Movement Disorders (revue)

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Dopamine D2 receptor TaqIA and TaqIB polymorphisms in Parkinson's disease

Identifieur interne : 004122 ( Main/Exploration ); précédent : 004121; suivant : 004123

Dopamine D2 receptor TaqIA and TaqIB polymorphisms in Parkinson's disease

Auteurs : Eng-King Tan [Singapour] ; Yanni Tan [Singapour] ; Anthea Chai [Singapour] ; Christopher Tan [Singapour] ; Hui Shen [Singapour] ; Sau-Ying Lum [Singapour] ; Stephanie M. C. Fook-Cheong [Singapour] ; Mei-Ling Teoh [Singapour] ; Yuan Yih [Singapour] ; Meng-Cheong Wong [Singapour] ; Yi Zhao [Singapour]

Source :

RBID : ISTEX:0C1E01E57BAB424D6CB7054B76BA502BEEF09DB8

Descripteurs français

English descriptors

Abstract

In a case control study, we examined the association of DRD2 Taq1A and Taq1B polymorphisms and risk of PD, and evaluated the strength of linkage disequilibrium of the polymorphisms. The Taq1A and Taq1B polymorphisms were in strong linkage disequilibrium. There was, however, no significant association of the two polymorphisms with PD. © 2003 Movement Disorder Society

Url:
DOI: 10.1002/mds.10406


Affiliations:


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Le document en format XML

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<term>DNA Primers (genetics)</term>
<term>Female</term>
<term>Gene Frequency (genetics)</term>
<term>Genetic Markers</term>
<term>Genetic Predisposition to Disease</term>
<term>Genotype</term>
<term>Human</term>
<term>Humans</term>
<term>Linkage</term>
<term>Linkage Disequilibrium (genetics)</term>
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<term>Middle Aged</term>
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<term>Parkinson disease</term>
<term>Parkinson's disease</term>
<term>Polymorphism</term>
<term>Polymorphism, Genetic (genetics)</term>
<term>Receptors, Dopamine D2 (genetics)</term>
<term>Risk factor</term>
<term>Taq Polymerase (classification)</term>
<term>Taq Polymerase (genetics)</term>
<term>dopamine receptor D2</term>
<term>polymorphism</term>
<term>smoking</term>
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<term>Liaison génétique</term>
<term>Parkinson maladie</term>
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<term>Récepteur dopaminergique D2</term>
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<div type="abstract" xml:lang="en">In a case control study, we examined the association of DRD2 Taq1A and Taq1B polymorphisms and risk of PD, and evaluated the strength of linkage disequilibrium of the polymorphisms. The Taq1A and Taq1B polymorphisms were in strong linkage disequilibrium. There was, however, no significant association of the two polymorphisms with PD. © 2003 Movement Disorder Society</div>
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<name sortKey="Tan, Yanni" sort="Tan, Yanni" uniqKey="Tan Y" first="Yanni" last="Tan">Yanni Tan</name>
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<name sortKey="Wong, Meng Heong" sort="Wong, Meng Heong" uniqKey="Wong M" first="Meng-Cheong" last="Wong">Meng-Cheong Wong</name>
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