MovDisordV3, PascalFrancis, Curation, bibRecord, 001625

Olfactory loss may be a first sign of idiopathic Parkinson's disease

Identifieur interne : 001625 ( PascalFrancis/Curation ); précédent : 001624; suivant : 001626

Olfactory loss may be a first sign of idiopathic Parkinson's disease

Auteurs : Antje Haehner [Allemagne] ; Thomas Hummel [Allemagne] ; Cornelia Hummel [Allemagne] ; Ulrike Sommer [Allemagne] ; Susann Junghanns [Allemagne] ; Heinz Reichmann [Allemagne]

Source :

Movement disorders [ 0885-3185 ] ; 2007.

RBID : Pascal:07-0263061

Descripteurs français

Pascal (Inist)
- Système nerveux pathologie, Parkinson maladie, Anosmie, Signe, Idiopathique, Olfaction.

English descriptors

KwdEn :
- Anosmia, Idiopathic, Nervous system diseases, Olfaction, Parkinson disease, Sign.

Abstract

Recent studies support the idea of olfactory dysfunction as a very early sign of idiopathic Parkinson's disease (IPD). Aim of the present study was to clinically follow-up patients with idiopathic hyposmia to find out the percentage of patients developing IPD after 4 years time. At baseline, olfactory tests had been combined with transcranial sonography of the substantia nigra and ¹²³I-FP-CIT SPECT imaging. At the present neurological examination, 7% of the individuals with idiopathic hyposmia had developed clinical IPD. Altogether, 13% presented with abnormalities of the motor system. Our data suggest that a combination of olfactory testing and other tests may constitute a screening tool for the risk to develop IPD.

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A08	`01`	`1`	`ENG`	`@1 Olfactory loss may be a first sign of idiopathic Parkinson's disease`
A11	`01`	`1`		`@1 HAEHNER (Antje)`
A11	`02`	`1`		`@1 HUMMEL (Thomas)`
A11	`03`	`1`		`@1 HUMMEL (Cornelia)`
A11	`04`	`1`		`@1 SOMMER (Ulrike)`
A11	`05`	`1`		`@1 JUNGHANNS (Susann)`
A11	`06`	`1`		`@1 REICHMANN (Heinz)`
A14	`01`			`@1 Department of Neurology, University of Dresden Medical School @3 DEU @Z 1 aut. @Z 4 aut. @Z 5 aut. @Z 6 aut.`
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C01	`01`		`ENG`	@0 Recent studies support the idea of olfactory dysfunction as a very early sign of idiopathic Parkinson's disease (IPD). Aim of the present study was to clinically follow-up patients with idiopathic hyposmia to find out the percentage of patients developing IPD after 4 years time. At baseline, olfactory tests had been combined with transcranial sonography of the substantia nigra and ¹²³I-FP-CIT SPECT imaging. At the present neurological examination, 7% of the individuals with idiopathic hyposmia had developed clinical IPD. Altogether, 13% presented with abnormalities of the motor system. Our data suggest that a combination of olfactory testing and other tests may constitute a screening tool for the risk to develop IPD.
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C03	`01`	`X`	`ENG`	`@0 Nervous system diseases @5 01`
C03	`01`	`X`	`SPA`	`@0 Sistema nervioso patología @5 01`
C03	`02`	`X`	`FRE`	`@0 Parkinson maladie @5 02`
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C03	`02`	`X`	`SPA`	`@0 Parkinson enfermedad @5 02`
C03	`03`	`X`	`FRE`	`@0 Anosmie @5 03`
C03	`03`	`X`	`ENG`	`@0 Anosmia @5 03`
C03	`03`	`X`	`SPA`	`@0 Anosmia @5 03`
C03	`04`	`X`	`FRE`	`@0 Signe @5 09`
C03	`04`	`X`	`ENG`	`@0 Sign @5 09`
C03	`04`	`X`	`SPA`	`@0 Signo @5 09`
C03	`05`	`X`	`FRE`	`@0 Idiopathique @5 10`
C03	`05`	`X`	`ENG`	`@0 Idiopathic @5 10`
C03	`05`	`X`	`SPA`	`@0 Idiopático @5 10`
C03	`06`	`X`	`FRE`	`@0 Olfaction @5 11`
C03	`06`	`X`	`ENG`	`@0 Olfaction @5 11`
C03	`06`	`X`	`SPA`	`@0 Olfación @5 11`
C07	`01`	`X`	`FRE`	`@0 Encéphale pathologie @5 37`
C07	`01`	`X`	`ENG`	`@0 Cerebral disorder @5 37`
C07	`01`	`X`	`SPA`	`@0 Encéfalo patología @5 37`
C07	`02`	`X`	`FRE`	`@0 Extrapyramidal syndrome @5 38`
C07	`02`	`X`	`ENG`	`@0 Extrapyramidal syndrome @5 38`
C07	`02`	`X`	`SPA`	`@0 Extrapiramidal síndrome @5 38`
C07	`03`	`X`	`FRE`	`@0 Maladie dégénérative @5 39`
C07	`03`	`X`	`ENG`	`@0 Degenerative disease @5 39`
C07	`03`	`X`	`SPA`	`@0 Enfermedad degenerativa @5 39`
C07	`04`	`X`	`FRE`	`@0 Système nerveux central pathologie @5 40`
C07	`04`	`X`	`ENG`	`@0 Central nervous system disease @5 40`
C07	`04`	`X`	`SPA`	`@0 Sistema nervosio central patología @5 40`
C07	`05`	`X`	`FRE`	`@0 Trouble neurologique @5 41`
C07	`05`	`X`	`ENG`	`@0 Neurological disorder @5 41`
C07	`05`	`X`	`SPA`	`@0 Trastorno neurológico @5 41`
C07	`06`	`X`	`FRE`	`@0 Trouble odorat @5 42`
C07	`06`	`X`	`ENG`	`@0 Olfactory disorder @5 42`
C07	`06`	`X`	`SPA`	`@0 Trastorno olfatorio @5 42`
N21				`@1 176`
N44	`01`			`@1 OTO`
N82				`@1 OTO`

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Pascal:07-0263061

Le document en format XML

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<front><div type="abstract" xml:lang="en">Recent studies support the idea of olfactory dysfunction as a very early sign of idiopathic Parkinson's disease (IPD). Aim of the present study was to clinically follow-up patients with idiopathic hyposmia to find out the percentage of patients developing IPD after 4 years time. At baseline, olfactory tests had been combined with transcranial sonography of the substantia nigra and <sup>123</sup>
I-FP-CIT SPECT imaging. At the present neurological examination, 7% of the individuals with idiopathic hyposmia had developed clinical IPD. Altogether, 13% presented with abnormalities of the motor system. Our data suggest that a combination of olfactory testing and other tests may constitute a screening tool for the risk to develop IPD.</div>
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I-FP-CIT SPECT imaging. At the present neurological examination, 7% of the individuals with idiopathic hyposmia had developed clinical IPD. Altogether, 13% presented with abnormalities of the motor system. Our data suggest that a combination of olfactory testing and other tests may constitute a screening tool for the risk to develop IPD.</s0>
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<s5>39</s5>
</fC07>
<fC07 i1="03" i2="X" l="SPA"><s0>Enfermedad degenerativa</s0>
<s5>39</s5>
</fC07>
<fC07 i1="04" i2="X" l="FRE"><s0>Système nerveux central pathologie</s0>
<s5>40</s5>
</fC07>
<fC07 i1="04" i2="X" l="ENG"><s0>Central nervous system disease</s0>
<s5>40</s5>
</fC07>
<fC07 i1="04" i2="X" l="SPA"><s0>Sistema nervosio central patología</s0>
<s5>40</s5>
</fC07>
<fC07 i1="05" i2="X" l="FRE"><s0>Trouble neurologique</s0>
<s5>41</s5>
</fC07>
<fC07 i1="05" i2="X" l="ENG"><s0>Neurological disorder</s0>
<s5>41</s5>
</fC07>
<fC07 i1="05" i2="X" l="SPA"><s0>Trastorno neurológico</s0>
<s5>41</s5>
</fC07>
<fC07 i1="06" i2="X" l="FRE"><s0>Trouble odorat</s0>
<s5>42</s5>
</fC07>
<fC07 i1="06" i2="X" l="ENG"><s0>Olfactory disorder</s0>
<s5>42</s5>
</fC07>
<fC07 i1="06" i2="X" l="SPA"><s0>Trastorno olfatorio</s0>
<s5>42</s5>
</fC07>
<fN21><s1>176</s1>
</fN21>
<fN44 i1="01"><s1>OTO</s1>
</fN44>
<fN82><s1>OTO</s1>
</fN82>
</pA>
</standard>
</inist>
</record>

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   |texte=   Olfactory loss may be a first sign of idiopathic Parkinson's disease
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	Movement Disorders (revue)
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Movement Disorders (revue)

Olfactory loss may be a first sign of idiopathic Parkinson's disease

Olfactory loss may be a first sign of idiopathic Parkinson's disease

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