Movement Disorders (revue)

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Unilateral lower limb rest tremor is not necessarily a presenting symptom of Parkinson's disease

Identifieur interne : 001358 ( Istex/Corpus ); précédent : 001357; suivant : 001359

Unilateral lower limb rest tremor is not necessarily a presenting symptom of Parkinson's disease

Auteurs : Mark A. Hellmann ; Eldad Melamed ; Adam P. Steinmetz ; Ruth Djaldetti

Source :

RBID : ISTEX:665BDB85938B794F4E12B9AED88EA6D942B36300

English descriptors

Abstract

Lower leg rest tremor is an uncommon symptom of neurological disease. Review of the files of 16 patients who presented with lower leg tremor (average age 58 ± 16 years; average disease duration 6.8 ± 8.5 years) yielded a diagnosis of Parkinson's disease (PD) in 5 and probable multiple system atrophy (MSA) in 3. In 4 patients with an indeterminate diagnosis, cardiac MIBG SPECT was positive in 3, indicating PD, and negative in one, suggesting MSA. Two patients each had psychogenic tremor and drug‐induced parkinsonism. Although lower leg tremor is considered an unusual presentation of PD, it should raise suspicions of MSA and other neurodegenerative disorders. © 2010 Movement Disorder Society

Url:
DOI: 10.1002/mds.23030

Links to Exploration step

ISTEX:665BDB85938B794F4E12B9AED88EA6D942B36300

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</titleInfo>
<titleInfo type="alternative" contentType="CDATA" lang="en">
<title>Unilateral lower limb rest tremor is not necessarily a presenting symptom of Parkinson's disease</title>
</titleInfo>
<name type="personal">
<namePart type="given">Mark A.</namePart>
<namePart type="family">Hellmann</namePart>
<namePart type="termsOfAddress">MD</namePart>
<affiliation>Department of Neurology and Nuclear Medicine, Rabin Medical Center, Beilinson Campus, Petah Tiqwa, Israel</affiliation>
<affiliation>Sackler Faculty of Medicine, Tel Aviv University, Tel Aviv, Israel</affiliation>
<description>Correspondence: Department of Neurology, Rabin Medical Center, Beilinson Campus, Petah Tiqwa 49100, Israel</description>
<role>
<roleTerm type="text">author</roleTerm>
</role>
</name>
<name type="personal">
<namePart type="given">Eldad</namePart>
<namePart type="family">Melamed</namePart>
<namePart type="termsOfAddress">MD</namePart>
<affiliation>Department of Neurology and Nuclear Medicine, Rabin Medical Center, Beilinson Campus, Petah Tiqwa, Israel</affiliation>
<affiliation>Sackler Faculty of Medicine, Tel Aviv University, Tel Aviv, Israel</affiliation>
<role>
<roleTerm type="text">author</roleTerm>
</role>
</name>
<name type="personal">
<namePart type="given">Adam P.</namePart>
<namePart type="family">Steinmetz</namePart>
<namePart type="termsOfAddress">MD</namePart>
<affiliation>Department of Neurology and Nuclear Medicine, Rabin Medical Center, Beilinson Campus, Petah Tiqwa, Israel</affiliation>
<affiliation>Sackler Faculty of Medicine, Tel Aviv University, Tel Aviv, Israel</affiliation>
<role>
<roleTerm type="text">author</roleTerm>
</role>
</name>
<name type="personal">
<namePart type="given">Ruth</namePart>
<namePart type="family">Djaldetti</namePart>
<namePart type="termsOfAddress">MD</namePart>
<affiliation>Department of Neurology and Nuclear Medicine, Rabin Medical Center, Beilinson Campus, Petah Tiqwa, Israel</affiliation>
<affiliation>Sackler Faculty of Medicine, Tel Aviv University, Tel Aviv, Israel</affiliation>
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<dateIssued encoding="w3cdtf">2010-05-15</dateIssued>
<dateCaptured encoding="w3cdtf">2009-07-14</dateCaptured>
<dateValid encoding="w3cdtf">2009-12-26</dateValid>
<copyrightDate encoding="w3cdtf">2010</copyrightDate>
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<languageTerm type="code" authority="rfc3066">en</languageTerm>
<languageTerm type="code" authority="iso639-2b">eng</languageTerm>
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<abstract lang="en">Lower leg rest tremor is an uncommon symptom of neurological disease. Review of the files of 16 patients who presented with lower leg tremor (average age 58 ± 16 years; average disease duration 6.8 ± 8.5 years) yielded a diagnosis of Parkinson's disease (PD) in 5 and probable multiple system atrophy (MSA) in 3. In 4 patients with an indeterminate diagnosis, cardiac MIBG SPECT was positive in 3, indicating PD, and negative in one, suggesting MSA. Two patients each had psychogenic tremor and drug‐induced parkinsonism. Although lower leg tremor is considered an unusual presentation of PD, it should raise suspicions of MSA and other neurodegenerative disorders. © 2010 Movement Disorder Society</abstract>
<note type="content">*Potential conflict of interest: Nothing to report.</note>
<subject lang="en">
<genre>Keywords</genre>
<topic>tremor</topic>
<topic>Parkinson's disease</topic>
<topic>multiple system atrophy</topic>
<topic>lower limb</topic>
</subject>
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<title>Movement Disorders</title>
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<titleInfo type="abbreviated">
<title>Mov. Disord.</title>
</titleInfo>
<subject>
<genre>article category</genre>
<topic>Brief Report</topic>
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<identifier type="ISSN">0885-3185</identifier>
<identifier type="eISSN">1531-8257</identifier>
<identifier type="DOI">10.1002/(ISSN)1531-8257</identifier>
<identifier type="PublisherID">MDS</identifier>
<part>
<date>2010</date>
<detail type="volume">
<caption>vol.</caption>
<number>25</number>
</detail>
<detail type="issue">
<caption>no.</caption>
<number>7</number>
</detail>
<extent unit="pages">
<start>924</start>
<end>927</end>
<total>4</total>
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<identifier type="DOI">10.1002/mds.23030</identifier>
<identifier type="ArticleID">MDS23030</identifier>
<accessCondition type="use and reproduction" contentType="copyright">Copyright © 2010 Movement Disorder Society</accessCondition>
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