Movement Disorders (revue)

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Cardiac 123I‐MIBG scintigraphy in patients with essential tremor

Identifieur interne : 002008 ( Istex/Checkpoint ); précédent : 002007; suivant : 002009

Cardiac 123I‐MIBG scintigraphy in patients with essential tremor

Auteurs : Phil Hyu Lee [Corée du Sud] ; Ji Won Kim [Corée du Sud] ; Oh Young Bang [Corée du Sud] ; In Soo Joo [Corée du Sud] ; Seok-Nam Yoon [Corée du Sud] ; Kyoon Huh [Corée du Sud]

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RBID : ISTEX:61CD75D45066B942C39B43FDFE3DFB551AB1FCA3

English descriptors

Abstract

In some cases, it is difficult to differentiate essential tremor (ET) from Parkinson's disease (PD), especially in the early stages of the disease. We investigated cardiac sympathetic dysfunction using 123I‐metaiodobenzylguanidine (MIBG) myocardial scintigraphy in 22 patients with ET, in comparison with early PD and tremor‐dominant PD (TDPD). The mean ratio of 123I‐MIBG uptake in the region of interest in the heart to that in the mediastinum (H/M ratio) was significantly greater in patients with ET (1.99 ± 0.21) than in those with either TDPD (1.28 ± 0.11) or early PD (1.28 ± 0.17; each P < 0.001). The H/M ratio in all patients with ET was greater than two standard deviations above the range of the ratio in the patients with early PD or TDPD. © 2006 Movement Disorder Society

Url:
DOI: 10.1002/mds.20908


Affiliations:


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ISTEX:61CD75D45066B942C39B43FDFE3DFB551AB1FCA3

Le document en format XML

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<title level="j">Movement Disorders</title>
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<div type="abstract" xml:lang="fr">In some cases, it is difficult to differentiate essential tremor (ET) from Parkinson's disease (PD), especially in the early stages of the disease. We investigated cardiac sympathetic dysfunction using 123I‐metaiodobenzylguanidine (MIBG) myocardial scintigraphy in 22 patients with ET, in comparison with early PD and tremor‐dominant PD (TDPD). The mean ratio of 123I‐MIBG uptake in the region of interest in the heart to that in the mediastinum (H/M ratio) was significantly greater in patients with ET (1.99 ± 0.21) than in those with either TDPD (1.28 ± 0.11) or early PD (1.28 ± 0.17; each P < 0.001). The H/M ratio in all patients with ET was greater than two standard deviations above the range of the ratio in the patients with early PD or TDPD. © 2006 Movement Disorder Society</div>
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