzylguanidine (diagnostic use)</term><term>Aged</term><term>Aged, 80 and over</term><term>Diagnosis, Differential</term><term>Essential Tremor (physiopathology)</term><term>Essential Tremor (radionuclide imaging)</term><term>Female</term><term>Heart (radionuclide imaging)</term><term>Heart Diseases (epidemiology)</term><term>Heart Diseases (radionuclide imaging)</term><term>Humans</term><term>Iodine Radioisotopes (diagnostic use)</term><term>Male</term><term>Middle Aged</term><term>Parkinson Disease (physiopathology)</term><term>Parkinson Disease (radionuclide imaging)</term><term>Radiopharmaceuticals (diagnostic use)</term></keywords><keywords scheme="MESH" type="chemical" qualifier="diagnostic use" xml:lang="en"><term>3-Iodobenzylguanidine</term><term>Iodine Radioisotopes</term><term>Radiopharmaceuticals</term></keywords><keywords scheme="MESH" qualifier="epidemiology" xml:lang="en"><term>Heart Diseases</term></keywords><keywords scheme="MESH" qualifier="physiopathology" xml:lang="en"><term>Essential Tremor</term><term>Parkinson Disease</term></keywords><keywords scheme="MESH" qualifier="radionuclide imaging" xml:lang="en"><term>Essential Tremor</term><term>Heart</term><term>Heart Diseases</term><term>Parkinson Disease</term></keywords><keywords scheme="MESH" xml:lang="en"><term>Aged</term><term>Aged, 80 and over</term><term>Diagnosis, Differential</term><term>Female</term><term>Humans</term><term>Male</term><term>Middle Aged</term></keywords></textClass></profileDesc></teiHeader><front><div type="abstract" xml:lang="en">In some cases, it is difficult to differentiate essential tremor (ET) from Parkinson's disease (PD), especially in the early stages of the disease. We investigated cardiac sympathetic dysfunction using (123)I-metaiodobenzylguanidine (MIBG) myocardial scintigraphy in 22 patients with ET, in comparison with early PD and tremor-dominant PD (TDPD). The mean ratio of (123)I-MIBG uptake in the region of interest in the heart to that in the mediastinum (H/M ratio) was significantly greater in patients with ET (1.99 +/- 0.21) than in those with either TDPD (1.28 +/- 0.11) or early PD (1.28 +/- 0.17; each P < 0.001). The H/M ratio in all patients with ET was greater than two standard deviations above the range of the ratio in the patients with early PD or TDPD.</div></front></TEI><affiliations><list><country><li>Corée du Sud</li></country></list><tree><noCountry><name sortKey="Bang, Oh Young" sort="Bang, Oh Young" uniqKey="Bang O" first="Oh Young" last="Bang">Oh Young Bang</name><name sortKey="Huh, Kyoon" sort="Huh, Kyoon" uniqKey="Huh K" first="Kyoon" last="Huh">Kyoon Huh</name><name sortKey="Joo, In Soo" sort="Joo, In Soo" uniqKey="Joo I" first="In Soo" last="Joo">In Soo Joo</name><name sortKey="Kim, Ji Won" sort="Kim, Ji Won" uniqKey="Kim J" first="Ji Won" last="Kim">Ji Won Kim</name><name sortKey="Yoon, Seok Nam" sort="Yoon, Seok Nam" uniqKey="Yoon S" first="Seok-Nam" last="Yoon">Seok-Nam Yoon</name></noCountry><country name="Corée du Sud"><noRegion><name sortKey="Lee, Phil Hyu" sort="Lee, Phil Hyu" uniqKey="Lee P" first="Phil Hyu" last="Lee">Phil Hyu Lee</name></noRegion></country></tree></affiliations></record>Pour manipuler ce document sous Unix (Dilib)
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