Olfactory loss may be a first sign of idiopathic Parkinson's disease
Identifieur interne : 002D07 ( Main/Exploration ); précédent : 002D06; suivant : 002D08Olfactory loss may be a first sign of idiopathic Parkinson's disease
Auteurs : Antje Haehner [Allemagne] ; Thomas Hummel [Allemagne] ; Cornelia Hummel [Allemagne] ; Ulrike Sommer [Allemagne] ; Susann Junghanns [Allemagne] ; Heinz Reichmann [Allemagne]Source :
- Movement Disorders [ 0885-3185 ] ; 2007-04-30.
Descripteurs français
- Pascal (Inist)
English descriptors
- KwdEn :
- Agnosia (etiology), Anosmia, Follow-Up Studies, Humans, Idiopathic, Nervous system diseases, Olfaction, Parkinson Disease (classification), Parkinson Disease (diagnosis), Parkinson Disease (radionuclide imaging), Parkinson disease, Reagent Kits, Diagnostic, Sign, Smell (physiology), Taste, Tomography, Emission-Computed, Single-Photon, anosmia, neurodegeneration, olfaction, smell.
- MESH :
- chemical : Reagent Kits, Diagnostic.
- classification : Parkinson Disease.
- diagnosis : Parkinson Disease.
- etiology : Agnosia.
- physiology : Smell.
- radionuclide imaging : Parkinson Disease.
- Follow-Up Studies, Humans, Taste, Tomography, Emission-Computed, Single-Photon.
Abstract
Recent studies support the idea of olfactory dysfunction as a very early sign of idiopathic Parkinson's disease (IPD). Aim of the present study was to clinically follow‐up patients with idiopathic hyposmia to find out the percentage of patients developing IPD after 4 years time. At baseline, olfactory tests had been combined with transcranial sonography of the substantia nigra and 123I‐FP‐CIT SPECT imaging. At the present neurological examination, 7% of the individuals with idiopathic hyposmia had developed clinical IPD. Altogether, 13% presented with abnormalities of the motor system. Our data suggest that a combination of olfactory testing and other tests may constitute a screening tool for the risk to develop IPD. © 2007 Movement Disorder Society
Url:
DOI: 10.1002/mds.21413
Affiliations:
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Aim of the present study was to clinically follow‐up patients with idiopathic hyposmia to find out the percentage of patients developing IPD after 4 years time. At baseline, olfactory tests had been combined with transcranial sonography of the substantia nigra and 123I‐FP‐CIT SPECT imaging. At the present neurological examination, 7% of the individuals with idiopathic hyposmia had developed clinical IPD. Altogether, 13% presented with abnormalities of the motor system. Our data suggest that a combination of olfactory testing and other tests may constitute a screening tool for the risk to develop IPD. © 2007 Movement Disorder Society</div></front></TEI><affiliations><list><country><li>Allemagne</li></country></list><tree><country name="Allemagne"><noRegion><name sortKey="Haehner, Antje" sort="Haehner, Antje" uniqKey="Haehner A" first="Antje" last="Haehner">Antje Haehner</name></noRegion><name sortKey="Haehner, Antje" sort="Haehner, Antje" uniqKey="Haehner A" first="Antje" last="Haehner">Antje Haehner</name><name sortKey="Hummel, Cornelia" sort="Hummel, Cornelia" uniqKey="Hummel C" first="Cornelia" last="Hummel">Cornelia Hummel</name><name sortKey="Hummel, Thomas" sort="Hummel, Thomas" uniqKey="Hummel T" first="Thomas" last="Hummel">Thomas Hummel</name><name sortKey="Junghanns, Susann" sort="Junghanns, Susann" uniqKey="Junghanns S" first="Susann" last="Junghanns">Susann Junghanns</name><name sortKey="Reichmann, Heinz" sort="Reichmann, Heinz" uniqKey="Reichmann H" first="Heinz" last="Reichmann">Heinz Reichmann</name><name sortKey="Sommer, Ulrike" sort="Sommer, Ulrike" uniqKey="Sommer U" first="Ulrike" last="Sommer">Ulrike Sommer</name></country></tree></affiliations></record>Pour manipuler ce document sous Unix (Dilib)
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