Unilateral lower limb rest tremor is not necessarily a presenting symptom of Parkinson's disease
Identifieur interne : 001D57 ( Main/Merge ); précédent : 001D56; suivant : 001D58Unilateral lower limb rest tremor is not necessarily a presenting symptom of Parkinson's disease
Auteurs : Mark A. Hellmann [Israël] ; Eldad Melamed [Israël] ; Adam P. Steinmetz [Israël] ; Ruth Djaldetti [Israël]Source :
- Movement Disorders [ 0885-3185 ] ; 2010-05-15.
English descriptors
- KwdEn :
- Diagnosis, Differential, Female, Functional Laterality (physiology), Humans, Lower Extremity (physiopathology), Male, Middle Aged, Parkinson Disease (diagnosis), Parkinson Disease (physiopathology), Parkinson's disease, Severity of Illness Index, Tremor (diagnosis), Tremor (physiopathology), lower limb, multiple system atrophy, tremor.
- MESH :
- diagnosis : Parkinson Disease, Tremor.
- physiology : Functional Laterality.
- physiopathology : Lower Extremity, Parkinson Disease, Tremor.
- Diagnosis, Differential, Female, Humans, Male, Middle Aged, Severity of Illness Index.
Abstract
Lower leg rest tremor is an uncommon symptom of neurological disease. Review of the files of 16 patients who presented with lower leg tremor (average age 58 ± 16 years; average disease duration 6.8 ± 8.5 years) yielded a diagnosis of Parkinson's disease (PD) in 5 and probable multiple system atrophy (MSA) in 3. In 4 patients with an indeterminate diagnosis, cardiac MIBG SPECT was positive in 3, indicating PD, and negative in one, suggesting MSA. Two patients each had psychogenic tremor and drug‐induced parkinsonism. Although lower leg tremor is considered an unusual presentation of PD, it should raise suspicions of MSA and other neurodegenerative disorders. © 2010 Movement Disorder Society
Url:
DOI: 10.1002/mds.23030
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<front><div type="abstract" xml:lang="en">Lower leg rest tremor is an uncommon symptom of neurological disease. Review of the files of 16 patients who presented with lower leg tremor (average age 58 +/- 16 years; average disease duration 6.8 +/- 8.5 years) yielded a diagnosis of Parkinson's disease (PD) in 5 and probable multiple system atrophy (MSA) in 3. In 4 patients with an indeterminate diagnosis, cardiac MIBG SPECT was positive in 3, indicating PD, and negative in one, suggesting MSA. Two patients each had psychogenic tremor and drug-induced parkinsonism. Although lower leg tremor is considered an unusual presentation of PD, it should raise suspicions of MSA and other neurodegenerative disorders.</div>
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