Movement Disorders (revue)

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Symptoms and duration of the prodromal phase in parkinson's disease

Identifieur interne : 005249 ( Main/Exploration ); précédent : 005248; suivant : 005250

Symptoms and duration of the prodromal phase in parkinson's disease

Auteurs : Ed G. Gonera [Pays-Bas] ; Martin Van'T Hof [Pays-Bas] ; Hans J. C. Berger [Pays-Bas] ; Chris Van Weel [Pays-Bas] ; Horstink [Pays-Bas]

Source :

RBID : ISTEX:272AF50BC9F94B8233CBFC32F1D7A88ABF43F63F

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English descriptors

Abstract

To investigate the duration of a prodromal phase before the onset of the classic symptoms of idiopathic Parkinson's disease the authors conducted a retrospective case control study of 60 patients with Parkinson's disease and 58 age‐ and sex‐matched control subjects, covering the decade preceding the onset of classic Parkinson's disease. The symptoms were derived from files of the patients general practitioners. Compared with control subjects, patients pre‐Parkinson's disease had more central nervous system, psychologic, musculoskeletal, and cardiovascular (i.e., autonomic) symptoms. Patients pre‐Parkinson's disease also made more visits to general practitioners and medical specialists. The results indicate that the onset of classic parkinsonism is frequently precede by a prodromal phase lasting from 4–6 years.

Url:
DOI: 10.1002/mds.870120607


Affiliations:


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Le document en format XML

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