Unilateral lower limb rest tremor is not necessarily a presenting symptom of Parkinson's disease.
Identifieur interne : 002A81 ( Ncbi/Checkpoint ); précédent : 002A80; suivant : 002A82Unilateral lower limb rest tremor is not necessarily a presenting symptom of Parkinson's disease.
Auteurs : Mark A. Hellmann [Israël] ; Eldad Melamed ; Adam P. Steinmetz ; Ruth DjaldettiSource :
- Movement disorders : official journal of the Movement Disorder Society [ 1531-8257 ] ; 2010.
English descriptors
- KwdEn :
- MESH :
- diagnosis : Parkinson Disease, Tremor.
- physiology : Functional Laterality.
- physiopathology : Lower Extremity, Parkinson Disease, Tremor.
- Diagnosis, Differential, Female, Humans, Male, Middle Aged, Severity of Illness Index.
Abstract
Lower leg rest tremor is an uncommon symptom of neurological disease. Review of the files of 16 patients who presented with lower leg tremor (average age 58 +/- 16 years; average disease duration 6.8 +/- 8.5 years) yielded a diagnosis of Parkinson's disease (PD) in 5 and probable multiple system atrophy (MSA) in 3. In 4 patients with an indeterminate diagnosis, cardiac MIBG SPECT was positive in 3, indicating PD, and negative in one, suggesting MSA. Two patients each had psychogenic tremor and drug-induced parkinsonism. Although lower leg tremor is considered an unusual presentation of PD, it should raise suspicions of MSA and other neurodegenerative disorders.
DOI: 10.1002/mds.23030
PubMed: 20198647
Affiliations:
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pubmed:20198647Le document en format XML
<record><TEI><teiHeader><fileDesc><titleStmt><title xml:lang="en">Unilateral lower limb rest tremor is not necessarily a presenting symptom of Parkinson's disease.</title><author><name sortKey="Hellmann, Mark A" sort="Hellmann, Mark A" uniqKey="Hellmann M" first="Mark A" last="Hellmann">Mark A. Hellmann</name><affiliation wicri:level="1"><nlm:affiliation>Department of Neurology and Nuclear Medicine, Rabin Medical Center, Petah Tiqwa, Israel. markh@clalit.org.il</nlm:affiliation><country xml:lang="fr">Israël</country><wicri:regionArea>Department of Neurology and Nuclear Medicine, Rabin Medical Center, Petah Tiqwa</wicri:regionArea><wicri:noRegion>Petah Tiqwa</wicri:noRegion></affiliation></author><author><name sortKey="Melamed, Eldad" sort="Melamed, Eldad" uniqKey="Melamed E" first="Eldad" last="Melamed">Eldad Melamed</name></author><author><name sortKey="Steinmetz, Adam P" sort="Steinmetz, Adam P" uniqKey="Steinmetz A" first="Adam P" last="Steinmetz">Adam P. Steinmetz</name></author><author><name sortKey="Djaldetti, Ruth" sort="Djaldetti, Ruth" uniqKey="Djaldetti R" first="Ruth" last="Djaldetti">Ruth Djaldetti</name></author></titleStmt><publicationStmt><idno type="wicri:source">PubMed</idno><date when="2010">2010</date><idno type="doi">10.1002/mds.23030</idno><idno type="RBID">pubmed:20198647</idno><idno type="pmid">20198647</idno><idno type="wicri:Area/PubMed/Corpus">001921</idno><idno type="wicri:Area/PubMed/Curation">001921</idno><idno type="wicri:Area/PubMed/Checkpoint">001528</idno><idno type="wicri:Area/Ncbi/Merge">002A81</idno><idno type="wicri:Area/Ncbi/Curation">002A81</idno><idno type="wicri:Area/Ncbi/Checkpoint">002A81</idno></publicationStmt><sourceDesc><biblStruct><analytic><title xml:lang="en">Unilateral lower limb rest tremor is not necessarily a presenting symptom of Parkinson's disease.</title><author><name sortKey="Hellmann, Mark A" sort="Hellmann, Mark A" uniqKey="Hellmann M" first="Mark A" last="Hellmann">Mark A. Hellmann</name><affiliation wicri:level="1"><nlm:affiliation>Department of Neurology and Nuclear Medicine, Rabin Medical Center, Petah Tiqwa, Israel. markh@clalit.org.il</nlm:affiliation><country xml:lang="fr">Israël</country><wicri:regionArea>Department of Neurology and Nuclear Medicine, Rabin Medical Center, Petah Tiqwa</wicri:regionArea><wicri:noRegion>Petah Tiqwa</wicri:noRegion></affiliation></author><author><name sortKey="Melamed, Eldad" sort="Melamed, Eldad" uniqKey="Melamed E" first="Eldad" last="Melamed">Eldad Melamed</name></author><author><name sortKey="Steinmetz, Adam P" sort="Steinmetz, Adam P" uniqKey="Steinmetz A" first="Adam P" last="Steinmetz">Adam P. Steinmetz</name></author><author><name sortKey="Djaldetti, Ruth" sort="Djaldetti, Ruth" uniqKey="Djaldetti R" first="Ruth" last="Djaldetti">Ruth Djaldetti</name></author></analytic><series><title level="j">Movement disorders : official journal of the Movement Disorder Society</title><idno type="eISSN">1531-8257</idno><imprint><date when="2010" type="published">2010</date></imprint></series></biblStruct></sourceDesc></fileDesc><profileDesc><textClass><keywords scheme="KwdEn" xml:lang="en"><term>Diagnosis, Differential</term><term>Female</term><term>Functional Laterality (physiology)</term><term>Humans</term><term>Lower Extremity (physiopathology)</term><term>Male</term><term>Middle Aged</term><term>Parkinson Disease (diagnosis)</term><term>Parkinson Disease (physiopathology)</term><term>Severity of Illness Index</term><term>Tremor (diagnosis)</term><term>Tremor (physiopathology)</term></keywords><keywords scheme="MESH" qualifier="diagnosis" xml:lang="en"><term>Parkinson Disease</term><term>Tremor</term></keywords><keywords scheme="MESH" qualifier="physiology" xml:lang="en"><term>Functional Laterality</term></keywords><keywords scheme="MESH" qualifier="physiopathology" xml:lang="en"><term>Lower Extremity</term><term>Parkinson Disease</term><term>Tremor</term></keywords><keywords scheme="MESH" xml:lang="en"><term>Diagnosis, Differential</term><term>Female</term><term>Humans</term><term>Male</term><term>Middle Aged</term><term>Severity of Illness Index</term></keywords></textClass></profileDesc></teiHeader><front><div type="abstract" xml:lang="en">Lower leg rest tremor is an uncommon symptom of neurological disease. Review of the files of 16 patients who presented with lower leg tremor (average age 58 +/- 16 years; average disease duration 6.8 +/- 8.5 years) yielded a diagnosis of Parkinson's disease (PD) in 5 and probable multiple system atrophy (MSA) in 3. In 4 patients with an indeterminate diagnosis, cardiac MIBG SPECT was positive in 3, indicating PD, and negative in one, suggesting MSA. Two patients each had psychogenic tremor and drug-induced parkinsonism. Although lower leg tremor is considered an unusual presentation of PD, it should raise suspicions of MSA and other neurodegenerative disorders.</div></front></TEI><affiliations><list><country><li>Israël</li></country></list><tree><noCountry><name sortKey="Djaldetti, Ruth" sort="Djaldetti, Ruth" uniqKey="Djaldetti R" first="Ruth" last="Djaldetti">Ruth Djaldetti</name><name sortKey="Melamed, Eldad" sort="Melamed, Eldad" uniqKey="Melamed E" first="Eldad" last="Melamed">Eldad Melamed</name><name sortKey="Steinmetz, Adam P" sort="Steinmetz, Adam P" uniqKey="Steinmetz A" first="Adam P" last="Steinmetz">Adam P. Steinmetz</name></noCountry><country name="Israël"><noRegion><name sortKey="Hellmann, Mark A" sort="Hellmann, Mark A" uniqKey="Hellmann M" first="Mark A" last="Hellmann">Mark A. Hellmann</name></noRegion></country></tree></affiliations></record>Pour manipuler ce document sous Unix (Dilib)
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