Cardiovascular risk factors in restless legs syndrome
Identifieur interne : 002415 ( Main/Exploration ); précédent : 002414; suivant : 002416Cardiovascular risk factors in restless legs syndrome
Auteurs : Ilana Schlesinger [Israël] ; Ilana Erikh [Israël] ; Ophir Avizohar [Israël] ; Elliot Sprecher [Israël] ; David Yarnitsky [Israël]Source :
- Movement Disorders [ 0885-3185 ] ; 2009-08-15.
Descripteurs français
- Pascal (Inist)
English descriptors
- KwdEn :
- Anemia (epidemiology), Anthropometry, BMI, Body Mass Index, Cardiovascular Diseases (epidemiology), Cardiovascular disease, Comorbidity, Cross-Sectional Studies, Female, Hematocrit, Humans, Hypercholesterolemia (epidemiology), Hyperglycemia (epidemiology), Hyperlipemia, Hypertension (epidemiology), Kidney Diseases (epidemiology), Lipids, Male, Middle Aged, Nervous system diseases, Physical Fitness, Prevalence, Questionnaires, Restless Legs Syndrome (blood), Restless Legs Syndrome (epidemiology), Restless legs syndrome, Risk Factors, Risk factor, Sex Distribution, Smoking (epidemiology), cardiovascular, hyperlipidemia, prevalence, restless legs syndrome.
- MESH :
- blood : Restless Legs Syndrome.
- epidemiology : Anemia, Cardiovascular Diseases, Hypercholesterolemia, Hyperglycemia, Hypertension, Kidney Diseases, Restless Legs Syndrome, Smoking.
- Anthropometry, Body Mass Index, Comorbidity, Cross-Sectional Studies, Female, Hematocrit, Humans, Male, Middle Aged, Physical Fitness, Questionnaires, Risk Factors, Sex Distribution.
Abstract
We conducted a population‐based cross‐sectional study to assess prevalence of cardiovascular risk factors in subjects with and without restless legs syndrome (RLS). Adults attending their annual checkup completed the International RLS Study Group questionnaire and underwent an interview by a neurologist. Data from the annual checkup were compared between subjects with and without RLS. The prevalence of RLS was 6.7% (95% CI 5.45–7.95) among 1,537 responders. RLS subjects' blood tests showed significantly higher fasting blood glucose level (P = 0.029), higher prevalence of hypercholesterolemia (P = 0.029) and reduced renal function (P = 0.013), and increased prevalence of low hematocrit (P = 0.008). RLS subjects weighed more (P = 0.029), had a higher BMI (P = 0.033), larger hip circumference (P = 0.033), and were less fit (P = 0.010). To control for interactions among statistical predictors, we also employed multivariate logistic regression models adjusted for age, gender, smoking, BMI, hemoglobin, glucose, HDL/LDL cholesterol, triglycerides, and creatinine. We found that female gender (OR 2.16; 95% CI 1.11–4.17), smoking (OR 1.82; 95% CI, 1.10–3.00), and HDL/LDL cholesterol (OR 0.18; 95% CI 0.034–0.90) were significantly associated with RLS compared with subjects without RLS. RLS was associated with cardiovascular risk factors. © 2009 Movement Disorder Society
Url:
DOI: 10.1002/mds.22486
Affiliations:
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<front><div type="abstract" xml:lang="en">We conducted a population‐based cross‐sectional study to assess prevalence of cardiovascular risk factors in subjects with and without restless legs syndrome (RLS). Adults attending their annual checkup completed the International RLS Study Group questionnaire and underwent an interview by a neurologist. Data from the annual checkup were compared between subjects with and without RLS. The prevalence of RLS was 6.7% (95% CI 5.45–7.95) among 1,537 responders. RLS subjects' blood tests showed significantly higher fasting blood glucose level (P = 0.029), higher prevalence of hypercholesterolemia (P = 0.029) and reduced renal function (P = 0.013), and increased prevalence of low hematocrit (P = 0.008). RLS subjects weighed more (P = 0.029), had a higher BMI (P = 0.033), larger hip circumference (P = 0.033), and were less fit (P = 0.010). To control for interactions among statistical predictors, we also employed multivariate logistic regression models adjusted for age, gender, smoking, BMI, hemoglobin, glucose, HDL/LDL cholesterol, triglycerides, and creatinine. We found that female gender (OR 2.16; 95% CI 1.11–4.17), smoking (OR 1.82; 95% CI, 1.10–3.00), and HDL/LDL cholesterol (OR 0.18; 95% CI 0.034–0.90) were significantly associated with RLS compared with subjects without RLS. RLS was associated with cardiovascular risk factors. © 2009 Movement Disorder Society</div>
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