Positron emission tomographic studies in restless legs syndrome
Identifieur interne : 004C72 ( Main/Exploration ); précédent : 004C71; suivant : 004C73Positron emission tomographic studies in restless legs syndrome
Auteurs : Claudia Trenkwalder [Allemagne] ; Arthur S. Walters [États-Unis] ; Wayne A. Hening [États-Unis] ; Sudhansu Chokroverty [États-Unis] ; Angelo Antonini [États-Unis] ; Vijay Dhawan [États-Unis] ; David Eidelberg [États-Unis]Source :
- Movement Disorders [ 0885-3185 ] ; 1999-01.
Descripteurs français
- Pascal (Inist)
- Wicri :
- topic : Adulte.
English descriptors
- KwdEn :
- Adult, Aged, Brain (physiopathology), Brain (radionuclide imaging), Dihydroxyphenylalanine (analogs & derivatives), Dihydroxyphenylalanine (diagnostic use), Dopamine receptor, Emission tomography, Energy Metabolism (physiology), Female, Fluorodeoxyglucose, Fluorodeoxyglucose F18 (diagnostic use), Fluorodopa, Fluorodopa(18F), Humans, Local cerebral glucose utilization, Male, Metabolism, Middle Aged, Pathogenesis, Periodic limb movements (PLM), Positron, Positron emission tomography (PET), Radionuclide study, Receptors, Dopamine (physiology), Receptors, Presynaptic (physiology), Restless Legs Syndrome (physiopathology), Restless Legs Syndrome (radionuclide imaging), Restless legs syndrome, Restless legs syndrome (RLS), Sleep disorders, Tomography, Emission-Computed.
- MESH :
- chemical , analogs & derivatives : Dihydroxyphenylalanine.
- chemical , diagnostic use : Dihydroxyphenylalanine, Fluorodeoxyglucose F18.
- physiology : Energy Metabolism, Receptors, Dopamine, Receptors, Presynaptic.
- physiopathology : Brain, Restless Legs Syndrome.
- radionuclide imaging : Brain, Restless Legs Syndrome.
- Aged, Female, Humans, Male, Middle Aged, Tomography, Emission-Computed.
Abstract
We studied six restless legs syndrome (RLS) patients with [F18]fluorodeoxyglucose (FDG) positron emission tomography (PET). We also studied four of these same patients with [F18]fluorodopa (FDOPA) PET. The patients' FDG and FDOPA PET scans were compared with those from age‐matched healthy control subjects. No significant differences between the two groups were found for any regional blood flow values derived from the FDG scans or for any binding constants derived from the FDOPA scans. These results suggest that any abnormal resting brain metabolic activity or putative presynaptic dopaminergic defect in RLS is likely either to be so subtle that it is below the threshold for ready detection by PET or that it is located in an area of neural tissue inaccessible to the current scanner. No substantial defect is likely to involve the dopaminergic nigrostriatal axis.
Url:
DOI: 10.1002/1531-8257(199901)14:1<141::AID-MDS1024>3.0.CO;2-B
Affiliations:
Links toward previous steps (curation, corpus...)
- to stream Istex, to step Corpus: 002A30
- to stream Istex, to step Curation: 002A30
- to stream Istex, to step Checkpoint: 003439
- to stream Main, to step Merge: 007971
- to stream PascalFrancis, to step Corpus: 002E95
- to stream PascalFrancis, to step Curation: 003929
- to stream PascalFrancis, to step Checkpoint: 002D46
- to stream Main, to step Merge: 007B95
- to stream PubMed, to step Corpus: 004274
- to stream PubMed, to step Curation: 004274
- to stream PubMed, to step Checkpoint: 004134
- to stream Ncbi, to step Merge: 005110
- to stream Ncbi, to step Curation: 005110
- to stream Ncbi, to step Checkpoint: 005110
- to stream Main, to step Merge: 007741
- to stream Main, to step Curation: 004C72
Le document en format XML
<record><TEI wicri:istexFullTextTei="biblStruct"><teiHeader><fileDesc><titleStmt><title xml:lang="en">Positron emission tomographic studies in restless legs syndrome</title>
<author><name sortKey="Trenkwalder, Claudia" sort="Trenkwalder, Claudia" uniqKey="Trenkwalder C" first="Claudia" last="Trenkwalder">Claudia Trenkwalder</name>
</author>
<author><name sortKey="Walters, Arthur S" sort="Walters, Arthur S" uniqKey="Walters A" first="Arthur S." last="Walters">Arthur S. Walters</name>
</author>
<author><name sortKey="Hening, Wayne A" sort="Hening, Wayne A" uniqKey="Hening W" first="Wayne A." last="Hening">Wayne A. Hening</name>
</author>
<author><name sortKey="Chokroverty, Sudhansu" sort="Chokroverty, Sudhansu" uniqKey="Chokroverty S" first="Sudhansu" last="Chokroverty">Sudhansu Chokroverty</name>
</author>
<author><name sortKey="Antonini, Angelo" sort="Antonini, Angelo" uniqKey="Antonini A" first="Angelo" last="Antonini">Angelo Antonini</name>
</author>
<author><name sortKey="Dhawan, Vijay" sort="Dhawan, Vijay" uniqKey="Dhawan V" first="Vijay" last="Dhawan">Vijay Dhawan</name>
</author>
<author><name sortKey="Eidelberg, David" sort="Eidelberg, David" uniqKey="Eidelberg D" first="David" last="Eidelberg">David Eidelberg</name>
</author>
</titleStmt>
<publicationStmt><idno type="wicri:source">ISTEX</idno>
<idno type="RBID">ISTEX:40F9C1EEE3E5C17FE336545F551138275DB655AB</idno>
<date when="1999" year="1999">1999</date>
<idno type="doi">10.1002/1531-8257(199901)14:1<141::AID-MDS1024>3.0.CO;2-B</idno>
<idno type="url">https://api.istex.fr/document/40F9C1EEE3E5C17FE336545F551138275DB655AB/fulltext/pdf</idno>
<idno type="wicri:Area/Istex/Corpus">002A30</idno>
<idno type="wicri:Area/Istex/Curation">002A30</idno>
<idno type="wicri:Area/Istex/Checkpoint">003439</idno>
<idno type="wicri:doubleKey">0885-3185:1999:Trenkwalder C:positron:emission:tomographic</idno>
<idno type="wicri:Area/Main/Merge">007971</idno>
<idno type="wicri:source">INIST</idno>
<idno type="RBID">Pascal:99-0084668</idno>
<idno type="wicri:Area/PascalFrancis/Corpus">002E95</idno>
<idno type="wicri:Area/PascalFrancis/Curation">003929</idno>
<idno type="wicri:Area/PascalFrancis/Checkpoint">002D46</idno>
<idno type="wicri:doubleKey">0885-3185:1999:Trenkwalder C:positron:emission:tomographic</idno>
<idno type="wicri:Area/Main/Merge">007B95</idno>
<idno type="wicri:source">PubMed</idno>
<idno type="RBID">pubmed:9918358</idno>
<idno type="wicri:Area/PubMed/Corpus">004274</idno>
<idno type="wicri:Area/PubMed/Curation">004274</idno>
<idno type="wicri:Area/PubMed/Checkpoint">004134</idno>
<idno type="wicri:Area/Ncbi/Merge">005110</idno>
<idno type="wicri:Area/Ncbi/Curation">005110</idno>
<idno type="wicri:Area/Ncbi/Checkpoint">005110</idno>
<idno type="wicri:doubleKey">0885-3185:1999:Trenkwalder C:positron:emission:tomographic</idno>
<idno type="wicri:Area/Main/Merge">007741</idno>
<idno type="wicri:Area/Main/Curation">004C72</idno>
<idno type="wicri:Area/Main/Exploration">004C72</idno>
</publicationStmt>
<sourceDesc><biblStruct><analytic><title level="a" type="main" xml:lang="en">Positron emission tomographic studies in restless legs syndrome</title>
<author><name sortKey="Trenkwalder, Claudia" sort="Trenkwalder, Claudia" uniqKey="Trenkwalder C" first="Claudia" last="Trenkwalder">Claudia Trenkwalder</name>
<affiliation wicri:level="3"><country xml:lang="fr">Allemagne</country>
<wicri:regionArea>Department of Neurology, Max‐Planck‐Institute of Psychiatry, Munich</wicri:regionArea>
<placeName><region type="land" nuts="1">Bavière</region>
<region type="district" nuts="2">District de Haute-Bavière</region>
<settlement type="city">Munich</settlement>
</placeName>
</affiliation>
</author>
<author><name sortKey="Walters, Arthur S" sort="Walters, Arthur S" uniqKey="Walters A" first="Arthur S." last="Walters">Arthur S. Walters</name>
<affiliation wicri:level="2"><country xml:lang="fr">États-Unis</country>
<placeName><region type="state">New Jersey</region>
</placeName>
<wicri:cityArea>Department of Neurology, University of Medicine and Dentistry of New Jersey, Robert Wood Johnson Medical School, New Brunswick</wicri:cityArea>
</affiliation>
<affiliation wicri:level="2"><country xml:lang="fr">États-Unis</country>
<placeName><region type="state">New Jersey</region>
</placeName>
<wicri:cityArea>Neurology Service, VA Medical Center, Lyons</wicri:cityArea>
</affiliation>
</author>
<author><name sortKey="Hening, Wayne A" sort="Hening, Wayne A" uniqKey="Hening W" first="Wayne A." last="Hening">Wayne A. Hening</name>
<affiliation wicri:level="2"><country xml:lang="fr">États-Unis</country>
<placeName><region type="state">New Jersey</region>
</placeName>
<wicri:cityArea>Department of Neurology, University of Medicine and Dentistry of New Jersey, Robert Wood Johnson Medical School, New Brunswick</wicri:cityArea>
</affiliation>
<affiliation wicri:level="2"><country xml:lang="fr">États-Unis</country>
<placeName><region type="state">New Jersey</region>
</placeName>
<wicri:cityArea>Neurology Service, VA Medical Center, Lyons</wicri:cityArea>
</affiliation>
</author>
<author><name sortKey="Chokroverty, Sudhansu" sort="Chokroverty, Sudhansu" uniqKey="Chokroverty S" first="Sudhansu" last="Chokroverty">Sudhansu Chokroverty</name>
<affiliation wicri:level="2"><country xml:lang="fr">États-Unis</country>
<placeName><region type="state">New Jersey</region>
</placeName>
<wicri:cityArea>Neurology Service, VA Medical Center, Lyons</wicri:cityArea>
</affiliation>
<affiliation wicri:level="2"><country xml:lang="fr">États-Unis</country>
<placeName><region type="state">État de New York</region>
</placeName>
<wicri:cityArea>Department of Neurology, St. Vincent's Hospital, New York City</wicri:cityArea>
</affiliation>
</author>
<author><name sortKey="Antonini, Angelo" sort="Antonini, Angelo" uniqKey="Antonini A" first="Angelo" last="Antonini">Angelo Antonini</name>
<affiliation wicri:level="2"><country xml:lang="fr">États-Unis</country>
<wicri:regionArea>Movement Disorders Center, North Shore University Hospital and New York University School of Medicine, Manhasset, New York</wicri:regionArea>
<placeName><region type="state">État de New York</region>
</placeName>
</affiliation>
</author>
<author><name sortKey="Dhawan, Vijay" sort="Dhawan, Vijay" uniqKey="Dhawan V" first="Vijay" last="Dhawan">Vijay Dhawan</name>
<affiliation wicri:level="2"><country xml:lang="fr">États-Unis</country>
<wicri:regionArea>Movement Disorders Center, North Shore University Hospital and New York University School of Medicine, Manhasset, New York</wicri:regionArea>
<placeName><region type="state">État de New York</region>
</placeName>
</affiliation>
</author>
<author><name sortKey="Eidelberg, David" sort="Eidelberg, David" uniqKey="Eidelberg D" first="David" last="Eidelberg">David Eidelberg</name>
<affiliation wicri:level="2"><country xml:lang="fr">États-Unis</country>
<wicri:regionArea>Movement Disorders Center, North Shore University Hospital and New York University School of Medicine, Manhasset, New York</wicri:regionArea>
<placeName><region type="state">État de New York</region>
</placeName>
</affiliation>
</author>
</analytic>
<monogr></monogr>
<series><title level="j">Movement Disorders</title>
<title level="j" type="sub">Official Journal of the Movement Disorder Society</title>
<title level="j" type="abbrev">Mov. Disord.</title>
<idno type="ISSN">0885-3185</idno>
<idno type="eISSN">1531-8257</idno>
<imprint><publisher>John Wiley & Sons, Inc.</publisher>
<pubPlace>New York</pubPlace>
<date type="published" when="1999-01">1999-01</date>
<biblScope unit="vol">14</biblScope>
<biblScope unit="issue">1</biblScope>
<biblScope unit="page" from="141">141</biblScope>
<biblScope unit="page" to="145">145</biblScope>
</imprint>
<idno type="ISSN">0885-3185</idno>
</series>
<idno type="istex">40F9C1EEE3E5C17FE336545F551138275DB655AB</idno>
<idno type="DOI">10.1002/1531-8257(199901)14:1<141::AID-MDS1024>3.0.CO;2-B</idno>
<idno type="ArticleID">MDS1024</idno>
</biblStruct>
</sourceDesc>
<seriesStmt><idno type="ISSN">0885-3185</idno>
</seriesStmt>
</fileDesc>
<profileDesc><textClass><keywords scheme="KwdEn" xml:lang="en"><term>Adult</term>
<term>Aged</term>
<term>Brain (physiopathology)</term>
<term>Brain (radionuclide imaging)</term>
<term>Dihydroxyphenylalanine (analogs & derivatives)</term>
<term>Dihydroxyphenylalanine (diagnostic use)</term>
<term>Dopamine receptor</term>
<term>Emission tomography</term>
<term>Energy Metabolism (physiology)</term>
<term>Female</term>
<term>Fluorodeoxyglucose</term>
<term>Fluorodeoxyglucose F18 (diagnostic use)</term>
<term>Fluorodopa</term>
<term>Fluorodopa(18F)</term>
<term>Humans</term>
<term>Local cerebral glucose utilization</term>
<term>Male</term>
<term>Metabolism</term>
<term>Middle Aged</term>
<term>Pathogenesis</term>
<term>Periodic limb movements (PLM)</term>
<term>Positron</term>
<term>Positron emission tomography (PET)</term>
<term>Radionuclide study</term>
<term>Receptors, Dopamine (physiology)</term>
<term>Receptors, Presynaptic (physiology)</term>
<term>Restless Legs Syndrome (physiopathology)</term>
<term>Restless Legs Syndrome (radionuclide imaging)</term>
<term>Restless legs syndrome</term>
<term>Restless legs syndrome (RLS)</term>
<term>Sleep disorders</term>
<term>Tomography, Emission-Computed</term>
</keywords>
<keywords scheme="MESH" type="chemical" qualifier="analogs & derivatives" xml:lang="en"><term>Dihydroxyphenylalanine</term>
</keywords>
<keywords scheme="MESH" type="chemical" qualifier="diagnostic use" xml:lang="en"><term>Dihydroxyphenylalanine</term>
<term>Fluorodeoxyglucose F18</term>
</keywords>
<keywords scheme="MESH" qualifier="physiology" xml:lang="en"><term>Energy Metabolism</term>
<term>Receptors, Dopamine</term>
<term>Receptors, Presynaptic</term>
</keywords>
<keywords scheme="MESH" qualifier="physiopathology" xml:lang="en"><term>Brain</term>
<term>Restless Legs Syndrome</term>
</keywords>
<keywords scheme="MESH" qualifier="radionuclide imaging" xml:lang="en"><term>Brain</term>
<term>Restless Legs Syndrome</term>
</keywords>
<keywords scheme="MESH" xml:lang="en"><term>Aged</term>
<term>Female</term>
<term>Humans</term>
<term>Male</term>
<term>Middle Aged</term>
<term>Tomography, Emission-Computed</term>
</keywords>
<keywords scheme="Pascal" xml:lang="fr"><term>Adulte</term>
<term>Exploration radioisotopique</term>
<term>Fluor 18 FDG</term>
<term>Fluorodopa(18F)</term>
<term>Impatience membre inférieur syndrome</term>
<term>Métabolisme</term>
<term>Pathogénie</term>
<term>Positon</term>
<term>Récepteur dopaminergique</term>
<term>Tomoscintigraphie</term>
<term>Utilisation cérébrale locale glucose</term>
</keywords>
<keywords scheme="Wicri" type="topic" xml:lang="fr"><term>Adulte</term>
</keywords>
</textClass>
<langUsage><language ident="en">en</language>
</langUsage>
</profileDesc>
</teiHeader>
<front><div type="abstract" xml:lang="en">We studied six restless legs syndrome (RLS) patients with [F18]fluorodeoxyglucose (FDG) positron emission tomography (PET). We also studied four of these same patients with [F18]fluorodopa (FDOPA) PET. The patients' FDG and FDOPA PET scans were compared with those from age‐matched healthy control subjects. No significant differences between the two groups were found for any regional blood flow values derived from the FDG scans or for any binding constants derived from the FDOPA scans. These results suggest that any abnormal resting brain metabolic activity or putative presynaptic dopaminergic defect in RLS is likely either to be so subtle that it is below the threshold for ready detection by PET or that it is located in an area of neural tissue inaccessible to the current scanner. No substantial defect is likely to involve the dopaminergic nigrostriatal axis.</div>
</front>
</TEI>
<affiliations><list><country><li>Allemagne</li>
<li>États-Unis</li>
</country>
<region><li>Bavière</li>
<li>District de Haute-Bavière</li>
<li>New Jersey</li>
<li>État de New York</li>
</region>
<settlement><li>Munich</li>
</settlement>
</list>
<tree><country name="Allemagne"><region name="Bavière"><name sortKey="Trenkwalder, Claudia" sort="Trenkwalder, Claudia" uniqKey="Trenkwalder C" first="Claudia" last="Trenkwalder">Claudia Trenkwalder</name>
</region>
</country>
<country name="États-Unis"><region name="New Jersey"><name sortKey="Walters, Arthur S" sort="Walters, Arthur S" uniqKey="Walters A" first="Arthur S." last="Walters">Arthur S. Walters</name>
</region>
<name sortKey="Antonini, Angelo" sort="Antonini, Angelo" uniqKey="Antonini A" first="Angelo" last="Antonini">Angelo Antonini</name>
<name sortKey="Chokroverty, Sudhansu" sort="Chokroverty, Sudhansu" uniqKey="Chokroverty S" first="Sudhansu" last="Chokroverty">Sudhansu Chokroverty</name>
<name sortKey="Chokroverty, Sudhansu" sort="Chokroverty, Sudhansu" uniqKey="Chokroverty S" first="Sudhansu" last="Chokroverty">Sudhansu Chokroverty</name>
<name sortKey="Dhawan, Vijay" sort="Dhawan, Vijay" uniqKey="Dhawan V" first="Vijay" last="Dhawan">Vijay Dhawan</name>
<name sortKey="Eidelberg, David" sort="Eidelberg, David" uniqKey="Eidelberg D" first="David" last="Eidelberg">David Eidelberg</name>
<name sortKey="Hening, Wayne A" sort="Hening, Wayne A" uniqKey="Hening W" first="Wayne A." last="Hening">Wayne A. Hening</name>
<name sortKey="Hening, Wayne A" sort="Hening, Wayne A" uniqKey="Hening W" first="Wayne A." last="Hening">Wayne A. Hening</name>
<name sortKey="Walters, Arthur S" sort="Walters, Arthur S" uniqKey="Walters A" first="Arthur S." last="Walters">Arthur S. Walters</name>
</country>
</tree>
</affiliations>
</record>
Pour manipuler ce document sous Unix (Dilib)
EXPLOR_STEP=$WICRI_ROOT/Wicri/Santé/explor/MovDisordV3/Data/Main/Exploration
HfdSelect -h $EXPLOR_STEP/biblio.hfd -nk 004C72 | SxmlIndent | more
Ou
HfdSelect -h $EXPLOR_AREA/Data/Main/Exploration/biblio.hfd -nk 004C72 | SxmlIndent | more
Pour mettre un lien sur cette page dans le réseau Wicri
{{Explor lien |wiki= Wicri/Santé |area= MovDisordV3 |flux= Main |étape= Exploration |type= RBID |clé= ISTEX:40F9C1EEE3E5C17FE336545F551138275DB655AB |texte= Positron emission tomographic studies in restless legs syndrome }}
![]() | This area was generated with Dilib version V0.6.23. | ![]() |